1,035 search results for “global gene regulation” in the Public website
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PhD-vacancy at the IBL on the neurogenomics of vocal learning
This project on the role of FoxPs in vocal perception and production learning is part of nine PhD-positions funded by the NWO Gravitation Programme which was granted to the Dutch Research Consortium 'Language in Interaction'
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DNA folded in compliant helix
In an Advance Online Publication biophysicist John van Noort and others show using magnetic tweezers that DNA is folded in compliant helices of chromatin. This allows enzymes access to the DNA needed for gene expression. Van Noort's research group made the discovery in close partnership with researchers…
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NEXUS1492 study on ancient human microbiomes published in Nature Scientific Reports
An international team of researchers, involving members from the ERC Synergy project NEXUS 1492 based at the Leiden University, the Universities of Oklahoma, Copenhagen and York reveal challenges when studying ancient microbiomes in a recent issue of Scientific Reports.
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Planetary Thinking in the Era of Global Warming
Inaugural lecture
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Una Europa webinar: Building Global Networks through Heritage
Webinar
- GTGC Conference 2024: Emerging Trends in Global Governance
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German beyond its native speakers: pluricentric, multilingual, and globalized perspectives
Lecture, Lunch Time Talk
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Hunt for fundamental insight into and treatment for cancer
To develop good cancer treatments, we need to know much more about how malignant tumour cells develop. Professor Ewa Snaar-Jagalska looks at not just the effect of medication on isolated cells but also the behaviour of cancer cells in their tissue environment. Inaugural lecture on 11 December.
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Movements of steroid receptors inside the cell nucleus unraveled
Advanced fluorescence microscopy techniques have revealed how steroid receptors move inside the nucleus. The results were published by a team from Leiden University and the Erasmus Medical Center in Rotterdam, led by IBL-researcher Marcel Schaaf.
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Leiden scientists map cell types in fetal kidney
Kidney failure is a serious issue because kidneys cannot regenerate themselves after injury. A possible solution consists of artificially growing healthy kidney tissue. To achieve that, scientists first need to understand kidney development during the earliest stages, in the fetus. Leiden researchers…
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Ann Stoler Leiden GLASS
Professor Ann Laura Stoler from The New School for Social Research in New York will be the Spring 2016 Global Asia Scholar. She will visit Leiden University from May 17-19, 2016.
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Theory
Many important topics in computer science, such as the correctness of software, the efficiency of algorithms and the modeling of complicated systems, depend on sound theoretical underpinnings. In the Theory group, we study these fundamental building blocks and develop verification methods to prove system…
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Biomolecular analyses of skeletal remains in the circum-Caribbean across the historical divide (A.D. 1000-1800)
As part of the NEXUS1492 project, this project will use ancient DNA techniques to shed new light on the demographic and health history of the Caribbean and the impact of European colonization on indigenous communities in the region.
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Research
The current projects of the Molecular Physiology group focus on proteins of the endocannabinoid system, kinases and antibacterial targets. MSc- and BSc-students can contact Jessica van Krimpen-Kraaijenoord to apply for research internships.
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Using zebrafish to target the Achilles’ heel of cancer
Exploiting metabolic vulnerabilities to identify anticancer compounds in zebrafish synthetic lethality screens.
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Theory
Many important topics in computer science, such as the correctness of software, the efficiency of algorithms and the modeling of complicated systems, depend on sound theoretical underpinnings. In the Theory group, we study these fundamental building blocks and develop verification methods to prove system…
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Awards and Grants 2022
An overview of awards and prizes granted to our staff and students in 2022, as well as special appointments at Leiden University and other institutions.
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Research
Research at the Macromolecular Biochemistry group is comprised of the following research themes:
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United States
This is an Erasmus+ International Credit Mobility project of Leiden University Medical Center with Boston Children’s Hospital in the USA.
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Research lines
Physics and Engineering Approaches to Biomedicine and Pharmacology
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Physics and Engineering Approaches to Biomedicine and Pharmacology
Mashaghi lab conducts research at the interface of physics, engineering and biomedicine. We develop and use theoretical and experimental approaches to address basic and applied research problems.
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Formulation and Characterization of Vaccines
Vaccines are an extraordinary category of biopharmaceuticals. They are usually prophylactic and come in many types, from whole bacteria to peptides and nucleic acids. They are very cost effective and almost every human on the planet is vaccinated. The latter mandates that vaccines have to be extremely…
- About this minor
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Statistics & Data Science (MSc)
The master’s programme Statistics & Data Science provides students with a thorough introduction to the general philosophy and methodology of statistical modelling and data analysis. The programme has two specialisations: Data Science and Statistical Science.
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Vision and Mission
The need for novel drugs as well as innovations in their development and application is as urgent as ever. Below we present our vision , mission, and our key research areas.
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Cancer Therapeutics and Drug Safety
In this research group, headed by Bob Van de Water, cell signaling programs that underlie adverse drug reactions as well as cancer development and progression are unraveled. Adverse drug reactions involve cell injury in critical target organ cells which leads to the activation of cellular stress response…
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Image-based Computational Biology
In this research group, led by Dr. Joost Beltman, the aim is to employ mathematical and computational dynamical modelling approaches in order to quantitatively and mechanistically understand the dynamical behaviour and regulation of intracellular networks of genes, proteins and metabolites as well as…
- Research Dossiers
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Bente de Leede
Faculty of Humanities
b.m.de.leede@hum.leidenuniv.nl | +31 71 527 1646
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Maritime Conflict Management in Atlantic Europe, 1200-1600
What can we learn from how maritime conflicts were managed in the past? What significance did Maritime Conflict Management have in shaping the standards of diplomacy and international law in pre-modern Atlantic Europe (1200-1600)?
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Unstoppable urbanisation of Indonesia calls for interdisciplinary partnerships
More than half of the Indonesian population lives in cities. What does this mean for public health? How sustainable are these megacities? This is the subject of the ‘Urban Transitions’ Summer Academy on West Java. This summer course is also the kick-off for a renewed interdisciplinary partnership…
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New impulse for autism research in collaboration with China
Psychologists of Leiden University and Peking University will collaborate to investigate the deficiencies in emotion recognition in children with Autism Spectrum Disorder (ASD). The new collaboration fits very well in the policy of Leiden University in which intensified collaboration with China has…
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GTGC conference on the pressing social issues of our time
Major developments worldwide are creating new challenges for society. The pandemic has hit us hard, for example, and we are already feeling the effects of global warming. How can society and politics deal with the urgent problems of our time? That is the theme of the Global Transformations and Governance…
- GTGC lunch seminar: Eve Darian-Smith and Phil McCarty on Global Studies Methods
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Veni awards for seventeen young Leiden researches
The Netherlands Organisation for Scientific Research (NWO) has awarded Veni funding to seventeen researchers who recently obtained their PhD. This award offers promising young scientists the opportunity to develop their own ideas over a period of three years.
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Summer school 'Socioeconomic diplomacy and global empire building, 16th-19th centuries'
Conference, Summer School
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ERC Consolidator Grants for Leiden researchers
Five Leiden researchers have been awarded a Consolidator Grant by the European Research Council (ERC). This grant of up to two million euros will enable them to continue and expand their scientific research.
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LUMC signs international agreement on developing Advanced Therapy Medicinal Products
Skåne University Hospital, Lund University and Leiden University Medical Center will work together to expand their research, teaching and development relating to Advanced Therapy Medicinal Products. That is the essence of a Memorandum of Understanding signed at SciLifeLab near Stockholm on Wednesday…
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Roundtable: Is the Russia-Ukraine War a Global War? / Workshop: Archives and Methods
Conference, INVISIHIST Pre-Conference
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New cell therapy facility at Leiden Bio Science Park
American pharmaceutical company Bristol Myers Squibb will be building a new (CAR-T) cell therapy facility in the Oegstgeest part of the Leiden Bio Science Park. The company will manufacture and develop CAR T-cell therapy for patients with blood cancer (leukaemia), for example.
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Matching medication to DNA leads to 30% fewer side effects
According to the LUMC, patients experience 30% fewer serious side effects when medication doses are tailored to their DNA.
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First clinical trial with genetically modified malaria vaccine completed
In an innovative study, Radboudumc and LUMC jointly tested a candidate vaccine based on a genetically weakened malaria parasite. The results of this clinical trial, published in Science Translational Medicine, show that the vaccine is safe and elicits a defense response against a malaria infection.
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New insights for improved pertussis vaccines - Press release -
Researchers in Bilthoven, The Netherlands, have recently unraveled the defense against whooping cough bacteria in unprecedented detail. The outcome of the project, conducted at Intravacc (Institute for Translational Vaccinology) in Bilthoven, provides opportunities for a new approach in the development…
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King of Sweden visits Leiden University
Collaborating in drug discovery and health research was the goal of a visit to the Leiden Bio Science Park on 14 May by a Swedish delegation including His Majesty King Carl XVI Gustav of Sweden. The delegation visited Leiden University’s Faculty of Science.
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GI grants awarded to Mariana Francozo, Sabine Luning and Wayne Modest
Global Interactions is pleased to announce that we have awarded a GI Advanced Seminar grant to Dr. Mariana Francozo (Archaeology) for 'Historia Naturalis Brasiliae' and a Breed Grant for 'Global Earth Matters' to Dr. Sabine Luning (CA-DS) and Dr. Wayne Modest (RCMC)
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to the Wanghong Restaurant…”: Following the wanghong as an aspect of global China
Lecture, LIAS Lunch Talk Series
- Opening Lecture Owada Chair: Global Diversity and the Living International Human Rights Law
- Master's Online Experience Day Colonial and Global History: Online Q&A
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Alternative? Examining the Emerging Role of Chinese NGOs in China's Global Development Footprint
Lecture, Lunch Research Seminar
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Snake genomes revealed for King Cobra and Burmese Python
Freek Vonk and Mike Richardson, with many collaborators, have published two snake genomes in two parallel articles in the prestigious journal PNAS. Their new findings provide insight into the co-evolutionary arms race between predator and prey.