This doctoral research project in design seeks to shed a light on legibility in the context of visually impaired beginning readers.

To design the ideal water oxidation catalyst, understanding of the catalytic mechanism and decomposition pathways is essential.

Promotor: Prof.dr. T.H.W. Bäck

Huda Abi-Fares defended her thesis on 10 January 2017.

Promoter: J.G.E.M.Fraaije, Co-promotor: A. Kros

This dissertation explores new chemical strategies for the synthesis of self-adjuvanting peptide conjugates and immunomodulatory ligands aimed at targeted activation of the immune system.

Higher design and engineering educators have different views on what a new or renewed curriculum should entail, content-wise as well as pedagogically. This research aims to describe how these ‘curriculum perspective perceptions’ influence working definitions, end goal formulation, and the scope of results…

A modern ship design process is subject to a wide variety of constraints such as safety constraints, regulations, and physical constraints.

Multi-objective evolutionary computation aims to find high quality (Pareto optimal) solutions that represent the trade-off between multiple objectives.

Chapter 2 describes a post-synthetic methodology to introduce a fluorescent label in highly lipophilic, Pam3Cys based conjugates.

How can the concept of Critical Making be expanded into a general approach that ties the critical methodology of artistic research, and the established concepts of artistic autonomy, together with contemporary creative-technological development?

Promotores: J. Kok, M. Chaudron (Chalmers University)

Lecture

On 20 September 2023 Mark van de Water successfully defended a doctoral thesis and graduated.

Promotor: Huub J.M. de Groot, Co-promotor: Francesco Buda

How did common people write in the late eighteenth century? Little is yet known on this topic, since our knowledge is mainly based on printed texts written by a small part of the (male) elite population. This dissertation – written from a sociolinguistic point of view – gives us new insights into late-…

World History — a Genealogy charts the history of the discipline through twenty-five in-depth conversations with historians whose work has shaped the field of world history in fundamental ways.

Promotor: Prof.dr. E.F.A. Deprettere, Co-promoter: Todor P. Stefanov

Viral diseases constitute one of the major challenges in modern medicine. Membrane-targeting have broad-spectrum potential and could distinguish viral membranes from the host cell plasma membrane by the difference in membrane curvature.

This Thesis describes the design, synthesis and evaluation as glycoprocessing enzyme inhibitors of focused libraries of iminosugars.

This thesis describes the design, characterization and application of dextran based crosslinked network.

New and reemerging infectious diseases call for innovative and efficient control strategies of which fast vaccine design and development represent an important element.

On 30 June 2016, Eesa Fredericks is expected to defend his Ph.D.-thesis ‘Contractual Capacity in Private International Law’ in Leiden. Supervisors are prof. Sierd J. Schaafsma (Leiden) and prof. Jan Neels (Johannesburg).

On May 18 Janneke Wesseling gave a lecture at the conference

This project is situated within the context of an innovation of the biology curriculum in Dutch secondary schools. The main purposes are (1) to clarify the relation between teachers’ practical knowledge and the decisions they make when planning and implementing their lessons and (2) to develop a professional…

Anja Groten investigates matters of collectivity, drawing from the experience of working with the Amsterdam-based collective Hackers & Designers (H&D)*.

Tycho de Graaf has been appointed Professor of Technology and Private Law at Leiden University as of 1 June 2022.

This dissertation explores matters of collectivity, drawing from the experience of working with the Amsterdam-based collective Hackers & Designers (H&D).

The aim of this study was to provide insight into how teachers in higher education can be supported in the design, implementation and evaluation of group assignments by developing a theoretical and evidence-based framework for the design of group assignments.

The new book by Dimiter Toshkov - associate professor of Public Administration at the Faculty of Governance and Global Affairs - has been recently published by Palgrave Macmillan.

DSE 2.0 concerns research on DSE techniques for complex dCPS

The increasing competition in the automotive industry requires the tailored, swift development of technologically sophisticated vehicles. Therefore, the computationally expensive state-of-the-art simulation technologies are combined with optimization algorithms. An example of a real-world optimization…

Constraint multi-objective optimization with a limited budget for function evaluations is challenging. This thesis tackles this problem by proposing new optimization algorithms. These algorithms are applied on holistic ship design problems. This helps naval architects balance objectives like cost, efficiency,…

In order to analyze the challenges linked to data use in the context of nexus governance, Giest & Mukherjee use a policy design lens and more specifically the perspective of organizational policy instruments to look at the Mediterranean region.

Glycosidases are essential in fundamental biological processes and are responsible for the degradation of most (oligo)saccharides, glycolipids and glycoproteins.

Cathalijne van der Plas will become Professor of Private International Law (0.4 fte) at Leiden University as of 1 October 2021. She succeeds Prof. Sierd Schaafsma who has become a judge at the Supreme Court as of 1 May 2021.

The thesis describes the development, synthesis and biological evaluation of several proteasome inhibitor designs. Mainly, this work focusses on designing proteasome inhibitors that selectively inhibit the immunoproteasome, while leaving the constitutive proteasome mostly, if not completely, untouch…

The main subject of this thesis is the design and synthesis of paramagnetic molecules for protein studies with NMR and EPR spectroscopy.

On Friday 2 December 2016, an international, multidisciplinary Research Conference on “Private law and market regulation – interaction, interference or inconsistency?” will be held in Leiden, hosted by the Coherent Private Law research group of Leiden Law School. The conference will be focused on two…

In design optimization problems, engineers typically handcraft design representations based on personal expertise, which leaves a fingerprint of the user experience in the optimization data. Thus, learning this notion of experience as transferrable design features has potential to improve the performance…

Promotores: Prof.dr. T.H.W. Bäck, Prof.dr. M.R.V. Chaudron, Co-Promotor: M.T.M. Emmerich

What are the characteristics of impactful education for student application of inclusive design principles in design and technology programs?