1,087 search results for “global gene regulation” in the Public website
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Honours students of the ‘Tackling Global Challenges’ track present their impact projects
On 8 December, Friday afternoon, the second year students of the Honours College track ‘Tackling Global Challenges’ presented their final assignment for the Competences Lab course. The goal was to set up an impact project and organize an event about it. The diverse groups listened and shared their ideas…
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Hans-Martien ten Napel writes article for LSE Religion and Global Society Blog
On 15 July 2019 Hans-Martien ten Napel started a new series on freedom of religion or belief for the London School of Economics research-led interdisciplinary Religion and Global Society Blog.
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Simon Willmetts in the Leiden Security and Global Affairs podcast about the CIA
Simon Willmetts walks listeners through the founding of the CIA, its successes, controversies, portrayal in media and film.
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Dr Vasiliki Kosta speaks at the Global Forum on Democratizing Work on 6 October 2021
Dr. Kosta presented at the Global Forum on Democratizing Work.
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Special annex dedicate to Faculty of Governance and Global Affairs in 'Den Haag Centraal'
On Thursday 8 September, the Hague newspaper 'Den Haag Centraal' issued a special annex dedicated to the Faculty of Governance and Global Affairs.
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Fraskou presents a paper at the International Conference "Europe as a Global Actor"
The Centro de Estudos Internacionais at Instituto Universitário de Lisboa (ISCTE-IUL) will host the
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Legal Empowerment of Pollution Victims in China and Indonesia
A political-legal study of rights invocation by pollution victims in China and Indonesia
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Briegel winner in global competition by the Moore Foundation
Ariane Briegel, Professor of Ultrastructural biology in Leiden, has received a prestigious incentive from the Gordon and Betty Moore Foundation. With the grant of 800,000 euros, Briegel will set up a new research line into studying symbiotic interactions on the nanoscale.
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User-friendly test brings global elimination of leprosy closer
Researchers from the Leiden University Medical Center (LUMC) are working on the first diagnostic test for leprosy that can be used outside a laboratory. This will not only reliably diagnose leprosy, but also be cheap and easy to use. Leprosy mainly occurs in low-income countries. A double challenge…
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Jan Kolen Director of LDE Center for Global Heritage and Development
Archaeologist Professor Jan Kolen has been appointed Director of the LDE Center for Global Heritage and Development (CGHD) with effect from 1 July 2013. This new inter-university heritage center is due to start in the autumn of 2013 within the framework of the strategic alliance between Leiden University,…
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Dutkiewicz, Casier & Scholte (eds.), Hegemony and World Order
Does hegemony—legitimated rule by dominant power—have a role in ordering world politics of the twenty-first century? If so, what form does that hegemony take: does it lie with a leading state or with some other force? How does contemporary world hegemony operate: what tools does it use and what outcomes…
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Moritz Jesse on BREXIT at Global Legal Network Conference in Tallinn
Moritz Jesse, Associate Professor of European Law at the Europa Institute, presented at the annual conference of the Global Legal Network, which took place in November in Tallin (Estonia).
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Summer School Writing global medieval history: comparative and connected approaches - September 6-8, Turin
Fondazione 1563 launched a call for the Summer School of the Turin Humanities Programme, that will take place in Torino from September 6 to September 8 2023. The theme is: Writing global medieval history: comparative and connected approaches. Deadline for applications: June 25.
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Four LUF Grants Awarded in 2020 to Faculty Governance and Global Affairs
The Leiden University Fund (LUF) awards grants to research and educational project in various academic fields once a year. This year, Andrei Poama, Jochem Jansen, Valérie Pattyn and Min Cho of the Faculty of Governance and Global Affairs were four of the recipients of such a grant.
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Participants
The CIGR comprises research groups from the Institute of Biology Leiden (IBL), the Leiden Institute of Chemistry (LIC), the Leiden Academic Centre for Drug Research (LACDR) and the Leiden Institue of Physics (LION).
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Innate immune defence against intracellular pathogens
What are the host immune defence mechanisms that control intracellular infections and how are these subverted by pathogens?
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Hit Discovery
The goal of hit discovery is to identify suitable chemical starting points to modulate a drug target. A hit can be, a.o., a small molecule, a protein or mRNA. Hit identification is performed via rational design, genome mining, (targeted) library screening, or in silico approaches.
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Cardiovascular and Metabolic Therapeutics
This research group, headed by Miranda van Eck, focusses on understanding the molecular mechanisms underlying cardiovascular and metabolic diseases. Cardiovascular disease constitutes a major health issue worldwide. Although significant knowledge has been obtained on the development of atherosclerotic…
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Stem cells as cure
Leiden has a long history in the treatment of blood cell cancer. Research to find better therapies never stands still. One of the potential treatments currently being worked on is a ‘living medicine’.
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Programme structure
The research master's specialisation Developmental Psychology consists of five main parts: the general courses, the specialisation-specific courses, the elective courses, a research internship and a thesis.
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New MOOC Security & Safety Challenges in a Globalized World, starting 23 January 2017.
Security and safety challenges are at the top of the list of the most pressing issues of contemporary society.
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Sound Practices in the Global South: Co-listening to Resounding Plurilogues
ACPA alumnus Budhaditya Chattopadhyay explores sound practices across South Asia, Africa, the Middle East, and Latin America in his new publication 'Sound Practices in the Global South: Co-listening to Resounding Plurilogues'.
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Beryl ter Haar "Special Issue: Covid-19 and Labour Law, A Global Review"
Beryl ter Haar co-editor of the Italian Labour Law e-Journal's
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Leiden Political Economy Group (L-PEG)
The Leiden Political Economy Group (L-PEG) is a multi-disciplinary network of scholars with a research interest in (comparative / global) political economy based at Leiden University. Our members belong to various institutes and faculties across Leiden University, and from other universities across…
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International Labour Organization: tumult on the global labour market
Since 1919 the International Labour Organization (ILO) has been promoting the rights of workers worldwide. On 7 February, Leiden University hosted the symposium celebrating the 100-year anniversary of the foundation of the ILO. Leiden emeritus professor of International Labour Law Paul van der Heijden…
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Francesco Ragazzi
Faculteit der Sociale Wetenschappen
f.ragazzi@fsw.leidenuniv.nl | +31 71 527 2727
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Maartje Janse
Faculty of Humanities
m.j.janse@hum.leidenuniv.nl | +31 71 527 4167
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Cells with stress: predicting drug-induced liver and kidney damage
How can we prevent drug-induced liver and kidney damage? PhD candidates Marije Niemeijer and Lukas Wijaya investigated what happens in the cells during the onset of this damage: a stress response. Both focused on a different subtopic and made some interesting discoveries.
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Dutch contribution to the development of African countries in the global value chain
Economies worldwide are increasingly interconnected; trade in raw materials and semi-finished products is increasing. Many products we use in the Netherlands originate abroad, and many products we make in the Netherlands are destined for other countries. Almost all countries around us participate in…
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Statistical methods for microarray data
Promotores: J.C. van Houwelingen, S.A. van de Geer
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Improving the filamentous fungus Aspergillus niger as cell factory for starch degrading enzymes
We aim to develop A. niger strains that produce more starch degrading enzymes even in the absence of starch.
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Institute of Biology Leiden
The Institute of Biology Leiden (IBL) is an internationally oriented institute for research and education in biology. We are part of the Faculty of Science at Leiden University.
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Photocleavable activity-based acid glucosylceramidase probes
Lysosomal acid glucosylceramidase (GBA1) is a lysosomal enzyme that degrades glucolipids with its main substrate being glucosylceramide (GlcCer). Defects in the GBA1 gene lead to glycosphingolipidosis Gaucher disease (GD), in which the hydrolysis of GlcCer is impaired and therefore, it accumulates in…
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Role of integrin adhesions in cellular mechanotransduction
Promotor: B. vd Water, T. Schmidt, Co-Promotor: E.H.J. Danen
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Human skin equivalents for atopic dermatitis: investigating the role of filaggrin in the skin barrier
Promotor: Prof.dr. J.A. Bouwstra, Co-promotor: Dr. A. El Ghalbzouri
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Toll-like receptor signaling in the innate immune system of zebrafish larvae
Promotor: H.P. Spaink, A.H. Meijer Co-promotor: R. Marin-Juez
- Green Infrastructure, Biodiversity and Ecosystem Services
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A community effort to assess and improve drug sensitivity prediction algorithms
Source: Nature Biotechnology, Volume 2014, Issue June (2014)
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Algorithms for the description of molecular sequences
Promotor: J.N. Kok, P.E. Slagboom Co-promotor: J.F.J. Laros
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Image-based phenotypic screening for breast cancer metastasis drug target discovery
The main aim of this thesis was to unravel the signaling and regulatory networks that drive tumor cell migration during breast cancer metastasis.
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Structural changes in single chromatin fibers induced by tension and torsion
Promotor: Prof.dr. T. Schmidt, Co-promotor: Dr. ir. S. J.T. van Noort
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Innovative strategies to clinically characterize the human tear proteome
Transplantation of labial salivary glands to the eyelids for patients with dry eye appears to give excellent results clinically.
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Controlling growth and morphogenesis of the industrial enzyme producer Streptomyces lividans
Promotor: Prof.dr. G.P. van Wezel, Co-Promotor: E. Vijgenboom
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Liver X receptor: therapeutic targeting of common pathways in Psoriasis and Cardiovascular co-morbidities
Both psoriasis and atheroslcerosis are diseases characterized by a chronic and systemic inflammatory profile with local lipid disturbances that alter the barrier function of the skin (psoriasis) and cause the development of atherosclerotic plaques (atherosclerosis).
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Ecology and genomics of Actinobacteria and their specialised metabolism
Filamentous Actinobacteria, such as Streptomyces, produce a plethora of chemically diverse bioactive metabolites that have found applications across medicine, agriculture and biotechnology.
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A community computational challenge to predict the activity of pairs of compounds
Source: Nat Biotechnol, Volume 32, Issue 12, pp. 1213-22 (2014)
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Next generation bacitracin: reimagining a classic antibiotic
Given the accelerating appearance of antimicrobial resistance, there is an urgent need for more fundamental research into novel antibiotic strategies. The work in this thesis helps to address this global problem by developing new antibiotic compounds, inspired by the antibacterial mechanisms of the…
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CAM-PaC
The overall aim of CAM-PaC is to contribute to solving the socioeconomic and health challenges of PDAC by an integrative and systematic functional analysis of pancreatic cancer candidate genes. CAM-PaC will develop novel cellular and animal models, as well as novel strategies to analyse and integrate…
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Mechanical and genetics basis of cellularization and serosal window closure in Tribolium castaneum
The applications of studying the early development of insects range from agriculture to material science.
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Carcinogenicity of insulin analogues
Promotor: Prof.dr. B. van de Water, Co-promotores: J.W. van der Laan, C.L.E. Siezen