The LUMC Flow Cytometry Core Facility accommodates all research and diagnostic flow cytometry equipment of the LUMC.

Promotor: G.P. van Wezel, Co-promotor: D. Claessen

An overview of our infrastructure at the SPP division:

Worldwide resurgence of pertussis necessitates the need for improvement of pertussis vaccines and vaccination strategies.

This is a facility where research groups or small companies can apply for space if they need to culture human or animal cells.

In this thesis, single-cell approaches were applied to characterize the impact of aging on the immunological B cell landscape in different models of atherosclerotic cardiovascular disease, with the goal to identify and study new B cell-associated biomarkers and therapeutic targets to halt atherosclerosis…

Leiden researchers have found clues to why a rare pregnancy disorder is mild in some babies but life-threatening in others. Their discovery opens the door to a test that could identify severe cases during pregnancy. Fortunately, a treatment already exists.

Key publications of the Cardiovascular Pharmacology group

We aim to engineer streptomycetes to fully exploit their potential for natural product productions, by a rational design and evolution approach.

In brain diseases such as Parkinson's and Alzheimer's, proteins clump together to form fibres. ‘Chaperone proteins’ unravel those fibres, but in the test tube biochemist Anne Wentink saw that this can also cause new problems. She is going to find out what happens inside cells to determine what a drug…

Despite considerable progress in the design of multifunctionalized nanoparticles (NPs) that selectively target specific cell types, their systemic application often results in unwanted liver accumulation. The exact mechanisms for this general observation are still unclear.

Osteoarchaeologists help forensic scientists solve crimes. They also study bone material from the Second World War in order to identify victims.

Leiden archaeologists investigate how people in the past impacted their environment. Together with scientists, environmental scientists, and humanities experts, they use this information to draw conclusions about the present – and show what we can learn from it for the future.

Promotores: S.F. Portegies Zwart, E. M. Rossi

Are you a British citizen currently studying at Leiden University? Find out about the effects of Brexit such as the transition period, residence permits, tuition fees and more.

Archaic and Classical architectural terracottas constituted an integral part of the architecture of monumental buildings at Akragas. These objects therefore provide unique insights into the built environment of sanctuaries at this important Greek colony in Sicily. This research's multi-disciplinary…

Morphometric and morphological differences have been used extensively in the past to study domestication of the wolf and the origin of dogs. Certainly before genetic testing was performed, these methods were the only means to diverge both groups. But still now, when aDNA cannot be extracted, morphometry…

Like any language, the natural sign languages of deaf communities differ from each other in their grammars and lexicons. A growing number of studies indicates that sign languages make use of the gestures of hearing speakers to build linguistic structure. This implies that variation and similarities…

Coming to and living in The Netherlands after Brexit.

Maria Yazdanbakhsh, Professor of Parasitology at the Leiden University Medical Centre (LUMC), has been awarded an ERC Advanced Grant of 2.5 million euros. She will investigate why people in Africa and Southeast Asia respond less to certain vaccines than Europeans. Her goal is to find a solution for…

Learning from small data sets in machine learning is a crucial challenge, especially when dealing with data imbalances and anomaly detection. This thesis delves into the challenges and methodologies of learning from small datasets in machine learning, with a particular focus on addressing data imbalances…

Like any language, the natural sign languages (henceforth: SLs) of deaf communities differ from each other in their grammars and lexicons. A growing number of studies indicates that SLs make use of the gestures of hearing speakers to build linguistic structure. This implies that variation and similarities…

Promotor: M. de Jong, Co-Promotor: Samtleben

Alzheimer’s disease and cancer are two examples of diseases that are related to malfunctioning cellular patterns. The examination of cell tissue, however, takes a lot of time and generates a lot of data. To make the analysis of data easier, Antonios Somarakis of the Data Science Research Programme (DSRP)…

Leiden researcher Dr Ben Zonneveld has determined the size of the genome - the amount of DNA per nucleus - of wild tulips. His conclusion is that there are more than 87 wild species. Various possibly new species have been discovered.

Researchers Indu Khatri, Frank Staal and Jacques van Dongen from Leiden University Medical Center (LUMC) have published a perspective article in Frontiers in Immunology about coronavirus and its characteristic ‘spike protein.’ They predict which antibodies would provide the best protection against the…

Social science research helps us understand human behaviour and social structures. These are determined by various factors, which makes the research complex and increases the likelihood of drawing the wrong conclusions. The choice of research method and analysis is therefore extremely important. It…

Smart algorithms and powerful processors are just as essential for astronomy as big telescopes. Astronomers at Leiden University therefore constantly operate at the interface between astronomy and data science.

Organized by the Grotius Centre for International Legal Studies, this programme enables students and professionals from all over the world to engage in discussions on the prospects and challenges of international criminal justice.

One of the current research projects funded by the profile area Political Legitimacy is the research group From Disorder to Order: Conflict and the Resources of Legitimacy.

Isotopic insights on human diet from the later stone age to Neolithic in Northwest Africa, Morocco

Biological cells, the basic building blocks of all life forms, are surrounded by a lipid membrane. More than half of the membrane is occupied by membrane proteins, which can regulate the cell functionality through specific arrangements.

The Mycenaean civilization of ancient Greek times offers enormous potential for useful information: from innovative construction methods to ways of handling crisis situations as a society. Archaeologist Ann Brysbaert and her team analyse Mycenaean construction processes in the ERC Consolidator project…

During this course, specialists from Leiden University and beyond will provide instruction on issues of editing, paleography and conservation of oriental manuscripts. They will also speak about philology, literacy and orality and the transmission of knowledge in the Islamic manuscript culture, presenting…

Leiden University archaeologists are reconstructing houses from the Stone Age, using only resources available during that period. This method offers surprising insights into the ingenuity of our distant ancestors, and challenges existing archaeological views.

New Approaches to the Study of Textual Material from the Early Pharaonic to the Late Antique Period