3,568 search results for “development 26 disease” in the Public website
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Sex effects on development of brain structure and executive functions: Greater variance than mean effects
This study is the first to directly relate brain development to sex differences and school performance. The results debunk the myth that brain development is slower in boys.
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Role of leukocytes in metastasis formation in a zebrafish
How do macrophages and neutrophils contribute to metastatic onset?
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Understanding plant transgenesis
How is Pol θ responsible for T-DNA integration, and how do other DNA double-strand break repair pathways interact with Pol θ? How may we manipulate T-DNA integration to stimulate error-free integration at a predetermined genomic site?
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Executive deficits, behavioural problems and early reading development
This study tests whether behavioural problems at a young age are related to early reading and mathematics development.
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BEAT-COVID team discovers sugar-coated antibodies that predict disease progression
At the start of the COVID-19 pandemic, researchers from 15 departments at Leiden University Medical Center (LUMC) realised they could do more for patients if they joined forces. This is how the BEAT-COVID group has been able to rapidly gain knowledge about COVID-19, the role of the immune system and…
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Nutrient-rich water is heaven for disease-spreading mosquitoes
When mosquito eggs hatch in nutrient-rich water, the mosquitoes are larger and they can also fly further. That is the first conclusion of a study from by the Netherlands Centre for One Health (NCOH) by PhD-student Sam Boerlijst.
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Linking aboveground-belowground interactions and plant-soil feedback to improve pest control and sustainability in greenhouse cut-flowers
We examine how soil inoculation influences aboveground organisms (i) directly, and indirectly via (ii) its effects on plant chemistry or volatile emission, or via (iii) mediating the effects of belowground pathogens on aboveground organisms via the shared plant.
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Leiden iGEM team wants to build a kit to diagnose infectious diseases
Fourteen bachelor’s and master’s students are representing Leiden University in this year’s International Genetically Engineered Machine competition (iGEM). Their plan: to create a kit that can be used to quickly identify infectious diseases in case of an outbreak.
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Cultural Anthropology and Development Sociology
Vulnerability and the associated levels of social resilience is what fascinates the researchers at the Institute of Cultural Anthropology and Development Sociology. What links a Japanese fisherman after the tsunami at Fukushima with a Ghanaian goldminer in an increasingly industrialised work environment?…
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Mood variability during adolescent development and its relation to sleep and brain development
During adolescence, mood disorder onset peaks. Mood variability is associated with negative mental health outcomes, so understanding biological factors that might be associated with mood variability, such as sleep and structural brain development, could elucidate the mechanisms underlying mood and anxiety…
- IBL Spotlight - Development & Disease
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Better treatment of skin diseases thanks to NWA grant of 11.7 million euros
Patients with skin diseases such as eczema and psoriasis, sometimes spend a lifetime searching for the right medication. To help these patients faster and better, scientists across the country are joining forces. The Next Generation ImmunoDermatology (NGID) project, with LACDR professor Robert Rissmann…
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From bed to bench and back to the future
Retrospection over the last 40 years the most important changes in care and research, where transparency accountability and guidelines became leading. On Huntington’s disease and cerebrovascular disorders the most important changes are illustrated.
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R-ELEVATION
How do plant defense genes get activated?
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Data mining and algorithm development
Due to the modern techniques of combinatorial chemistry and high-throughput screening, data on the biological activity of many millions of compounds is known. However, it is still very difficult to transfer this data into knowledge: if we know that compounds A and B bind to a certain protein with high…
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Challenge grant for research into autoreactive B cells in cardiovascular disease
At the division of BioTherapeutics, Amanda Foks, Bram Slütter and Ilze Bot have obtained a €4 million research grant from the HORIZON 2022 EIC Pathfinder Challenge “Cardiogenomics”, entitled “B-specific: B-cell related gene and protein markers with prognostic and therapeutic value for CVD”.
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Research
Central elements in the research activities of all programme group members are: attachment, sensitive caregiving, and prevention and intervention.
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Agrobacterium-mediated protein therapy for genome editing
Is translocation of nucleases possible via Agrobacterium T4SS and is it efficient enough for mutagenesis?
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cross-contextual media landscape: Children’s digital media use and their social development
For this project we delve into children's digital media use during the transition from kindergarten to group 3 and investigate its impact on their social development.
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redesigning a program using characteristics of effective instructional development
In this research project characteristics of effective instructional development were identified that are appealing to medical teachers and relevant for medical education.
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Peace, Justice and Development (Advanced LL.M.)
The specialization Peace, Justice and Development at Leiden University examines the legislation that governs international relations in a global society.
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Polymers in the Liver: Metabolism and Regulation
Metabolic diseases are a burden on the European population and health care system. It is increasingly recognised that individual differences with respect to history, lifestyle, and genetic make-up affect disease progression and treatment response. A Systems Medicine approach, based on computational…
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Professional development of VET teachers in the context of work placement
This project focuses on vocational teachers’ professional development in work placement. Teachers’ learning motivation, learning experience and learning outcomes within work placement will be explored in depth.
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Evolution and development of bitterling fish
How has early development in R. ocellatus been modified as a result of its parasitic embryonic lifestyle?
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Applied Neuroscience in Human Development (MSc)
Are you interested in the neurocognitive and biological roots of learning, behaviour and emotions in children? If so, the programme in Applied Neuroscience in Human Development might be the specialisation you are looking for.
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TARGETBIO: Transmission of Antimicrobial Resistance Genes and Engineered DNA from Transgenic Biosystems in Nature
This project aims to assess the risk of spread of antimicrobial resistance genes in the environment derived from currently used synthetic biology approaches in the field of drug discovery.
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The development of children in foster care
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Teacher identity and teacher’s professional development in an intercultural context
The present project aims to provide valuable insights for the professional development of international teachers, and also for improving the quality of foreign language education.
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Career and development - Working at Leiden University
If you have the ambition to continuously develop and grow in your work, then Leiden University is an attractive employer for you.
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Education
The programme group Parenting, Child Care and Development carries out general courses within the field of Education and Child Studies and specialised courses within the field of Child and Family Science.
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Digital Media in Human Development (MSc)
Digital media are everywhere and are therefore a major part of our lives and the lives of our children. The new specialisation in Digital Media in Human Development focuses on the opportunities and challenges of digital media in child rearing and education.
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Polyfluorinated bis-styrylbenzenes as amyloid-beta plaque binding ligands
Detection of cerebral beta-amyloid (Abeta) by targeted contrast agents remains of great interest to aid the in vivo diagnosis of Alzheimer's disease (AD). Bis-styrylbenzenes have been previously reported as potential Abeta imaging agents.
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Comorbidities, complications and treatment of childhood obesity
Childhood obesity is an increasing health issue. In the first part of this thesis comorbidities in children with obesity were studied, concerning the diagnostic process and dosing regimens.
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The important role of stratum corneum lipids for the cutaneous barrier function
The skin protects the body from unwanted influences from the environment as well as excessive water loss. The barrier function of the skin is located in the stratum corneum (SC).
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Protein arginine methyltransferases as modulators of lipid metabolism and inflammation and the relevance for atherosclerosis
Acute cardiovascular clinical events such as myocardial infarction and cerebral stroke represent the major cause of death in Western societies. These pathologies are primarily resulting from atherosclerosis, a progressive condition characterized by the accumulation of lipids, immune cells, and fibrous…
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Single-cell immune profiling of atherosclerosis: from omics to therapeutics
Acute cardiovascular syndromes, including myocardial infarction or stroke, are the principal cause of death in the Western society. The main underlying pathology of cardiovascular diseases is atherosclerosis, which is caused by the accumulation of lipids and inflammatory cells in the vessel wall, in…
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How e-coaching helps people with chronic kidney disease to live more healthily
An e-coaching programme helps people with chronic kidney disease, particularly in areas that patients themselves want to work on. ‘A healthy lifestyle is important for patients with kidney disease: it can slow down the loss of kidney function and there will be fewer complications,’ Katja Cardol explains…
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Development of thermostable lyophilized inactivated polio vaccine
The aim of current study was to develop a dried inactivated polio vaccine (IPV) formulation with minimal loss during the drying process and improved stability when compared with the conventional liquid IPV.
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Leiden Consortium on Individual Development (L-CID)
Why are not all children equally responsive to variations in the social environment?
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Cell Wall Dynamics in Aspergillus niger
This functional genomics project aims at understanding the biology of the underlying mycelium differentiation and autolysis processes in much more detail.
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Cell architecture and pathways for parallel secretion in the filamentous fungus Aspergillus niger
Research aims: Identification of key genes involved in programming the cellular architecture of A. niger & Genetic engineering of A. niger in order to improve its secretory capacities and rheological behavior under industrial fermentation conditions.
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Nose of E. coli zips open and shut
PhD student Wen Yang discovered how certain cell receptors in E. coli bacteria signal 'smells'. With the use of ice-cold electron microscopy microbiologists from Leiden gain more insight into how bacteria respond to their environment. Publication in mBio.
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Cultural Anthropology and Development Sociology (MSc)
Discover the Master's programme in Cultural Anthropology and Development Sociology at Leiden University. Undertake independent ethnographic research and contribute to society.
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International development finance: challenges and opportunities
Don Scott De Amicis will give the sixth Hazelhoff Guest Lecture on international development finance: challenges and opportunities.
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How the ‘English disease’ turned out to be not so very English after all
A vitamin D deficiency is often associated with smoggy English industrial cities during the Industrial Revolution, but research carried out on skeletons now suggests that the ‘English disease’ was also prevalent in rural areas of the Netherlands. Doctoral defence on 29 January.
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Short intensive session on educational development
Didactics
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Longitudinal brain development (Brain Time study)
How is structural and functional brain development related to behavioral change in cognitive-control, impulse regulation, and socio-emotional functioning?
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Kim Stroet
Faculteit der Sociale Wetenschappen
k.f.a.stroet@fsw.leidenuniv.nl | +31 71 527 3955
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Alice Kubo
Afrika-Studiecentrum
a.m.kubo@asc.leidenuniv.nl | +31 71 527 2727
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Esther Mertens
Faculteit der Sociale Wetenschappen
e.c.a.mertens@fsw.leidenuniv.nl | +31 71 527 2727