Promotor: A.W. van der Vaart

This dissertation focuses on developing new mathematical and statistical methods to properly represent time-varying covariates and model them within the context of time-to-event analysis.

Methodology and Statistics focuses on the development, evaluation and application of statistical models for the analysis of psychological research data.

Are you thinking about studying Methodology and Statistics in Psychology? Learn more and watch the videos.

The programme group Research Methods and Statistics develops and teaches the large majority of methodological courses in all phases of the program Education and Child Studies.

In the specialisation Methodology and Statistics, part of the Master in Psychology, you will focus on in-depth study of statistical theory and research methodology as well as on the acquisition of data analysis skills.

The programme group Research Methods and Statistics offers methodological support in many projects in the field of education and child studies.

Next April, Leiden will host the seventh annual international Survival Analysis for Junior Researchers conference (SAfJR2018). This three-day event is aimed at career-young statisticians with an interest in the application and development of time-to-event analysis and related topics. The conference…

The programme group Research Methods and Statistics offers support to researchers from a variety of research projects within Education and Child Studies.

The research programme Statistical Science is concerned with the analysis and interpretation of masses of data, the quantification of uncertainty using probability models, and the development and benchmarking of algorithms and methods with these aims.

Can the (industrial) herbal extraction process be mathematically described and can this model be used to optimize the extraction in terms of quality and economical parameters?

Promotor: P.D. Grünwald

Peter Grunwald

The Mathematical Institute is responsible for the research and education in mathematics and statistics at Leiden University.

Novel methods for understanding key aspects that are essential to the future of Bayesian inference for high- or infinite-dimensional models and data.

Systems pharmacology aims to apply techniques from systems biology to pharmacological models.

In this project, we aim to develop mathematical models to mechanistically and quantitatively predict the dynamics of cellular stress pathway activation and its relation with toxic effects when cells are exposed to various toxicants.

The master’s programme Mathematics at Leiden University focuses on analysis, probability and statistics, number theory and (arithmetic) geometry. It offers five specialisations ranging from Applied Mathematics to Mathematics and Business Studies.

The master’s programme Statistics & Data Science provides students with a thorough introduction to the general philosophy and methodology of statistical modelling and data analysis. The programme has two specialisations: Data Science and Statistical Science.

Netherlands Statistics (CBS), Leiden University and the University of Amsterdam have started a collaboration in the form of a research project titled 'Enriching official economic statistics using data-driven modelling techniques'.

The Leiden University Center for Statistical Science unites the statisticians teaching and researching at Leiden University.

Mathematics forms the basis of many innovations in technology, the service industry and science, such as data analysis and coding, artificial intelligence, weather or climate change modelling or understanding molecular processes. The researchers from the Mathematical Institute (MI) are constantly developing…

PhD candidates carry out a programme of independent research, leading to a PhD thesis in typically 4 years.

A novel mathematical model describes spatial-temporal drug distribution within one or more brain units, which are cubic representations of a piece of brain tissue with brain capillaries at the edges.

The group Statistical Science is responsible for research and teaching in statistics and data science.

Immunotherapies for cancer are an emerging class of therapeutic strategies which aim to treat cancer via augmentation of the immune system.

Epithelial-mesenchymal plasticity (EMP) and tumor cell migration play an important role in cancer progression, and an improved understanding of the mechanisms underlying these concepts is essential for developing new targeted approaches.

The aim of this project is to determine in which cases uncertainty statements resulting from a Bayesian statistical analysis can be trusted.

The master's specialisation Applied Mathematics at Leiden University focuses on both computational and fundamental aspects of analysis and probability. It’s also an ideal basis for a PhD degree. Applied Mathematics is an excellent choice if you have the aspiration to pursue a PhD degree

Are you thinking about studying Mathematics? Learn more and watch the introduction video.

The availability of complete plant genome sequences together with the ever increasing amount of data on the molecular, cellular and physiological mechanisms of plant development require mathematical and computational models to obtain a complete overview of and generate new insights into the quantitative…

PhD candidates carry out a programme of independent research, leading to a PhD thesis in typically 4 years.

Perform cutting-edge research in the area of the STAR mathematics cluster.

The Graduate School of Social and Behavioural Sciences in collaboration with the Department of Methodology and Statistics and researchers in the field of Methodology and/or Statistics of the other Institutes provides training courses for PhD candidates and other researchers.

Systems with local constraints is a new finding in recent researches on complex systems. The heterogeneous spatial interactions and the temporal dependencies among those numerous units make it difficult to describe by traditional statistical physics.

Cellular stress response pathways are activated upon exposure to chemicals and help organisms deal with various molecular dangers (e.g. oxidative stress). When these pathways become hyper-activated an adverse response takes place and cells die, which may lead to organism-level toxicity such as drug-induced…

Promotores: J.C. van Houwelingen, S.A. van de Geer

As a Mathematics student, you will learn to solve complex problems in creative ways using logical thinking and mathematical structures. A Mathematics degree will open many doors for you in society.

This research team is concerned with the measurement and modelling of behaviour, cognition, and unobserved traits (e.g., latent variables, missing data). Central aims include the distillation of a complex set of features into lower-dimensional representations (e.g., factor analysis, IRT), determining…

Despite being the object of intense study, embryonic development has been difficult to model due to a number of reasons. First, complex tissues can be comprised of many cell types, of which we probably only know a subset.

How does the extracellular matrix coordinate endothelial cell behavior during angiogenesis, and how do metabolic waste-products and matrix-degrading enzymes produced by the tumour modify the extracellular matrix so as the change the cellular coordination?