1,257 search results for “mathematische biologie” in the Public website
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Maarten Lubbers
Science
m.lubbers@biology.leidenuniv.nl | +31 71 527 5075
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Chemical biology of glucosylceramide metabolism fundamental studies and applications for Gaucher disease
This thesis describes biochemical investigations of glucocerebrosidase (GBA), the lysosomal β- glucosidase that is deficient in Gaucher disease (GD).
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Chemical biology of glucosylceramide metabolism: fundamental studies and clinical applications for Gaucher disease
How can we develop new chemical biology tools and approaches to understand and interfere with glucosylceramide metabolism in relation to Gaucher disease?
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The use of activity based protein profiling to study proteasome biology
Promotor: H.S. Overkleeft, Co-Promotor: B.I. Florea
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Louie Krol
Science
l.krol@cml.leidenuniv.nl | +31 71 527 2727
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Kees Musters
Science
musters@cml.leidenuniv.nl | +31 71 527 7461
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Silva Nova – Restoring soil biology and soil functions to gain multiple benefits in new forests
We will study how inoculation of former arable land with soil (including the microbiome, soil fauna and seeds/rhizomes of ground flora) from old forests along with planting targeted tree species mixtures will improve productivity and more rapidly restore forest-adapted communities and ulttimately result…
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Chengyi Liu
Science
c.liu@cml.leidenuniv.nl | +31 71 527 2727
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Bregje Brinkmann
Science
b.w.brinkmann@cml.leidenuniv.nl | +31 71 527 7475
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Pieter Baas
Science
baas@nhn.leidenuniv.nl | +31 71 527 2727
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Edi Gittenberger
Science
e.gittenberger.1@biology.leidenuniv.nl | +31 71 568 4881
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August Martin
Faculty of Humanities
a.w.martin@hum.leidenuniv.nl | +31 71 527 2031
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context-based educational reform practical for implementatiion in Dutch biology education
For a successful implementation of an educational reform, teachers need to regard the proposal as being practical. I used a modular, success-oriented approach to make a context-based reform practical for implemtentation in Duthc biology education. educational reform, modular, teachers, biology, success-oriented,…
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Major European subsidy for Leiden evolutionary biology
Paul Brakefield, Professor of Evolutionary Biology at the Institute of Biology in Leiden (IBL) has been awarded an ERC Advanced Grant for his research. He will receive 2.5 million euro to develop his research programme over a period of five years.
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Unravelling cell fate decisions through single cell methods and mathematical models
Despite being the object of intense study, embryonic development has been difficult to model due to a number of reasons. First, complex tissues can be comprised of many cell types, of which we probably only know a subset.
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New IBL-professor in Ultrastructural Biology: Ariane Briegel
Ariane Briegel has been appointed Professor in the fìeld of Ultrastructural Biology within the Faculty of Science at the Institute of Biology from the 1st of December 2015. Her expertise is in using electron cryotomography to study how microbes sense and respond to their environment.
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Geert de Snoo
Science
g.r.de.snoo@cml.leidenuniv.nl | +31 71 527 2727
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Vincent Merckx
Science
merckx@nhn.leidenuniv.nl | +31 71 527 3570
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Fien Demuynck
Science
j.m.demuynck@biology.leidenuniv.nl | +31 71 527 5045
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Lina Bayona Maldonado
Science
l.m.bayona.maldonado@biology.leidenuniv.nl | +31 71 527 4791
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Daniel Zumel Gete
Science
d.zumel.gete@cml.leidenuniv.nl | +31 71 527 2727
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Anagnostis Theodoropoulos
Science
a.theodoropoulos@biology.leidenuniv.nl | +31 71 527 4882
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Peter van Welzen
Science
peter.vanwelzen@naturalis.nl | +31 71 527 2727
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Caitlin Black
Science
c.e.black@cml.leidenuniv.nl | +31 71 527 2727
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Niels Raes
Science
niels.raes@naturalis.nl | +31 71 527 2727
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Han de Winde
Science
j.h.de.winde@science.leidenuniv.nl | +31 71 527 1036
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Sam Boerlijst
Science
s.p.boerlijst@cml.leidenuniv.nl | +31 71 527 2727
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Hans de Iongh
Science
h.h.de.iongh@umail.leidenuniv.nl | +31 71 527 7461
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Teacher knowledge and lesson design
The studies reported in this thesis were situated in the context of an innovation of Dutch secondary school biology curricula. As in any innovation, the practical knowledge of teachers determine the outcomes through the decisions they make while planning and teaching their lessons. The aim of the studies…
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Top rating for Biology at Leiden University
Biology is one of the four top educational programs at Leiden University according to the national “Guide to Universities” (Keuzegids Universiteiten).
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Leiden biology appreciated with large NWO grants
A Vici grant and a Science-GROOT: scientists from the Institute of Biology Leiden have been awarded prestigious grants from the Dutch Research Council (NWO). From investigating bacteria without cell walls to harnessing plants with the help of microorganisms.
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Animal Sciences
We perform multidisciplinary research at molecular, cellular, and organismal levels of animal biology to increase fundamental understanding of health and disease.
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IBL symposium “Integrative Biology towards Healthy Communities”
On Monday the 8th of December, the annual symposium of the IBL will be organized at the main building of the LUMC Leiden. This year’s theme is “Integrative Biology towards Healthy Communities”.
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Computational, biochemical, and NMR-driven structural studies on histone variant H2A.B
Nature uses a special class of histone proteins, histone variants, to modulate the properties of chromatin at defined genomic locations.
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New IBL-professor in "Computational Biology": Vera van Noort
Vera van Noort has been appointed Professor in the field of Computational Biology within the Faculty of Science at the Institute of Biology from the 1st of February 2017. Van Noort’s expertise is in bioinformatics and her research focuses on the computational analysis of large-scale biological data…
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Hall of Fame 2023
In 2023, many of our students and staff won great prizes and secured important research grants.
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Record number of first-year students for Leiden Biology
150 new Biology students have arrived in Leiden. This is more than ever and we seem to settle among the big three Universities for Biology in the Netherlands.
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Ten million euros for unlocking novel technologies in structural biology
The European Union has invested ten million euros in the so-called iNEXT-Discovery consortium. The goal of this new consortium is to enable European researchers to extend innovative structural biology research. The Netherlands Centre for Electron Nanoscopy (NeCEN) is also part of iNEXT-Disovery, which…
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Visual analytics for spatially-resolved omics data at single cell resolution: Methods and Applications
The deeper understanding of an organism's pathology is important for developing treatments. Over centuries of systematic research, clinical researchers have demonstrated that the more information they acquire about the cellular properties and their organisation in the tissue, the better they can understand…
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Double success at the EMBL Chemical Biology Conference
Thomas Bakkum en Tom van der Wel, two PhD candidates from the Leiden Institute of Chemistry, have both won poster prizes at the EMBL Chemical Biology Conference 2018 in Heidelberg.
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Inaugural lecture: Big pictures of small microbes
Bacteria are everywhere. They are the most abundant organisms on earth and impact all aspects of our lives. They determine our health and shape our environment. Ariane Briegel, professor of Ultrastructural Biology, freezes bacteria super fast to gain a true-to-nature image of the internal and external…
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Delegation of Holland Rijnland visits the Institute of Biology
On Thursday the 24th of November, Tseard Hoekstra and Jeroen Ververs (members of the delegation Holland Rijnland), Geert de Snoo (Dean Faculty of Science), Martina Vijver (CML), Herman Spaink (Scientific Director IBL) and Klaas Vrieling (IBL) explored possibilities for collaborations between companies…
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Luka Narisha
Science
l.l.narisha@cml.leidenuniv.nl | +31 71 527 5615
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Marjolein Crooijmans
Science
m.e.crooijmans@biology.leidenuniv.nl | +31 71 527 5075
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Emily Strange
Science
e.f.strange@cml.leidenuniv.nl | +31 71 527 2727
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Lan Dupuis
Science
l.dupuis@cml.leidenuniv.nl | +31 71 527 2727
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Mathematics-based strategies for repairing tumour blood vessels
How does the extracellular matrix coordinate endothelial cell behavior during angiogenesis, and how do metabolic waste-products and matrix-degrading enzymes produced by the tumour modify the extracellular matrix so as the change the cellular coordination?
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Teachers’ practical knowledge and lesson design in the context of innovation
This project is situated within the context of an innovation of the biology curriculum in Dutch secondary schools. The main purposes are (1) to clarify the relation between teachers’ practical knowledge and the decisions they make when planning and implementing their lessons and (2) to develop a professional…
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Systems diagnosis of chronic diseases, explored by metabolomics and ultra-weak photon emission
Promotor: J. van der Greef; Co-promotor: E. van Wijk, M. Wang
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Chemical tools to study the cannabinoid receptor type 2
The cannabinoid receptor type 2 (CB2R) is associated with several inflammatory diseases with an unmet medical need (e.g. Alzheimers, multiple sclerosis, reumatoid arthritis). Development of new chemical biology strategies to study this protein is essential to aid future development of drugs for these…