1,195 search results for “diagnostics and treatment” in the Public website
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Blended Care for Adolescents with Social Anxiety
Is blended care a feasible and effective treatment method for social anxiety in adolescence?
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A good start: Early prevention of anti-social behavior
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Systems pharmacology of human neuroendocrine disease entities
An important hormone excreting gland in the human body is the pituitary
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Evolutionary adaptability of β-lactamase: a study of inhibitor susceptibility in various model systems
β-Lactamases are enzymes that can break down β-lactam substrates, such as antibiotics, preventing the use of these antibiotics for the treatment of various infectious diseases. However, some compounds, β-lactamase inhibitors, can block these enzymes allowing for possible treatments using a combination…
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Routine Outcome Monitoring and Feedback in Psychological Therapies
Kim de Jong, Jaime Delgadillo, and Michael Barkham offer valuable insights in their book 'Routine Outcome Monitoring and Feedback in Psychological Therapies' on how therapists and trainees can use feedback to inform treatment decisions and, ultimately, enhance patient outcomes.
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The Function of Toll-like receptor 2 in Infection and Inflammation
The function of TLRs in innate immunity has aroused worldwide attention soon after its discovery. Because of the broad functions of TLR2 in innate immunity, the drive for the development of TLR2-targeted vaccines or therapeutic treatments has accelerated in the last decades.
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Boosting the host immune system to fight tuberculosis
New drugs for use as tuberculosis (TB) treatment are needed due to the constrains of classical antibiotics against TB and the rise of antibiotic-resistant strains, making TB a harder and harder disease to treat.
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Targeted Therapy for Triple-Negative Breast Cancer
The research described in this thesis focused on identifying novel drug targets and synergistic combinations for triple-negative breast cancer (TNBC), a virulent subtype of breast cancer with a dismal prognosis and limited therapeutic options.
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Refining individualized treatment in older patients with breast cancer
PhD defence
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Strategies to optimise the treatment of community-acquired pneumonia
PhD defence
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Patient readiness for shared decision making about treatment
PhD defence
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Updates in Molecular Diagnosis and Targeted Treatment of Thyroid Neoplasia
PhD defence
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Optimizing antiseizure medication treatment in glioma patients with epilepsy
PhD defence
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Quality assessment and multi modalty in gastric cancer treatment
PhD defence
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Towards personalized treatment for high risk endometrial cancer
PhD defence
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Overview
The Division of Systems Pharmacology and Pharmacy (SPP) aims to develop precision medicine approaches to characterise and predict variation in treatment response and enhance translational drug development strategies.
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‘It’s a real balancing act for doctors at gender clinics’
Do young people who want to change gender have the unconditional right to medical treatment? Pediatric Endocrinologist Martine de Vries, who is also Professor of Medical Ethics, treats transgender children and adolescents. She will discuss this in her ‘Pride Talk’ on 18 September.
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Data Science
The ability to collect and interpret huge quantities of data has become indispensable to society and academia. Leiden University is a knowledge and expertise centre for data science that places the emphasis on interdisciplinary collaboration and innovation.
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Medical Delta professor Lioe-Fee de Geus-Oei: 'We work together for the patient'
Professor of Radiology Lioe-Fee de Geus-Oei was already a professor at LUMC and the University of Twente. As Medical Delta professor, she has now also been appointed at Delft University of Technology. 'Talking with people from other disciplines always makes me immensely humble, because they look at…
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Annemarie Drahmann on new European regulations for stallholders
There is much unrest among local stallholders in Utrecht. Owners who for decades had a permanent pitch for their stall are no longer guaranteed this due to new European regulations. So no more benefits for the current stallholders which is causing them great uncertainty and frustration.
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Admission requirements
Is this the master's specialisation of your choice? Please read here about the admissibility for this programme.
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Admission requirements
Is this the master's specialisation of your choice? Please read here about the admissibility for this programme.
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Admission requirements
Is this the master's specialisation of your choice? Please read here about the admissibility for this programme.
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Admission requirements
Is this the master's specialisation of your choice? Please read here about the admissibility for this programme.
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Admission requirements
Is this the master's specialisation of your choice? Please read here about the admissibility for this programme.
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Research
The Institute of Psychology is responsible for innovative and interdisciplinary research and education within psychology and related disciplines. It focuses primarily on four broad areas: Health and Wellbeing; Development and Learning; Socio-Cognitive-Affective Decision-making and Advanced Behavioural…
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Research
Research lines within the Pharmacy group:
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Research ecosystem
The chain that supplies patients with new medicines consists of various complex links: from fundamental research to clinical tests and production. This entire chain is represented in Leiden. Leiden University, the Leiden University Medical Center (LUMC), and the companies on the Leiden Bio Science Park…
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UM Cure 2020: New therapies for uveal melanoma
Can we bring novel treatment options to the clinic for UM patients with liver metastases?
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Multifocal approach of wrist related injuries
PhD defence
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Biomedical Imaging
The rapid advances in imaging technology enable to see inside the body with ever increasing detail.
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Novel chemical tools for target validation in neuroinflammation
In what way can new tools and techniques be used to develop drug candidates for the treatment of neurological disorders?
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Prediction of human gut (colon cancer) target site concentrations and PKPD relationships
The advanced insights obtained for the CNS PBPK model development are currently used to develop advanced mathematical models for drug distribution prediction in other body tissues protected by barriers, such as the gut. The gut PBPK model will be linked to drug effects for treatment of colon cancer.
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Innovative (electro-driven) sample preparation tools for metabolomics study of muscle aging
This thesis focuses on the development of sample-preparation methods for small amounts of samples and applying the developed methods to muscle tissues to investigate the mechanisms involved in sarcopenia.
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Immunity, Infection and Tolerance
The LUMC has a longstanding tradition researching the role of the immune system in infectious diseases, transplantation and auto-immune diseases.
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Health Data Science
Health research, medical practice and consequently the whole population is increasingly affected by digitization, data science and AI.
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Evidence-based treatment of central serous chorioretinopathy
PhD defence
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modeling of pharmacokinetics and tumor dynamics to guide anti-cancer treatment
PhD defence
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New collaboration aims to predict cancer survival
Predicting cancer survival with machine learning, that is the aim of a new collaboration between the Mathematical Institute, the European Organisation for Research and Treatment of Cancer (EORTC) in Brussels and Leiden University Medical Center. The focus of this project is to characterise the model…
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Vincent Delhomme and Carina Van Os on 'The European Health Union'
On 1 and 2 December 2022, Vincent Delhomme and Carina van Os participated (Europe Institute) in the workshop ‘The European Health Union - Setup, challenges and global outlook’, held at the Max Planck Institute for Comparative Public Law and International Law in Heidelberg. Vincent had the opportunity…
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The rights of the developing child
As children learn, develop and acquire more skills, their legal position also changes. Professor of Children’s Rights Ton Liefaard works closely together with Leiden social sciences researchers to shed light on these growing capacities and their implications for our legal system. ‘Our ideas about children’s…
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Healthy ageing
The elderly accept may minor discomforts like stiffer muscles and getting tired more quickly, but they do want to go to their children's birthdays independently. Preventive elderly care helps people with that. The goal is to let people grow old while maintaining their self-reliance and independence…
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Eiko Fried in APS on Open Science
Although open science reforms have contributed to a more rigorous and robust psychological science, there is still much to improve. In Association for Psychological Science (APS), Eiko Fried points out two norms that open science reforms may have overlooked so far: communalism and universalism. 'Incorporating…
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Development of new antibiotics from plant-originated products
Utilization of plant-originated products as new antibiotics
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Light-activatable ruthenium-based anticancer prodrugs
Can light-activatable ruthenium compounds be used as a more selective anticancer treatment?
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Workshops & Demo's
During the Leiden Science Family Day, you can take part in various workshops. You can also watch various demonstrations. Where will you go?
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Determining the kinetic profile of ENT1 inhibitors
Supervisor: Anna Vlachodimou
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A comparative perspective on perceived legitimacy: evaluating authorities in democratic and no-democratic contexts
Does the political context (e.g., democracy vs. authoritarianism) influence what makes people perceive authorities as legitimate?
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Leiden Academic Centre for Drug Research
Drug development is a complex process in which many parties work together. Every day, the researchers at LACDR devote their energies to developing drugs that are new, better, more efficient and easier to produce. And thus to the millions of patients who know all too well why this research in Leiden…
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Leiden Early Drug Discovery & Development
Despite recent advances in medicine, many devastating disorders like cancer and cardiovascular, neurodegenerative and infectious diseases still lack effective treatments. In order to address this challenge, we, as scientists from Leiden University, joined hands in the LED3 network. LED3, for Leiden…