1,826 search results for “brain development” in the Public website
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Does the human brain process angry voices automatically?
Using brain imaging to discover the area in the brain that recognizes emotion.
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Prediction of spatial-temporal brain drug distribution with a novel mathematical model
A novel mathematical model describes spatial-temporal drug distribution within one or more brain units, which are cubic representations of a piece of brain tissue with brain capillaries at the edges.
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Lina van Drunen
Faculteit der Sociale Wetenschappen
l.van.drunen@fsw.leidenuniv.nl | +31 71 527 2727
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Towards High Performance and Efficient Brain Computer Interface Character Speller: Convolutional Neural Network based Methods
A P300-based Brain Computer Interface character speller, also known as P300 speller, has been an important communication pathway, under extensive research, for people who lose motor ability, such as patients with Amyotrophic Lateral Sclerosis or spinal-cord injury because a P300 speller allows human-beings…
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On the representation of quantity: how our brains shape language
This project investigates properties of quantity expressions across languages from the perspective of how quantity is represented in the human brain.
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The LeiCNS-PK3.0 model development and applications: healthy-to-diseased CNS pharmacokinetic translation
Accurate prediction of the unbound drug concentration-time profile at the CNS target site is crucial for the assessment of the right drug concentration-effect relationship. PBPK models have supported the PK prediction of the CNS target sites and the translation of PK data between species and between…
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XXY versus autism: evidence from neuroimaging
Brain development in children with an extra X chromosome as compared to children with autism: evidence from MRI
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Me, My Fiends, and I
A neuro-ecological perspective on adolescent prosocial development
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Ahmed Mahfouz: 'The mystery of brain diseases, unravelled cell by cell'
Which brain cell does what, when Parkinson's disease arises? It won't be long before this jigsaw is solved piece by piece. Ahmed Mahfouz, computational biologist, combines bio-knowledge from Leiden with algorithms from Delft and is getting closer to finding the key.
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Applied Neuroscience in Human Development (MSc)
Are you interested in the neurocognitive and biological roots of learning, behaviour and emotions in children? If so, the programme in Applied Neuroscience in Human Development might be the specialisation you are looking for.
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Serge Rombouts: 'AI is learning from brain scans and helping find a diagnosis'
Serge Rombouts is a physicist whose PhD thesis was about functional MRI (fMRI). This visualises activity in regions of the brain. The appealing images of glowing brain regions that emerge from the computer are the result of calculations. According to Rombouts, this isn’t proper artificial intelligence.…
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How to keep your brain healthy? Scientists provide tips at brain festival
At science festival 'Over de kop', surprising brain facts alternate with confronting stories from the operating room. Researchers explain why our brains love beans and why you should never ride a racing bike without a helmet.
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Research
Central elements in the research activities of all programme group members are: attachment, sensitive caregiving, and prevention and intervention.
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Back to the scanner: brain science in times of corona
For their research many neuropsychologists use the brain scanners at the LUMC. At the start of the pandemic, the rules for visiting the hospital became stricter and a large amount of psychology research looked as though it would fall through. Thanks to good protocols the researchers can now pick up…
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Like me or else...
Nature, nurture and neural mechanisms of social emotion regulation in childhood
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Rapid and profound rewiring of brain lipid signaling networks by acute diacylglycerol lipase inhibition
Diacylglycerol lipases (DAGLα and DAGLβ) convert diacylglycerol to the endocannabinoid 2-arachidonoylglycerol. Our understanding of DAGL function has been hindered by a lack of chemical probes that can perturb these enzymes in vivo.
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Pregnancy changes brain structure
Brain researcher Elseline Hoekzema has discovered that the structure of the brain changes during pregnancy, particularly those areas related to social functions. These changes persist for at least two years after the mother gives birth. Publication in Nature Neuroscience on 19 December.
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Why more women have ADHD than you think
When we think of ADHD, we often think of highly creative, hyperactive boys. But does this mean that girls don’t have ADHD at all?
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Berna Güroglu
Faculteit der Sociale Wetenschappen
bguroglu@fsw.leidenuniv.nl | +31 71 527 2727
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the road to optimize rehabilitation for young people with acquired brain injury
PhD defence
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Neurolinguists investigate the brain: not two, but three options for brain functional categories
Based on the results of a language-switching experiment, PhD candidate Fatemeh (Simeen) Tabassi Mofrad MA and Professor Niels Schiller have discovered that the traditional categorisation of brain areas is not sufficient. They published their research findings in the scientific journal NeuroImage.
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Brain activity of popular adolescents measured
Adolescents who were more popular among their classmates in junior school are often the ones who are more inclined to share things fairly with others. During this sharing process, 'social' areas of the brain are more strongly activated than in adolescents who are less popular. This is the finding of…
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physical activity wearable data and its relation with metabolic and brain health in older adults
Quantifying physical activity (using accelerometers) and combining the frequency and intensity of activities with health data (brain MRI, traditional clinical parameters and metabolomics) is of utmost importance to monitor mobility and health among older individuals and study health promotion during…
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How harmful is alcohol for the adolescent brain?
Under 18, no alcohol. In spite of this slogan, adolescents still have access to alcohol. But how harmful is that one beer for the adolescent brain? Research, including in Leiden, may provide the answer.
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A different take on differences between men’s and women’s brains
There is greater variety in the size of men’s brains than of women’s. This could help explain why some psychiatric disorders such as ADHD and autism are more prevalent in boys. Leiden brain researcher Lara Wierenga has published an article about this in the international journal Cerebral Cortex.
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BRAIN appoints University of Leiden as partner for BEC-Enabled production strain development
BRAIN Biotech and the Leiden University will jointly develop an Aspergillus based production strain with high yield and thus contribute to a bio-based circular economy. The cooperation is based on BRAIN´s molecular tool BEC.
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Brains react differently to ADHD medication than expected
A tried and tested medication for treating ADHD works differently than expected in the brains of healthy individuals during rest: rather than stimulating brain activity, it suppresses it.
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New substances inhibit inflammation in the brain
Chemical biologists from Leiden, led by Dr Mario van der Stelt, have discovered substances that can reduce inflammation processes in the brain. This is a first step in the development of potential medicines for the treatment of brain diseases like Alzheimer's and Parkinson's. Published in Proceedings…
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The adolescent brain makes learning easier
The brains of adolescents react more responsively to receiving rewards. This can lead to risky behaviour, but, according to Leiden University research, it also has a positive function: it makes learning easier. Publication in Nature Communications.
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Are the brains of males different from those of females? Psychologists produce a podcast on brain research and mental health
Women are more often diagnosed with depression, whereas ADHD is much more frequently detected in men. And there are other more striking differences. What role does the brain play in mental health and what is the influence of the environment? For answers to these questions, listen to the ‘(Un)gendered…
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Drug Delivery to the Brain
This book describes the different approaches for drug delivery to the brain with an emphasis on the physiology of the blood-brain barrier (BBB) and the governing principles and concepts for drug delivery across the BBB
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Individual differences in genetic and environmental effects on brain development
PhD defence
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Functional networks in healthy and sick brains
Are disturbances to the brain, such as Alzheimer's or autism, linked to specific defects in the underlying communication networks in the brain? If this is the case, subtle changes in the networks can act as a marker for brain disturbances. Neuroscientist Serge Rombouts will be investigating this, together…
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Developmental and Educational Psychology Lab
What is the relation between brain development and social and cognitive development across childhood, adolescence and adulthood?
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Burning brain questions of young people bundled in new research agenda
During ExpeditionNEXT in Middelburg, NeurolabNL youth, together with researchers from Leiden University and Erasmus University, handed over a unique research agenda to NWO Chairman Marcel Levi. In it, young people share what they would most like to learn about themselves and the brain.
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Mathematical model predicts drug concentration in the brain
Do medicines arrive in the right amount at the right spot in our brain? By making a model that depicts our brain in small 'brain blocks', Esmée Vendel tries to find an answer to this question. Her new, mathematical model predicts the concentration of medicines in the brain over time and space. Vendel…
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Leukemia treatment & cognitive development
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Rebecca Schaefer on 'Learning with music can change brain structure'
Using musical cues to learn a physical task significantly develops an important part of the brain, according to a new study co-authored by Leiden psychologist Rebecca Schaefer. The results are published in the journal Brain & Cognition.
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ERC Consolidator Grant for Eveline Crone
Eveline Crone surmises that adolescence also has a positive effect on social development. She believes, for example, that it is in adolescence that young people learn the skills of cooperation, sharing and helpfulness. She will be researching this hypothesis in the coming period with an ERC Consolidator…
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Right brain hemisphere also important for learning a new language
Novel language learning activates different neural processes than was previously thought. A Leiden research team has discovered parallel but separate contributions from the hippocampus and Broca's area, the learning centre in the left hemisphere. The right hemisphere of the brain also seems to play…
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Social brain active in childhood already
Exclusion elicits the same response in children as in adolescents and adults. That is what psychologist Mara van der Meulen found when she studied brain activity in primary schoolchildren. ‘What is new for us is that it is the same in childhood as later in life.’ Doctoral defence on 10 December.
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Interdisciplinary approach benefits brain research
How do practice and theory reinforce one another in neuroscience? Professor Birte Forstmann’s inaugural lecture on 2 October will be about building interdisciplinary bridges between cognitive neuroscience and cognitive models. Her approach may lead to brain research with fewer side-effects for patie…
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The brain on alert
When focussing attention, the neurotransmitters noradrenaline and acetylcholine play an important role. This new finding made by psychologist Stephen Brown provides clues for further research on how focussed attention comes about. Dissertation defence on 16 June.
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Novel detection method for iron in Alzheimer’s brain
For many years, scientists have observed a correlation between Alzheimer’s disease and a surplus of iron in the brain. However, a causal link between the two has not been proven yet. We lack knowledge concerning the specific form of iron that is involved in the development of neurodegenerative diseases.…
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Interdisciplinary approach benefits brain research
How do practice and theory reinforce one another in neuroscience? Professor Birte Forstmann’s inaugural lecture on 2 October will be about building interdisciplinary bridges between cognitive neuroscience and cognitive models. Her approach may lead to brain research with fewer side-effects for patie…
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Music and the Brain
Two events on Music and the Brain will be held in Leiden later this month.
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Channeke Keuls
Faculteit der Sociale Wetenschappen
c.s.keuls@fsw.leidenuniv.nl | +31 71 527 2727
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Eveline Crone in the media
In the Dutch media lots of articles have recently appeared based on interviews with Eveline Crone about the adolescent brain.
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Genetic predisposition to social anxiety disorder measurable in the brain
It was already known that social anxiety disorder often affects more than one person in the same family. But research by PhD student Janna Marie Bas-Hoogendam has now shown that there are genetic brain characteristics that are associated with social anxiety. The PhD ceremony will take place on 14 Ja…
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Research
The main focus of our research programme is on adolescence, a key transitional period in human development. The programme puts emphasis on combined experimental behavioural and neural analysis of normative transitions and deviations in adolescent development.