Promotor: Prof.dr. W.J.G.M. Peijnenburg, Co-promotor: Dr. ing. M.G. Vijver

A critical look at the impact assessment modelling of metals in Life Cycle Impact Assessment and improvement options.

Promotores: Prof.dr. W.J.G.M. Peijnenburg & Dr. M.G. Vijver

Quantum critical metals at vanishing fermion flavor number.

Promotor: G. J. Kroes

In this thesis, we have used numerical approaches to study the effects of translational symmetry breaking on strange metallic systems as realised by the holographic duality⁠.

How to improve the method in quantifying the combined effects of metal-based chemicals?

Accumulation of metals in economy and environment and its associated risks, within the Netherlands and the EU.

Metal-containing molecules combine geometrical features and a reactivity that are inherently different from that of organic molecules. My research focuses on light-activatable metal-based anticancer drugs and metal-functionalized liposomes. Light is a very selective way to activate photosensitive drugs…

Can we provide the Dutch government with an integrative framework, wherein the various policies can be placed and the need for further measures can be identified?

Central in coordination and organometallic chemistry is the synthesis of new chelating ligands, the synthesis and characterization of metal complexes with these ligands, and the study of their properties. An important goal in my research is to create understanding of the relation between the structures…

Galaxies are environments where gas coalesces, cools, and is converted into stars. However, it remains unclear the exact mechanisms through which galaxies acquire, redistribute and lose their gas.

The current production of a number of critical metals is insufficient for the large-scale transition to electric vehicles. This is the conclusion of a report by environmental scientist Benjamin Sprecher and organisations Copper8 and Metabolic. As a solution, they advocate more electric car-sharing,…

The aim is to discover where differently shaped metal nanoparticles distributes in Danio rerio, linking the distribution with genomic responses and so come up with a Mode of Action.

Coordination chemistry is the chemistry of metal atoms

Lecture, Tuesday Talks: Science Insights

The dissociative chemisorption of a molecule on a transition metal surface represents a rate-limiting step in many heterogeneously catalyzed processes, whereby most chemicals are made. In spite of the importance of this reaction, an accurate first principles approach to modeling it does not yet exist.…

In the last decade, the redox interconversion between metal thiolate and disulfide compounds has been extensively investigated for copper, but not for other transition metal ions.

In-use stocks of products can be considered as intermediaries between human needs and the physical world.

We review the state-of-the-art in the theory of dissociative chemisorption (DC) of small gas phase molecules on metal surfaces, which is important to modeling heterogeneous catalysis for practical reasons, and for achieving an understanding of the wealth of experimental information that exists for this…

M.T.M. Koper, Co-promotor: D.G.H. Hetterscheid

What is the mechanism of action preceding a physiological effects induced by metallic nanoparticles?

Promotores: Prof.dr. J. Schaye & Prof.dr. C. Steidel (California Institute of Technology)

Metals surfaces form a group of effective catalysts for the reaction of small molecules such as hydrogen (H2).

Promotores: Prof.dr. W.J.G.M. Peijnenburg & Dr. M.G. Vijver

It is estimated that approximately 30% of all proteins require a metal to function. Investigating the relationship between metal-binding and peptide/protein folding allows us to uncover fundamental rules for creating metallo-peptides and proteins, which in turn leads to the creation of new structures,…

This thesis aimed to investigate the impact of exposure dynamics, relative contributions of ENPs(particle) and ENPs(ion), and dosing regimens on the toxicity of ENPs varying in different physico-chemical properties, on the composition and functioning of soil microbial communities.

The interest of this thesis lies in spin transport in normal metals and superconducting half-metallic junctions.

This thesis focuses on the synthesis, characterization and performance towards CO2 electroreduction of mono and bi-metallic particles based on p-block metals

Fundamental understanding of molecular reactions on metal surfaces is important for improving heterogeneous catalysis.

The rapidly increasing commercial application of metallic nanoparticles within products will inevitably enhance the amount of NPs being released into soil.

The research described in this thesis focused on the preparation of S/N functionalized carbene ligands and their transition metal complexes, and the exploration of their application as electrocatalysts for proton reduction.

Promotor: Prof.dr. G.J. Kroes

Promotor: Prof.dr. G.R. de Snoo, Co-promotores: Dr. ing. M.G. Vijver, J.P.M. Vink

This research focuses on the (Quantum) Dynamics (QD) of the reactive scattering of H2 from metal surfaces.

The research presented in this thesis explores the chemotherapeutic potential of metal-based compounds as chemotherapy agents, with an initial focus on the synthesis and DNA interaction studies of platinum and palladium compounds utilizing the [Pt(bapbpy)]2+ scaffold. The study identifies intercalation…

This was the question Leiden researchers from the Institute of Environmental Sciences CML posed in an article published last week in the journal Resources, Conservation, Recycling

Describe and identify what dosimetry parameters are of importance to interpret dose-response relationships (eg., mortality, sub-lethal, growth or reproduction inhabitation, DNA damage and reactive oxygen species, etc. ) for metal-based nanoparticles? How to develop quantitative models that enable to…

Mathilde Mechling defended her thesis on 28 january 2020.

On 22 January 2018, the Massive Open Online Course ’A Circular Economy of Metals: Towards a Sustainable Societal Metabolism’ kicks off. This course is developed and taught by associate professor Ester van der Voet.

Assessing the risks of engineered nanomaterials (ENMs) solely on the basis of experimental assays is time-consuming, resource intensive, and constrained by ethical considerations (such as the principles of the 3Rs of animal testing). The adoption of computational toxicology in this field is a high p…

A plant that takes metal from the ground all by itself: a natural way to mine or to clean the soil. PhD student Roderick Bouman (Hortus Botanicus Leiden) described a new plant species from Sabah, Borneo, which can be used to extract nickel. In an open access article in Botanical studies, he and the…

Researchers from the THEOR CHEM group at Leiden University strive to set new benchmarks in the accuracy of the prediction of interaction energies between molecules and metal surfaces.

Friday 30 January 2015 were the final presentations of the last course of the Minor Sustainable Development.

Storing energy is one of the biggest challenges in the energy transition. Hydrogen could be a solution. Chemist Daan den Boer is researching how to make the chemical reaction needed to store energy in hydrogen as cheap and efficient as possible.

In 2017, in an ordinary field, two brothers from Brabant discovered more than 100 ancient coins. The Leiden historian who examined the coins concluded that they constituted a genuine Roman treasure. Here follows a reconstruction in three acts.

Although nanoparticles are extensively used in various applications like consumer products and have most probably entered the environment, little is known about the effects of these particles on living organisms.