426 search results for “bacteria” in the Public website
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3D printed microboat
From prow to stern, this little boat measures 30 micrometers, about a third of the thickness of a hair. It has been 3D-printed by Leiden physicists Rachel Doherty, Daniela Kraft and colleagues.
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Cancer pathogenesis and therapy
With cancer, a person’s body cells grow uncontrollably. Putting together a detailed picture of how this comes about makes it possible to develop efficient therapies. Researchers at the Leiden University Medical Centre (LUMC) and Leiden University are working together to gain a better understanding…
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Publications
Relevant publications of the CIGR participants.
- Lectures
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NWO grant gives way to more sustainable production of antibiotics
The opportunity to explore a new, exciting research topic. That is how Lennart Schada von Borzyskowski describes his successful application for the NWO XS grant. It comprises 50,000 euros, which the researcher from the Institute of Biology Leiden (IBL) will spend on investigating a more sustainable…
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Leiden biologist receives National Zoology Award
Maurijn van der Zee, evolutionary biologist at the IBL, received the National Zoology Award for his research on the evolutionary success of the insects. The award was handed out last Saturday, the 17th of December, by Professor Jan Kammenga, chairman of the Royal Dutch Zoological society.
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Amanda Foks receives prestigious Junior Postdoc fellowship
Dr. Amanda Foks obtained a fellowship from the dr. E. Dekker-program for the project ' Can promotion of efferocytosis induce regression of atherosclerosis?', in which she aims to identify novel targets to promote regression of atherosclerosis. This research grant allows her to initiate independent research…
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Macrophages as drivers of an opportunistic infection
The opportunistic bacterium Burkholderia cenocepacia is feared by cystic fibrosis patients and is emerging in hospital-acquired infections. An international study sheds new light on the infection mechanism of this opportunistic pathogen that may have large implications for treatment strategies.
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“Principles of Plant-Microbe Interactions”
Emeritus Professor Ben Lugtenberg edited a book on “Principles of Plant-Microbe Interactions” together with Paul Hooykaas, Eddy van der Meijden and Jos Raaijmakers, all from the IBL.
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Proteins and DNA loops: Science-Groot grant for Remus Dame
How do our cells keep DNA stored away? To find out, biochemist Remus Dame received a 3 million euro Science-Groot grant. Leiden University will share the grant with TU Delft, VU Amsterdam and the Hubrecht Institute.
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What Darwin couldn’t see: Expedition to uncover invisible life in Galápagos
An international research team is to search for invisible life in the Galápagos Islands. The diversity of bacteria and other microscopic organisms may not be evident to the naked eye, but it is essential to nature. To the islands' giant daisies, for instance: unique endemic plants that are currently…
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PhD candidates deserve special attention: their new confidential counsellor Annemarie Meijer explains why
She studied biology in Leiden and never left. Now, as Professor of Immunobiology, Annemarie Meijer has taken on the role of the new confidential counsell for for PhD candidates. It's a role that suits her perfectly: she has extensive experience in the research world and has guided dozens of PhD candidates.…
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Veni grants for 16 Leiden researchers
Sixteen researchers at Leiden University are to receive a Veni grant from the Netherlands Organisation for Scientific Research (NWO). These awards offer promising young researchers the opportunity to further develop their own ideas over a period of three years.
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Using gold particles to make the invisible visible
Gold nanoparticles give us a better understanding of enzymes and other molecules. Biswajit Pradhan, PhD candidate at the Leiden Institute of Physics, uses gold nanorods to study individual molecules that would be challenging to detect otherwise. Resulting knowledge can be applied to many research fields,…
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How oak seedlings teach us more on dune restoration
What is the best way to restore dune ecosystems? The project TERRA-Dunes researches the role of soil microbes in the development of natural dune areas. Recently, the project went into a new phase: planting 412 oak seedlings grown in different type of soils.
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Photosynthesis works with valves
Photosynthesis is the origin of life on earth, but it is a phenomenon that is still barely understood. Take, for example, the extremely efficient mechanism of electron transport. Leiden researchers demonstrate for the first time where one particular cause of this might be found.
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Steering the immune system with liposomes
Liposomes – nano-sized spheres composed of fatty molecules – are very promising for vaccination. Bio-pharmaceutical scientist Naomi Benne discovered that the immune response in animal models can be steered by varying the charge of the liposomes. She obtained her PhD degree on 8 September for this research,…
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Paco Barona Gomez ready to work in Leiden: ‘Fundamental research creates opportunities’
Paco Barona Gomez is the newest associate professor at the Institute of Biology Leiden (IBL). The Mexican researcher is fascinated by the evolution of natural products: compounds made by microbes, but also plants and animals. ‘It’s like we investigate chemical dark matter.’
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Aphid genome unravelled
Leiden evolutionary biologist Maurijn van der Zee has co-operated on an enormous international project to describe the genetic material of the pea aphid Acyrthosiphon pisum. The more than 100 authors involved in the project have published their findings in the online magazine PLoS Biology.
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Using tweezers of light to study the misfolding proteins of muscular diseases
Alireza Mashaghi from the Leiden Academic Centre for Drug Research (LACDR) will use state-of-the-art technology to investigate proteins that play a role in muscular dystrophy. His goal is to provide new insights for designing novel therapeutic strategies in the future. To accomplish this, Mashaghi receives…
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Looking at the big world of microbiology through the smallest lenses
Antoni van Leeuwenhoek, the father of microbiology, died 300 years ago. 2023 has therefore been designated the Antoni van Leeuwenhoek year. The new Unimaginable exhibition in Rijksmuseum Boerhaave is about the amazing world that Van Leeuwenhoek made visible. What was so special about the way he worked?…
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Thierry Rohmer received Ernst Award for elucidating the light-switch of plants
PhD student Thierry Rohmer received the Ernst Award 2009 of the Gesellschaft Deutscher Chemiker (GDCh) for his publication in the Proceedings of the National Academy of Science of the USA on the structure-function relation of the photoreceptor phytochrome. The prize was presented at the Annual Discussion…
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Fifty Shades of Stress
The challenge: Building a tool to detect chemical compounds that individually cause non-lethal stress to bacteria, but that are lethal in combination. A team of thirteen Leiden students are taking up this challenge in the annual ‘international Genetically Engineered Machine’ (iGEM) competition for applications…
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Using AI to Combat Drug Resistance - an Interview with PhD student Rosan Kuin
Rosan Kuin started her PhD in July at the LACDR under supervision of prof. Gerard van Westen and Dr. Meindert Lamers. She completed a BSc. in Pharmaceutical Sciences at the VU University in Amsterdam in 2017. After that she started two master programs, Drug Discovery & Safety with a specialization in…
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Opening PoreLab
PoreLab is officially opened on November 1st, 2016. This new lab located at the Sylvius Laboratory will be working with the latest DNA analysis technology and will bring science, education and industry together to explore practical applications with the MinION.
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King opens new wing of Leiden Instrumentmakers School
King Willem-Alexander visited Leiden on 6 December to open the new wing of the Leiden Instrumentmakers School. Students of this vocational programme make instruments needed for scientific research.
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European collaboration shines a light on enzyme discovery for industry
A European consortium has provided a disruptive technological breakthrough to allow the discovery and characterization of novel enzymes for industrial biotechnology. The technology will open the way to more efficient industrial processes such as in the biofuel, animal feed and paper and pulp industr…
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Zebrafish models for disease and environmental stress
We use zebrafish as a model organism to study human development and disease as well as animal welfare and environmental impact.
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Wat is er te doen op de Leidse Museumnacht?
Op zaterdag 3 juni vindt de Museumnacht Leiden plaats. Ook dit jaar zijn Leidse wetenschappers en studenten onderdeel van de programmering.
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New research into hidden nature in our cities
What hidden nature is there in our cities and how can we use such organisms? This is what the HiddenBiodiversity project will be exploring over the next four years. The project’s kick-off meeting was held at the Hortus botanicus on Monday 26 September.
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New IBL-professor in Ultrastructural Biology: Ariane Briegel
Ariane Briegel has been appointed Professor in the fìeld of Ultrastructural Biology within the Faculty of Science at the Institute of Biology from the 1st of December 2015. Her expertise is in using electron cryotomography to study how microbes sense and respond to their environment.
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Living Labs and ‘pavement plants’: Leiden University’s contributions to biodiversity
Through various initiatives, Leiden University is trying to make people aware of the importance of biodiversity: the cultivation of a wide variety of micro-organisms, animals and plant species. This is important because in the Netherlands biodiversity has declined from about 40 percent in 1900 to about…
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Ilze Bot receives prestigious grant from the Dutch Heart Foundation
Just before Christmas, three talented scientists received good news: they are receiving a personal research grant from the Dutch Heart Foundation. Ilze Bot of the Leiden Academic Centre for Drug Research is one of those scientists. She will receive an Established Investigator grant of 650,000 euros.…
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Record distance for alternative super current
Electrons that spin synchronously around their axis, turn out to stay superconducting across large distances within magnetic chromium dioxide. Electric current from these electrons can flip small magnets, and its superconducting version could form the basis for a hard drive without energy loss. Publication…
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Two new publications by Sven Lütticken
In September Lütticken released two new publications: 'Objections- Forms of Abstraction, Volume 1' and 'Art and Autonomy: A Critical Reader'.
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'A garden on Mars' crowdfunding campaign starts today
Today, 13 students at Leiden University have started a crowdfunding campaign to collect money for research into the possibilities of growing crops on Mars. Their research will contribute to the knowledge of our galaxy. The project is in the context of the iGEM competition.
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New Scientific Director for the Institute of Biology Leiden
Gilles van Wezel has been appointed the new Scientific Director of the Institute of Biology Leiden starting September 1st, 2018. Van Wezel succeeds Herman Spaink, who has been the Scientific Director since September 2014.
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What if superbugs were as tall as buildings?
In Sci-Fi comic book Resist NOW!, wondrous adventures will illustrate possibilities to combat antimicrobial resistance. But the comic book will only be produced if enough money is raised to make the project into reality.
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Smart design carries sound one way
A new computer simulation shows the promising possibilities of the booming field of topology. Smartly designed mechanical structures carry sound exclusively one way and are immune to fabrication errors. Publication on 17 July in Nature Physics.
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PhD Theses
A full overview of BPOC/SSNMR PhD theses.
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Leiden University Medical Center
In the Leiden University Medical Centre (LUMC) we strive to improve health care and the health of people.
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Activity-based protein profiling for drug discovery
Activity-based protein profiling (ABPP, also termed chemical proteomics), is one of the pillars of chemical biology, and at LED3 we have taken it to the next level. ABPP allows the assessment of protein function in live cells and tissues, which means that the activity of a complete protein family can…
- Interdisciplinary Activity Grants
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Plant Scientist for a day
Small workshop
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The quest for more antibiotics
Streptomycetes are similar to moulds, but these bacteria live in the soil. They are very popular in biotechnology because they produce a great many antibiotics and enzymes. Gilles van Wezel will be using his Vici subsidy to study ways of increasing their production.
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Regulation of autophagy-related mechanisms during bacterial infection
PhD defence
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'Soil is the basis of our lives' - Martijn Bezemer nominated for Huibregtsen Prize 2023
Directing soil life and thereby influencing what grows above ground: that is the expertise of Leiden biologist Martijn Bezemer and his colleague Wim van der Putten (NIOO-KNAW). Their research on soil transplants has been nominated for the Huibregtsen Prize 2023. This prize goes to innovative research…
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Students make podcasts about micro- and bioplastics
Four Master's students Science Communication & Society made two podcasts on the theme Plastic for the end project of their study programme. With the podcasts, they helped the Institute of Biology Leiden (IBL) to draw attention to plastic pollution. And that was harder than it seemed. 'Be sure to test…
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Briegel winner in global competition by the Moore Foundation
Ariane Briegel, Professor of Ultrastructural biology in Leiden, has received a prestigious incentive from the Gordon and Betty Moore Foundation. With the grant of 800,000 euros, Briegel will set up a new research line into studying symbiotic interactions on the nanoscale.
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New light on innate plant immunity
Plants are able to resist a pathogen’s attack by a dual innate immune system. The relationship between the two pathways was not clear, but it turns out that they mutually potentiate each other, as assistant professor Pingtao Ding (Institute of Biology Leiden) and colleagues (The Sainsbury Laboratory,…