Promotor: Prof.dr. H.P. Spaink, Co-promotor: Prof.dr. A.H. Meijer

Promotores: J.N. Kok, H.J. Hoogeboom

We developed the bitterling as a unique, well-studied model organism in the area of the evolutionary ecology of brood parasitism. The bitterling-mussel relationship, interspecific mussel host preference, and mussel gill structure are studied in detail, to help understand the developmental adaptation…

Epithelial-mesenchymal plasticity (EMP) and tumor cell migration play an important role in cancer progression, and an improved understanding of the mechanisms underlying these concepts is essential for developing new targeted approaches.

This thesis is devoted to an in-depth examination of the various effects of disorder in the cuprate high-temperature superconductors.

Mouse models are commonly used to assess the immunogenicity of therapeutic proteins and to investigate the immunological processes leading to antidrug antibodies. The aim of this work was to develop a transgenic (TG) Balb/c mouse model for evaluating the immunogenicity of recombinant human insulin (insulin)…

Pulsars were first discovered in 1967 and since then the population has grown and expanded over several wavelengths.

This thesis is a collection of experimental attempts to enhance photoluminescence of fluorescent molecules and quantum dots with single gold nanorods (GNRs) and relevant applications.

Engineering an efficient microbial enzymatic polyethylene degradation pathway via an innovative combination of biochemistry and computational biology tools for enzyme discovery and characterization.

Understanding how galaxies form, interact, and evolve comes largely from comparing theory predictions with observational data. Numerical simulations of galaxies provide the most accurate approach to testing the theory, as they follow the non-linear evolution of gas and dark matter in great detail and…

Design of a Linguistic System for Interstellar Communication Based on Logic

The plant hormone auxin plays a central role in the growth and development of plants. Auxin acts in a concentration dependent manner and polar cell-to-cell transport of this hormone determines its distribution in the tissues of plants. This polar auxin transport is mediated by several families of auxin…

Promotor: M.L. van Hecke, Co-Promotor: B.P. Tighe

This is an Erasmus+ International Credit Mobility project of Leiden University’s Faculty of Governance and Global Affairs with Fukushima University.

In 2025, GTGC co-organised with the City of The Hague and the Hague Humanity Hub a Just Peace Festival, a vibrant platform on the pressing global challenges of peace with justice. The festival involved a wide range of different activities, including dialogues, exhibitions, performances, film evenings,…

Streptomyces are bacteria abundant in soil that participate in diverse and complex interactions. These bacteria are the main producers of the antibiotics we currently use in the clinic.

Promotores: G.W. Canters, T.J. Aartsma

Promotor: G.F.A. Kersten, W. Jiskoot, Co-promotor: B. Metz

Antonia Lamers, PhD at ICLON, researched how to create a TNE teaching and learning environment that is in line with the expectations of the British programmes offered to students in Oman.

Over the last three decades, the discovery of exoplanets has revealed the boundless variety of worlds beyond our own Solar System⁠. Majority of planetary systems contain short-period planets that are larger than Earth but smaller than Neptune⁠.

Promotor: J.N. Kok, Co-promotor: F.J. Verbeek

Seminar

When you have finished your dissertation, it is time to prepare for the defence procedure.

Promotor: Prof.dr. G.R. de Snoo

PURPOSE: To monitor the biodistribution of IgG1 aggregates upon subcutaneous (SC) and intravenous (IV) administration in mice and measure their propensity to stimulate an early immune response.

Electrons in a crystal lattice have properties that may differ from those of a free electron in vacuum.

Leiden University is an international, broad-based university. We distinguish five core domains for our research and teaching activities.

Salicylic acid (SA) is a plant hormone, which is involved in the defense responses to pathogens and to abiotic stress, and in the regulation of plant growth and development.

In the current global context, there is a pressing need to address sustainable energy supplies to safeguard our Planet and its ecosystems. The choices made by human society have a significant impact on genetic evolution and climate.

Faculty of Archaeology, University of Leiden

Stars and planets form within cold, dense clouds of gas and dust drifting through interstellar space. Although dust makes up only a small fraction of this material, it plays a key role in shaping the chemical evolution of these environments.

Promotor: M. de Jong, Co-Promotor: Samtleben

Leiden psychologist Wilco van Dijk and communication scientist Jaap Ouwerkerk of VU University Amsterdam published a book about the emotion Schadenfreude. The authors describe what the emotion Schadenfreude really is, when people experience the emotion, and what role it plays in social relations.

Career and apply for jobs

Plants and soils from natural ecosystems harbor great diversity of soil microorganisms, which could potentially contribute to the sustainability of horticulture. The knowledge about using wild plant species and soil from natural ecosystem to improve the crop health will advance the application of ecological…

Nietzsche's most famous and infamous book Thus Spoke Zarathustra is perhaps the most read, but probably also the least understood, book in Nietzsche's oeuvre. Nietzsche considered it his highlight. He called it a symphony, a holy book, a fifth gospel and even the greatest gift ever given to humanity.…

Promotores: C. J. ten Cate; M. A. Ainslie. Co-promotor: W. Slabbekoorn

What are the functions of the endocannabinoid system?

A comparative study in the History of Modern Philosophy focused on the recourse to physiology on the part of two key figures, Spinoza and Nietzsche.

In the research programme Microbial Sciences we perform state-of-the-art research in the field of biotechnology and microbial sciences.

The current resurgence of whooping cough is alarming, and improved pertussis vaccines are thought to offer a solution. Outer membrane vesicle vaccines (omvPV) are potential vaccine candidates, but omvPV-induced humoral responses have not yet been characterized in detail.

The aim of this thesis is to expedite and ensure the systematic accuracy of clearance scaling from adults to paediatric patients, with a special focus on drugs undergoing hepatic metabolism.

Predictive maintenance (PdM) is a maintenance policy that uses the past, current, and prognosticated health condition of an asset to predict when timely maintenance should occur.

In human cells, a meter-long DNA is condensed inside a micrometer-sized cell nucleus. Simultaneously, the genetic code must remain accessible for its replication and transcription to functional proteins.

Promotor: P.G.L. Klinkhamer, Co-Promotores: K. Vrieling, P.P.J. Mulder

The Institute of Public Law comprises all areas of public law, with the exception of criminal law, and including labour law.

Focus in skin research

Microscopic insight on lipid-based nanomedicine in vivo remains limited to the perception of the knowledge that could be obtained: if we interpret only what we see, then we only believe to know. Although believing to know encapsulates an undefined amount of uncertainty in the exploration of lipid-based…

Business Process Model and Notation (BPMN) has become the standard for business processes diagrams.