Universiteit Leiden

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PhD candidate

Vacancy number
Academic staff, PhD positions
Publication date
9 February 2021
Closing date
30 March 2021 Vacancy closed

The Faculty of Science and the Leiden Institute of Chemistry are looking for a

PhD candidate

Key responsibilities
The Faculty of Science and the Leiden Institute of Chemistry are looking for a PhD candidate to design and synthesize conformationally restricted paramagnetic NMR probes to study protein dynamics

Modern NMR spectroscopy can be used to study minor states of proteins that are important for function (relaxation dispersion NMR). This method could become much more powerful when married to paramagnetic NMR methods, having a major impact on the study of protein dynamics. The PhD student will carry out research leading to a PhD degree, and will design and synthesize conformationally restricted paramagnetic metal complexes, determine their conformations, tag proteins, and demonstrate their application in relaxation dispersion NMR spectroscopy. The PhD student must be flexible and communicative and able to work in both (in)organic and biochemistry labs and learn advanced protein NMR methods.

Selection criteria

  • Master degree in (in)organic chemistry, or equivalent;
  • Proven interest in NMR spectroscopy;  
  • Proven interest in protein structure and function;            
  • Proficient in English;
  • Excellent communication skills.

Our organisation
The Faculty of Science is a world-class faculty where staff and students work together in a dynamic international environment. It is a faculty where personal and academic development are top priorities. Our people are committed to expand fundamental knowledge by curiosity and to look beyond the borders of their own discipline; their aim is to benefit science, and to make a contribution to addressing the major societal challenges of the future.

The research carried out at the Faculty of Science is very diverse, ranging from mathematics, information science, astronomy, physics, chemistry and bio-pharmaceutical sciences to biology and environmental sciences. The research activities are organised in eight institutes. These institutes offer eight bachelor’s and twelve master’s programmes. The faculty has grown strongly in recent years and now has more than 2.200 staff and almost 4,200 students. We are located at the heart of Leiden’s Bio Science Park, one of Europe’s biggest science parks, where university and business life come together.

The chemistry and life science research in the Leiden Institute of Chemistry (LIC) is organized around two major research areas: ‘Chemical Biology’ and ‘Energy & Sustainability’. The institute’s research themes illustrate the central position of chemistry between biology, medicine and physics. The various research topics carried out within these themes are ideal for executing interdisciplinary research. For more information, see the website of the Faculty of Science.

Terms and conditions 
We offer a full-time 1 year term position for initially one year. After a positive evaluation of the progress of the thesis, personal capabilities and compatibility the appointment will be extended by a further three years. Salary range from 2.395,- to € 3.061,- gross per month (pay scale P in accordance with the Collective Labour Agreement for Dutch Universities).

Leiden University offers an attractive benefits package with additional holiday (8%) and end-of-year bonuses (8.3 %), training and career development and sabbatical leave. Our individual choices model gives you some freedom to assemble your own set of terms and conditions. Candidates from outside the Netherlands may be eligible for a substantial tax break. For more information, see the website.

All our PhD students are embedded in the Leiden University Graduate School of Science. Our graduate school offers several PhD training courses at three levels: professional courses, skills training and personal effectiveness.

Leiden University is strongly committed to diversity within its community and especially welcomes applications from members of underrepresented groups.

Enquiries can be made to Mark Overhand, email m.overhand@chem.leidenuniv.nl or Marcellus Ubbink, email m.ubbink@chem.leidenuniv.nl.

To apply for this vacancy, please send an email to Jessica van Krimpen, e-mail j.e.van.krimpen@lic.leidenuniv.nl. Please ensure that you upload the following additional documents quoting the vacancy number:

  • Letter of motivation addressed to Marcellus Ubbink, including a statement why you are suited for this position;
  • Curriculum vitae;
  • Transcripts of bachelor and master curriculum courses, including grades;
  • Three references, including names, affiliations and email addresses.

This position is re-advertised (former vacancy number 20-439). Applicants who applied before do not need to apply again. Only applications received no later than 30 March 2021 can be considered. The procedure will be ended as soon as a suitable candidate has been found.


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