279 search results for “vaccination” in the Public website
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Unraveling cross-presentation pathways using a chemical biology approach
Is it possible for sugar patterns on cells to activate the immune system to combat cancer?
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RESTORING T-CELL HOMEOSTASIS BY IN VIVO MANIPULATION OF DENDRITIC CELLS
The loss of T-cell homeostasis and tolerance towards self-antigens is the underlying cause of autoimmune and inflammatory diseases like atherosclerosis, rheumatoid arthritis or type I diabetes. Traditionally, the treatment of these diseases consisted on systemic immune suppression, which can entail…
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Student projects
Bachelor and Master students of all chemistry related studies are more than welcome to take part in our research activities. We have projects on design and synthesis of biologically relevant compounds within an ongoing research project. Supervision, following the apprentice/teacher model, is one of…
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Key publications
Key publications of the Barz Lab
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Bioorthogonal Antigens as Tool for Investigation of Antigen Processing and Presentation
In order to be able to develop effective medicine and treatments to prevent or cure autoimmune diseases or cancer we need to understand the mechanisms how they arise and what drives their course.Unravelling the fundamental molecular mechanisms influencing the onset and course of diseases such as allergies,…
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Archive
View all our Alumni newsletters below.
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Immunity, Infection and Tolerance
Our immune system protects us against disease, but every now and then, something goes wrong: an enemy invades our bodies or our immune system attacks our own cells and we become ill. Doctors and researchers at the Leiden University Medical Center (LUMC) want to be able to manipulate the immune system…
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The most read stories of 2021 from Leiden University
Research into depression in children, Leiden alumni in the Dutch House of Representatives and an exceptional achievement by one of our students: what do this topics have in common? They are among our most read stories of 2021.
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Resetting the immune system to cure diabetes and rheumatism
In autoimmune diseases such as rheumatism and diabetes the immune system attacks autologous proteins. Leiden researchers are trying to discover how this comes about.
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Science Experience Tours
During the Leiden Science Family Day, you will visit places that are normally closed to the public: go backstage at the Faculty of Science!
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Novel immunomodulatory drugs for tuberculosis treatment
Can drugs that target host signaling pathways be used to eradicate antibiotic-resistant bacteria?
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Alternatives to animal experiments: Replacement, Reduction and Refinement
We aim to conduct as few animal experiments as possible. We are continually exploring methods to Replace, Reduce, and Refine animal experiments, commonly referred to as the three Rs. Additionally, we assess each study to ensure the implementation of the 3Rs has been maximised. The Animal Welfare Body…
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Why Leiden University?
We are committed to provide you with meaningful, rigorous and quality graduate experiences in a personalized environment with a cutting edge research infrastructure and internationally renowned supervisors.
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Clashing fundamental rights in KLM labour dispute
Can the KLM reject an applicant for a job as a pilot or stewardess if they refuse to get vaccinated against Covid-19? Or put more broadly: can the employer of a new employee demand that they are vaccinated? Those questions were at the centre of court proceedings brought on Thursday by the Dutch Airline…
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Leiden students develop highly contagious card game
Infecting each other with viruses and bacteria while protecting yourself with medicines and vaccinations. Sounds like a fun evening, right? Master students Life Science & Technology Rafael Jezior and Dennis de Beeld certainly think so. Together, they developed ImmunoWars: an exciting card game based…
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Malaria researchers from all parts of the world in Leiden
Researchers from all parts of the world will be in Leiden from 2 to 4 May for a major malaria conference. The Leiden University Medical Center (LUMC) is organising a two-day workshop on how vaccines can be tested safely in humans.
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Fall of Misinformation Series: Ionica Smeets
Misinformation spreads easily and fast. It gets presented as news, whereas actual news gets dismissed as fake. Conflicting streams of information allows all sides to cherry-pick whatever is most comfortable, boosting degrees of confidence and confusing the deliberation of both politicians and voters.…
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Fall of Misinformation Series: Suzan Verberne
Misinformation spreads easily and fast. It gets presented as news, whereas actual news gets dismissed as fake. Conflicting streams of information allows all sides to cherry-pick whatever is most comfortable, boosting degrees of confidence and confusing the deliberation of both politicians and voters.…
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The immune system: step it up or slow it down?
When foreign matter enters our body, our immune system has to make a choice whether or not to go on the attack. There are times when the system goes wrong, and we end up with an illness or an allergic reaction. Researchers at LUMC are trying to steer the immune system. The dossier on Immunity, Infection…
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A chemical connection that affects your immune system
A group of chemists, that includes Sander van Kasteren and Hermen Overkleeft, has discovered that azides, a certain type of chemical compound, can determine whether or not T cells respond to or ignore a vaccine. Their discovery is set to be published in Angewandte Chemie.
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How Leiden's drug pioneers have switched to Covid research
From studying molecules in the blood of corona patients to developing a new concept for vaccines. The Leiden Academic Centre for Drug Research (LACDR) has transformed many ongoing projects into Covid research projects. Hubertus Irth, scientific director of LACDR, talks about the role of his institute…
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Werken aan een effectiever malariavaccin
In het Leids Universitair Medisch Centrum wordt gewerkt aan de ontwikkeling van een nieuw malariavaccin dat effectiever is dan de huidige vaccins.
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The quest for new medicines against tuberculosis
Can drug screening for tuberculosis treatment be made more efficient?
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Research in Africa reduces health spending and prevents diseases of affluence
Health workers have always sought ways to fight disease in vulnerable groups in the population. It is now clear that such research also benefits more prosperous countries. African worm infections and innovative thermometers have shown Leiden researchers how to fight diseases of affluence and keep health…
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Research
Research at the SBC group is comprised of the following research themes:
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New statistical method brings together studies at an early stage
During the coronavirus pandemic, scientists were in a hurry to find drugs that would help fight the disease. To combine the research that was being carried out around the world, PhD candidate Judith ter Schure developed a new statistical method: ALL-IN meta-analysis. This helps determine sooner whether…
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Our man in Jakarta keeps the institute running from Venlo
The COVID-19 pandemic forced many staff of Leiden institutes abroad to leave their posts in a hurry. How is the KITLV Jakarta team doing now? Director Marrik Bellen talks about the turbulent times for this Leiden institute and its staff. And can we learn anything from the Indonesian approach?
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From in-person lectures to a first-class degree: our year on social media
Covid year 2021 might have felt somewhat less strange than the year before, but the virus still left its mark on University life and our students and staff. Fortunately there was also room for research, visiting dignitaries and in-person classes. And our social media accounts weren’t only about covid…
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Making the invisible visible with ‘click chemistry’
Sander van Kasteren (Professor of Molecular Immunology) makes the invisible visible. He will explain more in his inaugural lecture.
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How do we maintain a healthy biological clock?
During Seeing Stars Leiden all the lights around Leiden Observatory will be switched off for an hour. The more lights that go out, the more stars we’ll be able to see. For the LUMC, this is the perfect moment to think about our biological clock, the topic researchers from the BioClock consortium are…
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ERC Consolidator Grants for four Leiden researchers
The European Research Council has awarded ERC Consolidator Grants to four researchers from Leiden. These grants of up to 2m euros will enable them to continue and expand their research.
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Six Leiden researchers receive ERC Starting Grant
Six researchers from Leiden University have received an ERC starting grant. This grant of on average 1.5m euros will enable the researchers to launch their own project, form their own research team and develop their best ideas.
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Vidi grant for seven researchers from Leiden University
From malaria parasites as a vaccine to how top-level bureaucrats reach their decisions: seven researchers from Leiden University have received a Vidi grant from the Dutch Research Council (NWO). This 800,000-euro grant will enable them to develop their own innovative line of research over the next five…
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Leiden researchers join forces against tuberculosis
About one and a half million people worldwide die each year from tuberculosis. For thirty years, therapy with antibiotics has been the same, while it takes far too long and can lead to resistant pathogens. Leiden researchers from four institutes are now joining forces to develop more effective and efficient…
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AAPS Fellowship Award for Professor Wim Jiskoot
Wim Jiskoot has been honored by the American Association of Pharmaceutical Scientists as an AAPS Fellow.
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Blog Post | Diplomacy’s Response to the Coronavirus (Part II)
The previous blog post in this series discussed the role of international diplomacy during the coronavirus crisis. This post focuses on diplomacy and its challenges in post-corona times. Specifically, the blog post argues that diplomats will face a range of challenges following the Covid-19 pandemic…
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Assistant professor "Inflammation pathways in atherosclerosis"
Science, Leiden Academic Centre for Drug Research (LACDR)
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Steering the immune system with liposomes
Liposomes – nano-sized spheres composed of fatty molecules – are very promising for vaccination. Bio-pharmaceutical scientist Naomi Benne discovered that the immune response in animal models can be steered by varying the charge of the liposomes. She obtained her PhD degree on 8 September for this research,…
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Anne Meuwese and Bart Custers in Trouw on Covid apps
The more people are vaccinated, the more society can slowly reopen. Technological developments, like the Covid passport and other apps, can play a role in this. Artificial Intelligence could help greatly in developing the vaccine passport and the Covid-19 exposure notification app, Anne Meuwese and…
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GP in the Bible Belt: does God play a role in consultations?
Jaïr van Rhenen studied Medicine in Leiden and is now a GP in the largely religious Veenendaal. Before this, he worked as a tropical medicine doctor in Lesotho. ‘If you have the prospect of an afterlife, you often respond differently to illness.’
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Test certificate could help reopen society, but at what cost?
On 11 May the House of Representatives voted in favour of a law that will enable some sectors to reopen sooner than planned with the aid of test certificates. Political philosopher Josette Daemen is critical of the new legislation. ‘Just because we get used to measures doesn’t make them desirable.’
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In Memoriam professor Wim Jiskoot (1961-2021)
Afgelopen zondagavond, 22 augustus, is na een kort ziekbed onze zeer gewaardeerde collega professor Wim Jiskoot, Hoogleraar Technologie van toediening van medicijnen, overleden. Wim werd twee weken geleden onverwachts geconfronteerd met het feit dat hij een vergevorderd stadium van kanker had, waarvoor…
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Third prize awarded to Pim Schipper for oral presentation at GPEN conference
Pim Schipper has won the third prize for his oral presentation during the tenth biennial meeting of the Globalization of Pharmaceutics Education Network (GPEN), which was held from 27 – 30 Aug 2014 at the University of Helsinki, Finland.
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Cairo Institute Director: ‘I’m keeping the ship afloat’
In March 2020, the Netherlands-Flemish Institute in Cairo suddenly had to repatriate 57 students to the Netherlands and Flanders. Director and Arabic specialist Rudolf de Jong decided to stay in Egypt. ‘A lot of the work carries on.’
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Hester Bijl: ‘On-campus teaching is a big step forward, so take care’
‘We’re going to see each other again on campus. We’re so pleased, but we do have to say safe.’ Rector Magnificus Hester Bijl is looking ahead to the new academic year, which begins on 6 September. No more 1.5m distancing, but we do have to take responsibility for other people’s safety.
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Bio Science Park generates thousands of jobs and millions of euros for the Leiden region
The Leiden Bio Science Park (LBSP) is very important not only for the city of Leiden but also for the Leiden region and the Netherlands as a whole. This is the finding of an investigation conducted by the Leiden-Leiderdorp Audit Committee. The large-scale development of the LBSP in recent years has…
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Major Expansion Leiden Quantum Computing
The 18.8 million euro NWO Zwaartekracht grant for quantum software which Amsterdam, Delft and Leiden landed collectively, means for Leiden University among others the appointment of two new permanent scientific staff members, who will each form their own research group, divided among Computer Science,…
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Statistics & Data Science (MSc)
The master’s programme Statistics & Data Science provides students with a thorough introduction to the general philosophy and methodology of statistical modelling and data analysis. The programme has two specialisations: Data Science and Statistical Science.
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Vision and Mission
The need for novel drugs as well as innovations in their development and application is as urgent as ever. Below we present our vision , mission, and our key research areas.