283 search results for “drug discovery” in the Staff website
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Modified caffeine molecules help medical research move forward
Before researchers can develop targeted drugs, they need to know exactly how a disease works. Biochemist Bert Beerkens created molecules that allow them to find out. He used caffeine as the basis for new molecules that enable research into certain receptor proteins on cells.
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Antibiotic resistance: an economic problem universities could help to solve
Antibiotic resistance is an economic problem. Pharmaceutical companies cannot earn much from antibiotic research, so they do not invest in it. This makes it important that universities do so, says Ned Buijs.
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NWO-XS grants for two innovative research projects
Two Leiden Science researchers received an NWO-XS grant for their research. Both projects are highly promising, but also high-risk. Macrophages that trap bacteria and data storage made from 2D materials convinced the board of their potential.
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Gerard van Westen wins KNCV Gold Medal
Gerard van Westen has received the KNCV Gold Medal, the most important Dutch award for chemists under 40. 'It's a huge honour,' says the professor of AI and medicinal chemistry. 'I am now part of the group of people I was always impressed by.'
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Multiple KHMW awards for science students
As many as seven first-year students from the Faculty of Science were honoured as young talents. In addition, the Royal Holland Society of Sciences and Humanities (KHMW) also lauded three master's students and an astronomy project during a vibrant ceremony on 28 November. Professor of Science Communication…
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The career choices of cells
How does an embryonic stem cell decide if it becomes a heart cell or a kidney cell? That’s the question computational biologist Maria Mircea studied for her PhD research. She looked at the inside of individual cells to analyse how they change. This is what she discovered.
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Reliable research with virtual patients
The right medicine in the right dosage for every patient, that is something medical science aspires. 'Personalised medicine' is the term for that. But it does require a lot of research with patient data and that can be hard to get due to privacy legislation. Researchers Laura Zwep and Coen van Hasselt…
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In 450 days... 450 years of Leiden University
In exactly 450 days’ time, on 8 February 2025, it is the university’s 450th anniversary. We are obviously going to celebrate this with our students, staff and friends. Do you have any ideas for this celebration?
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In memoriam Jan Zaanen 1957-2024: The universe in a speck of rusting copper
This Thursday, January 18th 2024, our esteemed colleague Jan Zaanen passed away. Jan was one of our star scientists, larger than life, with an unabashed, boisterous drive for the best of physics at the Institute Lorentz, at the Leiden Institute of Physics and in the full international scientific community.…
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LACDR-Bruker Bio-AFM workshop: connecting disciplines through force spectroscopy
On the 6th and 7th of September 2023, the Leiden Academic Centre for Drug Research (LACDR) organized the Leiden Bio-AFM workshop in cooperation with Bruker Nano GmbH (Germany) and Bruker Nederland BV. The organization of this event was led by the Medical Systems Biophysics and Bioengineering group (Alireza…
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Rawi Ramautar new Programme Director of Bio-Pharmaceutical Sciences bachelor’s program
Rawi Ramautar will be the new Programme Director of the bachelor of Bio-Pharmaceutical Sciences starting September 1. The appointment is for four years. Ramautar succeeds Erik Danen, who has held the position since 2019.
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Suzanne van der Pluijm to be Science Faculty’s new Executive Director
Suzanne van der Pluijm will be appointed Executive Director and Member of the Board of the Faculty of Science with effect from 1 June 2022. She succeeds Ed van den Berg, who has held this position on an interim basis since 1 September 2021 .
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Templeton Grant Drukker News
In a project funded by the John Templeton Foundation to the group of Micha Drukker, scientists will produce stem cells from short and long living understudied species to model cellular and organismal lifespan.
- IBL Symposium 2022
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Exhibition on Anton de Kom’s second life, which began in Leiden
Few people would associate the name Anton de Kom with Leiden. Yet the Surinamese freedom fighter is the subject of an exhibition at Museum De Lakenhal.
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Leiden Classics: Einstein & Friends
Museum Boerhaave commemorated the hundredth anniversary of Einstein’s Theory of General Relativity with the exhibition ‘Einstein & Friends’. The exhibition shined light on the famous physicist’s Dutch friends and his love for Leiden. A review featuring seven images can be found below.
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National Meat Free Week: the main reasons to switch to a plant-based diet
National Meat Free Week (Nationale Week Zonder Vlees, 7–13 March) is an initiative to reduce meat consumption. Assistant professor Paul Behrens is studying what impact a change in our food consumption would have on the world. What, according to him, are the main reasons to switch to a (mainly) plant-based…
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Literary Leiden
Quietly read a book in our new reading nook, listen to interesting and bizarre stories set in early twentieth-century Leiden, walk past literary locations in Leiden and watch the best film adapted from a Leiden novel as decided on by you. April is Literary Leiden month! A month in which we pay special…
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Wat is er te doen op de Leidse Museumnacht?
Op zaterdag 3 juni vindt de Museumnacht Leiden plaats. Ook dit jaar zijn Leidse wetenschappers en studenten onderdeel van de programmering.
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Surprising molecule helps detect protoplanets
A team of scientists, including Leiden Astronomer Alice Booth, has discovered silicon monosulfide molecules in the dust disk around a young star. Such molecules indicate planet formation. The team made the discovery using the ALMA telescopes. This method provides an alternative when direct observation…
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Prize for school research project on butterfly wings
Why are morpho butterflies blue? That is what high school students Frederique Kerstens and Koen van Griensven investigated in their high school profile paper at the Leiden Institute for Research in Physics. In doing so, they won the KHMW Profielwerkstukprijs 2023. ‘We didn't expect it, but are of course…
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The search for a ‘quantum advantage’
Proving a quantum computer to be quicker than a normal one is one step closer. After a breakthrough in speeding up classical algorithms, researchers Vedran Dunjko and Casper Gyurik showed that only one quantum algorithm could beat its classical counterpart. They discuss their discovery in Quanta Mag…
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New! Latest acquisitions UBL, sorted by field on one page
Education, ICT, Library, Research
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Three Leiden researchers receive ERC Synergy Grant
Leiden researchers Arjen Doelman, Tom Huizinga and Manfred Wuhrer have been awarded ERC Synergy Grants worth millions of euros for their research on preventing tipping points being reached in ecosystems and helping eradicate rheumatism.
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'Working with PhD candidates gives me energy'
Erik Danen is the new Dean of the Graduate School from 1 January. He is a professor at the Leiden Academic Centre for Drug Research and conducts research into cancer drugs. Danen is really looking forward to it: ‘PhD candidates are a special group: that's what I like to dedicate myself to.’
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‘I am curious and full of passion for understanding molecular chemistry’
Since May, Assistant professor BioTherapeutics Lu Su works in our faculty. Although she is still young, she already worked in many different fields and co-operated on two publications in big scientific journals. How did she become so successful and what motivates her to keep researching the possibilities…
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Lowlands as lab: virtual trips in the name of science
While tens of thousands of visitors dance to deafening music, a team of Leiden psychologists are trying to collect data for their research at Lowlands. How do festivalgoers experience a virtual trip? And what role do factors such as too little sleep and whether they have experience with psychedelics…
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Improving safety assessment of nanoparticles
How safe are the nanoparticles in transparent sunscreen, anti-odour socks and bacteria-resistant plasters? Although microbes are present on all organisms, the tools that estimate the safety of nanomaterials still hardly take them into account. Bregje Brinkmann explored the role of these microbes during…
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Heineken Young Scientists Award for three Leiden researchers
Three of the four Heineken Young Scientists Awards for 2022 have gone to researchers from Leiden: chronobiologist Laura Kervezee, physicist Jordi Tura i Brugués and health psychologist Liesbeth van Vliet.
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Master's student Nicole ter Laak wins KNMP Studentenprijs 2023
Biopharmaceutical sciences master's student Nicole ter Laak has won the KNMP Studentenprijs 2023. She wins the prize for her research project on dosing guidelines of antibiotics in newborn babies with a very low birth weight for gestational age.
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Rubicon grant for four Leiden researchers
Four promising young researchers from Leiden University have received a Rubicon grant from the Dutch Research Council (NWO). This grant will enable them to gain valuable research experience at top universities abroad.
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A plan of the faculty: 'In France, it would have been a plan of the boss'
The moment has finally arrived: after months of hard work, the strategic plan is finished. It was an interesting period, thinks core group member Sylvestre Bonnet. 'How we finally arrived at this strategic plan was very different from what I had thought beforehand.'
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Artificial microswimmers work together like bacteria
Microscopic swimmers such as bacteria do not always swim alone. There are advantages to exchanging information and cooperating. Stefania Ketzetzi and colleagues now show in Nature Communications that human-made microswimmers, too, can cooperate.
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ERC grant to further investigate next-generation antibiotics with reduced toxicity
The European Research Council (ERC) has awarded Nathaniel Martin a Proof of Concept (PoC) grant. With it, his group aims to make a dangerous but potent antibiotic less toxic. He receives €150.000.
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Exhibition shows the ‘beauty and power’ of mathematics
In the ‘Imaginary’ exhibition, its curators show how society is made up of mathematics. From algorithms that save lives to ones that generate art. The exhibition is from 2 June to 25 July at Oude UB in Leiden.
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The hunt for nanoplastics is on
How do you count the nanoplastics in your body? Leiden researchers published a method in Nature Protocols today that should make this easier. Important for both environmental and medicine research.
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The LeiCNS-PK3.0 model development and applications: Healthy-to- diseased CNS pharmacokinetic translation
PhD defence
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From research in space to director on earth
After ten years and one day, Leiden Observatory has a new director. As of 1 September, Ignas Snellen will set the course for the astronomical institute. In this interview, you will get to know Ignas. Or at least a little. That is why we gave him five dilemmas and asked the people around him who he really…
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Innovating Cell Pharmacy with stem cells
Lecture
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BEAT-COVID team discovers sugar-coated antibodies that predict disease progression
At the start of the COVID-19 pandemic, researchers from 15 departments at Leiden University Medical Center (LUMC) realised they could do more for patients if they joined forces. This is how the BEAT-COVID group has been able to rapidly gain knowledge about COVID-19, the role of the immune system and…
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New research project makes the internet even better
How is it that the internet works so well, with billions of users sending millions of gigabytes all together every day? That's because the foundation of the internet is solidly set up. Yet sometimes there are problems on the internet. For example, when certain systems misbehave and disrupt the routing…
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Student well-being in the spotlight at the EUniWell symposium
‘There’s so much knowledge, research and experience in the field of student well-being. Let’s put this topic on the agenda, work together to promote it, and learn from each other.’ This was the message of the two-day virtual symposium on Good Practices for Student Well-Being.
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Tackling climate change with the ground beneath our feet
Soil ecologist Emilia Hannula has been awarded a Vidi grant by NWO to examine how soil could become a promising ally in combating climate change and improving biodiversity. ‘Soil creatures might be invisible’, she says, ‘but they play a huge role in creating a healthy environment.’
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Astronomers see birth cluster of galaxies in early universe
An international team of astronomers has discovered a large reservoir of hot gas in the cluster-in-formation around the Spiderweb Galaxy. Based partly on that hot gas, the astronomers predict that the cluster-in-formation will grow into one of the largest objects in the universe. A step closer to discovering…
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Inkomen en afkomst zijn risicofactoren bij kans op hart- en vaatziekten
Nederlanders met lage inkomens lopen tot 1,5 keer meer risico op het krijgen van een hartaanval of beroerte dan rijkere landgenoten. Bij Surinaamse Hindoestanen is dit risico 1,9 keer hoger. Dat blijkt uit onderzoek van het LUMC en het HagaZiekenhuis. Nederlandse artsen kijken tot nu toe niet naar deze…
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Even a duck can parrot
That a parrot can copycat sounds is nothing new. But vocal learning is not common in animals. Researcher Carel ten Cate of the Institute of Biology Leiden (IBL) of Leiden University has now discovered a duck species that can imitate sounds. ‘It started with an obscure reference about an Australian musk…
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New method to find Majorana’s tested for the first time
Jianfeng Ge and Milan Allen of Leiden University look for majorana quasiparticles using shot noise measurements
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Research and current affairs: 2022 in six stories
Life returned to something resembling normal after Covid but other crises soon took its place. These great challenges are also being felt at the University and our researchers are working on solutions. The nitrogen crisis, problems with young people’s services and an increasingly urgent climate crisis:…
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Corrugated plastic unveils a new design principle for programmable materials
Martin van Hecke en Anne Meeussen publiceren in het tijdschrift Nature over mechanische metamaterialen. Ze hebben een nieuwe klasse multistabiele materialen ontdekt. Dit is gebaseerd op ribbeltjes plastic.
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Exploration of the endocannabinoid system using metabolomics
PhD defence