Promotores: Prof.dr. H.P. Spaink & Prof.dr. P.C.W. Hogendoorn, Co-promotor: Dr. M.J.M. Schaaf

Worldwide resurgence of pertussis necessitates the need for improvement of pertussis vaccines and vaccination strategies.

The function of TLRs in innate immunity has aroused worldwide attention soon after its discovery. Because of the broad functions of TLR2 in innate immunity, the drive for the development of TLR2-targeted vaccines or therapeutic treatments has accelerated in the last decades.

Promotor: H.P. Spaink, A.H. Meijer Co-promotor: R. Marin-Juez

Michiel van der Vaart with a team from Leiden University and the LUMC, led by IBL-researcher Annemarie Meijer, discovered that DRAM1 is a protein that regulates anti-bacterial autophagy, a defense mechanism against infections such as tuberculosis.

Josien de Klerk and Tennessee Miller examined the interplay between students’ illness and recovery experiences and academic work culture in this context.

The cellular recycling system in zebrafish is capable of eating harmful bacteria and thus resist infections such as tuberculosis and salmonellosis. That is written by Leiden biologists from the group of Annemarie Meijer. Stimulating this form of defence could be used in new treatment methods against…

The opportunistic bacterium Burkholderia cenocepacia is feared by cystic fibrosis patients and is emerging in hospital-acquired infections. An international study sheds new light on the infection mechanism of this opportunistic pathogen that may have large implications for treatment strategies.

PhD defence

The infection rate is rising again in the Netherlands, which means it may also be rising among Leiden University’s students and staff. How is the University responding? And what dilemmas is it facing? We spoke to our Rector Magnificus, Chief Security Officer and two other administrators.

The silenced paradoxes of urban renewal.

The Seeger Center for Hellenic Studies at Princeton University annually offers a limited number of Visiting Research Fellowships for scholars in the humanities or the social sciences worldwide, who wish to spend time in residence at Princeton pursuing independent research projects, free of teaching…

Joost Beltman (LACDR, Leiden University) has provided novel insights in the way T cells migrate towards virus-infected cells. This was accomplished by a combination of experimental research in the group of Ton Schumacher (Dutch Cancer Institute, NKI) and computer simulations in collaboration with Rob…

In 1933, Maria Ulfah Santoso was the first Indonesian women to earn a law degree. During her studies in Leiden University she became involved with Indonesia;s nationalist movement. She went on to be Indonesia's Social Minister, as the first female cabinet member. In this article, historian Wildan Sena…

New drugs for use as tuberculosis (TB) treatment are needed due to the constrains of classical antibiotics against TB and the rise of antibiotic-resistant strains, making TB a harder and harder disease to treat.

Maria Vasile and Ola Gracjasz met in Donostia-San Sebastian, in the Basque Country, on the 7th of June 2022 to take part in the 1st Feminist Anthropology Conference in the Spanish state (I Antropologia Feminista Kongresua), and together present some of the outcomes of their Ph.D. researches. The conference,…

The project aims to explore the history of the concept “barbarism” in Europe from the 18th century to the present. Responding to the contemporary popularity of the term “barbarism” in political rhetoric and the media, and the lack of reflection on the implications and legitimacy of its use, the project…

Promotores: T. Hankemeier; R. Berger, Co-promotor: R.J. Vreeken

On March 31st – April 1st, the Association for the Study of Law, Culture and the Humanities (ASLHC) will hold its twentieth annual conference at Stanford Law School.

The research described in this thesis has, using the zebrafish as a model system, shed new light on the intricate relationship between TB and DM2, in particular on the role of leptin, SHP-1 and glucocorticoids.

Antimicrobial drugs constitute a fundamental part of modern medicine. The global rise in antimicrobial resistance poses a major threat to global health.

Maria discusses her case studies with a broader public

The Centro de Estudos Internacionais at Instituto Universitário de Lisboa (ISCTE-IUL) will host the

Health workers have always sought ways to fight disease in vulnerable groups in the population. It is now clear that such research also benefits more prosperous countries. African worm infections and innovative thermometers have shown Leiden researchers how to fight diseases of affluence and keep health…

IBL-researcher Phil Elks in the group of Annemarie Meijer won the Cell Observatory Publication of the Year 2013. He received the award for his paper in PLoS Pathogens, showing that activation of hypoxia signaling protects against mycobacterial infection.

The centre of our Galaxy is so dark and dense that it is almost impossible to observe what is inside. By catching the rare hypervelocity stars that are ejected from it, Elena Maria Rossi aims to unveil the mysterious environment around the supermassive black hole inside. But she’ll also be solving another…

The research described in this Thesis was aimed at designing and synthesizing nature-inspired compounds as part of TB vaccine discovery.

Of the 111 Spinoza Prizes that have been awarded since 1995, 28 have gone to researchers from Leiden University.