3,559 search results for “development 26 disease” in the Public website
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Photocleavable activity-based acid glucosylceramidase probes
Lysosomal acid glucosylceramidase (GBA1) is a lysosomal enzyme that degrades glucolipids with its main substrate being glucosylceramide (GlcCer). Defects in the GBA1 gene lead to glycosphingolipidosis Gaucher disease (GD), in which the hydrolysis of GlcCer is impaired and therefore, it accumulates in…
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Bearing with noise: The effects of highway noise on behaviour and development in zebra finches
Anthropogenic noise negatively affects wildlife in a wide range of taxonomic groups.
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Medicine development is hunting magic bullets
Medicines are becoming increasingly precise and innovative, but at the same time increasingly expensive. With their innovations, it is up to universities to increase competition, thus causing prices to drop. This is what newly appointed Professor of Biomolecular Analysis Hubertus Irth argues. His inaugural…
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The development of public speaking anxiety in youth
Does the public speaking anxiety that many youngsters experience originates from specific characteristics in their earlier development?
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The development and prevention of social anxiety in youth
What are the developmental pathways to social anxiety (disorder), the causal processes and maintaining factors? How do these factors interact in the development of social anxiety disorder? How can this knowledge be used to design and implement effective preventive intervention programs for youth?
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NWO awards curiosity-driven research Ariane Briegel with grant
Professor of Ultrastructural Biology Ariane Briegel has received a grant in the NWO Open Competition Domain Science in the XS category. This grant emphatically encourages curiosity-driven and bold research with a maximum of 50,000 euros.
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Control of early plant development by light quality
This thesis describes how different colours of light affect various aspects of the growth and development of Arabidopsis and tomato plants.
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New Perspectives on Desistance Theoretical and Empirical Developments
This book brings together a collection of emergent research that moves the debate on desistance beyond a general consideration of individual and social structural influences.
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Life Cycle Assessment-Based Guidance for development of New Energy Technologies
The development of new environmentally sound technologies is seen as a key route towards achieving sustainability.
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Discovery Leiden nominated for KIJK: Best Tech-idea of 2021
Using artificial intelligence to find new antibiotics. With that, researchers from Leiden University are nominated by magazine KIJK for the Best Tech-idea of 2021. From September 14 onwards people can vote to crown one of the nominees as the winner.
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Law and Society: Governance and Global Development MSc
Are you thinking about studying Law and Society? Learn more and watch the videos.
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Leiden University Medical Center
In the Leiden University Medical Centre (LUMC) we strive to improve health care and the health of people.
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Translational Immuno-Pharmacology
The Translational Immuno-Pharmacology group works on translating the efficacy of anti-infective therapy from preclinical (e.g. in vivo) to clinical, and is led by Rob van Wijk. Infectious diseases, such as tuberculosis, are in constant need of new therapies that work better, faster, and with less risk…
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Modulation of the immune system for treatment of atherosclerosis
Cardiovascular diseases are the primary cause of death in the world with atherosclerosis as primary underlying cause.
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Topic: Stigmatization in patients with chronic health conditions
Imagine that you have a chronic skin condition, characterized by red patches of itchy, scaly skin. You regularly notice people staring at your skin and sense their reluctance to shake your hand. Or imagine that you have Parkinson's Disease, causing your hands to tremble and making it difficult for you…
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Management in Ancient Mexico: Archaeological Heritage and Sustainable Development
This project investigates ancient water management of streams, springs and runoffs on the archaeological site of Monte Albán, Mexico, as a means to contribute with different stakeholders in the development of sustainable solutions to water problems today such as floods and scarcity.
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Development of an Adverse Outcome Pathway (AOP) for metallic nanoparticles
What is the mechanism of action preceding a physiological effects induced by metallic nanoparticles?
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Functions of P38 and ERK kinases in zebrafish early development
Promotor: Prof.dr. H.P. Spaink Co-promotor: Dr. B.E. Snaar
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Development of life cycle assessment for residue-based bioenergy
Promotores: Prof.dr.G.R. de Snoo and Dr. R. Heijungs
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Signalling pathways that control development and antibiotic production in streptomyces
Bacteria are highly complex and diverse organisms that have adapted to survive in ecological niches ranging from the most extreme to the most heterogeneous environments.
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Calcium-dependent regulation of auxin transport in plant development
The plant hormone auxin regulates plant growth and development through polar cell-to-cell transport-generated maxima and minima. PIN FORMED (PIN) auxin efflux carriers determine the direction of this auxin flow through their asymmetric placement on the plasma membrane (PM).
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Report conference ‘EU Criminal Justice Policy and Practice’, 26 – 27 June 2017
Konstantinos Zoumpoulakis, Research Assistant at the Institute of Criminal Law & Criminology, has written a report on this conference
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Dangerous microbes in lower level safety lab? A new technique could make it possible
Researchers need to work in specialized environments when they work with dangerous bacteria and viruses. These microbes spread easily, so only in labs with a high biosafety levels they can be studied. Unfortunately, to look at the microbes properly, expensive microscopes are needed that are not always…
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Graduation ceremony master's programme Cultural Anthropology and Development Sociology
Festival, Graduation Ceremony
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Graduation ceremony master's programme Cultural Anthropology and Development Sociology
Festival, Graduation ceremony
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Figuring rural development: concepts and cases of land use, sustainability and integrative indicators
Promotores: Prof. dr. G.R. (Geert) de Snoo, Dr. E. (Ester) van der Voet
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Teaching and professional development in transnational education in Oman
Antonia Lamers, PhD at ICLON, researched how to create a TNE teaching and learning environment that is in line with the expectations of the British programmes offered to students in Oman.
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Development of visual span in Hebrew and Dutch-speaking prereaders
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Capacity Development of Transnational Law, Asset Recovery and International Investment Arbitration at UI
How can we assist Universitas Indonesia's department of International law to improve their educational and applied research programs on Transnational Law, Asset Recovery and International Investment Arbitration, with an eye on Indonesia’s security and rule of law reform agenda and the needs of the…
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Towards the development of synthetic vaccines against tuberculosis
The research described in this Thesis was aimed at designing and synthesizing nature-inspired compounds as part of TB vaccine discovery.
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Play by the rules? : coordination of EU sustainable development policies and the importance of the politico-legal context
There is an increasing amount of attention on EU and its Member States contributions to implementation of two landmark agreements: the Paris Climate Agreement and the UN Agenda 2030 with Sustainable Development Goals (SDGs). Absent from the current literature is an analysis of the political effect of…
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EMStaD YEMEN: Early Modern State Development in Yemen
How do early modern states organize effective rule in difficult conditions? EMStaD YEMEN focuses on a country that due to its geographical, religious and social complexities is now considered a failed state – Yemen.
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How a Dutchman contributed to the rapid development of Singapore
Frans Stoelinga defended his thesis on 19 November 2020.
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First patients start earning discounts with healthy living
Heart patients who maintain a healthy lifestyle can start earning discounts at shops or for trips out. The Tergooi Hospital is the first in the Netherlands to introduce this unique method that was co-developed by the research group headed by Professor of Health Psychology Andrea Evers and the Leiden…
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NWO grant gives way to more sustainable production of antibiotics
The opportunity to explore a new, exciting research topic. That is how Lennart Schada von Borzyskowski describes his successful application for the NWO XS grant. It comprises 50,000 euros, which the researcher from the Institute of Biology Leiden (IBL) will spend on investigating a more sustainable…
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An Update and Expansion of a Meta-Analysis on Shared Book Reading
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Area studies of the Minor Sustainable Development in four countries
Every January, students of the Minor Sustainable Development have the opportunity to put what they’ve learned over the last few months into practice in a choice of exciting and practical courses called Area Studies. This year, for the first time, there was a choice of four locations: The Netherlands,…
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From stress to success: Vici grant for Dennis Claessen
Why do some bacteria lose their protective cell wall under the influence of stress? Microbiologist Dennis Claessen of the Institute of Biology Leiden receives a Vici grant of 1.5 million euros from the Dutch Research Council (NWO) to investigate this paradoxical feature.
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Inexhaustible source of human heart muscle cells allows strong reduction of animal testing
Researchers at the Leiden University Medical Centre (LUMC) have managed to culture human heart muscle cells on a massive scale. This is an exceptional achievement because it is very difficult to replicate heart muscle cells outside the body. Using a special technique, the researchers have now created…
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‘Unimportant’ plant gene turns out to be essential
Leiden biologists have shown that a gene present in plants, animals and yeasts does play an important role in plants, although for years the gene was considered unimportant. It turns out the gene plays a crucial role in the development of vascular tissue in plants. Publication in Nature Plants on 11…
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Almost 19 million euros for development and study of organs-on-chips
It sounds futuristic, but it is possible: the creation of miniature organs of patients in order to study them and see how diseases develop and can be treated. This is what researchers from the LUMC, Twente University (UT), UMCG, TU Delft and the Hubrecht Institute hope to achieve in the next ten years…
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Bilingualism and Minority Languages in Europe: Current Trends and Developments
This collection considers such issues as the cognitive, linguistic and emotional benefits of speaking two languages, the perceptions, attitudes and issues relating to identity in minority language areas, and the number of grammatical aspects amongst those who speak these minority languages.
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26 Research and Education Grants in 2020 for the Institute of Security and Global Affairs
Whilst 2020 has been an unusual and taxing year for colleagues at the Institute of Security and Global Affairs (ISGA), the Institute nevertheless can look back on an impressive range of successful grant applications during the previous year. This impressive result was achieved on top of excellent results…
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Style, and Uses of Funerary Poetry (9th-12th Cent.) - Poitiers/UCLouvain, 26/27 September and 28/29 November
The University of Poitier and UCLouvain organize two study days on the topic of funerary poetry. The aim of these sessions is to study poetic expressions of mourning in the light of their medium, their style and their usage. The study days will be held respectively in Poitiers (France) on September…
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Developing a vaccine against arteriosclerosis
Cardiovascular diseases are the leading cause of death across the world. Professor Johan Kuiper of Leiden University carries out research to develop a vaccine for arteriosclerosis, which is the main cause of cardiovascular diseases. With the aid of a European research grant of six million euros he is…
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Longevity gene discovered in plants
Harvesting rice from the same field, without planting new rice plants? A discovery may bring this scenario closer. Leiden scientists have discovered a gene that allows annual plants to grow after flowering, instead of dying. Publication on 13 April in Nature Plants.
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Developing drugs with artificial intelligence
Developing new drugs is a difficult process. With the aid of artificial intelligence, Pharmaceutical scientist Xuhan Liu has developed methods that can help make drug design cheaper and faster. PhD defence on 15 February.
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Reducing daily-stress breaking a habit
With this thesis the PhD-candidate aims to enrich the body of evidence concerning the relation between stress and health, and the mediating role of (un)conscious perseverative cognitions, which is captured in the extended perseverative cognition hypothesis.
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Impact of plant hormones on growth and development of actinobacteria
Plants are colonized by an astounding number of microorganisms that can provide different life-support functions, including nutrient acquisition and protection against (a)biotic stresses like drought or pathogen attack.
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A computational tool that will transform bacterial genome analysis
Whether a microbe is beneficial or harmful to a plant can now be predicted with high accuracy thanks to bacLIFE. This bioinformatic tool with an intuitive interface makes it much easier to unlock the secrets of bacterial genomes. A group of Leiden biologists presented it in Nature Communications.