PhD candidate Maia Casna received an Incentive Prize from the Dutch Association for Physical Anthropology (NVFA). She was rewarded this honor for her innovative research into respiratory diseases and her talent for presenting her results to both academic and general audiences. ‘It feels really nice…

LUMC and Leiden University will start the new two-year online master's program in Transfusion Medicine and Cellular and Tissue Therapies from October 2023.

Despite considerable progress in the design of multifunctionalized nanoparticles (NPs) that selectively target specific cell types, their systemic application often results in unwanted liver accumulation. The exact mechanisms for this general observation are still unclear.

One of our PhD candidates at the LACDR, Joey Zuijdervelt, recently achieved recognition by winning the first prize in the ‘Schild-De Groen Onderzoeksprijzen’ for cancer research. His award-winning master’s thesis explored glioblastoma multiforme through an innovative orthotopic zebrafish xenograft model,…

Tuberculosis bacteria survive by hiding in our immune cells. In her PhD research, biologist Salomé Muñoz Sánchez explores how boosting the body’s own defenses might outsmart this deadly pathogen. Her work reveals two key proteins that help immune cells destroy the bacteria.

Before researchers can develop targeted drugs, they need to know exactly how a disease works. Biochemist Bert Beerkens created molecules that allow them to find out. He used caffeine as the basis for new molecules that enable research into certain receptor proteins on cells.

Joey Zuijdervelt

More than 700 visitors got to know the Science Faculty during the Leiden Science Family Day. People of all ages could enjoy fascinating experiments, tours, interesting lectures, spectacular nitrogen shows and various workshops. It was an informative day with many (future) scientists, amazement and,…

Researchers from Leiden University Medical Center (LUMC) and the Leiden-based biotech company Ncardia have joined forces to develop a new platform that enables the automated production of 3D cardiac microtissues. This platform will allow large numbers of drugs to be tested quickly

Good research means looking beyond disciplinary boundaries, said Professor of Molecular and Cellular Biochemistry Remus Dame in his inaugural lecture on 10 May. Processes that take place on DNA shouldn’t only be researched in a test tube but also in living cells, for instance.

Research Director Judy Veldhuijzen, who started her new role this month, answers questions from colleagues. What is her vision for the institute? How does she view open leadership? And: how healthy is the GMN researcher herself?

Nano-plastics cause malformations. Meiru Wang, researcher at the Institute of Biology Leiden, looked at the extreme effects polystyrene nano-particles could have, using chicken embryos as a model. Her results were quite alarming. Especially as nano-particles are everywhere. In the air, floating through…

Researchers from Leiden University Medical Center (LUMC) have discovered how malaria parasites escape the immune system of mosquitoes. The so-called QC enzyme changes proteins on the outside of the malaria parasite such that the immune cells are unable to recognise the parasite. As a result, the parasite…

How do cells repair their damaged DNA—and what happens when that process is hindered and cancer arises? Sarah Moser has taken a closer look during her PhD, uncovering surprising insights that could help improve future cancer treatments.

Postdoctoral researcher Joost de Moor, who joined the interdisciplinary Global Transformations and Governance Challenges (GTGC) initiative at Leiden University since April 2021, will spend 50% of his time doing research for the project "The necessary and the possible: How social movements articulate,…

Koen Keijzer combined three mathematical models into one unified system capable of making meaningful predictions about how cells form blood vessels. This helps biologists studying the chaotic, leaky blood vessels found in and around tumours.

Since its discovery thirty years ago, it remained a mystery: how does the body’s own marijuana move between nerve cells in the brain? Mario van der Stelt and his research group have now uncovered the answer. This insight could aid the development of new treatments for pain and neurological disorders…

Five projects with researchers from Leiden University have received a grant from the Dutch Research Council (NWO) to build or upgrade existing research facilities.

Four Leiden researchers have been awarded Proof of Concept grants by the ERC. These grants, each worth 150,000 euros, help researchers translate the findings of previous ERC projects into innovative practical applications.

Four researchers from Leiden University have been awarded NWO Open Competition grants in the Science domain. This is for research into subjects such as immune cells in tumours, antibiotic resistance and magnetic semiconductors.

Cancer immunotherapy represents a significant breakthrough in cancer treatment. However, tumors have numerous mechanisms by which they evade destruction by the immune system. It is therefore necessary to decipher and reverse these mechanisms in order to improve immunotherapies.

Sebastian Pomplun receives an ERC starting grant of 1.85 million Euros in five years. He wants to develop synthetic transcription factors that can enter cells and activate or deactivate specific genes. For example to disrupt cancer-related processes or to trigger the production of an important missing…

From 11-13 July 2022, the 10th EMBRN International Mast Cell and Basophil Meeting took place in the Utrecht University Academia Building in Utrecht. During this meeting, novel insights and developments in the field of mast cell and basophil biology in both health and disease were shared.

In brain diseases such as Parkinson's and Alzheimer's, proteins clump together to form fibres. ‘Chaperone proteins’ unravel those fibres, but in the test tube biochemist Anne Wentink saw that this can also cause new problems. She is going to find out what happens inside cells to determine what a drug…

The Dutch Research Council (NWO) has awarded Vidi grants to 14 Leiden researchers. This grant of a maximum of 850,000 euros will enable them to start a new research group and develop their own line of research over the next five years.

During the 6th edition of the Graz Expert Meeting on Single-cell sequencing technologies in the cardiovascular field, held on September 15 and 16 in Graz, Austria, Jill de Mol from the group of Dr. Amanda Foks from the Division of BioTherapeutics received the award for best poster presentation.

From malaria parasites as a vaccine to how top-level bureaucrats reach their decisions: seven researchers from Leiden University have received a Vidi grant from the Dutch Research Council (NWO). This 800,000-euro grant will enable them to develop their own innovative line of research over the next five…

How do organs work in the body, and how can we create mini-organs to study diseases and test new medicines? That’s the idea behind organ-on-a-chip technology. During his PhD, Flavio Bonanini worked on developing the best possible mini-livers. ‘Make them as simple as possible, and as complex as neede…

Three fundamental research projects at Leiden in physics, chemistry and medical science have received funding from the Dutch Research Council (NWO). They involve research on magnetic fields in the universe, the role of myeloid cells in cancer immunotherapy and the evolution of ancient proteins.

Modified viruses can both kill cancer cells and activate the immune system. This is what an LUMC team discovered while researching a new prostate cancer therapy.

The winner of the 2022 Spring edition of the NWO Venture Challenge was announced during the Dutch Biotech Event. The innovative startup Iprotics has developed specific proteasome inhibitors that potentially treat multiple myeloma (MM) without the side-effects known from traditional proteasome inhibi…

Jasper Knoester is the dean of the Faculty of Science. How is he doing? What kinds of things is he doing and what does his day look like? In each newsletter Jasper gives a peek into his life as dean.

The theme of the Heritage Open Days Leiden on 10 and 11 September is sustainability. At four University locations guides will talk about the history of the buildings and how they have been renovated. And there is a first: tours in sign language.

Why is water wet? What is ADHD? In De Hoe?Zo! Show, curious 9-and-10-year-olds get answers to their questions. PhD candidates take to the stage to demonstrate just how exciting science can be while enhancing their own communication skills at the same time.

Children in the Netherlands develop prejudices based on ethnicity at an early age. Ymke de Bruijn (27) came to this conclusion in her dissertation ‘Child Interethnic Prejudice in the Netherlands: Social Learning from Parents and Picture Books’. For her PhD project she took a closer look at the behaviours…

Jasper Knoester is the dean of the Faculty of Science. How is he doing, what exactly does he do and what does his day look like? In each newsletter, Jasper gives an insight into his life.

Defending your PhD research in front of nearly 300 elementary school students: that was the challenge faced by PhD candidates Jo-Anne Verschoor and Marinka de Willigen during the VUURVLIEGEN competition organised by the Centrum JongerenCommunicatie Chemie (C3). After an exciting competition, the children…

PhD candidate Alex Tutwiler, from the Faculty of Archaeology, has received a grant from Archol, via the P.J.R. Modderman Foundation, to investigate how child labor shaped the bones of Dutch children between the 17th and 19th centuries. Using CT scans, she aims to build a more comprehensive picture of…

Sarah Cramsey, Special Chair for Central European Studies and Assistant Professor of Judaism and Diaspora studies, recently received an ERC grant for historical research into early child care in Central and Eastern Europe. In this short interview, she will give some more information on her grant, her…

Gaan vaders minder werken als andere vaders dat ook doen? Helpt betaald ouderschapsverlof hen om meer op te pakken in het huishouden? Hoe bepalend zijn sociale normen voor verschillen op de arbeidsmarkt? Onderzoeker Max van Lent gaat het uitzoeken.

From medicines from snake venom to supercrops and the origin of words. Thirteen researchers from Leiden University will receive Open Competition XS grants from the Dutch Research Council (NWO).

The risk of a brain tumour recurring can be predicted more accurately by counting the number of immune cells in the tumour under a microscope. These are the findings from research conducted by LUMC, Erasmus MC and Heidelberg University.

Ten Leiden researchers have been awarded a Veni grant by the Dutch Research Council (NWO). The grant, of up to 280,000 euros, will enable them to elaborate their ideas over a period of three years.

Rather than one key and one strong lock, biology often uses tens or hundreds of weaker links to bind parts together, such as cells membranes. This allows for selectivity and also reversibility: the binding can also be undone. Researchers first caught this phenomenon using spheres or colloids, and published…

To inhibit proteins that contribute to the growth of aggressive cancer cells, that’s the plan of Professor Bob van de Water and his team. They will receive over 700,000 euros from the KWF Dutch Cancer Society for their research. Researcher Maaike Vreeswijk and pathologist Danielle Cohen are affiliated…

Is it a coincidence that three chemists from the same department have each independently received a ZonMw grant? 'No,' the researchers agree in unison. 'The role of chemistry in medical biology is becoming increasingly important, and we’ve worked hard to make this happen.'

Three researchers from Leiden University have been awarded a Starting Grant by the European Research Council. The subsidy will allow the researchers to set up their own projects and put together a research team.

Researchers at Leiden University have created a unique model that mimics how disease develops after a dengue infection. This 'dengue-on-a-chip' model helps them study the virus more effectively. The timing is crucial, as climate change is causing dengue to spread worldwide.

With the aid of physics and a minuscule magnet, researchers have discovered a new structure of telomeric DNA. Telomeres are sometimes seen as the key to living longer. They protect genes from damage but get a bit shorter each time a cell divides. If they become too short, the cell dies. The new discovery…

Mini organs-on-chips allow us to study how diseases develop and how drugs work. Although the technology is not new, it is becoming increasingly advanced. PhD candidate Bart Kramer hopes it will eliminate animal testing in the future.