2,049 search results for “chemical industry” in the Public website
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Niki van Stein
Science
n.van.stein@liacs.leidenuniv.nl | +31 71 527 2727
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Svetlana Kharchenkova
Faculty of Humanities
s.s.kharchenkova@hum.leidenuniv.nl | +31 71 527 1180
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Systems microscopy to unravel cellular stress response signalling in drug induced liver injury
Promotor: B. van de Water
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The advantages and disadvantages of bioorthogonal proteins
This thesis describes the use of bioorthogonal proteins in immunological settings. It provides an introduction towards the field of protein modification, which was used throughout the thesis for the expression of proteins containing unnatural amino acids.
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Gene regulation in embryonic development
The human body consists of hundreds, perhaps thousands of different types of cells, each with different morphologies and functions, despite having the same genome.
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Targeting of antigen-presenting cells with mannosylated conjugates
This thesis describes the development of a variety of mannosylated conjugates. Antigen presenting cells bear mannoside recognizing receptors that actively transport antigen into the cell. This thesis exploits this feature for the development of improved vaccines.
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Non-equilibrium chemistry and cooling in simulations of galaxy formation
Promotor: J. Schaye
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Gerard van Westen: 'Our model predicts what candidate drugs do in your body'
He’s a fast and animated speaker, which is only logical because Gerard van Westen is driving an express train. His destination? A virtual human, consisting of algorithms that predict what an administered substance will do in the body. The train is already a long way down the line and the pharmaceutical…
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Internships
The SBB Internship is a great Opportunity for both Students and Organisations: Almost all SBB students look back upon their internship with positive feelings, since it is a valuable experience.
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Board column: Come to the debate on our ties with the fossil fuel industry on 27 September
Our students and staff have strong feelings and deep concerns about the ties between Dutch universities and the fossil fuel industry. It’s a thorny issue and as a university we’re keen to chart our course for the future, but we cannot do so alone. I therefore hope to be able to discuss the matter with…
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New insight brings sustainable hydrogen one step closer
Leiden chemists Marc Koper and Ian McCrum have discovered that the degree to which a metal binds to the oxygen atom of water is decisive for how well the chemical conversion of water to molecular hydrogen takes place. This insight helps to develop better catalysts for the production of sustainable hydrogen,…
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Fundamental and translational medical biochemistry
Through metabolism, biochemical processes give rise to the complexity of life. Acquired and inborn errors in metabolism underlie many diseases occurring in man. The challenge for present day medical biochemistry is to find, and integrate, pieces of information at molecular, cell and organismal level…
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Teaching
At Molecular Physiology we teach the following courses within the Leiden Institute of Chemistry's Chemistry and Life Science and Technology programmes.
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LIFE-GREENAPI
Development & demonstration of low environmental impact innovation and optimization practices in pharma production.
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Research shows protein movement is important
Researchers led by Professor of Chemistry Marcellus Ubbink have recently published a study in Proceedings of the National Academy of Sciences (PNAS) about the dynamics of an important redox enzyme. This work was accomplished thanks to an NWO VICI subsidy granted to Professor Ubbink.
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Surface Reactivity of Activated CO2 Selective use of energy in splitting CO2
Juurlink
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Green defense against thrips- Exploring natural products for early management of western flower thrips
As a contribution to the changing legislation and evolving societal attitudes concerning environmental issues, this project aims to enhance and manipulate the plants’ own natural defense mechanisms against western flower thrips (WFT).
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Bioorthogonal Chemistry: Applications in Activity-Based Protein Profiling
The close interaction between organic chemi stry and biology goes back to the late 18th century, when the modern natural sciences began to take shape. After synthetic organic chemistry arose as a discipline, organic chemists almost immediately began to pursue the synthesis of naturally occurring compounds,…
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CML researcher David Font Vivanco won the Graedel Prize 2014
PhD researcher David Font Vivanco, together with Ester van der Voet, Reinout Heijungs and Renée Kemp (Maastricht University) won the Graedel Prize 2014 for best paper published by a junior author in the Journal of Industrial Ecology.
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Chemistry in embedded disks: setting the stage for planet formation
To address the fundamental questions of how life on Earth emerged and how common life may be in the Universe, it is crucial to know the chemical composition of the planet-forming material.
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Shining Light on Interstellar Matter
Promotor: H.V.J. Linnartz
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Giant barrel sponges in diverse habitats: a story about the metabolome
Marine sponges are important members of reef ecosystems, as they play ecological roles that are essential for the health of the reef.
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LED3 Lecture: Translational Chemical Biology
Lecture
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Laboratory for Astrophysics
We simulate interstellar clouds with special plasma expansions and chemical reactions on icy dust grains to be measured in ultra-high vacuum setups. This provides the data necessary to guide and interpret astronomical observations and to model reaction networks in space. [Harold Linnartz]
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Cost-effective catalyst converts CO2 into natural gas
A discovery made in Leiden helps not only to make natural gas from CO2 but also to store renewable energy. Research by Professor Marc Koper and PhD student Jing Shen shows how this process can be implemented in a cost-effective and controllable way. Nature Communications, 2 september 2015.
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Facilities
Our facilities cover:
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Leiden Institute of Chemistry
The Leiden Institute of Chemistry (LIC) is the basis for research and collaborations of the Leiden chemistry groups. Chemistry is the central science enabling a healthy future in a sustainable society. Chemistry researchers at Leiden University take a fundamental approach in finding tailored solutions…
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Thrips resistance in Gladiolus: an eco-metabolomic approach
Breeding for resistance becomes more and more important because we want to reduce the use of pesticides. A fast and cheap alternative can be to make use of morphological or chemical markers.
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Interstellar Catalysts and the PAH universe
Organic molecules in interstellar space are important as they influence the structure of galaxies and star formations. Studying catalytic processes in space allows us to understand how molecular species are formed and chemically evolved in the interstellar medium and solar system objects.
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Unlocking Nature’s Pharmacy from Bogland Species
Development of Natural Resource for New Medicines
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Chemical Biology Lecture: Functional supramolecular systems and materials
Lecture
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In Pursuit of Next-Generation Lipopeptide Antibiotics
Can new variants of daptomycin and the polymyxins be found?
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Multiple star formation: chemistry, physics and coevality
Multiple stars, that is two or more stars composing a gravitationally bound system, are common in the universe.
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Uncovering the ingredients for planet formation
This thesis discusses the physical and chemical processes than influence the composition of forming planets.
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Sizing up protoplanetary disks
This thesis focuses on protoplanetary disks: flattened structures of gas and dust around young stars in which planets are expected to form and grow.
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Analysis of the angucycline biosynthetic gene cluster in Streptomyces sp. QL37 and implications for lugdunomycin production
Streptomyces bacteria are a valuable source of natural products, many of which are used in the clinic or in biotechnology.
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Pair configurations to molecular activity coefficients: PAC-MAC
This thesis provides an overview of the development of the Pair Configuration to Molecular Activity Coefficient (PAC-MAC) model.
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Bioactivity based quality control for Chinese herbal medicine
Can we establish a new quality control system for herbal medicines that is based on bioactivity rather than a few abundant chemicals?
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Hauke Ward
Science
h.ward@cml.leidenuniv.nl | +31 71 527 6808
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Unlocking the chemistry of the heavens
How are the building blocks of life formed?
- Prof Dr André Kessler
- Dr Heiko Vogel
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Control of Western flower thrips through jasmonate-triggered plant immunity
We showed that constitutive and inducible chemical and morphological defenses against Western flower thrips differ between tomato and chrysanthemum plants.
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Non-linear astrochemical kinetics: theory and applications
This Thesis shows discoveries in non-linear astrochemical kinetics as well as a deeper analysis of dark clouds chemistry.
- Prof Dr Caroline Müller
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The astrochemical factory: A solid base for interstellar reactions
In this thesis chemical and physical processes in the ice mantles on interstellar dust grains are studied.
- Prof Dr Nicole van Dam
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The environmental rebound effect: a new paradigm for an old challenge. The case of transport eco-innovation
What is the role of the rebound effect in achieving environmental savings from transport eco-innovation? Are traditional definitions of the rebound effect adequate in the context of transformative innovations and multidimensional environmental issues?
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Assembling anisotropic colloidal building blocks
This PhD-thesis presents a study on micron-sized particles, so-called colloids. By controlling the chemical and physical properties of these particles, such as the interparticle interaction and the particles’ shape, colloids can act as building blocks that self-assembly into larger structures.
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Nano shapes micro : Impacts of metallic nanoparticles on microbial communities
This thesis aimed to investigate the impact of exposure dynamics, relative contributions of ENPs(particle) and ENPs(ion), and dosing regimens on the toxicity of ENPs varying in different physico-chemical properties, on the composition and functioning of soil microbial communities.