Researchers from Leiden University Medical Center (LUMC) and the Leiden-based biotech company Ncardia have joined forces to develop a new platform that enables the automated production of 3D cardiac microtissues. This platform will allow large numbers of drugs to be tested quickly

Digital diagnostic tools should improve the diagnostic process of patients with musculoskeletal complaints, so that they can receive the right treatment more quickly.

Infecting each other with viruses and bacteria while protecting yourself with medicines and vaccinations. Sounds like a fun evening, right? Master students Life Science & Technology Rafael Jezior and Dennis de Beeld certainly think so. Together, they developed ImmunoWars: an exciting card game based…

Immunologist Leender Trouw specialises in the complement system, which is part of the immune system. In some diseases drugs help activate or inhibit this system. This is best done ‘in the right place at the right time’ − the title of his inaugural lecture.

Researchers from Leiden Law School and the LUMC have received a grant for a joint research project. They will be looking into ways in which caregivers and patients can work together to come to a better decision.

Leiden University Medical Center (LUMC), as a partner in the reNEW consortium, is once again receiving tens of millions of euros for research into new treatments based on stem cells. The collaboration will receive a total of €150 million to develop new therapies in regenerative medicine.

In brain diseases such as Parkinson's and Alzheimer's, proteins clump together to form fibres. ‘Chaperone proteins’ unravel those fibres, but in the test tube biochemist Anne Wentink saw that this can also cause new problems. She is going to find out what happens inside cells to determine what a drug…

Cognitive decline and anxiety in Parkinson’s disease are often only recognised at a late stage, in spite of their great impact. Research by Marit Ruitenberg focuses on new tests and methods to show up these symptoms earlier and make them more specific.

Erection problems can have a huge impact on quality of life and health, but current diagnostic methods are painful, uncomfortable and technologically outdated. PhD candidate Evelien Trip has developed a new device that can measure erections more comfortably and painlessly.

The importance of a healthy lifestyle does not receive the attention it deserves, as the coronavirus pandemic made painfully clear. Twelve behavioural scientists, including Professor Behavioral Interventions in Population Health Management Marieke Adriaanse and Professor of Health Psychology Andrea…

Charlotte Poot (31) is co-founder and chair of Hospital Hero, an app that prepares children for a hospital visit. She studied and obtained her PhD at the LUMC.

Inaugural lecture

Tuberculosis stands as one of the most lethal infectious diseases worldwide. A significant challenge in combatting tuberculosis lies in the emergence of antibiotic resistance triggered by genetic alterations, commonly known as mutations. These mutations can diminish the responsiveness to antibiotics,…

Mini organs-on-chips allow us to study how diseases develop and how drugs work. Although the technology is not new, it is becoming increasingly advanced. PhD candidate Bart Kramer hopes it will eliminate animal testing in the future.

There seem to be genes that influence how our brains develop over time. A large international consortium has discovered this with an extensive study. The results of the study were recently published in Nature Neuroscience.

PhD defence

PhD defence

The Royal Netherlands Academy of Arts and Sciences (KNAW) has elected 16 new members, including two academics from Leiden: internist-infectiologist Meta Roestenberg and Arabist Petra Sijpesteijn.

A team of students from Leiden won the iGEM international biology contest in 2020 with their Rapidemic mobile testing kit. The kit makes it easy to detect viruses. The team has now been nominated for the Most Innovative Student in the Netherlands prize. Cast your vote and help them develop their inv…

The AtheroNeth consortium received €6 million from the Dutch Heart Foundation to gain a better understanding of the differences in disease progression among patients with atherosclerosis. The ultimate goal is to enable personalised treatment.

Suddenly getting lost, failing to recognise family members, or forgetting words and names are well-known symptoms of Alzheimer's disease. Psychologists have now discovered that the disease also manifests in more subtle ways: through the rhythm of finger tapping.

Martina Huber, Jacqueline Labra Munoz research Alzheimer's disease. They study ferritine, iron storage in the brain. An inbalance of iron could play a role in this form of dementia.

Before patients can take a pill, scientists often spend years in the lab developing and testing a candidate drug. That often includes experiments with laboratory animals. As head of the rodent facility, Ilze Bot and her colleagues ensure that these experiments are conducted in an ethically responsible…