326 search results for “trisomie x” in the Public website
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A computational study of structural and excitonic properties of chlorosomes
The long-held desire - to link structure directly to function and to explain molecular mechanisms based on basic chemical or physical principles - is finally coming closer, satisfying not only our scientific curiosity but also offering new solutions to the many challenges in the field of health, energy…
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LUCIS - Centre for the Study of Islam and Society
LUCIS promotes high-quality research on Islam and Muslim societies and actively communicates the insights and findings of that research to the larger public.
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Adsorption and catalysis on Pt and Pd monolayer-modified Pt single crystal electrodes
The focus throughout this thesis will be on gathering fundamental studies of the detailed structure and composition of the electrode/electrolyte interface effect on the rate and mechanism of key electrocatalytic reactions.
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Electives
ACPA offers electives in visual arts, music or music philosophy. As a student of Leiden University or the University of the Arts The Hague* you can choose these electives offered by ACPA.
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Luca Giomi Group - Soft and Bio Mechanics
We are interested in understanding the mechanics of soft materials, of which biological materials are prominent examples.
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Veluwe
In 2019 citizen scientists inspected elevation maps of the Veluwe region and discovered several thousand potential new archaeological structures. The project started as exploration into the potential of citizen science in Dutch archaeology, but developed into a fully flexed project in which citizen…
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Van Marum Colloquium: Proton-coupled electron transfer at interfaces: the importance of non-ideal isotherms
Lecture
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Light-activatable metallodrugs and metal-functionalized liposomes
Metal-containing molecules combine geometrical features and a reactivity that are inherently different from that of organic molecules. My research focuses on light-activatable metal-based anticancer drugs and metal-functionalized liposomes. Light is a very selective way to activate photosensitive drugs…
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Emergency recording of Chontales style sculpture at the El Gavilán site, Central Nicaragua
The scientific interest in stone sculpture has been present in the archaeological investigation of Nicaragua from the mid 19th century onward.
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Art
When you walk into the Gorlaeus Building, you will notice it immediately; the artwork 'The Cloud' hangs prominently in the hall and cannot be missed. Artist Jos Agasi designed it especially for this location. ‘Intuition, imagination and creativity. Scientists and artists have more in common than they…
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Lipid signaling in brain diseases
Multiple Sclerosis, Parkinson’s and Alzheimer’s disease are the most common neurodegenerative disorders. Unfortunately, no effective treatments are currently available to halt the progression of these neuroinflammatory diseases [1].
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Casting Call: How does a European politician save a refugee from drowning? - installation by Eleni Kamma
Would it be possible for local and traditional European forms of parrhesiastic theater—by which Eleni Kamma means events, actions, and performances staged by characters who courageously speak their minds through scenes of excess and laughter, that take place in public view and incite the spectator’s…
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About the programme
The specialisations Art History and Museum Studies both engage in critical perspectives and in current practices and the development of a professional network. The specialisation Museum Studies focuses on the art museum and places it in an artistic, cultural, social and political context. Our courses,…
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About the programme
The specialisations Art History and Museum Studies both engage in critical perspectives and in current practices and the development of a professional network. The specialisation Art History puts emphasis on the analysis of art works within a museal and curatorial context. Our courses, taught by art…
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Resources & Readings
Below are resources which provide a short primer on the subject of active learning.
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The Anatomy Lesson of Dr Nicolaes Tulp
Nicolaes Tulp (1593-1674) studied medicine in Leiden. He attended lectures in the Academy Building and was taught anatomy in the former Faliede Begijn church, now the ‘Old Library’ (Oude UB) building, for a long time the location of the anatomical theatre. Shortly after his move from Leiden to Amsterdam,…
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Teacher Learning Through Novice-expert Interaction in the Context of Chinese Vocational Education
The aim of this research is to gain insight into the approaches of learning to teach. Teacher learning processes, feedback in novice-expert interaction and the impact of the interaction are explored.
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The development of public speaking anxiety in youth
Does the public speaking anxiety that many youngsters experience originates from specific characteristics in their earlier development?
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Metabolomics and Analytics Centre
The ambition of the Metabolomics and Analytics Centre led by Thomas Hankemeier is to develop innovative analytical strategies for metabolomics-driven health monitoring and systems biology studies. Understanding the intricate balance between health, disease and adaptation to challenges relies on the…
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Book presentations
Now and then we organise book launches to present the latest publications, both academic and popular, in our broad field.
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Education
Cooperation on education with China stimulates innovation and brings a different perspective and new content to classrooms.
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To explore the drug space smarter: Artificial intelligence in drug design for G protein-coupled receptors
Over several decades, a variety of computational methods for drug discovery have been proposed and applied in practice. With the accumulation of data and the development of machine learning methods, computational drug design methods have gradually shifted to a new paradigm, i.e. deep learning methods…
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Portrait of Marten Soolmans
Marten Soolmans (1613-1641) studied law in Leiden at the same time that Rembrandt lived in the city. Rembrandt painted Soolmans and his wife Oopjen in 1634, after all three had moved to Amsterdam. This remarkable portrait of the sumptuously dressed Soolmans can be seen at the Kamerlingh Onnes Building,…
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Saskia as Flora
Rembrandt painted this Flora, the Roman goddess of spring, in 1635. She is on display above the archway leading from the Academy Building to the lush flora of the University’s Hortus Botanicus. Rembrandt, who had his own cabinet of curiosities, almost certainly knew this botanical garden, the oldest…
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Self-Portrait with Gorget
In this penetrating self-portrait dating from around 1629, Rembrandt presents himself as an aristocratic young man. He enrolled in Leiden University as a student of the arts in 1620, but whether he actually attended lectures is unknown. In his paintings and prints, he incorporated many topics that are…
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Minerva in her Study
Following its foundation in 1575, Leiden University was quick to incorporate Roman goddess Minerva in its coat of arms. This explains why Rembrandt’s Minerva from 1635 can be seen on the façade of the Academy Building, which has been in use by the University since 1581. This is where, in the Senate…
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Proteochemometrics
Research question
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Triceratops Bonebed Excavation
Since 2013, the National Natural History Museum of the Netherlands, Naturalis Biodiversity Center, is unearthing the largest bonebed of the horned dinosaur Triceratops discovered so far. In order to answer questions about sedimentology, taphonomy and palaeobiology, palaeontologists and geologists collaborated…
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Aarts Lab - Magnetic and Superconducting Materials
In the Aarts lab we combine or structure materials, mostly in thin film form, in such a way that the hybrid has different and novel properties or functionalities.
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Self-Portrait in a Heavy Fur Cap
Leiden University Library holds two drawings and in the region of a hundred prints by Rembrandt, as well as works by his pupils and the staff of his studio. That explains why this self-portrait etching dating from 1631, his Leiden period, can be seen on the façade of the University Library.
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Key publications
Key publications of the Medical Systems Biophysics and Bioengineeringgroup (Mashaghi Lab)
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Representation, Presence, and Theatricality in 16th-century Italian theatres
Subproject of
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Teacher motivation and teaching
University-school partnerships are important constellations for teachers’ professional learning. The present study investigates how both teacher characteristics and contextual factors are related to teachers’ motivation to participate in the university-school partnership, and the relationship between…
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Kamerlingh Onnes Building
Steenschuur 25, Leiden
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Activity-based protein profiling for drug discovery
Activity-based protein profiling (ABPP, also termed chemical proteomics), is one of the pillars of chemical biology, and at LED3 we have taken it to the next level. ABPP allows the assessment of protein function in live cells and tissues, which means that the activity of a complete protein family can…
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Small Grants 2023 Research Projects
The LUCDH foster the development of new digital research by awarding a number of Small Grants each year. As in previous years the LUCDH received a large number of excellent grant applications for Research and Personal Development funds. Congratulations to the recipients of this year's research award…
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Publications
Recent publications
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Coptic Studies
There are currently two projects in Coptic Studies that are supported by the NVIC. Both are directed by Dr. Karel Innemee and both take place in the Wadi Natrun.
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Social Citizenship & Migration
Social Citizenship & Migration (SCM) is one of the nine interdisciplinary programmes launched by Leiden University in 2020. It is led by the Faculties of Governance and Global Affairs, Law, Humanities, and Social Science.
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Elise Dusseldorp: ‘Algorithms can see whom a treatment will work for’
Imagine how much time, money and discomfort it would save: a personalised treatment for each individual patient. Precision medicine like this is coming ever closer, thanks in part to Elise Dusseldorp’s algorithms. They retrieve a wealth of information from research data.
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The Centre for Digital\\Jurisprudence
Online platforms such as YouTube, Facebook, and X (formerly Twitter) have become part and parcel of everyday media use. Journalists incorporate posts from politicians into newspaper reports, scientists share their insights in short posts or videos, and the judiciary uses social media to explain their…
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Development of Quantitative Nanostructure Activity Relationship (QNAR) Models Predicting the Toxicity of Metal-based Nanoparticles to Aquatic
Describe and identify what dosimetry parameters are of importance to interpret dose-response relationships (eg., mortality, sub-lethal, growth or reproduction inhabitation, DNA damage and reactive oxygen species, etc. ) for metal-based nanoparticles? How to develop quantitative models that enable to…
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Diego Garlaschelli Group - Econophysics and Network Theory
We study the structure, dynamics and physics of complex networks emerging from the intricate interconnectedness of the constituents of large systems.
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History Painting
Rembrandt experts have been puzzling over this painting from 1626 for years. The work may have been commissioned by someone from University circles and may depict a judgment. It can be seen at Gravensteen, a building that served as a prison between 1463 and 1955. This historical building later became…
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Key publications
Key publications of the Quantitative Pharmacology group
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Kloosterman professors
List of Kloosterman professors
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X Anniversary Convention of the Centre of Austrian Studies in November 2016 in Jerusalem
Impressions by Martin Küster, Master of Arts.
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Drug-target binding kinetics in vivo
A next, general pharmacological problem to be tackled is how drug-target binding kinetics in vivo, affects target occupancy as an important indicator of the time-course of drug effects.
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Accessing End-Of-Supply Risk of Spare Parts Using Big Data
How to access the end-of-supply risk of spare pares using big data analytics