429 search results for “regenerative tissue” in the Public website
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The African lion consists of two subspecies
Biologist Laura Bertola argues that the traditional separation of lions into African and Asian subspecies is incorrect. She has discovered that Africa is actually home to two subspecies. Her PhD defense was on 18 March 2015.
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ERC Consolidator Grants for four Leiden researchers
From fake news via WhatsApp to mini hearts from a 3D printer: four Leiden researchers have been awarded a Consolidator Grant by the European Research Council. These grants, of up to 2m euros, enable researchers to establish or expand their research team and continue to develop their career.
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Vici grants for 7 Leiden researchers
Seven Leiden researchers have been awarded a prestigious Vici grant by the Netherlands Organisation for Scientific Research (NWO).
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Immune system plays dual role in breast cancer
The immune system plays a paradoxical role in the spread of breast cancer. Some immune cells contribute to metastasis, while other cells can be activated to strengthen the effect of chemotherapy. Kelly Kersten made this discovery in her PhD research. PhD defence 7 February.
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Partnering with businesses to scale up metabolism research
Predicting whether someone will fall ill and which treatment will benefit them most: that is the aim of the techniques that Professor of Analytical Biosciences Thomas Hankemeier and his research group are developing at Leiden University. In order to scale up and further develop this technology, he works…
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Is it possible to avoid dehydration? Gene promotes wood formation
‘It was a discovery we did not expect,’ says Remko Offringa, professor of Plant developmental genetics. Today he publishes a new trait of a versatile gene in Current Biology: it makes the difference in plants between herbaceous and woody stem growth. A useful feature to prevent dehydration.
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ERC Synergy Grant to unlock sugar codes for health and a sustainable society
Hermen Overkleeft and his colleagues Gideon Davies (University of York) and Carme Rovira (University of Barcelona) will receive a 9.1 million euros Synergy Grant from the European Research Council. Together, they will form the Carbocentre Synergy team for research into enzymes that work on glycans:…
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Ecologist Michiel Veldhuis is the Discoverer of the Year 2020
Michiel Veldhuis received the most public votes for the C.J. Kok Public Award and may therefore call himself Discoverer of the Year. Veldhuis researches how climate change affects savannah ecosystems in Africa and how we can protect them.
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Why do birds flock? Shedding light on collective motions in heterogeneous populations
Leiden physicists Alexandre Morin and Samadarshi Maity study self-organisation and flocking phenomena. They shed light on flocking, which helps to understand how it is possible that birds in a flock don't collide. With plastic microbeads, they create an experimental setup and they developed a mathematical…
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Smallest-ever Leiden University logo
The logo of Leiden University, with letters as small as a bacterium. Researchers from LUMC and the Institute of Biology have created the smallest logo of our university ever produced. It is a piece of fun with a serious real-world application: the new microscope with which the logo was made allows scientists…
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Mathematical model predicts drug concentration in the brain
Do medicines arrive in the right amount at the right spot in our brain? By making a model that depicts our brain in small 'brain blocks', Esmée Vendel tries to find an answer to this question. Her new, mathematical model predicts the concentration of medicines in the brain over time and space. Vendel…
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Ebola-on-a-chip: Leiden scientists against a fatal virus
Although Ebola is a virus with significant fatality rates, we still lack effective countermeasures to battle it. To change this, Alireza Mashaghi and his colleagues from the Leiden Academic Centre for Drug Research have successfully developed an organ-on-a-chip model that imitates the most dangerous…
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Michael Ignatieff appointed Cleveringa Professor at Leiden University
Michael Ignatieff, Canadian author, university professor and former politician, has been appointed Cleveringa Professor for the 2013-2014 academic year at Leiden University, the Netherlands. Professor Ignatieff will deliver the Cleveringa lecture on 26 November 2013.
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How cells determine the fate of proteins (and can we do it too?)
Cells in our bodies are often threatened by errors in our own proteins. The FLOW consortium, comprising scientists from various institutions including Leiden, is poised to meticulously map out for the first time how cells control proteins, correcting or removing faulty ones. This endeavour holds promise…
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Preventing heart attacks by earlier detection of cardiovascular disease
In the Netherlands, 1.55 million people suffer from cardiovascular diseases. Yet, acute cardiovascular events, such as a heart attack or stroke, often occur unexpectedly. That is because many people do not know they are at risk for such an event. Immunological researcher Amanda Foks and her colleagues…
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How cells talk by pulling on a fibre network
Mechanics play a larger role in blood vessel formation, and other developmental biology, than previously thought. Cells appear to respond to mechanical signals, such as pressure. Through the extracellular matrix, a network of fibrous proteins, cells can supposedly exchange those mechanical signals over…
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Chasing nanoplastics
How dangerous are micro- and nanoplastics? Do they affect the environment? What harm can they do to our bodies? Questions that we can now finally answer because of Fazel Abdolahpur Monikh. Together with his colleagues, he developed a method to detect and quantify nano-sized plastics. Their paper has…
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Towards no more glass in the jam with better X-ray scanners
X-ray and CT scanners are widely used devices in research, diagnostics and the industrial sector. And yet they are not nearly as fast and accurate as we would like. Mathé Zeegers is researching the newest technique in the field at the Centre for Mathematics and Computer Science: spectral X-ray imaging.…
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New zebrafish study to understand human cancer
Ewa Snaar-Jagalska, Shuning He and colleagues from IBL, LION and LACDR reported on a new zebrafish study to understand micrometastasis of human cancer cells. They discovered a novel role for neutrophils in assisting metastasis formation, which provides critical insights for anti-cancer therapies.
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Grants to build large-scale research facilities
Five projects with researchers from Leiden University have received a grant from the Dutch Research Council (NWO) to build or upgrade existing research facilities.
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Bacteria inside plant roots battle fungal disease
Two bacterial species team up inside the plant root system to rescue their host from fungal infection. This was discovered by a team of microbiologists and bioinformaticians from the Netherlands Institute of Ecology, Wageningen University, and the Institute of Biology Leiden. They also identified the…
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New insight into immune cell behaviour offers opportunities for cancer treatment
An international group of scientists has discovered that certain cells of our immune system – the so-called T cells – communicate with each other and work together as a team. To fight an infection they stimulate each other’s growth, but at the same time, they inhibit each other when there is a surplus…
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‘Skin injection could allow us to vaccinate up to five times more people from the same supplies’
The current COVID-19 vaccination campaign involves injecting the vaccine into muscle tissue, but injecting a smaller amount of vaccine in the skin might also provide good protection. The #wakeuptocorona crowdfunding campaign has enabled Anna Roukens (LUMC) to examine the safety and efficacy of vaccination…
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New measuring method facilitates drug research
Leiden chemical biologists led by Dr Mario van der Stelt have developed a method to facilitate the search for new drugs. This method has allowed them to take an important first step in the development of a drug against obesity.
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Aggressiveness of cancer cells halted
Zebrafish-human communication shows that cancer cells lacking a signaling protein are less able to develop aggressive metastatic properties. This discovery has been made by molecular cell biologist Claudia Tulotta. PhD defence 14 June.
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Four Leiden consortia awarded large NWO grants
No less than four Leiden research teams have been awarded a grant by NWO. On 27 July NWO honoured 21 applications in the Open Competition ENW-XL. NWO awards the grants to consortia in the exact and natural sciences who are doing unconnected fundamental research that is 'driven by curiosity'.
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Two-pronged attack on infectious diseases
A combination of two potential drugs gives hope of a 'super blockage' of an over-active immune system, Leiden researchers report in Nature. The breakthrough came from the crystallisation of a membrane protein.
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Nanoparticles: shapeshifters that pass along the food chain and end up in the brain
Nanomaterials can pass much further along the food chain than was previously thought. The particles can change shape and size in each organism, enabling them to pass on to the next one in the chain. Researchers from the Institute of Environmental Sciences discovered this accidentally when using a novel…
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Researchers reveal how stem cells make decisions
Embryonic stem cells have the remarkable ability to develop into any type of cell. On their way to become for example a liver or a heart cell, they must repeatedly decide between alternative developmental paths. How they make these decisions is largely unknown. An international team of biophysicists…
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Innovating Cell Pharmacy with stem cells
Lecture
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Consortia awarded grant for research into pressing issues
Various consortia in which Leiden University is represented are beginning interdisciplinary research, which will bring scientific and societal breakthroughs within reach. Knowledge institutions, government and private parties are working closely together on the projects.
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How to develop cancer drugs with less side effects
Lecture, Tuesday Talks: Science Insights
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Separating waste, and then...?
What happens to the different waste streams?
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ICM 2018 project results
Within the ICM 2018 project, Leiden University cooperated with 25 partner universities from 14 countries. In total, 97 mobilities were granted to this project - 65 mobilities were realised (some mobilities had to be ended prematurely due to covid-19, others were finished online).
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YAL members
Read all about YAL membership and the members of the Young Academy Leiden.
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Organ failure caused by viruses, how does it work? Now there are methods to find out
Dying from viral infection due to organ failure and blood loss: we still know little about how it can happen. Among other things, Huaqi Tang developed an organ-on-a-chip to figure it out. 'These technologies can offer unprecedented opportunities to fight the viruses that threaten our society.' Tang…
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Medical Delta professor Marcel Reinders: ‘You need collaboration to make a real impact’
Prof. Marcel Reinders is a data science specialist at Delft University of technology. Using smart algorithms, he searches for links in complex data. For example, he studies patterns in DNA that lead to aberrant cell behaviour. This knowledge will help detect serious diseases such as Alzheimer's and…
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Medical Delta professor Marco van Vulpen: ‘I advocate the introduction of the share factor’
Proton therapy is a new way of treating cancer in which radiation doses are delivered more precisely. This results in less damage to surrounding tissue and fewer side effects. Professor Marco van Vulpen is medical director of HollandPTC in Delft, where the social value of this therapy is studied. Van…
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SBB trip to Boston, USA
Let’s admit it, in an era of fast paced global dynamics and growing society needs, biotech becomes crowned as the king among the “coolest” industries. Boston is considered to be at the heart of these biotech events. What it really is though, is the heart of innovation itself. There is a very strong…
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‘Make science communication more work and less hobby’
Young researchers met this month for the fifth Science Communication Summer School. ‘This is the first time some participants get to meet other researchers who also enjoy science communication. It’s great to see’, says Julia Cramer, one of the coordinators.
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50 jaar MRI: Hoe het LUMC dit betaalbaar maakt
50 years ago Lauterbur published the basic principle of MRI. Sine then MRI has become more expensive. Professor Andrew Webb describes what is needed to make MRI available for everybody.
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Veni grant for ten Leiden researchers
Ten Leiden researchers have been awarded a Veni grant by the Dutch Research Council (NWO). The grant, of up to 280,000 euros, will enable them to elaborate their ideas over a period of three years.
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Leiden University shows its face on 3 October
Leiden University celebrated the Relief of Leiden with the 3 October University. This year the University also took part in the festive parade, to promote 444.
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Improving nature’s antibiotic
'What nature made isn’t necessarily an optimized medicine to use in the human body,’ says Professor of Biological Chemistry Nathaniel Martin. That’s why a group of Leiden researchers is making a chemistry-based improved version of the frequently used antibiotic vancomycin. They received an NWO NACTAR…
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In conversation with the head of the rodent facility
Before patients can take a pill, scientists often spend years in the lab developing and testing a candidate drug. That often includes experiments with laboratory animals. As head of the rodent facility, Ilze Bot and her colleagues ensure that these experiments are conducted in an ethically responsible…
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Scientists find strong evidence that wasting syndrome is the same for all organisms
An interdisciplinary team of Leiden researchers has discovered that wasting syndrome, a severe byproduct of tuberculosis, is the same for all humans and animals studied. The discovery offers new opportunities to investigate the still insufficiently understood condition. The scientists also developed…
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Studying with a disability: 'Accessibility alone is not enough'
How can we make studying easier for students with a functional disability? This will be the key question during a public conference on 20 April. Romke Biagioni (Fenestra) explains why there is such a need for this conference. Are you going to be there?
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Gravitation grants for three major research programmes
Three major research projects involving Leiden scientists have been awarded a grant from NWO’s Gravitation Programme. The projects are on innovation processes, organs-on-chips and quantum software.
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How genetic research contributes to effective lion conservation
Human measures to protect lions have an impact on the genetic health of populations. Leiden and Kenyan scientists discovered this by analysing the DNA of 171 Kenyan lions. ‘By fencing reserves, for example, the chance of inbreeding increases.’ With the knowledge and tools from the research, management…