Also in 2024, our colleagues from the Institute of Psychology were visible in the media in various ways. Check out their appearances in Dutch media, from NRC to the Podcast psychologist.

A new LUMC study has changed our understanding of how cells work. Researchers have discovered that the CFAP20 protein acts as a kind of ‘traffic controller’ on DNA. Without this protein, chaos ensues, potentially causing cancer. Their findings have been published in the prestigious journal Nature.

Gijs Zebregts had just graduated from International Studies when he was stricken with acute leukaemia. A stem cell donor brought relief. Now he is going to cycle from Florence to Rotterdam to raise money and awareness for the donor bank.

Nathaniel Martin, Professor of Biological chemistry, wondered what would happen if you take an antibiotic that has been known for 70 years and try to improve it with the latest tools of modern chemistry. Turns out it can become up to a hundred times more potent and prevent the growth of some drug-resistant…

One used 3D cell models to study colorectal cancer, while the other used machine learning for more efficient blood donation. For these achievements, Marieke Vinkenoog and Simon Christian Hansmann were awarded the Krijn Rietveld Memorial Innovation Award on Tuesday 2 September.

Four researchers from Leiden University will receive funding from arthritis foundation ReumaNederland over the next five years. This should facilitate long-term research into arthritis.

A new treatment for atherosclerosis showed promising results in isolated cells but proved to be less effective in initial animal tests. Bachelor student Biopharmaceutical Sciences Willemijn van der Heijden aimed to understand why. She investigated whether the formation of a protein layer around the…

Biophysicist Alireza Mashaghi and his collaborators are taking up the fight against muscular dystrophy: genetic disorders that cause muscle weakness. They want to inhibit the clumping of proteins that results in toxic aggregates. For this, the team receives 550,000 euros from Health Holland. The team…

No less than four Leiden research teams have been awarded a grant by NWO. On 27 July NWO honoured 21 applications in the Open Competition ENW-XL. NWO awards the grants to consortia in the exact and natural sciences who are doing unconnected fundamental research that is 'driven by curiosity'.

Fungi germinating in the lungs of patients. Doesn’t sound too nice, does it? Luckily, humans can deal with this normally, and we are able to clear the infection before anything comes to harm. However, in people with health issues, Aspergillosis can cause a lot of damage, especially if the fungus becomes…

How do you know if a drug will actually work? The Leiden-based spin-off Omivera is developing a new technology that could provide clearer answers. The young company received a seed investment from the investment fund UNIIQ to support its development.

One in two people will be diagnosed with cancer. World Cancer Day on 4 February raises awareness of the impact of this devastating disease. Leiden University is conducting various studies aimed at preventing and controlling cancer. Below are just a few examples.

Research

LUMC research has shown that women who previously had a miscarriage due to COVID-19 are not at increased risk of having another miscarriage or a stillbirth. Nor are preventive drugs needed during the pregnancy.

Psychologist Floor van Meer won the first Trial & Error Award for her research on the effect of being distracted while eating on eating behavior. This award from the Journal of Trial & Error (JOTE) honors the often underappreciated aspect of research: learning from errors. For her publication, Van Meer…

Prof. Hanneke Hulst has been appointed Scientific Director of the Institute of Psychology by the Board of the Faculty of Social and Behavioural Sciences. She will start on 1 February 2024 for a period of 3 years, succeeding Andrea Evers and interim director Serge Rombouts.

The sixth edition of the lecture series Duurzaamheid & Recht was held during the last semester. Once again, it attracted many students.

A team led by Dr. Yannick Veilleux-Lepage (Institute of Security and Global Affairs) and Joris Larik (Leiden University College The Hague) have secured research funding from the Canadian Department of National Defence and Canadian Armed Forces funded RWE-CAF Research Network.

Did your colleagues develop an inspiring educational innovation? Or, did you collaborate with teachers and/or support staff to do so? You can nominate them for the Casimir Prize!

Some bacteria, it turns out, have proteins much like ours that organise the DNA in their cells. They just do it a bit differently. This is revealed by new research from biochemists at the Leiden Institute of Chemistry and the Max Planck Institute for Biology. The discovery helps us better understand…

A cancer pill, preferably without severe side effects, is something we’d all welcome. Is it a matter of time before such a pill is a reality? We put this question to three Leiden researchers and asked how they themselves are contributing to new cancer treatments.

Recently, Bram Slütter, Amanda Foks and Ilze Bot all individually obtained an ERA4Health research grant from the CARDINNOV 2023 program. In this program, which is co-funded by the EU and in the Netherlands by ZonMW, 17 consortia consisting of 3-5 European academic partners were selected for funding…

Leila Akkari was appointed Special Professor of Cancer-immune interactions at the Leiden Institute of Chemistry (LIC) on 15 December. Akkari is a researcher at the Netherlands Cancer Institute (NKI), where she studies the relationship between cancer cells and the immune system, with a particular focus…

On November 25th, BPS students Bart van Lieshout (right) and Scott Engels (left) received Dr. Saal van Zwanenberg Research Prizes from the KHMW. This annual prize is awarded to students who have written a master's thesis in the pharmaceutical and medical sciences field.

The transcription factor MYC is a master regulator implicated in the majority of human cancers. Despite its central role, MYC has long been considered "undruggable" by small molecules, lacking binding pockets and featuring disordered regions. While larger biomolecules could potentially disrupt MYC function,…

Human cells are protecting their proteins from unfolding and aggregating. That's what biophysicist Alireza Mashaghi and his team discovered after seven years of in-depth research into the folding mechanisms of proteins. With an unprecedented approach, the team was able to study the folding of a single…

A breakthrough from the PhD research of medical chemist Elmer Maurits may help patients with autoimmune diseases and blood cancer in the future. But bringing a discovery from the lab to the clinic is not so easily done. Thanks to NWO's Venture Challenge, Maurits and his team will receive ten weeks of…

Better supervision of PhD candidates, clear guidelines on career paths and an MRI scanner that can be accessed by all researchers: these are the recommendations from the new self-evaluation. Colleagues say: ‘This forces us as an institute to formulate our mission and vision more precisely.’

When internist Christian Blank made his very first discovery, his field of immunotherapy was the underdog of cancer research. Now, over 20 years later, Blank has been appointed Professor By Special Appointment of Internal Medicine for his clinical research into immunotherapy and will give his inaugural…

Donororganen zijn er nooit genoeg. De organen die wel beschikbaar zijn, moeten vliegensvlug getransplanteerd worden. De geneeskunde zet daarom volop in op het langer goedhouden van organen. Marlon de Haan (24) onderzoekt hoe je nieren buiten het lichaam in leven kunt houden.

A flu virus could cause a pandemic. And then we would be poorly armed because flu viruses are starting to become resistant to flu medications like Tamiflu. Chemist Merijn Vriends successfully worked on an improved version of such medications. He will be awarded his doctorate on September 12th.

One discovered that arteriosclerosis resembles an autoimmune disease, while the other developed a system to aid in the search for new medications. For these achievements, Marie Depuydt and Jurren de Groot were awarded the Krijn Rietveld Memorial Innovation Award on the evening of Tuesday 4 June.

3 October University has become something of a tradition: a bit of science among the Leidens Ontzet celebrations. During the new and improved edition, the WetenschapsWarenMarkt (Science Market), visitors spoke to researchers about the nitrogen problem, making organs and the city’s connections with A…

It was a memorable start to September. While Leiden marked the opening of the academic year, The Hague celebrated the launch of three new degree programmes. Students were welcomed on a blue carpet rolled out at the entrance to the lecture halls.

Smart drug carriers, uneven cosmic expansion, and solar energy storage in molecules. These are the topics of three newly awarded NWO-XS grants to researchers at the Faculty of Science.

As a bachelor student of Bio-Pharmaceutical Sciences, Femke Vlaswinkel wrote a research proposal she was allowed to carry out in her master’s BPS. Femke subsequently graduated with honors. Her research was published in the journal Scientific Reports, she won an award from the Dutch Pharmacy Society…

This summer, one of our BPS-master students, Ramazan Kiliç, will travel to Baltimore to present his research at the annual ARRE Research Symposium, a conference on ASXL-disorders that attracts researchers from all over the world, including the US, Japan, Germany, Ireland and, of course, The Netherlands.…

Tracking mucus-eating bacteria, mapping the complexity of planetary nebulae and a signalling pathway in cancer. These three Leiden projects have been awarded Open Competition Science-M funding by the Dutch Research Council.

The fact that scientists are increasingly better able to access molecular cell and tissue data also brings with it a new challenge: how can scientists find the information they need for research among the vast amount of data available?

Yeast, alpacas, and antibodies. They may seem unrelated, but within the project of the Leiden iGEM students, they come together perfectly. For the international synthetic biology competition iGEM, the team is working on an innovative method to produce nanobodies—a special form of antibodies—using brewer’s…

A team of LACDR scientists from three different divisions (SPP, BT, MC) contributed to a book on "Substance P in Health and Disease," which will be published by Elsevier. The project was a collaboration with Hannover Medical School (Germany) and was coordinated by Alireza Mashaghi. Master students Ehsan…

Eleven researchers from Leiden University have been awarded an Open Competition Domain Science ENW XS grant by the Dutch Research Council for their research projects. They are researching how to make software faster and greener, improve cancer detection and reduce anxiety by manipulating the biological…

An impressive 22 research projects by Leiden researchers have been awarded Veni funding from the Dutch Research Council (NWO).

Leiden researchers have found clues to why a rare pregnancy disorder is mild in some babies but life-threatening in others. Their discovery opens the door to a test that could identify severe cases during pregnancy. Fortunately, a treatment already exists.

Collaboration is worthwhile. A joint LUMC and Leiden Law School project has received €142,500 from the Dutch Research Council (NWO). This grant will advance research into the law and ethics of regenerative medicine.

People with relatively high levels of lipids in their blood are less likely to develop allergic conditions such as eczema and asthma. These lipids cause genes that play a key role in allergic reactions to be less active. Researchers from the Leiden University Medical Center (LUMC) have published an…

Studying surfaces of solid materials: it may not seem relevant to energy consumption, but it is. Marcel Rost studies how platinum electrodes wear out. Those electrodes are a crucial component in the fuel cells of hydrogen-powered cars. ‘We need to make the switch from fossil fuel energy to hydrogen.…

Dying from viral infection due to organ failure and blood loss: we still know little about how it can happen. Among other things, Huaqi Tang developed an organ-on-a-chip to figure it out. 'These technologies can offer unprecedented opportunities to fight the viruses that threaten our society.' Tang…

Exceptional collaboration between physicians is needed to better understand and treat autoimmune diseases that cause inflammation in various organ systems.

Jonathan Powell came to Leiden from England to conduct research into the role of women in early modern court cases. In addition to all kinds of exciting documents, he also discovered the biscuits from the Water & Bloem bakery and the wild flowers at the Groenesteeg cemetery.