Repairing organs, tissues and cells to fight chronic diseases.

Improving health, enhancing well-being and reducing health disparities across society.

How is inflammation in tuberculosis controlled by interplay between autophagy and inflammasome signalling?

This project focuses on a striking parallelism between two macro-groups of languages: southern Italian dialects and the so-called split-ergative languages, like Basque, Georgian, Dyirbal, Hindi/Urdu.

A master's degree in Psychology at Leiden University combines theoretical knowledge with academic and professional skills, making you an attractive candidate for many employers. However, there are far more graduates than vacancies, especially in mental health care, and competition is therefore fierc…

Lecture

A recent publication by Biopharmaceutics PhD-candidate Eva Kritikou has been accepted by the renowned scientific journal Scientific Reports.

Perec’s Lieux project consists of texts describing the author's places of memory, photographs, personal documents and ephemera collected in the street.

Frans Preumayr's nineteenth century virtuosic bassoon repertoire - An approach with a fine Grenser & Wiesner bassoon from Dresden: Issues of material and technique

Retrospection over the last 40 years the most important changes in care and research, where transparency accountability and guidelines became leading. On Huntington’s disease and cerebrovascular disorders the most important changes are illustrated.

It is difficult to deny the value and importance of human rights, and yet their application in the context of climate change is increasingly contested. While some argue that it is difficult to establish the violation of human rights by climate change processes, others contend that human rights are anthropocentric,…

On Wednesday 23 October 2024 Yixiu Jiang successfully defended a doctoral thesis and graduated.

We invite proposals for workshops and tutorials, to be held in Leiden on 01 July 2024 (deadline passed).

Why do historians so often talk about objectivity, empathy, and fair-mindedness? What roles do such personal qualities play in historical studies? And why does it make sense to call them virtues rather than skills or habits?

Climate finance, especially for developing countries, is crucial for limiting global warming to 1.5C. However, the current level of North -South climate finance is chronically inadequate. As the climate crisis intensifies, more actors are entering the climate finance market, transforming the global…

The subject of the research is ‘difference and repetition’, an area which bears a direct relationship to Wjm Kok’s practice, in which the production of work always emerges and passes through series.

Each year, this award spotlights a standout bachelor’s graduate whose thesis truly rises above the rest. Here you’ll learn how the selection works and where to find the talented students who claimed the title in previous years.

On Wednesday 3 July 2024 Renata Schiavo successfully defended a doctoral thesis and graduated.

If you want to continue your academic education, the logical next step after obtaining your bachelor’s degree is to follow a master’s. You can do so in a university inside or outside the Netherlands, including several options right here at Leiden University!

The Graduate School of Social and Behavioural Sciences in collaboration with the Department of Methodology and Statistics and researchers in the field of Methodology and/or Statistics of the other Institutes provides training courses for PhD candidates and other researchers.

Lecture, Talk

The Institute of Psychology is responsible for innovative and interdisciplinary research and education within psychology and related disciplines.

An overview of the research at the Cancer Dug Target Discovery group.

Treatment and care for cancer patients is becoming increasingly advanced. For example, surgeons can now perform operations with much greater precision, and therapeutic vaccines are being developed to prompt the patient’s immune system to fight cancer. Work is also being done on better early diagnostics,…

In this research group, headed by Bob Van de Water, cell signaling programs that underlie adverse drug reactions as well as cancer development and progression are unraveled. Adverse drug reactions involve cell injury in critical target organ cells which leads to the activation of cellular stress response…

This project has two main aims: I. Determine when novelty promotes fear extinction. II. Discover the neurobiological mechanisms underlying these effects.

In this research group, led by Dr. Joost Beltman, the aim is to employ mathematical and computational dynamical modelling approaches in order to quantitatively and mechanistically understand the dynamical behaviour and regulation of intracellular networks of genes, proteins and metabolites as well as…

Our immune system protects us against disease, but every now and then, something goes wrong: an enemy invades our bodies or our immune system attacks our own cells and we become ill. Doctors and researchers at the Leiden University Medical Center (LUMC) want to be able to manipulate the immune system…

The goal of hit and lead optimization is to optimize suitable chemical starting points that can modulate a drug target. The methods and technologies used are similar to those in Hit Discovery, but once the compound has shown activity in an animal model, it moves from 'hit' to 'lead.'

What are the developmental pathways to social anxiety (disorder), the causal processes and maintaining factors? How do these factors interact in the development of social anxiety disorder? How can this knowledge be used to design and implement effective preventive intervention programs for youth?

The aim of this project is to investigate the (cost)effectiveness of two innovative forms of trauma-focused therapy for patients with childhood abuse related PTSD. The ultimate goal is to improve quality of care and contribute to treatment innovation for this severely ill target population.

Social anxiety disorder is one of the most common disorders in children and young people. Social anxiety is characterized by excessive fear and avoidance of social situations. The primary fear in children with social anxiety is that they will be negatively judged by others. To date, the most frequently…

The mission of Software and AI in Business (SA&B)connects the domains of science, business, and policy. Scientific research we focus on at Leiden in areas such as artificial intelligence promises to reshape our societies for the better. Translating science into positive societal impact however requires…

Can excessive worrying be reduced via stimulation of the vagus nerve?

This research area is focused on the development and application of novel concepts and models in the emerging area of quantitative systems pharmacology (QSP).

The study aims (1) to track progressive changes over time in trainees, and (2) to identify influences that facilitate or impede trainee development. Systematic information will be gathered on the characteristics of trainees and training programs, focusing particularly on trainees’ experiences in clinical…

Although rarely considered by the pharmaceutical industry or clinicians, 24-hour rhythms in physiology are a factor of potential influence on the pharmacokinetics and pharmacodynamics of drugs.

Molecular Physiology is a research group at the Leiden Institute of Chemistry dedicated to the design, synthesis and application of chemical tools to study important biological and biomedical questions. The group is headed by Prof. Dr. Mario van der Stelt and includes the research lines of Assistant…

In this research group, headed by Laura Heitman, novel receptor concepts in drug discovery are studied, aiming to increase the effectivity of medicines. Many drugs act via so-called G protein-coupled receptors (GPCRs) and therefore our research is mainly focused on understanding and improving drug-receptor…

The ambition of the Metabolomics and Analytics Centre led by Thomas Hankemeier is to develop innovative analytical strategies for metabolomics-driven health monitoring and systems biology studies. Understanding the intricate balance between health, disease and adaptation to challenges relies on the…

The Delivery of Biotherapeutics research group is led by Prof. Matthias Barz and focusses on the synthesis and characterization of polypept(o)ids and their application in nanomedicine to improve existing therapies or enable novel diagnostic or therapeutic approaches.

This is an Erasmus+ International Credit Mobility project of Leiden University Medical Center with the University of Havana.

One of the most crucial aspects of our behaviour is our motivation to explore novel environments and interact with new people. This became painfully clear during the COVID-19 lockdowns, when many people suffered from lack of new experiences and real-life social interactions. The relevance of novelty…

This specialisation focuses on two important trends in health care: early diagnosis and developing the most targeted patient-specific treatment possible with the shortest possible recovery time and minimal side effects.

The CIGR brings together a diverse range of unique expertise in genome research rooted in biology, chemistry and physics. Members of the CIGR investigate genome folding and genome transactions. An important aspect is direct as well as long term relevance for medicine.

In this thesis, single-cell approaches were applied to characterize the impact of aging on the immunological B cell landscape in different models of atherosclerotic cardiovascular disease, with the goal to identify and study new B cell-associated biomarkers and therapeutic targets to halt atherosclerosis…

The research master’s specialisation Clinical and Health Psychology prepares you for a PhD trajectory.

Despite substantial progress in understanding tuberculosis (TB), the eradication of the TB epidemic is still far from reach.

Apps that can precisely identify shards, coins or heel bones: archaeology has embraced artificial intelligence. Alex Brandsen is working on a search engine that scans vast quantities of text from an archaeological viewpoint.