347 search results for “immuniteit infectie en tolerantie” in the Public website
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Global Public Health (BSc Major of Liberal Arts and Sciences: Global Challenges)
Although the world has made tremendous progress in health, education, sanitation and hygiene, global public health challenges still exist. Disparities in health exist between and within nations as evidenced by inequalities in disease burden, mortality, nutrition and environmental well-being. How does…
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Leijten en Arenas Catalán present current research at conference on economic and social rights
On 9 and 10 November, the Institute of International and European Law of the University of Göttingen and the Minerva Center for Human Rights of the Hebrew University of Jerusalem, organized a conference called ‘Unpacking Economic and Social Rights: International and Comparative Dimensions’.
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Innate immune defence against intracellular pathogens
What are the host immune defence mechanisms that control intracellular infections and how are these subverted by pathogens?
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ZF-HEALTH - Zebrafish Regulomics for Human Health
How can zebrafish research help understanding human diseases?
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Toll-like receptor signaling in the innate immune system of zebrafish larvae
Promotor: H.P. Spaink, A.H. Meijer Co-promotor: R. Marin-Juez
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Synthetic biology and genomics platform for new-to-nature bioactive peptides
Can the venom of snakes, scorpions and other animals be sources of new antibiotics?
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Individualized dosing of aminoglycosides and glycopeptide antibiotics in (morbidly) obese patients (AMIGO)
Timely, adequate and optimal treatment of infectious diseases is essential for the survival of patients with bacterial infections (Surviving Sepsis campaign).
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Design of dissolvable microneedles for intradermal TB vaccination
Tuberculosis is an infectious disease which is spreaded through the air. It is caused by Mycobacterium tuberculosis and it led 1.7 million people to death in 2016. This mortarlity rate is concentrated in developing countries such as Indonesia, Philippines, Pakistan, and South Africa. These numbers make…
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Development & Disease in Animal Sciences
Animal Sciences’ contributions to the Development & Disease research theme include the mechanisms and evolution of embryonic development, the development of cognitive mechanisms, and animal models for understanding mechanisms of human disease.
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Bioactive Molecules in Animal Sciences
Animal Sciences’ contribution to the Bioactive Molecules research theme includes research on molecules from natural sources, such as plants, insects, and snake venom, with the aim to identify novel anti-cancer, anti-inflammatory, anti-microbial, and anti-diabetic agents.
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The right to health of the child : an analytical exploration of the international normative framework
Large numbers of children all over the world face significant health risks, such as infectious and chronic diseases, malnutrition, injuries and the consequences of natural disasters, protracted armed conflicts and poverty.
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Targeted biomolecule production for therapeutic use
We aim to develop a drug-delivery method based on the production of biomolecules directly at the target site.
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Clinical applications of (pharmaco)metabolomics
The predication of the effect (efficiency and toxicity) of a drug in a patient is very important in (i) clinical decision support and (ii) the development of novel drug treatments. We apply our technology and methods to find biomarkers for key disease pathways and toxicity in clinical studies and in…
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From methanol to medicine – Sustainable microbial production of polyketide antibiotics
Can the pink-pigmented microbe Methylobacterium extorquens be genetically engineered to convert the sustainable raw material methanol into antibiotics?
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Fast vaccine design and development based on correlates of protection (COPs) Influenza as a trendsetter
New and reemerging infectious diseases call for innovative and efficient control strategies of which fast vaccine design and development represent an important element.
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Bioengineering and biophysics of viral hemorrhagic fever
Viral hemorrhagic fever (VHF) is a group of acute diseases caused by highly infectious viruses including Ebola, Lassa, Dengue viruses. Its high mortality rate poses high risk to public health, however, studies on VHF have been hampered due to the non-availability of proper models and incomplete knowledge…
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Regulation of autophagy-related mechanisms during bacterial infection
Autophagy is a fundamental degradative process, maintaining cellular homeostasis and functions in host defense against intracellular pathogens, including mycobacteria and Salmonella.
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Bioorthogonal Labeling Tools to Study Pathogenic Intracellular Bacteria
In this thesis, bioorthogonal chemistry is combined with correlative light-electron microscopy to selectively label and study pathogenic intracellular bacteria within the host immune cell.
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Live or let die: the intracellular fate of pathogenic mycobacteria
How do mycobacteria subvert the defenses of host immune cells?
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Institute for Chemical Immunology
Overkleeft
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Modulation of leukocyte homeostasis in atherosclerosis
Promotores: Prof.dr. E.A.L. Biessen, Prof.dr. T.J.C. van Berkel
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Continuing your studies
LUC graduates have an internationally-recognised Bachelors honours degree (BA/BSc) that qualifies them to apply for competitive programmes at top research universities. Over 90% of our alumni continue their studies into a master programme.
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Promotie Jan de Vetten - In de ban van goed en fout
Jan de Vetten brengt zijn promotieonderzoek ook uit in boekvorm. ‘In de ban van goed en fout’ beschrijft voor het eerst - op basis van archiefonderzoek en interviews - op samenhangende wijze de bestrijding van de CP en CD, en ook de reactie daarop van die partijen. Waarom werden ze zo fel werden bestreden?…
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Probes for imaging and analysis of hydrolase function in Cancer, Infectious Diseases and the microbiome
Lecture
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Inflammafish: Cross-talk between inflammation and autophagy in tuberculosis
Effective host defence against tuberculosis bacteria depends on a properly balanced level of inflammation. The Inflammafish project uses zebrafish larvae to study how autophagy controls this inflammation and vice versa.
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Development & Disease
Development & Disease is one of the four research themes of the Institute of Biology Leiden.
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European Energy, Environment and Health
Research on this theme addresses the systemic risks faced by European societies and affecting the quality of life of European citizens.
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Translational Immuno-Pharmacology
The Translational Immuno-Pharmacology group works on translating the efficacy of anti-infective therapy from preclinical (e.g. in vivo) to clinical, and is led by Rob van Wijk. Infectious diseases, such as tuberculosis, are in constant need of new therapies that work better, faster, and with less risk…
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Evolutionary adaptability of β-lactamase: a study of inhibitor susceptibility in various model systems
β-Lactamases are enzymes that can break down β-lactam substrates, such as antibiotics, preventing the use of these antibiotics for the treatment of various infectious diseases. However, some compounds, β-lactamase inhibitors, can block these enzymes allowing for possible treatments using a combination…
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Bioactive Molecules in Microbial Sciences
Microbial Sciences' contribution to the Bioactive Molecules research theme is to discover new bioactive molecules and enzymes and unravel their mechanisms of action, regulatory networks, and the (bio)synthetic pathways required for their production.
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ImageInLife: Training European experts in multilevel bioimaging, analysis and modelling of vertebrate development
How can novel bioimaging technologies and vertebrate model species be used to gain a better understanding of early cellular behaviours with the ultimate goal to increase our understanding of human development and disease processes?
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Workshop CV en brief
Career and apply for jobs
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Asklepios en het zwaard
PhD defence
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Informatiemakelaar en schietschijf
PhD defence
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Schade en risico
PhD defence
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Research at the Living Lab
What is the effect of pesticides, fertilizers or plastic on water quality? And how do wind and rain affect the data? These are just some of the things that Leiden environmental scientists study in the 32 ditches of the Living Lab.
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Tweedetaalverwerving en -didactiek: natuurlijk interdisciplinair
Inaugural lecture
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Rob van Wijk
Science
r.c.van.wijk@lacdr.leidenuniv.nl | +31 71 527 4505
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Wegbereiders. Roma en Sinti in Nederland en Tsjechië over het profijt van onderwijs, 1950-2020
PhD defence
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MARBLES - Marine Biodiversity as Sustainable Resource of Disease-Suppressive Microbes and Bioprotectants for Aquaculture and Crop Diseases
To explore the potential of marine microorganisms as producers of novel antimicrobial agents and as bioprotectants in aqua- and agriculture, using an integrative, ecology-based strategy for bioprospecting.
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Imaging of biomaterial-associated inflammation and infection using zebrafish
Which immune mechanisms are involved in host defense against Staphylococcal infection?
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Leiden Early Drug Discovery & Development
Despite recent advances in medicine, many devastating disorders like cancer and cardiovascular, neurodegenerative and infectious diseases still lack effective treatments. In order to address this challenge, we, as scientists from Leiden University, joined hands in the LED3 network. LED3, for Leiden…
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Quantitative Systems Pharmacology
This research area is focused on the development and application of novel concepts and models in the emerging area of quantitative systems pharmacology (QSP).
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Novel immunomodulatory drugs for tuberculosis treatment
Can drugs that target host signaling pathways be used to eradicate antibiotic-resistant bacteria?
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Mathematical Institute
The Mathematical Institute is responsible for the research and education in mathematics and statistics at Leiden University.
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Student projects
Are you looking for a research project?
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Denk en doe mee op het Just Peace Festival in Den Haag
Den Haag is de stad van vrede en recht. Rondom deze thema’s organiseren culturele en maatschappelijke organisaties het festival. De Universiteit Leiden is nauw betrokken bij de organisatie. Universitaire medewerkers en studenten doen bijvoorbeeld mee aan de Vredesloop, Marieke Liem van het Institute…
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‘Wij academici en docenten van Security Studies kunnen direct invloed uitoefenen.'
In zijn oratie bepleit Joachim Koops dat de toekomst van Security and Global Affairs ligt in onderzoek, onderwijs en academisch bestuur.
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Universidades Privadas Independientes en Chile
PhD defence