575 search results for “covid-19 vaccine” in the Public website
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Can businesses and employers demand proof of vaccination?
Can bars, gyms and travel providers refuse customers who have no proof of vaccination? And can an employer dismiss employees who are not vaccinated? Reports in the Dutch media about travel organisations and a dance instructor who are refusing customers who have not yet been fully vaccinated have sparked…
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Therapeutic vaccine boosts survival rate in cervical cancer patients
A therapeutic vaccine against HPV-16 (type 16 human papillomavirus) improves the survival rate in cervical cancer patients. A new study by ISA Pharmaceuticals B.V. (a Leiden-based biotechnology company) and the Leiden University Medical Center (LUMC) shows that this vaccine produces a more robust response…
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Towards controlled microneedle-mediated intradermal immunization
Traditionally, vaccines are administered intramuscularly using conventional hypodermic needles, which cause pain and distress. Microneedles are very short needles (smaller than 1 mm) that are practically invisible to the naked eye.
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First clinical trial with genetically modified malaria vaccine completed
In an innovative study, Radboudumc and LUMC jointly tested a candidate vaccine based on a genetically weakened malaria parasite. The results of this clinical trial, published in Science Translational Medicine, show that the vaccine is safe and elicits a defense response against a malaria infection.
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COVID-19 Library update
Dear library friends,
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Systems vaccinology: molecular signatures of immunity to Bordetella pertussis
Promotor: G.F.A. Kersten, W. Jiskoot, Co-promotor: B. Metz
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Jeroen Codee
Science
jcodee@chem.leidenuniv.nl | +31 71 527 5037
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Five times more Covid vaccines from a vial with skin injection
Not ten but fifty Covid vaccines from one vial. This is possible if the vaccination is delivered into the skin rather than the muscle, research by internist and infectious disease specialist Anna Roukens from the LUMC has shown. EenVandaag reported on this important discovery, which could have huge…
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Aart Hendriks: Compulsory vaccination is in the interest of public health
Yesterday, the House of Representatives in the Netherlands rejected a motion that would completely rule out an obligation to get vaccinated. Compulsory vaccination in the Netherlands can be considered if public health is at stake. Professor of Health Law Aart Hendriks of Leiden University discussed…
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Bacterial glycomimetics: synthesis and applications
This work has described synthetic strategies towards well-defined structures resembling capsular polysaccharide (CPS) fragments, CPS mimics, teichoic acid (TA) fragments as well as a third-generation ring-closing tandem metathesis (RCM) linker to better exploit the potential of automated synthesis.
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What Accounts for the Variety of National Policy Responses to the COVID-19 Pandemic in Europe?
What Accounts for the Variety of National Policy Responses to the COVID-19 Pandemic in Europe?
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LUMC involved in development of novel drugs to treat and prevent SARS-CoV-2 and other coronaviruses
The Department of Medical Microbiology at Leiden University Medical Center (LUMC) is researching antiviral drugs that could treat and prevent SARS-CoV-2 in various projects. One part of the PanCoroNed project is being led by Martijn van Hemert and involves lab tests into the antiviral effect of molecules…
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Leiden University and LUMC strengthen ties with Janssen pharmaceutical company
Leiden University, the LUMC and Janssen have signed a partnership agreement stating that they will collaborate in different areas, including infectious disease prevention, clinical tests, drug production and e-health. By joining forces, the three partners will be able to provide better, more innovative…
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Development of synthetic procedures towards immunostimulating carbohydrates
Promotor: G.A. van der Marel, Co-Promotor: J.D.C. Codée
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Maria Yazdanbakhsh
Faculteit Geneeskunde
m.yazdanbakhsh@lumc.nl | +31 71 526 5067
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AI versus corona
It’s all hands on deck at the moment to resolve the COVID-19 crisis. Researchers from various disciplines are helping where they can, also from the field of artificial intelligence (AI). AI offers great opportunities both at the frontline of the crisis and in its expected aftermath. Leiden professor…
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Staying Ahead of the Virus
In STAYAHEAD data-intensive approaches are being developed to ”decode the human immunome” with a focus on a global vaccine strategy. They have developed a rapid mass spectrometric test to analyse in real-time large numbers of variants of SARS-CoV-2 and the host immune response, and use these data to…
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COVID-19 Research and Education at Leiden Academic Centre for Drug Research
Since the start of the Corona crisis, several COVID-19 related research and teaching projects were started at LACDR. The computational and teaching activities started right away, as well as a large-scale metabolomics screening program by Thomas Hankemeier’s group. Other experimental activities are still…
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Chemical Synthesis of Fragments of Streptococcal Cell Wall Polysaccharides
This thesis describes the design and synthesis of fragments of various cell wall carbohydrates of the Streptococcus species, including the branched Group B-specific antigen (GBC) of Group B Streptococcus, glycerol phosphate (GroP) modified group A carbohydrate (GAC), and the O-acetylated type 1 capsular…
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Predicting and preventing Covid-19: 1 million euros for corona research
How is it that some covid-19 patients are affected much worse than others? Can we predict beforehand which of them will develop critical symptoms Professor Thomas Hankemeier, together with a diverse consortium of universities, academic hospitals and industrial partners, is looking for the answers to…
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Beryl ter Haar "Special Issue: Covid-19 and Labour Law, A Global Review"
Beryl ter Haar co-editor of the Italian Labour Law e-Journal's
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Rijpma at ICMPD Webinar “Protecting the Right to Protection in times of COVID-19”
On 22 June the International Centre for Migration Policy Development (ICMPD) organised a webinar on the challenges that have arisen for asylum seekers and refugees worldwide as a result of the COVID-19 crisis.
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Zhen Wang
Science
z.wang@lic.leidenuniv.nl | +31 71 527 2727
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Impact of COVID-19: Digital food collectives in Rotterdam
PhD candidate Vincent Walstra reflects on alternative social interactions and mutual aid in the city of Rotterdam during the first wave of the Covid-19 pandemic.
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Why COVID-19 caused a pandemic (whereas other coronaviruses did not)
Epithelial cells play a crucial role in the lungs. PhD student Ying Wang researched the effects of cigarette smoke and viruses such as COVID-19 on these epithelial cells. ‘We hope to reduce the risk of pandemics in the future.’
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Leiden graduate starts petition for visa extension because of Covid-19
Yuven Muniandy (36) from Malaysia recently obtained a PhD from Leiden University. His ‘orientation year’ visa gives him a year to find work in the Netherlands. But with Covid-19, companies have frozen recruitment. Yuven and seven other graduates are asking for a visa extension. He explains why.
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will attend the World Trade Organization Forum on Trade after the COVID-19 pandemic
The CARICOM-MERCOSUR Chamber has confirmed its participation at the ‘Trade Beyond COVID-19: Building Resilience’, a public seminar organized by the World Trade Organization.
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The immune system in action against cervical cancer
In the hunt for a vaccine against cervical cancer, fundamental knowledge about the immune system and organic chemistry have been brought together and have already resulted in a vaccine that is now being tested in clinical trials. Scientists are now working hard on an improved variant.
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COVID-19 update regarding the 2021 ‘Egyptology in the Field’ programme
In accordance with the present travel advice issued by Leiden University and KU Leuven concerning student mobility abroad, it is highly unlikely that the ‘Egyptology in the Field’ programme will be able to take place as normal in Egypt during the 2020-2021 academic year
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Archive
View all our Alumni newsletters below.
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Transvac2
TRANSVAC is a collaborative infrastructure project funded by the European Commission (EC), initially under the 7th Framework Programme (FP7) and currently under Horizon 2020. The project is a joint effort of leading European groups working in the field of vaccine development, and is coordinated by…
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‘The COVID-19 crisis just goes to show how things can go wrong’
Ijeoma Uchegbu is Professor of Pharmacy at University College London (UCL). As a female scientist of colour, she was initially reluctant to play an active role in the university’s diversity policy. Until, that is, she had a radical change of heart: ‘I knew it; I had to become an evangelist.'
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Clashing fundamental rights in KLM labour dispute
Can the KLM reject an applicant for a job as a pilot or stewardess if they refuse to get vaccinated against Covid-19? Or put more broadly: can the employer of a new employee demand that they are vaccinated? Those questions were at the centre of court proceedings brought on Thursday by the Dutch Airline…
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Immune Activation and Tolerance
The Immune Activation and Tolerance group is headed by Dr. Bram Slütter. Vaccination is an experimental, but promising, treatment strategy for atherosclerosis. Previous work has shown that immunization of mice with modified LDL particles can reduce atherosclerotic lesion development, however such vaccines…
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Blog Post | Diplomacy’s Response to the Coronavirus (Part II)
The previous blog post in this series discussed the role of international diplomacy during the coronavirus crisis. This post focuses on diplomacy and its challenges in post-corona times. Specifically, the blog post argues that diplomats will face a range of challenges following the Covid-19 pandemic…
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Key publications
Key publications of the Skin Barrier and Vaccination group.
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Construction and exploration of modular goldnanoparticles for glycan-based immune-interventions of worm infections
Chiodo
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Molecular Signatures of the Evolving Immune Response in Mice following a Bordetella pertussis Infection
Worldwide resurgence of pertussis necessitates the need for improvement of pertussis vaccines and vaccination strategies.
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Overview
Our research is aimed at a smoother and speedier transition from preclinical research to pharmacological interventions, and the delivery of drugs in the human body by use of small molecules and biologics.
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Development of nanoparticulate adjuvants based on aluminium salts
The aim of this thesis was to develop aluminium salt-based nanoparticles that may ultimately be used as adjuvant in human vaccines.
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Hirschman, Accountability in Global Governance
Political Scientist Gisela Hirschmann (Leiden University) asks how international organisations can be compelled to comply with respect human rights. She finds that this is done through ‘pluralist accountability’: external third parties such as courts, NGOs, or regional organisations holding international…
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Synthesis of Ribitol Phosphate based Wall Teichoic acids
Antibiotic resistance, caused by widespread use of antibiotics, leads to bacterial infections that are difficult, if not impossible, to treat and is a major worldwide health concern.
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Oncode Accelerator
Providing each cancer patient with the right treatment remains a challenge. Oncode Accelerator aims to change this by innovating the way we develop cancer treatments, thus ensuring the patient is at the heart of the process. Leiden University, the LUMC and other partners will implement this new way…
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Bioorthogonal deprotection strategy to study T-cell activation and cross- presentation
Cytotoxic T-cells (CTLs) are involved in the clearance of viruses and killing of tumor cells.
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Therapeutic Immunomodulation
The Therapeutic Immunomodulation Group is led by Prof. Johan Kuiper. In this group we aim to identify novel immunologic targets and apply immunotherapy to inhibit or even prevent the development of atherosclerosis.
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Immunotherapy to limit atherosclerosis
Atherosclerosis is a chronic inflammatory disease, and vaccination may be an attractive method to induce long lasting protection against endogenous factors that contribute to the development of atherosclerosis. We have shown that for example vaccination against modified LDL or interleukin-12 limits…
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Conflict resolution by internet platforms
The Covid-19 'infodemic' and conflict resolution by internet platforms.
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Bio Science Park generates thousands of jobs and millions of euros for the Leiden region
The Leiden Bio Science Park (LBSP) is very important not only for the city of Leiden but also for the Leiden region and the Netherlands as a whole. This is the finding of an investigation conducted by the Leiden-Leiderdorp Audit Committee. The large-scale development of the LBSP in recent years has…
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Formulation of Peptide-Based Cancer Vaccines
PhD defence