1,630 search results for “predictive modeling” in the Public website
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A mathematical model for a more diverse workforce
Many organisations have a biased workforce, even though diversity has so many advantages. Australian and Dutch researchers, including Leiden psychologist Romy van der Lee, have developed a solution based on a mathematical model. They published their findings in PLoS One on 28 July.
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Identification of novel targets in prostate cancer progression
Promotor: Prof.dr. B. van de Water, Co-promotor: E.H.J. Danen
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High-throughput simulation studies of angiogenesis - Reverse engineering the role of tip cells and pericytes in vascular development
Promotor: Prof.dr. R.M.H. Merks
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Development of a consistent methodology for assessment of the combined effects of metal-based chemicals to lettuce (Lactuca sativa L.)
How to improve the method in quantifying the combined effects of metal-based chemicals?
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Long term dynamics of stochastic evolution equations
Promotor: S.M. Verduyn Lunel, Co-promotor: O. van Gaans
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Staying Ahead of the Virus
In STAYAHEAD data-intensive approaches are being developed to ”decode the human immunome” with a focus on a global vaccine strategy. They have developed a rapid mass spectrometric test to analyse in real-time large numbers of variants of SARS-CoV-2 and the host immune response, and use these data to…
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Transforming data into knowledge for intelligent decision-making in early drug discovery
Promotor: A.P.IJzerman Co-promotor: A. Bender
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Pasteurs Cube: a new model for classifying academic researchers?
Applying a three-dimensional framework of research-related activities, Pasteur’s Cube helps to describe and study ‘use inspired’ academics at today’s research-intensive universities.
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Intracellular allosteric modulators for human CC chemokine receptors
Supervisor: Natalia Ortiz Zacarías
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Monitoring the development of foster children
Foster children’s behaviour is more problematic than that of their peers in ‘normal’ family situations. However, it is difficult to determine the exact cause of behavioural problems. Anouk Goemans, a researcher in clinical child and adolescent studies, calls for more screening and monitoring. PhD defence…
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Virtual children help prevent withdrawal syndrome in real children
When children wean off from heavy medication, they often experience withdrawal symptoms. The severity of these symptoms is often difficult to predict. Pharmacologist Bas Goulooze developed a computer model to determine the best weaning strategy for each child. His research has now been published in…
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How do children's kidneys eliminate drugs?
What dose of medicine do you give a child? That depends to a large extent on how quickly their kidneys remove the drug from the blood. For ethical reasons it is impossible to measure this directly in little patients. PhD candidate Sinziana Cristea combined different types of modelling and lots of data…
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Jose G. Vallarino
PhD at Molecular Biology and Biochemistry Department, University of Malaga - Spain
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Micha Drukker
Science
m.drukker@lacdr.leidenuniv.nl | +31 71 527 6271
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HomininSpace – a large scale simulation system for hominins in the past
HomininSpace is an agent based modelling and simulation system in which fluctuating carrying capacity is the key attractor for hominin dispersal. A parameterized and spatially explicit reconstructed palaeo-environment models available energy in the form of secondary biomass using reconstructed climate…
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Elizabeth (Liesbeth) de Lange
Science
ecmdelange@lacdr.leidenuniv.nl | +31 71 527 6330
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Smartmix: A new generation of efficient biomedical research
Can we find and commercialise new treatments for chronic disease that affect our ageing population? And how can we customise this research and development programme to the small but highly-developed Netherlands research economy?
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Quantitative Clinical Pharmacology
The Quantitative Clinical Pharmacology group is led by Prof. Dr. Catherijne Knibbe. Her research group aims to define how to adjust a drug dose in special patient populations such as (prematurely born) neonates or children, obese individuals or critically ill patients. Through combining the statistical…
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Master Projects
Master projects are available in
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Leiden Academic Centre for Drug Research
Drug development is a complex process in which many parties work together. Every day, the researchers at LACDR devote their energies to developing drugs that are new, better, more efficient and easier to produce. And thus to the millions of patients who know all too well why this research in Leiden…
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Quantitative pharmacology of antimicrobials
Antimicrobial drugs constitute a fundamental part of modern medicine. The global rise in antimicrobial resistance poses a major threat to global health.
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Software and data for circular economy assessment
This thesis investigates how the assessment of circular economy (CE) at the macro-economic level can be facilitated and promoted.
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Hunting for the fastest stars in the Milky Way
The high velocity tail of the total velocity distribution of stars provides essential insight into fundamental properties of the Galaxy.
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Gibbs processes and applications
Gibbs processes, g-measures, fuzzy Gibbs states
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About the programme
PHM offers you the tools to navigate through, and give direction to, the complex and changing health care landscape by using an interdisciplinary approach. Become the broker to improve health and societal outcomes for citizens and patients.
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Sybil-AA: Systems Biology of Alcohol Addiction
The Horizon 2020 project Sybil-AA (Systems Biology of Alcohol Addiction) focuses on modeling and validating disease state networks in human and animal brains for understanding pathophysiology, predicting outcomes and improving therapy in alcohol addiction. Alcohol addiction, the most severe form of…
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New publication by Christa Tobler on alternative models of EU integration
Following the conference of the 20th Austrian European Law Day in September 2021 at the University of Liechtenstein in Vaduz, the academic papers of the conference have now been published in book form. The book contributions include a chapter by Christa Tobler: Christa Tobler, 'Finally Brexit - Alternative…
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Database full of 3D models: 'Maybe it will help us deal with restitution more inclusively'
Scientists' computers are now full of complicated 3D models, but no standard has yet been developed for exchanging the data. A new database should change this. External PhD student Liselore Tissen is receiving a grant to contribute to this on behalf of Leiden University (and TU Delft). ‘It will be great…
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The integration of meta-analysis and classification & regression trees: meta-CART
In meta-analysis, heterogeneity often exists between studies. In such cases, it is essential to investigate the sources of heterogeneity and understand the relationship between effect size and study characteristics (i.e., moderators).
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Marco Spruit wants to develop a language model to improve healthcare
By making smart use of available data, the health and care of people can be substantially improved. Marco Spruit wants to use language and machine learning in the coming years to identify and solve the biggest care issues in the region of The Hague. He has been appointed Professor of Advanced Data Science…
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Galaxy formation and the structure of the Universe
Promotores: Prof.dr. J. Schaye, Prof.dr. S.D.M. White (MPA Garching)
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Guiding evolutionary search towards innovative solutions
Promotors: Prof.dr. T.H.W. Bäck, Prof.dr. B. Sendhoff (Technische Universität Darmstadt)
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PI3K signaling and adherens junctions in invasive lobular breast cancer
Invasive lobular carcinoma (ILC) is the second most common type of breast cancer.
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Quantifying the toxicity of mixtures of metals and metal-based nanoparticles to higher plants
Promotores: Prof.dr. W.J.G.M. Peijnenburg & Dr. M.G. Vijver
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dr. ir. Hai-Xiang Lin working on Data Analytics for Environmental Modelling joins CML
Prof.dr.ir. Hai-Xiang Lin is appointed on 1 March 2015 as part-time professor on Data Analytics for Environmental Modelling at CML on behalf of the R. Timman foundation. He will join the CML-department of Industrial Ecology. He has a position at the Department of Applied Mathematics at the Faculty…
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New professor Suzan Verberne aims to bring large language models and search engines closer together
Suzan Verberne has been appointed professor of Natural Language Processing at the Leiden Institute of Advanced Computer Science (LIACS) from 1 October. Verberne has been at LIACS since 2017 as group leader of the Text Mining and Retrieval group.
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Plant BioDynamics Laboratory
The Plant BioDynamics Lab (PBDL) is a laboratory dedicated to experiments designed to develop and validate quantitative mathematical models of dynamical processes in biology. The principal objective of developing these models is to make quantitative predictions about these processes.
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Probing new physics in the laboratory and in space
The Standard Model (SM) of particle physics fails to explain several observed phenomena and is incomplete. In order to resolve this problem, one may extend the SM by adding new particles.
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Cheminformatics: Analyzing small-molecule activity data
While bioinformatics methods deal with the analysis of sequence information (be it proteins or DNA), the field of cheminformatics is concerned with the analysis of small-molecule datasets.
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Fermions and Bosons: Excitons in strongly correlated materials
Promotors: Prof.dr. J. Zaanen, Prof.dr.ir. H. Hilgenkamp
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Joost Beltman
Science
j.b.beltman@lacdr.leidenuniv.nl | +31 71 527 4323
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Advances in Survival Analysis and Optimal Scaling Methods
This thesis is based on five papers on several topics.
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Leiden University wins best position paper at the 2019 Model ICAO
The 2019 Model ICAO took place from 21-24 May at the ICAO headquarters in Montreal.
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Using statistics to prevent the loss of blood donors
The Sanquin blood bank gathers data on every donation. Around 720,000 donations are made every year. ‘That generates a mountain of highly valuable data,’ says Leiden PhD candidate Marieke Vinkenoog.
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Software development by abstract behavioural specification
The development process of any software has become extremely important not just in the IT industry, but in almost every business or domain of research.
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MULTIPLY - MULTIscale SENTINEL land surface information retrieval Platform
Aim: To develop and enable application of a practical, flexible, user-friendly platform to provide the scientific community with a tool to generate land surface products and its associated uncertainties and exploit these for data-intensive science.
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Health Data Science
Health research, medical practice and consequently the whole population is increasingly affected by digitization, data science and AI.
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Bamboo
Biodiversity and trade: mitigating the impacts of non-food biomass global supply chains.
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Hai Lin
Science
h.x.lin@cml.leidenuniv.nl | +31 71 527 7460
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Jeshua Tromp
Faculteit der Sociale Wetenschappen
j.j.tromp@fsw.leidenuniv.nl | +31 71 527 2727