1,738 search results for “ancient dna” in the Public website
- Laboratory for Ceramics Studies
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Fighting tumours with light
Chemotherapy that does nothing until you irradiate it with light. Sylvestre Bonnet receives a Vici grant of 1.5 million euros for the development of this treatment. The Leiden chemist wants to build a new molecule to fight tumours that are at the time still difficult to treat.
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The researchers
Professor of Ecotoxicology Martina Vijver and lecturer Maarten Schrama are the founders and managers of the Living Lab. As well as these two researchers, a number of other ecologists and biologists are involved in the research at the Lab.
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Quantifying nucleosome dynamicsand protein binding with PIE-FCCS and spFRET
In this thesis I describe the results of Pulsed Interleaved Excitation and Fluorescence (Cross) Correlation Spectroscopy (PIE-F(C)CS) combined with single-pair Förster Resonance Energy Transfer (spFRET) used to study dynamics in single nucleosomes, which depends on subtle differences in the length of…
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Our approach
Our group operates at the cross-roads of different disciplines: molecular and cellular microbiology, biochemistry, structural biology and biophysics. The group harbors expertise in a multitude of molecular and cellular approaches including:
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Responding to environmental cues: the adaptive qualities of chromatin compaction proteins
Promotor: M. Ubbink, Co-Promotor: R. T. Dame
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Helmut Schiessel Group - Theoretical Physics of Life Processes
The group Theoretical Physics of Life Processes, led by Helmut Schiessel, focuses on the physics of chromatin, the DNA-protein complex that fills the nuclei of eukaryotic cells.
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Self-assembly of Colloidal Particles
The miniaturization of machines towards the micron and nanoscale requires the development of joint-like elements that enable and constrain motion. We developed a facile method to create colloidal joints, that is, anisotropic colloidal particles functionalized with surface mobile DNA linkers that control…
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Centre for Microbial Cell Biology
The CMCB brings together microbial cell biology expertise in Leiden. It aims at optimal resonance between the groups and maximal exploitation of the available infrastructure and to develop innovative cross-boundary technology platforms.
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SDS-PAGE at the nanoscale: A nanorecorder for single molecule protein sequencing with graphene
Can we find new chemical and biological sensing routes on the edge and surface of graphene to improve the potential of graphene to act as a sensor?
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Moving Romans. Migration to Rome in the Principate.
Moving Romans offers an analysis of Roman migration by applying general insights, models and theories from the field of migration history.
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Paul Hooykaas
Science
p.j.j.hooykaas@biology.leidenuniv.nl | +31 71 527 4933
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synthesis of metal-based chemotherapeutic agents for targeted DNA interactions or DNA repair pathway modulation
PhD defence
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On Composition in Herodian’s History of the Roman Emperors
In the History of the Roman Emperors, what does Herodian’s method of composition consist of and how does it relate to his writing intention, particularly in terms of political and moral idea(l)s?
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Learning from the past
Leiden archaeologists investigate how people in the past impacted their environment. Together with scientists, environmental scientists, and humanities experts, they use this information to draw conclusions about the present – and show what we can learn from it for the future.
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The Figure of Abraham in the Metrical Homilies of Jacob of Sarug: Its Literary and Theological Context
This project is a close and sensitive contextual study of Jacob of Sarug's (ca. 451-521 AD) metrical homily
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Asia Beyond Boundaries
Beyond Boundaries: Religion, Region, Language and the State is a major multidisciplinary research project which aims to re-vision the history of Asia in one of its most significant periods. The project is based at the British Museum, British Library and the School of Oriental and African Studies, and…
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Introducing: Damjan Donev
Damjan Donev is a PhD student in the ERC granted research project 'An Empire of 2000 Cities: urban networks and economic integration in the Roman empire', directed by Luuk De Ligt and John Bintliff (Archaeology).
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Meeting with the ambassador of Kenya about research collaboration
A delegation of the Institute of Environmental Sciences (CML) of the Faculty of Science of Leiden University, led by the Dean of the Faculty of Science: Prof.dr. Geert de Snoo, visited the Kenyan ambassador Mr. Lawrence Lenayapa and his staff on Monday 29 of October in The Hague.
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About the programme
The one-year (60 EC) master in Classics and Ancient Civilizations provides intensive and comprehensive training covering the entire range of present-day research on the ancient civilizations of Greece and Rome and the Ancient Near East.
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PhD Theses
A full overview of MacBio PhD Theses.
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Charlotte van der Voort
Faculty of Humanities
c.van.der.voort@hum.leidenuniv.nl | +31 71 527 2125
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Fokelien Kootstra
Faculty of Humanities
f.kootstra@hum.leidenuniv.nl | +31 71 527 2727
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Marike van Aerde
Faculteit Archeologie
m.e.j.j.van.aerde@arch.leidenuniv.nl | +31 71 527 1138
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Fungal Chitosans from Fermentation Mycelia for Plant Biostimulants (FunChi)
Our focus is to optimize the fungal cell wall to both increase chitin production and chitin extractability.
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Horizontal gene transfer and spreading of biosynthetic gene clusters and antimicrobial resistance
Biosynthetic gene clusters (BGCs) for natural products are widespread in microbial genomes, and they are rapidly exchanged. This research assesses the factors that control the spread of BGCs and resistance genes in nature. This includes risk assessment for the spread of engineered DNA in nature.
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Overcoming the Debye screening length with radiofrequency-operated graphene biosensors
Can a proposed new radiofrequency approach to graphene biosensors lead to groundbreaking changes in genome mapping?
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Involvement of host and bacterial factors in Agrobacterium-mediated transformation
Agrobacterium tumefaciens, a gram-negative plant pathogen belonging to the family Rhizobiaceae, is the causative agent of crown gall disease, which can affect many plant species including agronomically important ones.
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Bacterial Chromatin
The relative simplicity of the bacterial cell, short generation times and well defined and inexpensive culturing conditions have significantly contributed to our understanding of many complex biological systems. Yet the workings of the bacterial genome, seemingly impossibly compressed within a tiny…
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The mechanism of Agrobacterium-mediated transformation of eukaryotic cells
We aim to unravel the molecular mechanisms involved in the transformation of eukaryotic cells by Agrobacterium.
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Discovery of antibiotics and their targets in multidrug-resistant bacteria
Global healthcare is on the verge of an antibiotic availability crisis as bacteria have evolved resistance to nearly all known antibacterials. Identifying new antibiotics that operate via novel modes-of-action is therefore of high priority.
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Macromolecular Biochemistry
Macromolecular Biochemistry is a section of the Leiden Institute of Chemistry at Leiden University, comprising the PIs Marcellus Ubbink, Remus Dame, Aimee Boyle, Lars Jeuken and Anne Wentink.
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Quantitative live cell imaging of glucocorticoid receptor dynamics in the nucleus
In this thesis, the focus lies on studying glucocorticoid receptor dynamics in living cells with the aim of understanding how this transcription factor finds its DNA target sites to regulate transcription.
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About
Leiden Center for the Study of Ancient Arabia
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ERC Advanced Grant for Frans Theuws
Prof. dr. Frans Theuws has received an Advanced Grant from the European Research Council (ERC). The 2,5 million euro grant will be used in a 5-year Archaeological study into the economic recovery of Western Europe after the demise of the Roman empire.
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Archaeologist Wei Chu explores Carpathian caves with Gerda Henkel grant
Recently, archaeologist Dr Wei Chu received a grant from the Gerda Henkel Stiftung for an excavation in the Carpathian Mountains. Originally planning for an excavation in Ukraine, his plans were disrupted by the war. ‘We had to change plans really quickly.’
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EUR 15 million for excellent archaeological research into the colonisation of the Americas
Corinne Hofman (Professor in Caribbean Archaeology) has been awarded 15 million euro by the EU for her archaeological research on the colonisation of the Americas. She will lead the ‘NEXUS 1492’ project together with colleagues Davies (VU), Brandes (Konstanz) and Willems (Leiden).
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Archaeological Sciences
With the emergence of new methods and technologies such as improved DNA analysis and big data, archaeological research has changed radically in recent decades. The researchers from the Department of Archaeological Sciences at the Faculty of Archaeology use new scientific knowledge to answer fundamental…
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Extra-curricular
The Classics and Ancient Civilizations programme offers many extracurricular opportunities to enrich your study experience.
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Extra-curricular
The Classics and Ancient Civilizations (Research) programme offers many extracurricular opportunities to enrich your study experience.
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Extra-curricular
The Classics and Ancient Civilizations programme offers many extracurricular opportunities to enrich your study experience.
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Extra-curricular
The Classics and Ancient Civilizations programme in Egyptology offers many extracurricular opportunities to enrich your study experience.
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Greek criticism and Latin literature. Classicism and cultural interaction in the late republican and early imperial Rome
This project examines the intriguing relationship between Greek literary criticism and Latin literature in Rome (first centuries BC and AD).
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The Ra's al-jinz project (Oman)
The Ra’s al-jinz project tackles economic diversification and social complexity in non-urban societies, from the perspective of Eastern Arabia, by exploring the Early Bronze Age settlement of Ra’s al-jinz RJ-3.
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The Mesoamerican codex re-entangled: Production, use, and re-use of precolonial documents
This dissertation is concerned with the study of the less than twenty remaining precolonial Mesoamerican codices. By considering these rare and fragile pictographic and hieroglyphic books from the cultural biography perspective, many different aspects of these books can be studied.
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Hellenistic economic thought
This subproject of 'From Homo Economicus to Political Animal' analyzes Greek economic thinking of the Hellenistic period.
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Ancient History (UMW) Research Seminar
Lecture, Ancient History (UMW) Research Seminar and Ancient Worlds Network Lecture
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About the programme
The MA Classics and Ancient Civilizations covers one year and can be studied in four tracks: Classics is one of them. While diving into the literary, cultural and intellectual worlds of Greece and Rome, you will be involved in current research, and stimulated to reflect on the significance of Classics…
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Extra-curricular
The Classics and Ancient Civilizations programme in Assyriology offers many extracurricular opportunities to enrich your study experience.
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Extra-curricular
The Classics and Ancient Civilizations (Research) programme in Egyptology offers many extracurricular opportunities to enrich your study experience.