3,607 search results for “development 26 disease” in the Public website
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Vivian Kraaij
Faculteit der Sociale Wetenschappen
kraaij@fsw.leidenuniv.nl | +31 71 527 3736
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Micha Drukker
Science
m.drukker@lacdr.leidenuniv.nl | +31 71 527 6271
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Martijn van der Lienden
Science
m.j.c.van.der.lienden@lic.leidenuniv.nl | +31 71 527 2727
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Video lecture: What is cancer?
Cancer is still one of the most common diseases in the world. What exactly is cancer and will we one day be able to cure everyone? In a video from the Universiteit van Nederland Noel de Miranda (Tumour Immunology, LUMC) tells you about his research on new treatments.
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Research at the Living Lab
What is the effect of pesticides, fertilizers or plastic on water quality? And how do wind and rain affect the data? These are just some of the things that Leiden environmental scientists study in the 32 ditches of the Living Lab.
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Taking care of your health
Health is a wonderful gift, both for humans and for society. If we are able to prevent both physical and mental illnesses, we can spare a lot of suffering and fight rising health costs. Social scientists and physicians in Leiden are working closely together to conduct research on the human mental, behavioural…
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Animal sciences and health
In the research theme ‘Animal Sciences and Health’, we work with various animal species to gain insights into fundamental biological processes in both animals and humans.
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Hit and Lead Optimization
The goal of hit and lead optimization is to optimize suitable chemical starting points that can modulate a drug target. The methods and technologies used are similar to those in Hit Discovery, but once the compound has shown activity in an animal model, it moves from 'hit' to 'lead.'
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‘Ultimately, the goal is to develop antibiotics for tuberculosis with a lower risk of resistance’
Tuberculosis stands as one of the most lethal infectious diseases worldwide. A significant challenge in combatting tuberculosis lies in the emergence of antibiotic resistance triggered by genetic alterations, commonly known as mutations. These mutations can diminish the responsiveness to antibiotics,…
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A unique defence: Bacteria lose cell wall in the presence of virus
Bacteria temporarily live without their cell wall if dangerous viruses are near. A remarkable feature, as the cell wall is a sturdy barrier against threats. Still, the discovery has a logical explanation ánd might be of a consequence for fighting pathogenic bacteria, according to Véronique Ongenae,…
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The rise of a capital: on the development of al-Fusṭāṭ‘s relationship with its hinterland, 18/639-132/750
This thesis studies the relationship of the town al-Fusṭāṭ, located at the southern end of the Nile delta in Egypt, and its hinterland in the period between the town’s foundation in A.D. 641 and the arrival of the Abbasids in 750.
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Java: the role of indigenous institutions in integrated elderly care development in Indonesia
This research delves into the unique cultural approach of the Tenggerese people, an Indigenous community in East Java, Indonesia, regarding elderly care. It focuses on their traditional practices of bakti (‘filial piety’) and sayan (‘mutual aid’), deeply ingrained in the community's lifestyle and va…
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Translating science into treatments of rare metabolic disorders
Leiden biotech startup Azafaros has successfully completed a funding round, raising 25 million euros of investments for developing treatments of rare metabolic disorders. The company holds exclusive license to a library of novel patented compounds discovered by experts from Leiden University.
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Advanced echocardiographic imaging in valvular and systemic diseases
PhD defence
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Oxidative Stress in Chronic Diseases: Causal Inference from Observational Studies
PhD defence
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Government, media and citizens: Watch out for the nocebo Corona effect
We are confronted on a daily basis with news about the Corona virus and its consequences. We read alarming headlines like 'Dutch becoming increasingly anxious about Corona virus' or 'Huge fears and stress about Corona crisis'.
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First guidelines for applying placebo effect in clinical practice
It is becoming increasingly clear that the placebo effect has a great influence on medical treatment. An international, interdisciplinary team of researchers led by Professor of Health Psychology Andrea Evers from Leiden University has now written a first set of guidelines on how to apply the placebo…
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Cool Little Kids
Cool Little Kids is a research project that investigates the effectiveness of two programmes on the prevention and reduction of anxiety problems in shy and withdrawn children aged 2-6 years. For more information about the project please visit our Dutch website or contact us via clk@fsw.leidenuniv.n…
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Reduced stratum corneum lipid chain length relates to an impaired skin barrier function in patients with atopic dermatitis
Source: British Journal of Dermatology, Volume 170, Number 6, pp. E18-E19 (2014) ISBN:0007-0963
- Environmental Diplomacy
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All-gender toilet P.J. Veth
P.J. Veth, Nonnensteeg 1-3, 2311 VJ, Leiden
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Crossing boundaries
Celebrating 20 years of environmental research in Cagayan Valley and Sierra Madre
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Psychophysiological responses to stress and stress management
The major aim is to determine the psychophysiological responses to stress and stress-management interventions and to examine the role of stress and stress-related psychophysiological mechanisms (e.g., cognitions, behaviors, and physiological stress responses) in both healthy and medical populations.
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Hauke Ward
Science
h.ward@cml.leidenuniv.nl | +31 71 527 6808
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Nico Schrijver
Faculteit Rechtsgeleerdheid
n.j.schrijver@law.leidenuniv.nl | +31 71 527 2727
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Berna Güroglu
Faculteit der Sociale Wetenschappen
bguroglu@fsw.leidenuniv.nl | +31 71 527 2727
- Cell Observatory
- Facilities
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Bioinformatics (BSc - Biology)
Research on heredity and diseases is simply not possible without programmers. Curious about how you can use your IT and biology skills to deal with real-life sickness and health problems? If so, Bio-Informatics in Leiden could be something for you.
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Bio-Pharmaceutical Sciences (BSc)
As a student of Bio-Pharmaceutical Sciences, you have a strong interest in drug development: from the onset of diseases to the effects of individual drugs in the body. Is that true for you? Then, Bio-Pharmaceutical Sciences might be the right study programme for you!
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Unspinning chromatin: molecular mechanisms of chromatin remodeling
How do you fit two meters of DNA in a tiny compartment and at the same time are able to access the right parts of it at the right times?
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Cannabinoid receptor 2 as a ‘drugable’ target: kinetic profile of novel receptor ligands
Supervisor: Andrea Martella
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The Netherlands X-omics Initiative
The Netherlands X-omics Initiative is a new facility as part of the National Roadmap for Large-Scale Research Infrastructures. It is partly funded by NWO with a total budget of 40 million euro. The project started on September 2018 and will last for ten years.
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A much-needed new class of antibiotics
Antimicrobial resistance (AMR) is the phenomenon that pathogens become insensitive to the antibiotics that we use against them. A growing number of pathogens is becoming resistant, with methicillin-resistant S. aureus (MRSA) as the most famous example. But while the threat of AMR represents a slow-moving…
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Single cell technologies for mechanobiology and mechanopharmacology
Mechanobiology is a major area in biology, however, mechanics is currently a missing element in drug development pipelines. This has led to a high cost for the society. Mechanotoxicity of drugs often appears as a long-term side effect of drugs, and has led to removal of drugs from the market. Furthermore,…
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Lipid model membrane systems as a tool for unraveling the underlying factors for skin barrier dysfunction
Barrier function is the natural role of the skin. The lipid matrix present in the outermost layer of the skin, the stratum corneum is important for this function.
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Kinetics for drug discovery – The first step towards an improved drug discovery paradigm
Supervisor: Indira Nederpelt
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Vaccination and Targeted Therapy Using Liposomes; Opportunities for Treatment of Atherosclerosis and Cancer
This thesis focuses on using liposomes in two different treatment strategies; vaccination (or immunotherapy) and delivery of a small molecule, and in two different disease models; cancer and atherosclerosis.
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Highly sensitive analysis using 3D cell culture model
A research goal for ABS is to develop miniaturized platforms for research in (stem)cell, in-vitro systems and application in clinical and preventive research. Combined with the high throughput, this development will make it possible to study the dynamics of pathogenesis in human and cellular models…
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European Energy, Environment and Health
Research on this theme addresses the systemic risks faced by European societies and affecting the quality of life of European citizens.
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Unraveling temporal processes using probabilistic graphical models
Real-life processes are characterized by dynamics involving time. Examples are walking, sleeping, disease progress in medical treatment, and events in a workflow.
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From data to models: reducing uncertainty in benefit risk assessment: application to chronic iron overload in children
M. Danhof, Co-promotor: O.E. Della Pasqua
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Outreach
The Leiden Institute of Chemistry organises and participates in several programmes for high school students and teachers.
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Mast cell-mediated immune modulation in experimental Rheumatoid Arthritis and Atherosclerosis
In this research project, we aimed to obtain more insight in the role of mast cells in the immune driven disorders rheumatoid arthritis and atherosclerosis.
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Utopia: Universal Three-dimensiOnal Passport for process Individualization in Agriculture
Agricultural foods naturally vary in their detailed internal structure. To facilitate early detection of health hazards due to contamination or disease, predict maturity and minimize wastage, it is critical to take into account the internal characteristics of each individual product, as these enable…
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Medicine/Leiden University Medical Center
We are very happy to welcome you to spend a semester or year studying or doing an internship with us at the Leiden University Medical Center. Here you will find information on your course timetables and registration.
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Evolutionary adaptability of β-lactamase: a study of inhibitor susceptibility in various model systems
β-Lactamases are enzymes that can break down β-lactam substrates, such as antibiotics, preventing the use of these antibiotics for the treatment of various infectious diseases. However, some compounds, β-lactamase inhibitors, can block these enzymes allowing for possible treatments using a combination…
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Impact and city
Leiden University and the city of The Hague are working closely together to increase the impact of our research and education in order to contribute as much as possible to the development of the city.
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Bioactive Molecules in Microbial Sciences
Microbial Sciences' contribution to the Bioactive Molecules research theme is to discover new bioactive molecules and enzymes and unravel their mechanisms of action, regulatory networks, and the (bio)synthetic pathways required for their production.
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Transcultural Health Care Utilisation in Serengeti of Tanzania: Towards Applied Ethnoscience in Public Health Management
The research provides insight into disease behavior in both rural and semi-urban areas in Serengeti in Tanzania.