636 search results for “heart diseases” in the Staff website
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Inexhaustible source of human heart muscle cells allows strong reduction of animal testing
Researchers at the Leiden University Medical Centre (LUMC) have managed to culture human heart muscle cells on a massive scale. This is an exceptional achievement because it is very difficult to replicate heart muscle cells outside the body. Using a special technique, the researchers have now created…
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Atherosclerosis resembles an autoimmune disease. Marie Depuydt graduated on this topic, with honours
In addition to cholesterol and high blood pressure as risk factors for atherosclerosis, we may need to address our own immune system to prevent a heart attack or stroke. Marie Depuydt revealed which cells exactly reside in the atherosclerotic plaque that narrows an artery. The presence of a diverse…
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Preventing heart attacks by earlier detection of cardiovascular disease
In the Netherlands, 1.55 million people suffer from cardiovascular diseases. Yet, acute cardiovascular events, such as a heart attack or stroke, often occur unexpectedly. That is because many people do not know they are at risk for such an event. Immunological researcher Amanda Foks and her colleagues…
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The right diagnosis and faster for women with heart problems
It often takes longer for women with heart problems to get the right diagnosis. In her Annie Romein-Verschoor Lecture, Professor Hester den Ruijter will talk about how hormones influence the heart and the importance of medical research that focuses specifically on women.
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The LeiCNS-PK3.0 model development and applications: Healthy-to- diseased CNS pharmacokinetic translation
PhD defence
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Another successful collaboration between Leiden Law School and LUMC
Researchers from Leiden Law School and the LUMC have received a grant for a joint research project. They will be looking into ways in which caregivers and patients can work together to come to a better decision.
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Why arteriosclerosis looks like an autoimmune disease
Arteriosclerosis bears great similarities to autoimmune diseases. Researchers from Leiden University show this in a new study they published in the renowned scientific journal Nature Cardiovascular Research. 'This discovery suggests that treatment methods for autoimmune diseases might also be effective…
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Curing diseases with lab-grown organs
Organs and tissues grown in the lab may in the future be able to cure people with organ failures. Micha Drukker, professor of Stem Cells, Developmental Biology and Technology for Innovative Drug Research, is convinced that the use of stem cells will make this possible. He will deliver his inaugural…
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How these young researchers are preparing for their first scientific conference
Three Psychology students will present a poster of their thesis research on Alzheimer’s and dementia at the international conference AAIC Neuroscience Next. ‘I remind myself to recognise - without fear or shame - when I don't know something.’
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ESOF session on vaccines: ‘Infectious diseases know no borders’
How can Europe lead the way in vaccine development that is fast and for all? To answer this pressing question, Professor of Vaccinology Meta Roestenberg is holding a panel session on 14 July at the EuroScience Open Forum in Leiden.
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Bram Slütter
Science
b.a.slutter@lacdr.leidenuniv.nl | +31 71 527 6208
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Advocating for gene therapies for rare diseases
‘If we don’t start talking about this, who else will?’ This is what Arjan Lankester, paediatrician/immunologist at the Leiden University Medical Center (LUMC) and Professor of Paediatrics, thought when it seemed that various extremely effective gene therapies for rare diseases would no longer be available…
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Seeking new concepts to treat diseases
Scientific Director of the Leiden Academic Centre for Drug Research (LACDR) Hubertus Irth: ‘We test substances and look for new concepts for treating disease.’
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Developing new therapies to fight muscle disease
Biophysicist Alireza Mashaghi and his collaborators are taking up the fight against muscular dystrophy: genetic disorders that cause muscle weakness. They want to inhibit the clumping of proteins that results in toxic aggregates. For this, the team receives 550,000 euros from Health Holland. The team…
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‘Heart rate and skin conductance predict romantic attraction’
Synchronised heart rates and skin conductance tell us that people are attracted to each other. This explains why we feel a romantic ‘click’ with some people and not with others. This is the result of research by psychologist Eliska Prochazkova from the Leiden Institute for Brain and Recognition, which…
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Better treatment of systemic autoimmune diseases requires close collaboration
Exceptional collaboration between physicians is needed to better understand and treat autoimmune diseases that cause inflammation in various organ systems.
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Hans Aerts
Science
j.m.f.g.aerts@lic.leidenuniv.nl | +31 71 527 2727
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New treatments for life-threatening disease sepsis
Due to the increasing resistance to certain antibiotics, the life-threatening condition sepsis is becoming harder to treat. For her PhD project, Leiden pharmacologist Feiyan Liu used mathematical modeling to find out how antibiotics can be used more effectively to cure sepsis.
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Maia Casna investigates respiratory disease in the past with an NWO PhD in the Humanities grant
Every year, an NWO PhD in the Humanities grant is awarded to a prospective PhD candidate at the Faculty of Archaeology. This year, the grant went to Maia Casna, enabling her to study respiratory disease in the past. ‘My hypothesis is that the rapid formation of cities in the medieval Netherlands, must…
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Elizabeth (Liesbeth) de Lange
Science
ecmdelange@lacdr.leidenuniv.nl | +31 71 527 6330
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Bart Verkuil
Faculteit der Sociale Wetenschappen
bverkuil@fsw.leidenuniv.nl | +31 71 527 3460
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Using low sample volumes to better understand brain diseases
Marlien van Mever delved into the analysis of tiny samples, cerebrospinal fluid from transgenic mouse models for example. She validated methods that can now be used to study brain diseases such as migraine and epilepsy. Van Mever will receive her PhD on 14 June.
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Proposed decision by Minister Kuipers: Children’s heart surgery to end in Leiden
Ernst Kuipers, Minister of Health, Welfare and Sport, announced on 13 February that he plans to remove children’s heart surgery from the Centre for Congenital Heart Defects Amsterdam - Leiden (CAHAL). He wants to concentrate this highly specialised care for children with congenital heart defects in…
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Echoes of the future
If an echo (or ultrasound) shows that a foetus has a heart or other defect, parents face difficult decisions. Then an idea of their child’s shorter and longer-term future is literally a matter of life and death. Haak will argue in her inaugural lecture that the cohort studies of rare diseases that are…
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Leiden interdisciplinary research opportunities in health and disease prevention
Are you a Leiden researcher looking for opportunities for interdisciplinary research and collaboration in the fields of local communities, health and disease prevention? If so, Health Campus The Hague is the right place for you. Take a look at these four examples of current research.
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Willem Fibbe
Faculteit Geneeskunde
w.e.fibbe@lumc.nl | +31 71 526 2271
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Philosopher of law Ali Kösedag: Hague heart, Leiden mind
In the Pioneers of Leiden University series we talk to past and present students who were the first in their family to go to university. In this fourth instalment: alumnus and philosopher of law Ali Kösedag (1992): ‘Philosophising about equality before the law in the Netherlands at an early-morning…
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Tim Koppert
Faculteit der Sociale Wetenschappen
t.y.koppert@fsw.leidenuniv.nl | +31 71 527 2727
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Katja Cardol
Faculteit der Sociale Wetenschappen
c.k.cardol@fsw.leidenuniv.nl | +31 71 527 5697
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Maia Casna
Faculteit Archeologie
m.casna@arch.leidenuniv.nl | +31 71 527 2727
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Jyothi Thrivikraman
Faculty Governance and Global Affairs
j.k.thrivikraman@luc.leidenuniv.nl | +31 70 800 9500
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Marit Ruitenberg
Faculteit der Sociale Wetenschappen
m.f.l.ruitenberg@fsw.leidenuniv.nl | +31 71 527 2727
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IBL Spotlights - Development & Disease
Lecture
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BEAT-COVID team discovers sugar-coated antibodies that predict disease progression
At the start of the COVID-19 pandemic, researchers from 15 departments at Leiden University Medical Center (LUMC) realised they could do more for patients if they joined forces. This is how the BEAT-COVID group has been able to rapidly gain knowledge about COVID-19, the role of the immune system and…
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Better treatment of skin diseases thanks to NWA grant of 11.7 million euros
Patients with skin diseases such as eczema and psoriasis, sometimes spend a lifetime searching for the right medication. To help these patients faster and better, scientists across the country are joining forces. The Next Generation ImmunoDermatology (NGID) project, with LACDR professor Robert Rissmann…
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Malformations in heart, eyes and nervous system: Nano-plastics disrupt growth
Nano-plastics cause malformations. Meiru Wang, researcher at the Institute of Biology Leiden, looked at the extreme effects polystyrene nano-particles could have, using chicken embryos as a model. Her results were quite alarming. Especially as nano-particles are everywhere. In the air, floating through…
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Challenge grant for research into autoreactive B cells in cardiovascular disease
At the division of BioTherapeutics, Amanda Foks, Bram Slütter and Ilze Bot have obtained a €4 million research grant from the HORIZON 2022 EIC Pathfinder Challenge “Cardiogenomics”, entitled “B-specific: B-cell related gene and protein markers with prognostic and therapeutic value for CVD”.
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How e-coaching helps people with chronic kidney disease to live more healthily
An e-coaching programme helps people with chronic kidney disease, particularly in areas that patients themselves want to work on. ‘A healthy lifestyle is important for patients with kidney disease: it can slow down the loss of kidney function and there will be fewer complications,’ Katja Cardol explains…
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Omar Al Sadeh: ‘My heart told me to go to Foreign Affairs’
Trail, FGGA’s internship platform will be one-year old in November. In the upcoming weeks, we will be interviewing some FGGA students who went on internships. What did they learn from their internships? And what tasks were assigned to them?
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'Migraine requires a gender-specific approach'
Migraine is a brain disease. If it were simple, we would have solved it already'. That is the title of the inaugural lecture delivered by Professor of Neurology Gisela Terwindt on Friday 3 June. In her speech she emphasises the importance of research into the differences between women and men with m…
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tour: 'Many people with MS do not link their cognitive symptoms to the disease'
In the MS Cognitietour, psychologists and neuroscientists from Leiden University discuss the latest scientific knowledge with MS patients and their loved ones. This leads to insights: 'One lady told how much stress she felt from all those caregivers around her bed.'
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Roeland Merks
Science
merksrmh@math.leidenuniv.nl | +31 71 527 7106
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Jordy van der Beek
Science
j.g.van.der.beek@cml.leidenuniv.nl | +31 71 527 2727
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Patrick van Hage
Science
p.van.hage@biology.leidenuniv.nl | +31 71 527 4950
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Joey Zuijdervelt
Science
j.l.zuijdervelt@lacdr.leidenuniv.nl | +31 71 527 6227
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Maria Yazdanbakhsh
Faculteit Geneeskunde
m.yazdanbakhsh@lumc.nl | +31 71 526 5067
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Coen van Hasselt
Science
coen.vanhasselt@lacdr.leidenuniv.nl | +31 71 527 3266
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Frits Rosendaal
Faculteit Geneeskunde
f.r.rosendaal@lumc.nl | +31 71 526 4037
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Annemarie Meijer
Science
a.h.meijer@biology.leidenuniv.nl | +31 71 527 4927
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ERC-grant for Sebastian Pomplun to cure disease by controlling gene expression with synthetic transcription factors
Sebastian Pomplun receives an ERC starting grant of 1.85 million Euros in five years. He wants to develop synthetic transcription factors that can enter cells and activate or deactivate specific genes. For example to disrupt cancer-related processes or to trigger the production of an important missing…