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1,185 search results for “bart cancer metastasis” in the Public website

• Cell-autonomous and host-dependent CXCR4 signaling in cancer metastasis: insights from a zebrafish xenograft model Research output

  Promotor: A.H. Meijer, Co-promotor: B.E. Snaar-Jagalska

• Image-based phenotypic screening for breast cancer metastasis drug target discovery Research output

  The main aim of this thesis was to unravel the signaling and regulatory networks that drive tumor cell migration during breast cancer metastasis.

• multifaceted roles of Grainyhead-like transcription factor-2 in breast cancer Research output

  Breast cancer is the most common cancer in women worldwide. Metastasis, the process by which cancer cells spread to other parts of the body, makes treatments less effective. It is important to unravel the mechanism of metastasis.

• Mechanisms of Ewing sarcoma metastasis: biochemistry and biophysics Research output

  Promotor: T. Schmidt, Co-Promotor: B.E. Snaar-Jagalska

• Discovery of metastasis promoting candidate drug targets Research project

  Discovery of metastasis promoting candidate drug targets

• xenograft model: identification of novel mechanisms driving prostate cancer metastasis Research output

  Prostate cancer (PCa) is one of the most prevalent cancer in males.

• Identification of novel targets in prostate cancer progression Research output

  Promotor: Prof.dr. B. van de Water, Co-promotor: E.H.J. Danen

• Cell adhesion signaling: dynamics, migration, and metastasis Research project

  Cell adhesion signaling

• Novel regulators of prostate cancer stem cells and tumor aggressiveness Research output

  Promotor: R.C.M. Pelger Co-Promotor: G. van der Pluijm

• RNA splicing in breast cancer progression Research output

  In this thesis, we aimed to better understand the underlying mechanisms involved in TNBC progression and metastasis formation and discover new targets to reduce breast cancer related deaths.

• Cancer Drug Target Discovery Research project

  We focus on a better understanding of the mechanisms of cancer drug resistance and metastasis.

• Pulling the strings on anti-cancer immunity Research output

  Promotores: J. Jonkers, K.E. de Visser

• Cancer Therapeutics and Drug Safety Cell Systems and Drug Safety

  In this research group, headed by Bob Van de Water, cell signaling programs that underlie adverse drug reactions as well as cancer development and progression are unraveled. Adverse drug reactions involve cell injury in critical target organ cells which leads to the activation of cellular stress response…

• Cancer Drug Target Discovery

  In this research group, headed by Prof. Erik Danen, the aim is to unravel cellular signaling mechanisms in normal and diseased cells, with a long-standing interest in cell adhesion signaling. In complex multicellular organisms such as ourselves, a division of labor emerges where different tissues and…

• PI3K signaling and adherens junctions in invasive lobular breast cancer Research output

  Invasive lobular carcinoma (ILC) is the second most common type of breast cancer.

• Cancer pathogenesis and therapy Research Dossier

  With cancer, a person’s body cells grow uncontrollably. Putting together a detailed picture of how this comes about makes it possible to develop efficient therapies. Researchers at the Leiden University Medical Centre (LUMC) and Leiden University are working together to gain a better understanding…

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  Bart Bulsing Technical Information Manager / Draftsman

  Service Unit Real Estate

  b.m.bulsing@vastgoed.leidenuniv.nl | +31 71 527 1203

• 
  Bart Appelhof Postdoc / guest

  Faculty of Science

  b.appelhof@biology.leidenuniv.nl | +31 71 527 2727

• 
  Bart Lenselink Guest Scientist

  Faculty of Science

  e.b.lenselink@lacdr.leidenuniv.nl | +31 71 527 2727

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  Bart Hoenen Advisor Entrepreneurship (guest

  Administration and Central Services

  b.m.j.hoenen@bb.leidenuniv.nl | +31 71 527 2531

• 
  Bart Schreuders Researcher/lecturer

  Faculty of Law

  h.g.schreuders@law.leidenuniv.nl | +31 71 527 2727

• 
  Bart Collard External PhD candidate

  Faculty of Law

  b.j.collard.2@umail.leidenuniv.nl | 071 5275200

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  Bart Mertens

  Faculteit Geneeskunde

  b.mertens@lumc.nl | +31 71 527 6817

• 
  Bart Gorissen Lecturer

  Faculty of Law

  b.j.e.gorissen@law.leidenuniv.nl | 071 5272727

• Exploring Grainyhead-like 2 target genes in breast cancer Research output

  The objective of this study was to investigate the expression and function of GRHL2 in different breast cancer subtypes.

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  Bart Wentholt Participating Coordinator MDA Open Access

  Leiden University Library

  b.l.r.wentholt@library.leidenuniv.nl | +31 71 527 2727

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  Bart Vogelaar Assistant professor

  Social & Behavioural Sciences

  b.vogelaar@fsw.leidenuniv.nl | +31 71 527 6022

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  Bart Alewijnse Programmer/lab technician

  Faculty of Humanities

  b.alewijnse@hum.leidenuniv.nl | 071 5272320

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  Bart Barendregt Vice-dean of Research/ Professor Anthropology of Digital Diversity

  Social & Behavioural Sciences

  barendregt@fsw.leidenuniv.nl | +31 71 527 3475

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  Bart Schermer Professor Law and Digital Technology

  Faculty of Law

  b.w.schermer@law.leidenuniv.nl | +31 71 527 8838

• 
  Hanneke Leegwater Guest

  Faculty of Science

  h.leegwater@lacdr.leidenuniv.nl | 071 5272727

• synergistic effects of Chinese herbal medicine and natural compounds on cancers Research project

  What are the biological effects of Chinese herbal medicine in regulation of cancer cell metastasis?

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  Bart Zantvoort Lecturer

  Faculty of Humanities

  f.w.zantvoort@hum.leidenuniv.nl | 071 5272727

• Computational modeling of tumor growth and metastasis and the role of the immune system in tumor destruction Research project

  In this project, we aim to obtain a quantitative understanding of the role of the immune system in tumor regression, of the role of tumor cell heterogeneity in cancer growth and of tumor cell migration properties.

• Cancer and heredity Research Dossier: Cancer pathogenesis and therapy

  Some people are predisposed to develop cancer. Mutations in genetic material that increase a person’s chances of developing cancer can already be present at birth. Researchers are closely examining these mutations to learn more about how cancer begins to develop.

• BRCA1-associated breast cancer: finding new weapons for an old villain Research output

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  Bart Roep Professor Diabetology, in particular the immunopathology of type 1 diabetes mellitus

  Faculteit Geneeskunde

  b.o.roep@lumc.nl | +31 71 526 3869

• 
  Bart Wielders PhD candidate / self funded

  Faculty of Governance and Global Affairs

  b.wielders@fgga.leidenuniv.nl | 070 8009500

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  Bart Kramer PhD candidate / guest

  Faculty of Science

  b.kramer@lacdr.leidenuniv.nl | +31 71 527 4220

• Cancer Pathogenesis and Therapy Research project

  Cancer represents a formidable current and future global health challenge. The LUMC medical research profile Cancer Pathogenesis and Therapy charges this challenge by developing and implementing innovative patient-tailored, multimodal diagnostic methods and treatment modalities.

• Development of novel anti-cancer strategies utilizing the zebrafish xenograft model Research output

  In this thesis, we will utilize embryonic zebrafish tumour models to understand the interaction between engrafted human cancer cells and macrophages from the host, test drug administration modalities and anti-cancer efficacies of newly-developed PDT and PACT compounds, and test a light-triggered liposomal…

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  Bart van Horck PhD candidate (extern)

  Faculty of Governance and Global Affairs

  b.c.a.van.horck@fgga.leidenuniv.nl | +31 70 800 9502

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  Bart van Lieshout PhD candidate

  Faculty of Science

  b.van.lieshout@lacdr.leidenuniv.nl | +31 71 527 6209

• 
  Bart de Vries Guest

  Social & Behavioural Sciences

  h.e.j.de.vries@fsw.leidenuniv.nl | +31 71 527 2727

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  Bart de Jongh Lecturer

  Social & Behavioural Sciences

  b.n.de.jongh@fsw.leidenuniv.nl | 071 5272727

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  Bart van der Wal Professor Orthopaedics

  Faculteit Geneeskunde

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  Bart van der Hoogt Trainee

  Faculty of Science

• Discovery of BUB1 kinase inhibitors for the treatment of cancer Research output

  The spindle-assembly checkpoint (SAC) is a safety mechanism which secures accurate chromosome segregation during mitosis.

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  Bart Labuschagne Lecturer

  Faculty of Law

  b.c.labuschagne@law.leidenuniv.nl | 071 5277540

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  Bart Joosen Guest lecturer

  Faculty of Law

  e.p.m.joosen@law.leidenuniv.nl | 071 5272727