Promotor: F.H.J. Redig, Co-Promotor: W.T.F. den Hollander

Existing work in probabilistic language modeling can be mostly divided into two categories:

Description of Biotic ligand models: making an inventory of available models & assessment of the variability of the predicted HC5 using the BLMs in different Dutch water types (2005 - 2007)

The Mathematical Institute offers a bachelor programme in Mathematics and master programmes in Mathematics and in Statistical Science. The institute also teaches many mathematics and statistics courses in other academic programmes of the university. About 65 PhD students work on a thesis in a small…

The parabolic Anderson model (PAM), which is the Cauchy problem for the heat equation with random potential. The PAM is a mathematical model that describes how mass (i.e. matter or energy) flows in a medium in the presence of a field of sources and sinks.

Are predictive archaeological maps a reliable tool to play an important role in the spatial planning? One of the goals of this project was to develop best practices for the production and application of the models.

The Mathematics master’s programme will guarantee a thorough theoretical basis and will make sure you are ready to work in a multidisciplinary environment. Your mathematical degree will give you the right tools to operate successfully on the international market.

The Mathematics and SCS master specialisation gives you the opportunity to combine Mathematics research with different aspects of science communication.

Do you recall all those drugs that were hastily proposed as potential treatments for COVID-19? In the event of a future pandemic, the goal is to offer an effective treatment more quickly and efficiently. To achieve this, a team led by Coen van Hasselt is developing a platform that can speed up the process…

The two-year research programme Applied Mathematics offers courses at an advanced level. There is a large degree of freedom in choosing one’s own topics. Some of the courses are given at national level, in the Dutch Mastermath programme. The programme concludes with the preparation of a master’s the…

Real-life processes are characterized by dynamics involving time. Examples are walking, sleeping, disease progress in medical treatment, and events in a workflow.

During the coronavirus pandemic, scientists were in a hurry to find drugs that would help fight the disease. To combine the research that was being carried out around the world, PhD candidate Judith ter Schure developed a new statistical method: ALL-IN meta-analysis. This helps determine sooner whether…

Can we establish a new quality control system for herbal medicines that is based on bioactivity rather than a few abundant chemicals?

Promotor: Prof.dr. E. Deprettere

In 2016, Dutch University Medical Centres (UMCs) developed the self-evaluation tool based on the PhD Competence Model. Our partners at Utrecht University are making a digital version of the tool available free of charge for our PhD candidates at Leiden University, including for candidates who are not…

The aim of this thesis was to develop novel treatment strategies for different types of eye melanoma utilizing zebrafish models. We first establish orthotopic and ectopic xenograft models for uveal and conjunctival melanoma by engraftment of the immortalized cells derived from these tumors into zebrafish…

Main challenges in skin vaccination are overcoming the stratum corneum (SC) barrier and targeting the antigen presenting cells (APC) in the epidermis and the dermis.

Promotores: Prof.dr. P.C.W. Hogendoorn & Prof.dr. H.P. Spaink, Co-promotor: Dr. B.E. Snaar-Jagalska

Arts and leisure, Arts and leisure

The master's specialisation Data Science: Computer Science at Leiden University provides students thorough knowledge and understanding of statistical and computational aspects of data analysis, including their application in databases, advances in data mining, networks, pattern recognition, and deep…

Statistics & Data Science is highly multidisciplinary. Within the programme we offer you a unique combination of knowledge and expertise through close collaboration.

Death in all types of melanomas is generally caused by metastasis. Uveal melanoma (UM) is the most common intraocular melanoma, there are currently no (patient-derived) animal models that faithfully recapitulate metastatic dissemination of UM.

Industrial manufacturing processes, such as the production of steel or the stamping of car body parts, are complex semi-batch processes with many process steps, machine parameters and quality indicators.

The Algebra, Geometry and Number Theory specialisation gives you profound knowledge of pure mathematics. The focus is on both fundamental mathematics and on applications in other sciences, society and industry. During your master’s you will be part of one of the multidisciplinary research teams at the…

The Mathematics and Education master specialisation gives you the opportunity to combine Mathematics research with an excellent education in becoming a Mathematics teacher.

Italian nurse Daniela Poggiali was arrested and convicted of murdering two hospital patients in 2014. Her case attracted the attention of Leiden statistician Richard Gill. After his investigation, together with an Italian colleague, Poggiali was acquitted last autumn. Together with fellow statisticians,…

Prof. dr. Aad van der Vaart has been appointed as Scientific Director of the Mathematical Institute of Leiden University on Tuesday 15 September 2015. He succeeds prof. dr. Peter Stevenhagen who has been a dedicated Scientific Director of the Mathematical Institute as from 2007.

Clinical development of drugs for central nervous system (CNS) disorders has been particularly challenging and still suffers from high attrition rates.

The molecular mechanisms that instigate a healthy cell to become malignant are fueled by (epi)genetic alterations in so-called driver genes.

The central inquiry of this thesis revolves around how ontology can adequately accommodate the existence of necessary physical relations. Initially, the thesis demonstrates the imperative acknowledgment of necessary physical relations by showcasing the failure of Neo-Humean theories.

The Mathematical Institute is one of the eight institutes of the Faculty of Science. The institute operates as a single unit defined by the activities of its members.

The main methodological aspects of the use of stepwise LCA estimators under different circumstances.

Promotor: Prof.dr. F.S. de Boer, Co-promotor: D. Clarke

Promotor: Prof.dr. B. van de Water, Co-promotores: L.T.M. van der Ven, A.S. Kienhuis

In a recent TEDx Flanders event “Statistical Errors in Court”, Statistical Scientist Richard Gill speaks about the case of Lucia de Berk, a nurse found guilty of several murders based largely on statistics.

Making a dynamic substance stock model in order to conduct scenario analyses and make forecasts.

You may contact LUXs through any of its members or secretariats of its participating institutes. You may also reach the steering group through its chair or secretariat.

Promotor: Prof.dr. B. van de Water, Co-promotor: L.S. Price

Promotor: Prof.dr. J.N. Kok, Co-promotor: F.J. Verbeek

Many organisations have a biased workforce, even though diversity has so many advantages. Australian and Dutch researchers, including Leiden psychologist Romy van der Lee, have developed a solution based on a mathematical model. They published their findings in PLoS One on 28 July.

ASLU 14

In this thesis, we extend the concept of null models as canonical ensembles of multi-graphs with given constraints and present new metrics able to characterize real-world layered systems based on their correlation patterns.

From surface science towards industrial practice using high-pressure scanning tunneling microscopy.

Promotor: Prof.dr. W.J.G.M. Peijnenburg, Co-promotor: Dr. ing. M.G. Vijver

Combine training in Mathematics research with different aspects of business studies. Learn to build bridges between science and business.

In this research project child language phonology is studied from the perspective of a psycholinguistic speech-production model and this model is in turn studied from the perspective of developmental phonology.