49 search results for “genes” in the Staff website
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live longer? Leiden physicist makes discovery in protective layer in genes
With the aid of physics and a minuscule magnet, researchers have discovered a new structure of telomeric DNA. Telomeres are sometimes seen as the key to living longer. They protect genes from damage but get a bit shorter each time a cell divides. If they become too short, the cell dies. The new discovery…
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First patient in the Netherlands successfully treated with stem cell gene therapy
Researchers from the Leiden University Medical Center (LUMC) have successfully used stem cell gene therapy to treat a baby with the severe congenital immune disorder SCID. An important milestone: it is the first time stem cell gene therapy of Dutch origin has been administered to a patient, and also…
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Caught in living cells: how bacteria regulate their genes to defend themselves
For the first time, it was shown in living cells how the bacterium E. coli regulates genes that help it survive in a new environment. Biochemist Fatema Zahra Rashid managed to do this using a technique she fine-tuned. Her research into changes in 3-dimensional chromosome structure offers clues for ways…
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Merijn de Bakker
Science
m.a.g.de.bakker@biology.leidenuniv.nl | +31 71 527 5043
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Guillermo Guerrero Egido
Science
g.guerrero.egido@biology.leidenuniv.nl | +31 71 527 4791
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Priyanka Chopra
Science
p.chopra@biology.leidenuniv.nl | +31 71 527 1886
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Manon de Visser
Science
m.c.de.visser@biology.leidenuniv.nl | +31 71 527 4882
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Remus Dame
Science
rtdame@chem.leidenuniv.nl | +31 71 527 5605
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Paul Hooykaas
Science
p.j.j.hooykaas@biology.leidenuniv.nl | +31 71 527 4933
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Salma Balazadeh
Science
s.balazadeh@biology.leidenuniv.nl | +31 71 527 4790
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Pingtao Ding
Science
p.ding@biology.leidenuniv.nl | +31 71 527 5306
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Chao Du
Science
c.du@biology.leidenuniv.nl | +31 71 527 4947
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Tom van der Wel
Science
t.van.der.wel@lic.leidenuniv.nl | +31 71 527 3527
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Felix Wittleben
Science
f.t.wittleben@liacs.leidenuniv.nl | +31 71 527 1718
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LUMC researchers: high levels of lipids in blood protect against allergies
People with relatively high levels of lipids in their blood are less likely to develop allergic conditions such as eczema and asthma. These lipids cause genes that play a key role in allergic reactions to be less active. Researchers from the Leiden University Medical Center (LUMC) have published an…
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Supergenes make bizarre traits possible
Within the same species of butterfly many different wing patterns can occur. How is this possible? According to researchers Ben Wielstra and Emma Berdan, of the Institute of Biology Leiden (IBL), the answer lies within supergenes. A supergene is a part of a chromosome that contains many strongly linked…
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analyst position in projects in animal stem cell models
Science, Leiden Academic Centre for Drug Research (LACDR)
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Revolutionizing plant protection strategies: Ding lab receives 2.4M grant to investigate plant immunity
Plant biologist Pingtao Ding, assistant professor at the Institute of Biology Leiden (IBL), has received a 2.4 million European grant from the European Research Council (ERC). This ERC Starting Grant for promising young researchers allows him to unravel the molecular mechanisms by which plants resist…
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‘Look beyond your own discipline’
Good research means looking beyond disciplinary boundaries, said Professor of Molecular and Cellular Biochemistry Remus Dame in his inaugural lecture on 10 May. Processes that take place on DNA shouldn’t only be researched in a test tube but also in living cells, for instance.
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Developing new therapies to fight muscle disease
Biophysicist Alireza Mashaghi and his collaborators are taking up the fight against muscular dystrophy: genetic disorders that cause muscle weakness. They want to inhibit the clumping of proteins that results in toxic aggregates. For this, the team receives 550,000 euros from Health Holland. The team…
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Wood formation further explored by NWO-XL grant
Leiden researchers, Professor Remko Offringa and co-applicants Salma Balazadeh and Frederic Lens received an NWO-XL grant (2.5 million euros). Together with researchers in Wageningen and Groningen, they will study the genetic and environmental drivers of woodiness. From plant to molecule, the groups…
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Sibel Bahtiri is one of the new Faces of Science: ‘I want to show how we’re finding alternatives to animal testing’
PhD candidate Sibel Bahtiri is one of the new Faces of Science. In videos and blogs, she will show what life is like as a young researcher.
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EIC Pathfinder Challenge grant for research into autoreactive B cells in cardiovascular disease
At the division of BioTherapeutics, Amanda Foks, Bram Slütter and Ilze Bot have obtained a €4 million research grant from the HORIZON 2022 EIC Pathfinder Challenge “Cardiogenomics”, entitled “B-specific: B-cell related gene and protein markers with prognostic and therapeutic value for CVD”.
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ERC Consolidator Grants for Leiden researchers
Five Leiden researchers have been awarded a Consolidator Grant by the European Research Council (ERC). This grant of up to two million euros will enable them to continue and expand their scientific research.
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LUMC signs international agreement on developing Advanced Therapy Medicinal Products
Skåne University Hospital, Lund University and Leiden University Medical Center will work together to expand their research, teaching and development relating to Advanced Therapy Medicinal Products. That is the essence of a Memorandum of Understanding signed at SciLifeLab near Stockholm on Wednesday…
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NWO grant of 350.000 for Wielstra lab
Ben Wielstra and his team have received a ENW-M-1 grant. This grant of 354.000 euros is awarded by NWO, and will enable the researchers of the Institute of Biology Leiden and Naturalis to continue their evolutionary newt research.
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The career choices of cells
How does an embryonic stem cell decide if it becomes a heart cell or a kidney cell? That’s the question computational biologist Maria Mircea studied for her PhD research. She looked at the inside of individual cells to analyse how they change. This is what she discovered.
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Vici grants for three Leiden researchers
Three Leiden researchers have been awarded a prestigious Vici grant, the Dutch Research Council (NWO) announced on Tuesday. Two of the researchers work at Leiden University and the third at the Leiden University Medical Center (LUMC).
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Paco Barona Gomez ready to work in Leiden: ‘Fundamental research creates opportunities’
Paco Barona Gomez is the newest associate professor at the Institute of Biology Leiden (IBL). The Mexican researcher is fascinated by the evolution of natural products: compounds made by microbes, but also plants and animals. ‘It’s like we investigate chemical dark matter.’
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Students build software for real customers
Students gain practical experience while clients receive a solution to their software needs: the student software company LUDev hits two birds with one stone. ‘Through LUDev, students learn what else is involved in software development besides programming.’ Interested? You can now submit new projects…
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700,000 euros for the fight against aggressive breast cancer
To inhibit proteins that contribute to the growth of aggressive cancer cells, that’s the plan of Professor Bob van de Water and his team. They will receive over 700,000 euros from the KWF Dutch Cancer Society for their research. Researcher Maaike Vreeswijk and pathologist Danielle Cohen are affiliated…
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Leiden biologists get awarded 730k NWO grant
Salma Balazadeh, Víctor Carrión, and Jos Raaijmakers, biologists at the Institute of Biology Leiden (IBL), have successfully applied for an NWO grant and got awarded 730.000 euros. The board of NWO Domain Applied and Engineering Sciences awarded funding for their project within the Open Technology Programme…
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Sebastian Pomplun joins Oncode Institute to accelerate breakthroughs in cancer research
Sebastian Pomplun manages to reach proteins with drugs even where this was thought impossible. That is why he and his research group have been allowed to join Oncode Institute. With nine others, he had been selected from 72 applicants to contribute to Oncode Institute's mission: to accelerate breakthroughs…
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ERC Starting Grants for five young Leiden researchers
Five researchers from Leiden University have been awarded a Starting Grant by the European Research Council (ERC). This grant of on average 1.5m euros enables researchers who show potential to start their own project, lead a research team and implement their best ideas.
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Four Leiden consortia awarded large NWO grants
No less than four Leiden research teams have been awarded a grant by NWO. On 27 July NWO honoured 21 applications in the Open Competition ENW-XL. NWO awards the grants to consortia in the exact and natural sciences who are doing unconnected fundamental research that is 'driven by curiosity'.
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Promising new technique to treat cancer receives NWO grant
Biological chemist Nathaniel Martin and his team received an NWO grant to examine how blocking a specific enzyme in our body, NNMT, could be helpful in the treatment of some cancers. Trials with mice have been promising, and together with the Netherlands Cancer Institute, Martin wants to take the next…
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Researchers tackle antibiotic-resistant bacteria
When a bacterium becomes more resistant to one antibiotic, it sometimes becomes more sensitive to another. To better understand this interaction, researchers from the Leiden Institute of Biology (IBL) and the Leiden Academic Center for Drug Research (LACDR) under supervision of Daniel Rozen and Coen…
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Veni grants for 16 Leiden researchers
Sixteen researchers at Leiden University are to receive a Veni grant from the Netherlands Organisation for Scientific Research (NWO). These awards offer promising young researchers the opportunity to further develop their own ideas over a period of three years.
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What makes us ill?
Genes predict whether you have a propensity for an illness but environmental factors often have the last word: nutrition, air pollution, lifestyle, stress. The exposome as both culprit and chance. Large-scale research is being carried out into this at Leiden. Thomas Hankemeier, Professor of Analytical…
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NWA grants for interdisciplinary consortia
Several consortia in which Leiden University is involved have been awarded Dutch Research Agenda funding. Leiden is the coordinator of five of these consortia. These five consortia will receive grants worth a total of almost 24 million euros. They relate to interdisciplinary projects that will bring…
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Students work on bacterium that makes sustainable plastic
A group of biology students are working on a solution to the world’s plastics problem by getting bacteria to make biodegradable plastic.
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How animals flirt with each other
How do animals choose their partners? The answer is simple: it’s all about quality. While humans tend to wear clothes that happen to be in fashion, animals do nothing without a reason. Behind beautiful plumage or a deafening roar is only one message: I am in great shape. The evolutionary courtship displays…
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Learning Unkown Intervention Targets in Structural Causal Models
Lecture
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Joint Lectures on Evolutionary Algorithms (JoLEA)
Lecture
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How Oncode-PACT is bringing new cancer medicines closer with 325 million in Growth Fund money
How can you ensure that more experimental drugs reach the finish line? At the moment, only one in twenty cancer drugs that are tested on humans makes it to the market. This is an enormous loss for patients and society. With a grant from the National Growth Fund, Oncode-PACT aims to efficiently select…
- IBL Symposium 2022
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SAILS Lunch Time Seminar
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Causal Discovery: Challenges and Opportunities
Lecture
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Joint Lectures on Evolutionary Algorithms (JoLEA)
Lecture