2,862 search results for “disease prevention” in the Public website
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Molecular Physiology
Molecular Physiology is a research group at the Leiden Institute of Chemistry dedicated to the design, synthesis and application of chemical tools to study important biological and biomedical questions. The group is headed by Prof. Dr. Mario van der Stelt and includes the research lines of Assistant…
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In vivo tracking and biodistribution of protein aggregates
Therapeutic proteins have revolutionized the treatment of many severe diseases like multiple sclerosis, haemophilia, diabetes and many more. Unfortunately, even recombinant proteins with structures (almost) identical to those of their endogenous counterparts often induce the formation of anti drug antibodies…
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Cell Observatory: visualising structures of life
From molecule, to cell, to organism. The high-level drug research at the Cell Observatory aimes at reducing the spread of cancer and developing new medicines for tuberculosis.
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Determining the kinetic profile of ENT1 inhibitors
Supervisor: Anna Vlachodimou
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COMMUNITY: unraveling the regulatory networks in Streptomyces that switch on antibiotic production on demand
Through his project we will unravel the global regulatory networks that control gene expression in Streptomyces bacteria and allow them to properly respond to major changes in the environment; we will then harness this knowledge to activate and identify novel antibiotics
- Lecture: Designing Modulators of Purinergic Signaling for Chronic Disease Treatment
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Rijksmuseum Boerhaave opens exhibition with major role for corona crisis
The ‘Contagious!’ exhibition was set to open at Rijksmuseum Boerhaave in April but had to be postponed because of the corona crisis. The museum hasn’t been twiddling its thumbs in the meantime. The exhibition will now open on 16 July, and the corona crisis has a major role.
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No higher risk of miscarriage after COVID-19
LUMC research has shown that women who previously had a miscarriage due to COVID-19 are not at increased risk of having another miscarriage or a stillbirth. Nor are preventive drugs needed during the pregnancy.
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Leiden biology appreciated with large NWO grants
A Vici grant and a Science-GROOT: scientists from the Institute of Biology Leiden have been awarded prestigious grants from the Dutch Research Council (NWO). From investigating bacteria without cell walls to harnessing plants with the help of microorganisms.
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Researchers tackle antibiotic-resistant bacteria
When a bacterium becomes more resistant to one antibiotic, it sometimes becomes more sensitive to another. To better understand this interaction, researchers from the Leiden Institute of Biology (IBL) and the Leiden Academic Center for Drug Research (LACDR) under supervision of Daniel Rozen and Coen…
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Rob van Wijk
Science
r.c.van.wijk@lacdr.leidenuniv.nl | +31 71 527 4505
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‘Like Don Quichot, you have to keep dreaming’
Having a bachelor, master and Ph.D in chemistry, Elena Sánchez López shifted to a more biological research for her postdoc. All of her studies she did at the University of Alcala, in Spain. Way back in medieval times, this city was the place of birth of Miguel de Cervantes, author of the world famous…
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Tumours can use ‘remote control’ to attract blood vessels
Researchers at Leiden University have demonstrated that tumours can apply mechanical means to attract the blood vessels they need to be able to grow. The team published this discovery on 2 March in Nature Scientific Reports.
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Unsafe products in e-commerce
European product safety law is one of the focal points of internal market legislation.
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Tackling chronic respiratory disease in low-resource settings
PhD defence
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Halting protein degradation may contribute to new cancer treatment
Chemist Gerjan de Bruin has designed a method of slowing down the degradation process of proteins in cells. This may contribute to new cancer medicines with fewer side-effects. PhD defence on 1 June.
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Women and Peacebuilding: A Multilevel Perspective
Where are the Women in Global Governance and in peace processes?
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From bed to bench and back to the future
Retrospection over the last 40 years the most important changes in care and research, where transparency accountability and guidelines became leading. On Huntington’s disease and cerebrovascular disorders the most important changes are illustrated.
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Replacing the needle and syringe for vaccine administration
Promotores: Prof.dr. G.F.A Kersten, Prof dr. J.A. Bouwstra
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John van Noort Lab - Chromatin Dynamics
Chromatin is an ubiquitous protein-DNA complex that forms the structural basis of DNA condensation in all eukaryotic organisms.
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System-level design for efficient execution of CNNs at the edge
A convolutional neural network (CNN) is a biologically inspired algorithm, highly capable at processing images and videos.
- Research
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Force sensing and transmission in human induced pluripotent stem-cell-derived pericytes
Pericytes, the mural cells of blood microvessels, are important regulators of vascular morphogenesis and function that have been postulated to mechanically control microvascular diameter through as yet unknown mechanisms.
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Topological decoding of biomolecular fold complexity
Biological polymers, including proteins and the genome, undergo folding processes crucial for their proper functioning. Even slight changes in the folding structure of these biopolymers can have significant implications, leading to the development of various pathological conditions, such as neurodegenerative…
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Topic: Work and health
The research connected to this topic is related to Work and health.
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Core cross-linked polymeric micelles based on polypept(o)ides: from secondary structure formation of polypeptides to functional cross-linking
This thesis aimed to investigate core cross-linked polymeric micelles (CCPMs) and expand their potential for the delivery of hydrophobic drugs and co-factors.
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Martin Giera
Assistant Professor at the Metabolomics group, LUMC, The Nederlands
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Louise Jawerth Lab
Research in the Jawerth lab focuses on using principles from soft condensed matter physics to understand important biological materials.
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Natural and non-natural factors influencing Alzheimer´s Aβ
Promotor: Prof.dr. J.P. Abrahams
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The diverse roles of integrin α3β1 in cancer: Lessons learned from skin and breast carcinogenesis
In this thesis, we aim to shed light on the diverse and often opposing roles of integrin α3β1 in cancer.
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A novel biofilm for skin barrier repair of patients with atopic eczema
Atopic eczema is a skin disease with increasing incidence currently affecting 25% of the paediatric population. In atopic eczema the skin barrier function is reduced. This barrier is formed by the outermost layer of the skin called the stratum corneum (SC). The SC consists of terminally differentiated…
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Novel receptor concepts
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Biotherapeutic Delivery
The research of the Biotherapeutic Delivery group led by Joachim Van Guyse focuses on developing novel polymer-based formulations for therapeutic nucleic acid and protein delivery. The research revolves around developing structure-activity relationships between the chemical structure of polymers, the…
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The LeiCNS-PK3.0 model development and applications: healthy-to-diseased CNS pharmacokinetic translation
Accurate prediction of the unbound drug concentration-time profile at the CNS target site is crucial for the assessment of the right drug concentration-effect relationship. PBPK models have supported the PK prediction of the CNS target sites and the translation of PK data between species and between…
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Strategy
The research area of this division is focused on the development of novel therapeutic modalities and novel concepts in early drug discovery, in order to better predict ligand-target interactions.
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Healthy ageing
The elderly accept may minor discomforts like stiffer muscles and getting tired more quickly, but they do want to go to their children's birthdays independently. Preventive elderly care helps people with that. The goal is to let people grow old while maintaining their self-reliance and independence…
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Bio-organic Synthesis
The research in the Biosyn group is focused on the design, synthesis and function of the four major types of biomolecules: nucleic acids, carbohydrates, peptides and lipids and hybrid structures thereof. These biomolecules and their derivatives are used in drug discovery and chemical biology, to develop…
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Stress-related prolonged cardiovascular activity: The impact and changeability of stressful cognition without awareness
The research question is that unconscious perseverative cognition (UPC) is responsible for a considerable part of cardiovascular (CV) activity that occurs even in the absence of threats and other stressors that one may encounter in one’s daily life.
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Minors
The minors offered by the Faculty of Governance and Global Affairs in The Hague are closely linked to the defining image of The Hague as a city of international justice, peace and security as well as the centre of Dutch public administration and international governance.
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Train your brain!
Neuroimaging research has greatly advanced our insights on how the brain is organized. Now is the time for the next step: Imagine what would be possible when we cannot only map brain-functioning, but use neuroimaging to voluntarily regulate brain-activity!
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From scientific idea to promising new drug
Many pharmaceutical companies no longer have their own lab and are working more closely with universities and start-ups of scientists. Professor of Science-Based Business Simcha Jong is researching how scientific ideas result in new drugs, including at the Leiden Bio Science Park (LBSP).
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How a Leiden professor came to be a Waterloo hero
With his knowledge of medicine and his decisive action, Leiden professor Sebald Justinus Brugmans saved the lives of many wounded soldiers after the Battle of Waterloo, on 18 June 2015 exactly 200 years ago.
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Subsidie voor Shelley van der Veek om peuters gezonde eetgewoonten aan te leren
Het onderzoeksproject heeft als doel ouders te helpen hun kleuters gezonde eetgewoonten aan te leren door het bevorderen van sensitieve voeding tijdens de fase wanneer peuters kieskeurig met eten worden.
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In shape for photoregulation
How does the photoregulation mechanism work in detail?
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SPRING
In this project we followed children of parents with an anxiety disorder. We wanted to examine how these children develop and try to better understand why it is that some children develop fears, whilst other children do not. In this project, we mainly focus on social anxiety disorder and panic disor…
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Born to be shy?
An international mega-analysis on the neurobiological link between inhibited temperament and social anxiety disorder
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Conflict, Conflict Resolution and Crisis Management
This research cluster is a part of the Institute of Political Science’s research programme ‘Institutions, Decisions and Collective Behaviour’. Its members investigate the drivers of political conflict and various types of crises. They study how citizens, political institutions and international organizations…
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Economic value of non-timber forest products among Paser Indigenous People of East Kalimantan
Promotor: G.A. Persoon, Co-promotor: H.H. de Iongh
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PhD psychologist
A substantial part of PhD candidates have an increased risk for mental health problems, stress complaints or burnout. Leiden University has appointed a psychologist, especially for PhD candidates: Agnes van Rossum.
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Career prospects
A master's degree in Psychology at Leiden University combines theoretical knowledge with academic and professional skills, making you an attractive candidate for many employers.