Nadine Raaphorst wrote an chapter for The Oxford Handbook of Administrative Justice about how two notions of fairness are studied in street-level bureaucracy literature and about the factors that influence how bureaucrats behave in this regard.

Mohamed Tleis was born in Lebanon and studied there up to and including university. It was not an easy path because Tleis has to cope with a number of limitations: he has problems with both hearing and vision.

Peter Rodrigues, Professor of Immigration Law, has been appointed as a deputy member of the Netherlands Institute for Human Rights for a period of eighteen months.

The chairman of an allotment garden association in the Dutch town of Helmond has come under fire as its regulations contain a controversial rule that a maximum of five plots can be rented by one single nationality.

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The more we learn about a (neuro-)psychological or physical disorder and the related behavioral factors, the better we can not only identify them, but also treat them. It is therefore important that recent insights about (neuro-)psychological problems and related behavioral factors are incorporated…

Female workers at Tesco Stores, a chain of supermarkets in the UK, brought a case to the European Court of Justice claiming they received unequal pay for doing work of equal value to that of their male colleagues.

About nine million people worldwide contract tuberculosis each year. Research into new treatment for this disease has received fresh stimulus with more efficient techniques and a new understanding of how the tuberculosis bacteria works.

In this article, James Shires and Tatiana Tropina, assistant professors at the Institute of Security and Global Affairs, map the relationship between gender equality and cybersecurity governance as a component of good security sector governance (SSG). Here, it highlights the way in which cybersecurity…

Promotores: B. van de Water; P. Hogendoorn; J. Bovée Co-Promotor: E.H.J. Danen

Treatment and care for cancer patients is becoming increasingly advanced. For example, surgeons can now perform operations with much greater precision, and therapeutic vaccines are being developed to prompt the patient’s immune system to fight cancer. Work is also being done on better early diagnostics,…

The aim of this project is to investigate the (cost)effectiveness of two innovative forms of trauma-focused therapy for patients with childhood abuse related PTSD. The ultimate goal is to improve quality of care and contribute to treatment innovation for this severely ill target population.

In case of serious illness, treatment in the Intensive Care Unit (IC) may be necessary. Intensive care treatments has improved over the years and more and more seriously ill patients are surviving admission to the ICU. This favorable development however has a downside since long-term consequences of…

Can drugs that target host signaling pathways be used to eradicate antibiotic-resistant bacteria?

Childhood obesity is an increasing health issue. In the first part of this thesis comorbidities in children with obesity were studied, concerning the diagnostic process and dosing regimens.

People who have taken antibiotics in the past three months pay more attention to negative facial expressions, according to research by postdoc Katerina Johnson and assistant professor Laura Steenbergen. This may explain how antibiotics increase the risk of developing depression.

Can a newly developed, app-based, personalized maintenance program enhance the effectiveness of the exposure-based one-session-treatment for children with a specific phobia?

Role models are key to inspiring the next generation. Fifteen female professors therefore celebrated International Women's Day with girls aged between 12 and 16. Because although the number of women at the (academic) top is increasing, we're not there yet.

Sepsis is a life-threatening condition caused by a dysregulated host response to infection, it is associated with significant morbidity, mortality, and with a high financial burden on global healthcare systems. Bacterial infections are the primary cause of sepsis, but the growing prevalence of antimicrobial…

Promotors: C.A.J. Knibbe, Anthonius de Boer, Co-promotor: M.M.J. van der Vorst

Imagine how much time, money and discomfort it would save: a personalised treatment for each individual patient. Precision medicine like this is coming ever closer, thanks in part to Elise Dusseldorp’s algorithms. They retrieve a wealth of information from research data.

If a new method has been developed to recognize and treat a (neuro-)psychological disorder or related behavioral factors, it cannot yet be used directly in clinical practice. First, the method should be evaluated, preferably in randomized controlled trials.

Can we exploit the cell death machinery of the host to develop new host-directed anti-TB treatments?

Fungal infections pose a significant threat to individuals with compromised immune systems and despite advancements in diagnosis and treatment, they continue to jeopardize patient’s health.

Previous research has found important inter-individual differences in the pharmacokinetics (PK) of morphine in special populations such as children, the morbidly obese or the critically ill.

The aim of this thesis was to develop novel treatment strategies for different types of eye melanoma utilizing zebrafish models. We first establish orthotopic and ectopic xenograft models for uveal and conjunctival melanoma by engraftment of the immortalized cells derived from these tumors into zebrafish…

Cardiovascular diseases are the primary cause of death in the world with atherosclerosis as primary underlying cause.

There is much unrest among local stallholders in Utrecht. Owners who for decades had a permanent pitch for their stall are no longer guaranteed this due to new European regulations. So no more benefits for the current stallholders which is causing them great uncertainty and frustration.

The spindle-assembly checkpoint (SAC) is a safety mechanism which secures accurate chromosome segregation during mitosis.

This thesis represents a comprehensive investigation into the control of cancer stemness and metastatic initiation using a combination of advanced zebrafish xenograft models and in vitro assays.

PhD defence

PhD defence

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Social Policy is increasingly incorporated as a subject of European law. The Social Dialogue with labour and management organisations leads to agreements that can be transformed into Directives of the Council

This thesis focuses on using liposomes in two different treatment strategies; vaccination (or immunotherapy) and delivery of a small molecule, and in two different disease models; cancer and atherosclerosis.

How does stress influence cognitive performance? What is the role of selective attention to threatening information in this effect? Could we prevent stress-induced decline of cognitive performance with pharmacological interventions? Could we use resting state theta/beta ratio as a biomarker for cognitive…

The disease acute myeloid leukemia (AML) is characterized by fast progression and low survival rates.

The aim of this project is to explore the use of statistical interaction models to quantify cross-omics and omics-drug interactions in large-scale clinical and experimental datasets

This is a study of Plateau Shimakonde, a sub-dialect of the Makonde language which is spoken on the Makonde Plateau in northern Mozambique.

Rutsel Martha, former Minister of Justice of the Dutch Antilles, former General Counsel of Interpol and alumnus of Universiteit Leiden, elaborated on the position of states and intergovernmental organizations (IGOs) in international financial law.

‘From formal equality to transformative equality: the road to “other law” according to Holtmaat?’

How can we manipulate the biotic and abiotic environment to increase thrips resistance in tomato and chrysanthemum? More specifically we ask: How can plant secondary metabolites that are not soluble in water be delivered to plants in seed coating or root dipping treatment? Can bacteria be used to…

In a lawsuit concerning the upcoming Dutch elections, the Partij voor de Dieren (Party for the Animals) is claiming that everyone should be able to cast a postal vote. Is it a form of discrimination that everyone above the age of 70 is allowed to cast their vote by post, but people who are younger and…

Lipid signaling is an essential biological event/process in a plethora of pathophysiological conditions. The underlying idea of this thesis is that many of the roles and the complex interplay of the individual signaling lipids in inflammatory processes and related conditions in health and disease is…

Which intervention technique is more effective in reducing public speaking anxiety in children aged 9 – 12 years, exposure or restructuring cognitions?

How can the Indonesian National Ombudsman make the transition from autonomous to responsive justice in view of the day-to-day challenges it is faced with?

Which challenges exist for girls to effectuate their right to education and specifically getting access to education?

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