Mathematician Stéphanie van der Pas, winner of the C.J. Kok Jury Award for her PhD thesis in 2017, divides her time between research and education, and between pure mathematics and practical application.

PhD defence

Chapter 1,contains the numerical verification of the Birch and Swinnerton-Dyer conjecture for hundreds of Jacobians of hyperelliptic curves of genus 2, 3, 4 and 5.

The two-year Master in Statistics & Data Science consists of 120 European Credit Transfer System (EC) points. It consists of a core set of mandatory courses, electives and a Master's Thesis Project.

Science, Institute of Biology Leiden (IBL)

Promotor: Prof.dr. J.N. Kok

Promotor: Prof. dr. A.G.G.M. Tielens

How might we include circularity into the models often used in IPCC reporting (in technical language, how can IAMs, dMFA models and CGE models be integrated?) What are possible futures for global resource use and what are the consequences for greenhouse gas emissions in these scenarios?

It is a common technique in global optimization with expensive black-box functions to learn a surrogate-model of the response function from past evaluations and use it to decide on the location of future evaluations.

The Minor in Teaching was introduced in 2009 as a new initiative to introduce and prepare bachelor students for teaching. Student numbers are low, however, especially of mathematics and science students.

Source: J Cheminform, Volume 7, Issue 1 (2015)

The objective of this project is the development of a new psychometric model, called the Generalized Squared Distance Logistic Model (GSDLM). This model is an evolution of older psychometric approaches (such as PARELLA, GHCM, and GGUM) and the Gaussian Ordination Models (GOMs) used in environmental…

Business Process Model and Notation (BPMN) has become the standard for business processes diagrams.

Promotor: Prof.dr. F. den Hollander

This September a new Masters Track

Following their application to system biological models, control theory techniques have further potential to aid in the understanding and application of quantitative systems pharmacology models.

How can zebrafish models be used to gain a better understanding of host-pathogen interaction mechanisms and to screen new drugs for infectious disease treatment?

In surface science there is great effort to move from studying simple, flat model surfaces in vacuum to investigating more complex model catalysts in gas environments (in situ). This thesis gives three examples of such studies using microscopy and spectroscopy.

A main goal of MSBB research is to address the major bottle-necks in combatting viral diseases: the lack of experimental models that are representative of human pathology and are cost effective and versatile. Viral diseases such as those that cause viral hemorrhagic syndromes or severe acute respiratory…

Describe and identify what dosimetry parameters are of importance to interpret dose-response relationships (eg., mortality, sub-lethal, growth or reproduction inhabitation, DNA damage and reactive oxygen species, etc. ) for metal-based nanoparticles? How to develop quantitative models that enable to…

PhD student Robbin Bastiaansen applies mathematics to get insight in practical problems. By comparing mathematical models with developments in existing ecosystems, he hopes to demystify the process of desertification. His research has been published in Proceedings of the National Academy of Sciences…

An integrated approach for the simultaneous prediction of polypharmacology and binding affinity/potency of small molecules.

Sepsis is a life-threatening condition caused by a dysregulated host response to infection, it is associated with significant morbidity, mortality, and with a high financial burden on global healthcare systems. Bacterial infections are the primary cause of sepsis, but the growing prevalence of antimicrobial…

In this research project Rohana analyzes and reflects on taqsīm recordings by two leading figures of ‘ūd playing who were pillars of modern Arabic music, namely the Egyptians Muḥammad al-Qaṣabjī (1898-1964) and Riyāḍ al-Sunbāṭī (1906-1981).

Appropriate animal models for intradermal vaccine delivery are scarce. Given the high similarity of their skin anatomy to that of humans, minipigs may be a suitable model for dermal vaccine delivery.

Promotores: Arjen Doelman, Jens Rademacher, Max Rietkerk

A research goal for ABS is to develop miniaturized platforms for research in (stem)cell, in-vitro systems and application in clinical and preventive research. Combined with the high throughput, this development will make it possible to study the dynamics of pathogenesis in human and cellular models…

Mathematical biologists from Leiden have developed a model that helps to explain how the spine and vertebrae, among other things, form during embryonic development. The same process, the other way around, plays a key role in cancer metastasis. Publication in iScience.

To limit the effects of climate change, global average temperature since pre-industrial measurements are to be kept well below 2 °C preferably even at 1.5 °C.

Contact details secretariat section Methodology & Statistics.

PBDL favors multidisciplinary research. Depending on the problems under investigation, PBDL establishes collaborations between experts from for example molecular genetics, molecular and electro cell physiology, biochemistry, organic chemistry, analytical mathematics, mathematical statistics and computational…

This dissertation addresses the different use of the same philosophical model: immanent teleology. In this work Aristotle, the founder of the study of final causes, is put in relation with the modern French evolutionary thinker Henri Bergson, the philosopher of time. The dissertation tackles the two…

The growing demand of energy indicates that global energy resources in the form of fossil fuels will not be sufficient in the future. In order to solve potential future energy problems development of a sustainable hydrogen economy is highly desirable.

Which traits did change due to the invasion process of plants and how do these traits contribute to the invasiveness of such species. What is the role of carbohydrate accumulation? What is the function of carbohydrate accumulation in plants? Is genetic variation depleted in invasive species under se…

Combining geometry and number theory. That is what Dr Jan Vonk of the Institute of Mathematics receives a Vidi grant for today. ‘By fusing these two disciplines we may be able to solve a century-old mathematical problem.’

The project Deconstructing Stability aims to improve reconstructions of late prehistoric landscapes and predictive models for the purpose of archaeological heritage management.

Lecture

Lecture, Lunch included

In this thesis we study quantum transport phenomena on the nanometer scale, in two classes of materials: topological insulators with induced superconductivity and graphene superlattices.

You gain a strong foundation in computer science, combined with knowledge of machine learning, cognitive science, human-robot interaction. You will learn to develop and program systems based on knowledge of the human brain.

Marta Fiocco, associate professor at the Mathematical Institute of Leiden University, has signed an agreement with the UWV (the administrative authority that implements employee insurances and provides labour market and data services) to work with their data in the research project

Floske Spieksma will give her inaugural lecture as Professor of Mathematics of Operations Research on 1 September. A discussion about mathematical models, Venezuela, trembling knees, being the only woman, casinos, intuition and above all loving your job.

The programme group Research Methods and Statistics is part of the Institute of Education and Child Studies. This group is located in the Faculty of Social and Behavioural Sciences of Leiden University near Central Station.

Promotor: Prof.dr. B.R. Katzy, Co-promotor: R. Ortt

Promotor: Prof.dr. J.N. Kok, Co-promotor: Dr. A.J. Knobbe