Rather than one key and one strong lock, biology often uses tens or hundreds of weaker links to bind parts together, such as cells membranes. This allows for selectivity and also reversibility: the binding can also be undone. Researchers first caught this phenomenon using spheres or colloids, and published…

In an Advance Online Publication biophysicist John van Noort and others show using magnetic tweezers that DNA is folded in compliant helices of chromatin. This allows enzymes access to the DNA needed for gene expression. Van Noort's research group made the discovery in close partnership with researchers…

An all-optical transistor, a molecule-sized sensor and a new kind of single-photon source for quantum communication. All dreamed applications of fundamental physics that are one step closer thanks to Robert Smit. On 12 June, he defended his PhD thesis with distinction.

Gerard van Westen has been appointed full Professor or Artificial Intelligence and Medicinal Chemistry. This chair has been jointly created by the Leiden Academic Centre for Drug Research (LACDR) and the Leiden Institute of Chemistry (LIC) as part of SAILS, the university stimulus program in Artificial…

From a white leather armchair, on which Barack Obama once sat, Dean Michiel Kreutzer opened the academic year. This time not with visitors, but completely corona-proof via a live stream. In a homely setting, Kreutzer spoke with several guests, including Covid-19 researcher Thomas Hankemeier and brand…

Would you like to organise a session during the biggest multidisciplinary event in Europe - the EuroScience Open Forum (ESOF) conference - to be held in Leiden from 13 to 16 July 2022? If so, send us your proposal! Archaeologist Corinne Hofman is one of the driving forces behind the conference and…

An atomic vandal has finally been caught! Scientists from Leiden University and the Department of Energy’s SLAC National Laboratory have uncovered the mysterious cause behind the rapid corrosion of platinum electrodes. This breakthrough paves the way for more affordable green hydrogen production and…

The European Research Council has awarded ERC Consolidator Grants to four researchers from Leiden. These grants of up to 2m euros will enable them to continue and expand their research.

Leiden and Austrian researchers have succeeded in further uncovering how a plant cell passes on the growth hormone auxin in a directional manner to the next cell. Three proteins that cling together in a bunch appear to be essential for this important transport process. ‘This discovery solves a crucial…

Five of the new Medical Delta professors who now hold an appointment at multiple institutions are affiliated with Leiden University/LUMC. They are psychologist Andrea Evers and four LUMC professors.

Nine talented Leiden researchers have been awarded a Vidi subsidy by the Netherlands Organisation for Scientific Research (NWO). Vidis are intended for researchers with several years of research experience who want to set up or expand their own line of research.

What dose of medicine do you give a child? That depends to a large extent on how quickly their kidneys remove the drug from the blood. For ethical reasons it is impossible to measure this directly in little patients. PhD candidate Sinziana Cristea combined different types of modelling and lots of data…

Sjaak Neefjes, Professor of Chemical Immunology at Leiden University, will receive the NWO Spinoza Prize this year. The Spinoza Committee called Neefjes an ‘exceptional researcher whose intelligence is matched by his boldness’. He will use the 2.5 million euro prize to pursue his research into cancer…

For medical research, researchers often recreate tissue in the lab. Organ-on-a-chip technology emulates organs, right down to the blood that flows through them, thus creating a realistic test model for drugs or research into disease processes. Researchers from the LUMC are coordinating an NWO Gravitation…

Environmental scientists Stefano Cucurachi and Paul Behrens and astronomer Jorryt Matthee have received prizes during the New Year's reception of the Faculty of Science on Tuesday 8 January. In addition, Kavli Prize winner Ewine van Dishoeck announced a new award.

Tuberculosis stands as one of the most lethal infectious diseases worldwide. A significant challenge in combatting tuberculosis lies in the emergence of antibiotic resistance triggered by genetic alterations, commonly known as mutations. These mutations can diminish the responsiveness to antibiotics,…

From artificial intelligence to letters from the Dutch East Indies and from breast-cancer gene BRCA-1 to the collaboration between government and opposition: nine researchers from Leiden University have been awarded a Vidi grant for their research.

The European Research Council (ERC) has awarded an Advanced Grant to six Leiden researchers. It awards these significant grants to established principal investigators for ground-breaking, high-risk research.

Two bacterial species team up inside the plant root system to rescue their host from fungal infection. This was discovered by a team of microbiologists and bioinformaticians from the Netherlands Institute of Ecology, Wageningen University, and the Institute of Biology Leiden. They also identified the…

The electrochemical reduction of a group of organic compounds on platinum is strongly dependent on the arrangement of the atoms in the platinum surface. Christoph Bondue, postdoc in Marc Koper's group, published this in Nature Catalysis on 4 March. The reduction of such compounds is an important process…

An international team of researchers, including Federico Calle-Vallejo of Leiden University’s Institute of Chemistry, have taken the atomic-scale design of catalysts to the next level. Their research contributes to the quest for a method to generate or store energy more efficiently. The report is published…

Leiden University will be conferring three honorary doctorates in its special anniversary year. They will be awarded to Eliot Higgins, truth finder and founder of Bellingcat, Bonnie Honig, expert in feminist theory and legal theory, and Kelly Chibale, professor of organic chemistry, who works on prevention…

A public symposium was held at Leiden University on 20 February on a hot topic: renewable energy. This is the second time in a year that the University has organised such a symposium. The previous one, about Artificial Intelligence, was a big success.

The title of European City of Science was officially handed over to a delegation from Leiden in the Italian city of Trieste on 6 September. Leiden will be the science capital of Europe for the year 2022. The EuroScience Open Forum (ESOF), the largest interdisciplinary science conference in Europe, will…

Designing innovative algorithms, thinking outside the box, and brainstorming over coffee with his colleagues — this is what physicist Stefano Polla enjoys most. His success shines through in his nomination for the C.J. Kok Jury Award 2024 for PhD thesis of the Year.

A group of single-celled organisms organises its DNA in a similar way to higher organisms such as plants, animals, and fungi. However, the way packaged DNA is read out differs between the two related groups, Bram Henneman discovered. PhD defence on 5 December.

Ten Leiden researchers have been awarded a Veni grant by the Dutch Research Council (NWO). The grant, of up to 280,000 euros, will enable them to elaborate their ideas over a period of three years.

Leiden PhD researcher Karin Öberg is one of the 17 winners of the NASA Hubble Fellowship. When she has obtained her PhD this autumn she will move to the United States for three years to conduct post-doctoral research into the role of ice in star formation.

Physicist Marileen Dogterom is one of the winners of the Spinoza Prize 2018. She is a professor at TU Delft, where she has her lab, and is also affiliated to Leiden University as a Medical Delta Professor. She receives the prize for her research on the skeleton of the cell.

Three speakers, three fascinating science stories and a well-filled lecture hall. The Niko Tinbergen Lecture had a successful restart on 10 December 2019.

Director General of ESO, Tim de Zeeuw received President of the Republic of Chile, Michelle Bachelet Jeria for a ceremony marking the first stone of ESO’s Extremely Large Telescope (ELT).

Several consortia in which Leiden University is involved have been awarded Dutch Research Agenda funding. Leiden is the coordinator of five of these consortia. These five consortia will receive grants worth a total of almost 24 million euros. They relate to interdisciplinary projects that will bring…

Astronomers and surgeons from Leiden are collaborating with industry to develop an optical instrument that delivers faster, more accurate imaging of tumour tissue and abnormal blood flow during surgery.

Liposomes – nano-sized spheres composed of fatty molecules – are very promising for vaccination. Bio-pharmaceutical scientist Naomi Benne discovered that the immune response in animal models can be steered by varying the charge of the liposomes. She obtained her PhD degree on 8 September for this research,…

Pharmacist-clinical pharmacologist Robert Rissmann has been appointed Professor of Translational Dermatology. This extraordinary professorship has been created jointly by the Leiden Academic Centre for Drug Research (LACDR) and the Centre for Human Drug Research (CHDR) to strengthen their partnership…

From bedtime stories about mathematics to podcasts about microplastics and games on weeds: master students from the Science Communication & Society track presented the real-life products they developed during their final presentations on 20 December. Many of the products are already implemented by c…

How do you ensure that a drug has an effect on the right protein – and nothing else? Chemist Anthe Janssen explored various methods for determining the selectivity of potential medicines. He also looked at the substance BIA 10-2474, after a man died in a French clinical trial in 2016. PhD defence on…

Four researchers from Leiden University will receive funding from arthritis foundation ReumaNederland over the next five years. This should facilitate long-term research into arthritis.

Researchers and clinicians at Leiden University Medical Centre (LUMC) are about to begin a milestone clinical study. It will be the first time a stem cell gene therapy developed in the Netherlands is used in a clinic. The therapy will be used to treat children with SCID, a rare disorder where children…

Fourteen women professors are to be given a place in the classic portrait gallery in Leiden University’s Senate Chamber. The portraits will be unveiled on 8 March – International Women’s Day – by former Minister of Education, Culture and Science Jet Bussemaker and Rector Magnificus Carel Stolker.

A tenacious postdoc researcher persuaded Professor Marc Koper to research the oxygen reduction reaction. In Koper's eyes, there was little of interest there. But they promptly discovered a whole new way to improve fuel cells on hydrogen and oxygen. Their article appeared in Nature Catalysis on 07 Ju…

Stacked layers of graphene can act like a mirror for beams of electrons. Physicists Daniël Geelen and colleagues discovered this using a new type of electron microscope. In an article in Physical Review Letters, they describe their results, which could lead to the development of optics for electron…

Simulations of galaxy formation provide much more information about galaxies than a telescope. Simulations have been improving significantly in recent years. Astronomer Evgenii Chaikin made such a significant contribution to this field that he graduated with honours on February 27th.

By measuring proteins in tears, ophthalmologists can more easily diagnose dry eyes (Dry Eye Disease). Peter Raus, a Belgian ophthalmologist and PhD student at the Institute of Biology Leiden, developed a new method for protein determination in tear fluid. The technique is also promising for the early…

Thousands of first-year students and hundreds of mentors kicked off the EL CID on Monday morning. This year for the first time, the introduction week of Leiden University and Leiden University of Applied Sciences was also open for students of Regional Training Centre mboRijnland and the Leiden Instrument…

On the 19th of May 2020, our dear colleague and friend Professor Dr. Huib Ovaa has passed away from prostate cancer. Last summer Huib became ill, and in first instance it appeared that he had attracted a relatively harmless infectious disease. Unfortunately, it became soon apparent that he suffered…

Cramming from a book, making notes or learning summaries. In the past these were about the only ways to memorise your course material. But that has long since changed. Multimedia is the code word. But is it effective?

During the Faculty of Science New Year's reception, Daniël Rozen was named Discoverer of the year 2015. Nienke van der Marel and Koen van der Maaden both won the prize for the best dissertation and Jeroen van Smeden was named Best Teacher of 2015.

Those pesky raindrops that get you wet on your way to work, are formed high up in the sky from clouds of water vapour. The process of nucleation describes the way this happens. Edgar Blokhuis of the Leiden Institute of Chemistry developed a theory to describe this transition more precisely. Chemists…

The prestigious journal Science Translational Medicine has published a study by researchers from the Institute of Biology Leiden (IBL) on a potent new antibiotic that can overcome resistance. ‘The idea was to tweak the original antibiotic and create a next-generation drug’, says Nathaniel Martin, professor…