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Awarded research project Next Generation ImmunoDermatology: Towards Biomarker-driven Dermatology practice in the Netherlands

The Dutch Research Council (NWO) has, within the framework of Research along Routes by Consortia (NWA-ORC), awarded the research project Next Generation Immuno-Dermatology (NGID) with a prestigious grant of 11.7 MEuro. NGID is a nationwide, large-scale project to unravel novel biomarkers for six different skin diseases. These biomarkers will drive a high-tech, patient-centric approach in clinical practice. Prof. Robert Rissmann, (Leiden Academic Centre for Drug Research, Leiden University / CHDR) is the coordinator of the NGID Project.

In the Netherlands over 2.5 million patients suffer from chronic inflammatory skin diseases. Although not life-threatening, the personal impact and socio-economic costs of these chronic conditions are very high. The biggest problem is that many treatments are not suited for every patient and often do not work.

NGID will tackle this problem and will develop the right care for the right patient at the right time. Within this 6-year project six inflammatory skin diseases will be investigated in ultra-high detail. For this approach, a unique, international consortium consisting of scientific institutes, universities, high-tech companies, hospitals, patient associations and (bio)pharmaceutical industry has been setup. Dermatologists from all Dutch University Medical Centers will be connected to biologists, bio-informaticians, statisticians, behavioural scientists, communication researchers and of course to the patient. By means of a new data analysis and integration approach, NGID will make patient-specific fingerprints that will guide the best care for the individual patient in the future.

Patient statement. Ilse van Ee (Dutch psoriasis patient association): “For many patients it is a long quest to find an effective and good treatment. The NGID should enable a more rational and targeted treatment of skin diseases. I expect a big impact on Dutch patient care in dermatology”.

Prof. Robert Rissmann (Leiden Academic Centre for Drug Research, Leiden University) will be fulfilling the coordinating role for this project. The following investigators will be participating: Prof. Hankemeier (LACDR – metabolomics), Prof. Bouwstra (LACDR - lipidmomics), Prof. Evers and Dr van Beugen (FSW – behavioural and psychological markers), Prof. Lelieveldt (LUMC and TU Delft, data visualisation and data integration), Prof. Koning (LUMC - immunology and spatial omics), prof. Huizinga (LUMC – rheumatology), Prof. Vermeer (LUMC – clinical dermatology) and Dr. El Ghalbzouri (LUMC – translational dermatology), Dr. Lindenburg and Dr. Kaal (Hogeschool Leiden - metabolomics) and Dr. Exadaktylos (CHDR – remote trials).

Project Facts

Project acronym:          NGID

Project title:                     Next Generation ImmunoDermatology

Start date:                         1 Sep 2022

Duration:                           72 months

Budget:                                € 11.7 M

Coordination:                   Leiden University, Prof. dr. R. Rissmann

Project Management:    Maastricht University


Almirall (NL/ Spanje)

Amsterdam Universitair Medische Centra

BIOMAP consortium, EU IMI2

CELLnTEC (Zwitserland),

Centre for Human Drug Research

Clinical Microbiomics (Denemarken)

Erasmus MC

FibroTx (Estland)

Hogeschool Arnhem Nijmegen -  University of Applied Sciences

Hogeschool Leiden

Huid Nederland

Janssen-Cilag B.V.

Leids Universitair Medisch Centrum

Maastricht University

Maastricht University Medical Center

Maruho (Japan)

Nederlandse Vereniging voor Dermatologie en Venereologie

Nederlandse Vereniging voor Experimentele Dermatologie

Perimed AB (Zweden)


Psoriasispatiënten Nederland

Radboud Universitair Medisch Centrum

River Diagnostics


Scibase (Zweden)

Skin Research Institute of Singapore, Innovative Medicines Initiative

Stichting Huidlymfoom,

Technische Universiteit Delft

Universitair Medisch Centrum Groningen

Universitair Medisch Centrum Utrecht

Universiteit van Amsterdam

Universiteit Leiden

Vereniging voor Mensen met Constitutioneel Eczeem

Contact for press

Prof. Robert Rissmann, Leiden University

Coordinator NGID Project

Leiden Academic Centre for Drug Research


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