369 search results for “t cells” in the Staff website
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Don't be fooled by phishing
You think you can spot a phishing scam: a suspicious email that asks for your password or other personal data. But these emails are becoming increasingly plausible, so you could still fall into the trap. That’s why this method is still used so often by people with malicious intent. Did you know that…
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Marjolein Crooijmans
Science
m.e.crooijmans@biology.leidenuniv.nl | +31 71 527 5075
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How cells talk by pulling on a fibre network
Mechanics play a larger role in blood vessel formation, and other developmental biology, than previously thought. Cells appear to respond to mechanical signals, such as pressure. Through the extracellular matrix, a network of fibrous proteins, cells can supposedly exchange those mechanical signals over…
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forming embryo to cancer metastasis: the significance of collective cell movement
Luca Giomi has the first results of his ERC consolidator grant. He discovered that epithelial cells move collectively but in different ways, depending on the scale you look at. It is hexatic at small scales, and becomes nematic at larger scales: it is a multiscale order. This collective movement of…
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Bacteria without cell wall gobble up DNA from environment
A bacterium hiding from the immune system and picking up bits of DNA from its environment. The result: gaining new traits, such as better protection against antibiotics. Fortunately, we have not found such a damning scenario yet. However, PhD student Renée Kapteijn did find the first clues, which…
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Saloni Saxena
Science
s.saxena@biology.leidenuniv.nl | +31 71 527 4950
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First patient in the Netherlands successfully treated with stem cell gene therapy
Researchers from the Leiden University Medical Center (LUMC) have successfully used stem cell gene therapy to treat a baby with the severe congenital immune disorder SCID. An important milestone: it is the first time stem cell gene therapy of Dutch origin has been administered to a patient, and also…
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Stiffness and viscosity of cells differ in cancer and other diseases
During illness, the stiffness or viscosity of cells can change. Tom Evers demonstrated this by measuring such properties of human immune cells for the first time. ‘The stiffness of certain cells could be a way to make a diagnosis,’ Evers said. He defended his thesis on March 26th.
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Sander van Kasteren: from molecule builder to Professor of Chemical Immunology
Sander van Kasteren only noticed some small, subtle changes since he was appointed professor on 1 May. Still, he has to get used to the idea, even though he had been working towards the professorship for a few years. ‘I don't quite see myself as a professor yet.'
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Inexhaustible source of human heart muscle cells allows strong reduction of animal testing
Researchers at the Leiden University Medical Centre (LUMC) have managed to culture human heart muscle cells on a massive scale. This is an exceptional achievement because it is very difficult to replicate heart muscle cells outside the body. Using a special technique, the researchers have now created…
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LUMC will administer first Dutch stem cell gene therapy to patients
Researchers and clinicians at Leiden University Medical Centre (LUMC) are about to begin a milestone clinical study. It will be the first time a stem cell gene therapy developed in the Netherlands is used in a clinic. The therapy will be used to treat children with SCID, a rare disorder where children…
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A unique defence: Bacteria lose cell wall in the presence of virus
Bacteria temporarily live without their cell wall if dangerous viruses are near. A remarkable feature, as the cell wall is a sturdy barrier against threats. Still, the discovery has a logical explanation ánd might be of a consequence for fighting pathogenic bacteria, according to Véronique Ongenae,…
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How cells determine the fate of proteins (and can we do it too?)
Cells in our bodies are often threatened by errors in our own proteins. The FLOW consortium, comprising scientists from various institutions including Leiden, is poised to meticulously map out for the first time how cells control proteins, correcting or removing faulty ones. This endeavour holds promise…
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Caught in living cells: how bacteria regulate their genes to defend themselves
For the first time, it was shown in living cells how the bacterium E. coli regulates genes that help it survive in a new environment. Biochemist Fatema Zahra Rashid managed to do this using a technique she fine-tuned. Her research into changes in 3-dimensional chromosome structure offers clues for ways…
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EIC Pathfinder Challenge grant for research into autoreactive B cells in cardiovascular disease
At the division of BioTherapeutics, Amanda Foks, Bram Slütter and Ilze Bot have obtained a €4 million research grant from the HORIZON 2022 EIC Pathfinder Challenge “Cardiogenomics”, entitled “B-specific: B-cell related gene and protein markers with prognostic and therapeutic value for CVD”.
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Serkan Aslan
Science
s.aslan@lacdr.leidenuniv.nl | +31 71 527 5919
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Tunnel vision alarm in the search for more efficient hydrogen cells
A tenacious postdoc researcher persuaded Professor Marc Koper to research the oxygen reduction reaction. In Koper's eyes, there was little of interest there. But they promptly discovered a whole new way to improve fuel cells on hydrogen and oxygen. Their article appeared in Nature Catalysis on 07 Ju…
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Physics in the picture: cancer cells as an explosion of fireworks
When you think of physics, do you think only of complicated formulas? You’re not the only one. Therefore, every year, the Leiden Insitute of Physics organises the LION Image Award to show another side of physics: beautiful images about intriguing science. The winner of the 2022 photo competition captured…
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Remko Offringa
Science
r.offringa@biology.leidenuniv.nl | +31 71 527 5097
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Joey Zuijdervelt
Science
j.l.zuijdervelt@lacdr.leidenuniv.nl | +31 71 527 6227
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Taarique teaches career planning but doesn’t want students to plan their future too strictly: ‘Keep on experimenting’
In the ‘Educatips’ column, psychology lecturers share their most important insights on teaching. This month: Taarique Debidin thinks making contact with one another is more important than cramming knowledge. ‘I’d get no energy at all from being a formal lecturer.’
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Innovating Cell Pharmacy with stem cells
Lecture
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Why arteriosclerosis looks like an autoimmune disease
Arteriosclerosis bears great similarities to autoimmune diseases. Researchers from Leiden University show this in a new study they published in the renowned scientific journal Nature Cardiovascular Research. 'This discovery suggests that treatment methods for autoimmune diseases might also be effective…
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Cell Pharmacy
Inaugural lecture
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WCN research prize for Marie Depuydt
During the 36th Scientific CardioVascular Congress, which was held last November in Amsterdam, Marie Depuydt from the BioTherapeutics division received the 2nd prize in the WCN research competition for her work (Vereniging Werkgroep Cardiologische centra Nederland (WCN)).
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Herman Spaink
Science
h.p.spaink@biology.leidenuniv.nl | +31 71 527 5055
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Bas ter Braak
Science
s.j.ter.braak@lacdr.leidenuniv.nl | +31 71 527 2727
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Interview Micha Drukker
Micha Drukker
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Forces and Symmetries in Cells and Tissues
PhD defence
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Unravelling cell fate decisions through single cell methods and mathematical models
PhD defence
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Curing diseases with lab-grown organs
Organs and tissues grown in the lab may in the future be able to cure people with organ failures. Micha Drukker, professor of Stem Cells, Developmental Biology and Technology for Innovative Drug Research, is convinced that the use of stem cells will make this possible. He will deliver his inaugural…
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Nature Communications paper on therapeutic melanoma inhibition by local micelle-mediated cyclic nucleotide repression
Cancer immunotherapy represents a significant breakthrough in cancer treatment. However, tumors have numerous mechanisms by which they evade destruction by the immune system. It is therefore necessary to decipher and reverse these mechanisms in order to improve immunotherapies.
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Mechanisms and consequences of horizontal gene transfer in cell wall- deficient cells of Kitasatospora viridifaciens
PhD defence
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Peter Bouwman
Science
r.j.p.bouwman@lacdr.leidenuniv.nl | +31 71 527 6105
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‘Don’t assess academic CVs on autopilot’
Hiring academics is more than just tallying up publications, says academic director and history professor Jeroen Duindam. He and his colleagues have come up with tips and guidelines for interview committees that align with the new system of recognition and rewards.
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New Master’s programme in Transfusion Medicine and Cellular and Tissue Therapies
LUMC and Leiden University will start the new two-year online master's program in Transfusion Medicine and Cellular and Tissue Therapies from October 2023.
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Applications of multisource data-based dynamic modeling to cell-cell signaling and infectious disease spreading
PhD defence
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Click to Release for Immunce Cell Activation
PhD defence
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Single-cell immune profiling of atherosclerosis
PhD defence
- Phone scams: don’t be a victim
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Single-cell mechanics for disease biology and pharmacology
PhD defence
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Why people confess to crimes they didn’t commit
When under duress innocent suspects can make a false confession. Why is this? Legal psychologist Linda Geven will give a talk about this at the Leiden Institute for Brain and Cognition’s Brain & Law event. At this symposium (in Dutch) on 16 September you can attend talks on fascinating brain research…
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Exhibition on scripts at Oude UB: Pseudo or Don’t
What is writing? And what looks like writing, but isn’t? The Pseudo or Don’t pop-up exhibition explores the boundaries of scripts. The exhibition will run at Oude UB from 9 to 26 October.
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‘The child protection system really isn’t in good order’
Last Thursday the Dutch House of Representatives held a debate on children being put into care when the childcare benefits scandal (toeslagenaffaire) had caused problems for their families. Four Leiden University academics were asked by the House to produce a fact sheet for this debate, bringing together…
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‘Technology shouldn’t shape our future; we should’
Technology holds so much promise – from self-driving cars to enhanced physical performance from smart implants under the skin. But we should not let ourselves be caught off guard. That is the message of Bart Custers, Professor of Law and Data Science in his inaugural lecture on 21 May. ‘We don’t talk…
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2023 Annual T.M.C. Asser lecture by Michael Fakhri
Research
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Privacy: don’t wait too long to seek help
ICT
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Diversity and inclusion: ‘Don’t avoid the subject'
The new online diversity and inclusion dossier combines all faculty initiatives on this topic. But what is the situation on diversity and inclusion at Humanities? An interview with Aurelie van ‘t Slot, policy advisor Internationalisation, Diversity and Inclusion.
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Technology alone won't save us from the climate crisis
If European countries rely solely on technological advances, they won't be able to limit global heating to 1.5 degrees. Households will also need to change their lifestyles. This 'inconvenient truth' is the result of calculations done by industrial ecologist Stephanie Cap. ‘It's not a popular message,…
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‘Immigration doesn’t threaten welfare states’
It is often thought that immigration threatens the solidarity on which redistribution relies. But looking at the post-war period, PhD candidate Emily Anne Wolff finds that this is not the case.