832 search results for “genetics” in the Public website
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Drug research
In the Drug Research theme, we primarily work with rodents. Rodents, such as mice, are one of the most common laboratory animals. These small mammals are easily housed and exhibit a rapid rate of reproduction.
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Career prospects
Completing your Master’s in Biology gives you an internationally recognised degree which you can follow up with a PhD track. With your acquainted skills, you’re a much requested professional in and outside research.
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Cognitive and motivational components of adaptive and maladaptive decision-making: an integrative approach
How do cognitive, motivational, and affective processes interact to select actions?
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About the programme
The two-year Bioinformatics programme (120 EC) includes mandatory core courses and electives, as well as a Master's Thesis Research Project. PLEASE NOTE: The specialisation Bioinformatics will no longer accept new students after February 2026. If you're starting date is September 2026 or later, we…
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Beneficial model microbial community: omics insights into plant growth promotion
Using EcoFab 2.0 devices and omics services at JGI, we will examine a plant growth promoting microbial community during interaction with different plant species.
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Hominin Evolution in Africa
The Great Rift Valley in Africa is a real treasure trove for discovering early human fossils. The fossils found in this part of Africa have determined our view of human evolution. But was the Great Rift Valley really the place where evolution took place or just a place where fossils are well preserved…
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Coming of age: An insight into the mechanisms of developmental ageing and post-harvest senescence in lettuce
The vegetative growth period for leafy vegetables like lettuce is essential for yield and quality.
- Biodiversity and the Anthropocene
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Extra-curricular
Are you interested in taking up an extra challenge during your master’s programme? Have you thought about developing your personal leadership style?
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The impact of non-genetic factors on drug metabolism: towards better phenotype predictions
PhD defence
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Advanced synthetic biology tools for genetic modification of human stem cells and their applications
PhD defence
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Identification of genetic determinants of kidney function and chronic kidney disease
PhD defence
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Research
Research in the POD-group addresses all features of random phenomena – modelling, structuring, analysis, control, optimisation – and covers both fundamental and applied aspects.
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Hall of Fame 2022
In 2022, many of our staff and students won fantastic prizes and were awarded important research grants.
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LIBC Sylvius Lectures
Our lectures are open to anyone with an interest Find your inspiration for interdisciplinary research
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Chemical tools to monitor and control human proteasome activities
Promotores: H.S. Overkleeft; G.A. van der Marel Co-Promotor: B.I. Florea
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Exploitation of host chemokine signalling by pathogenic mycobacteria
Promotores: A.H. Meijer, H.P. Spaink
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The Impact of Name Writing on Early Literacy
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Resolving plant transformation recalcitrance by Agrobacterium mediated protein translocation
Agrobacterium-mediated transformation (AMT) has abundantly been used for scientific research for identifying valuable traits.
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Career preparation
Leiden University offers you several services related to career orientation and job application skills.
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Applied Mathematics (MSc)
The master's specialisation Applied Mathematics at Leiden University focuses on both computational and fundamental aspects of analysis and probability. It’s also an ideal basis for a PhD degree. Applied Mathematics is an excellent choice if you have the aspiration to pursue a PhD degree
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Dynamic organization of bacterial chromatin by DNA bridging proteins
Bacteria often experience external challenges, such as changes in environmental conditions or attacks by bacteriophages.
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Unravelling East Africa’s Early Linguistic History (LHEAf)
This project investigates the rich linguistic history of the crucial language groups in East Africa and includes a search for words that indicate earlier lost languages. These outcomes, combined with recent archaeological and genetic research, will contribute to a new understanding of East Africa’s…
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‘Tell them if they race-mix, they will rot in hell’: right-wing extremists’ narratives on children’s ideological socialisation
This research examines how right-wing extremist parents perceive and discuss their role in the ideological socialisation of their children.
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The 3Generation study: Stress and Emotions in a Family Context
What is the role of neuronal emotional reactivity in the intergenerational transmission of abuse?
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Illuminating N-acylethanolamine biosynthesis with new chemical tools
In this thesis, the discovery and optimization is described of chemical tools to study the N-acylethanolamine (NAE) biosynthetic pathway.
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MicroClock: The Bacillus subtilis circadian clock, from molecules to mutualism
The central aims of MicroClock project are to describe the B. subtilis circadian clock at molecular and functional levels, and discover the mechanisms of clock-regulated bidirectional signaling between B. subtilis and the model plant Arabidopsis
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Regulation of actomyosin contraction as a driving force of invasive lobular breast cancer
In this thesis, we used genetically engineered mouse models and a variety of cell-culture based assays to identify genes and pathways that are involved in the development and treatment of invasive lobular carcinoma (ILC).
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A grammar of Ik (Icetod) Northeast Uganda’s last thriving Kuliak language
This study offers a comprehensive but balanced grammatical analysis of Ik (Icetod), Northeast Uganda’s last thriving Kuliak language.
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spFRET studies of nucleosome dynamics modulated by histone modifications, histone variants and neighboring nucleosomes
Promotor: Prof.dr. T. Schmidt, Co-Promotor: Dr. ir. S.J.T. van Noort
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In vivo tracking and biodistribution of protein aggregates
Therapeutic proteins have revolutionized the treatment of many severe diseases like multiple sclerosis, haemophilia, diabetes and many more. Unfortunately, even recombinant proteins with structures (almost) identical to those of their endogenous counterparts often induce the formation of anti drug antibodies…
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Quality-driven multi-objective optimization of software architecture design: method, tool, and application
Promotores: Prof.dr. T.H.W. Bäck, Prof.dr. M.R.V. Chaudron, Co-Promotor: M.T.M. Emmerich
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eDNA Citizen Science
How can we track biodiversity loss at the speed and scale needed to protect our ecosystems? The eDNA Citizen Science project combines cutting-edge environmental DNA technology with citizen science to enable residents, community groups, and local organizations to monitor aquatic and terrestrial biodiversity…
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Discovery of novel Antibiotics from Actinomycetes by Integrated Metabolomics & Genomics Approaches
Promotor: G.P. van Wezel, Co-promotor: Y.H. Choi
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Cell-autonomous and host-dependent CXCR4 signaling in cancer metastasis: insights from a zebrafish xenograft model
Promotor: A.H. Meijer, Co-promotor: B.E. Snaar-Jagalska
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The First Horse Herders and the Impact of Early Bronze Age Steppe Expansions into Asia
The article investigates the origins of Indo-European languages in Asia by 65 coupling ancient genomics to archaeology and linguistics.
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A Grammar of Konso
This dissertation provides a description of Konso, a Cushitic language spoken by about 250,000 speakers in the South-West Ethiopia.
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Azafaros is valorizing a library of compounds
The company Azafaros was established in 2018 to translate innovative science from Leiden University and Amsterdam University Medical Center into novel disease-modifying treatment modalities for rare genetic metabolic disorders such as lysosomal storage diseases.
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Ecology-based discovery of novel antimicrobials from rare Actinobacteria
Uncover novel antimicrobials with prospective health benefits for sea turtles.
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Vision
The Pharmacy research group focusses on the development of predictive models to improve clinical drug efficacy and safety. We work on clinical problems that require further mechanistic understanding and strive for ultimate benefit to patients.
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Microbial footprints of tomato domestication
Although plant domestication has significantly altered crop genetics and phenotypes, its effects on the taxonomic and functional diversity of plant-associated microbiomes are not well understood.
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Activity-based protein profiling in drug discovery
In the last decades, activity-based protein profiling (ABPP) has emerged as a powerful chemical tool that may aid the ever-challenging drug discovery process.
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Hybrid zone movement
Does a moving hybrid zone leave a genomic footprint?
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Bioactive Molecules in Microbial Sciences
Microbial Sciences' contribution to the Bioactive Molecules research theme is to discover new bioactive molecules and enzymes and unravel their mechanisms of action, regulatory networks, and the (bio)synthetic pathways required for their production.
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Targeted Therapy for Triple-Negative Breast Cancer
The research described in this thesis focused on identifying novel drug targets and synergistic combinations for triple-negative breast cancer (TNBC), a virulent subtype of breast cancer with a dismal prognosis and limited therapeutic options.
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Explant cultures of atopic dermatitis biopsies maintain their epidermal characteristics in vitro
Atopic dermatitis (AD) is a common inflammatory skin disorder characterised by various epidermal alterations. Filaggrin (FLG) mutations are a major predisposing factor for AD and much research has been focused on the FLG protein.
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Comparative Indo-European Linguistics
Reconstructing language history and prehistory in the context of the Indo-European language family.
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Microbial Sciences
In Microbial Sciences, we perform multidisciplinary research to understand the structure and function of microbes at all levels of biological organization, from small molecules and cellular structures at atomic resolution to multicellular communities.
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INFLANET - Training European Experts in Inflammation: from the molecular players to animal models and the bedside
How is inflammation in tuberculosis controlled by interplay between autophagy and inflammasome signalling?
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MtDNA Barcoding Invasive Species
What is the provenance of introduced populations?