This project investigates the role of art in the public and academic debate on biosolar energy

Social anxiety runs in families, but the neurobiology underlying this genetic vulnerability is until now largely unknown. The unique Leiden Family Lab study on Social Anxiety Disorder (LFLSAD) aims to broaden our knowledge with respect to this genetic susceptibility.

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Although exposure therapy is the gold-standard treatment of posttraumatic stress-disorder (PTSD), only half of the patients adequately benefit from it. Based on recent insights into the mechanisms of extinction, this project examines strategies and techniques to improve exposure treatment outcome in…

The precise psychobiological mechanisms leading to chronic physiological stress responses have not been sufficiently explained, although stress is a major risk factor for disease and early death. A problem for conventional stress theory is that most of these responses seem to occur in situations without…

Introduces a novel trope of photographic images dealing with states of mental disorders; focuses on photographs that visualize disturbed corporeal and mental perceptions of the world and connects medium-specific characteristics of photography to concepts from mental disorder studies.

How to come to valid risk stratification of alcohol use disorder?

One of the current research projects funded by the profile area Political Legitimacy is the research group From Disorder to Order: Conflict and the Resources of Legitimacy.

Our mission is to advance the understanding of mental health of individuals with a history of stress and/or trauma through rigorous interdisciplinary research, integrating insights from clinical psychology, neurobiology, and social sciences. We are committed to translating our findings into innovative…

In this thesis we use Josephson and noise scanning tunneling microscopy for the study of conventional, unconventional (iron-based) and disordered superconductors. On the one hand, Josephson scanning tunneling microscopy allows us to directly visualize the superfluid density with high spatial resolut…

This thesis is devoted to an in-depth examination of the various effects of disorder in the cuprate high-temperature superconductors.

The key question addressed in this family study is whether the psychophysiological and neurocognitive abnormalities often reported in SAD patients are heritable and can thus be found in family members of SAD patients as well. Determination of heritability of these deficiencies is essential for endophenotyping.…

Leiden researchers have found clues to why a rare pregnancy disorder is mild in some babies but life-threatening in others. Their discovery opens the door to a test that could identify severe cases during pregnancy. Fortunately, a treatment already exists.

How does stress affect different components of behavioral impulsivity and aggression in patients with Borderline Personality Disorder compared to clinical controls (patients with Attention Deficit Hyperactivity Disorder) and healthy controls?

Why do children with an Autism Spectrum Disorder (ASD) have difficulties with acquiring emotion regulation skills; and how is this related to their social impairments and comorbid psychopathology?

Does an Emotional Working Memory Training show a beneficial transfer effect on emotion regulation (reappraisal) capacities in patients with Borderline Personality Disorder?

How do dissociative states affect the ability to suppress emotional distraction (in the context of a working memory task) in patients with Borderline Personality Disorder?

Which criteria do ED patients and therapists evaluate as most relevant for recovery? Do patients and therapists differ in their evaluations? Do eating disorder patients differ from a healthy control group in their scores on the Recovery Scale?

What is the role of emotion regulation in coping with interpersonal feedback?

Neurodegenerative diseases pose a large medical and societal challenge. The etiology of these diseases is still poorly understood, which makes drug discovery for these diseases difficult.

Dissertation

We talk to Justin, who was diagnosed with Bipolar Disorder type 1 over 14 years ago. Justin is very candid and talks about his first manic episode at the age of 28, and how he learned to live a stable life. Justin is doing well, and he owes this in particular to his own perseverance. What do you experience…

It often takes a long time for people with an eating disorder to seek help and receive treatment. eHealth could be a solution, PhD candidate Pieter Rohrbach has discovered.

Have you ever experienced the feeling of awkwardness when attending a party where you didn’t know anybody? Ever felt shy at a party within the first few minutes? While this feeling is labelled loosely as feeling socially anxious, social anxiety disorder goes to a much further extent.

Leiden biotech startup Azafaros has successfully completed a funding round, raising 25 million euros of investments for developing treatments of rare metabolic disorders. The company holds exclusive license to a library of novel patented compounds discovered by experts from Leiden University.

It was already known that social anxiety disorder often affects more than one person in the same family. But research by PhD student Janna Marie Bas-Hoogendam has now shown that there are genetic brain characteristics that are associated with social anxiety. The PhD ceremony will take place on 14 Ja…

‘Raising awareness of the disorder is crucial since borderline personality disorder (BPD) still faces considerable stigma ’, says Anne Krause-Utz (Clinical Psychology) . Together with an international team of excellent scientists, Krause-Utz provides an update of current knowledge about this disorder,…

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Investigating neurobiological endophenotypes of Social Anxiety Disorder

As a professor, Natasha Appelman-Dijkstra understands better than anyone how important it is to recognise bone and mineral conditions at an early stage. She emphasises the importance of flexibility and collaboration for better care, groundbreaking research and strong education.

After studying Life Science and Technology, David Louwrier conducted his PhD research at LUCAS about bioart and societal debates around biotechnology. Now that his PhD thesis has been submitted, David is developing educational material about the societal aspects of the biobased economy.

Many primary school children suffer from anxiety and their numbers are increasing. Psychologists from the Knowledge Center Anxiety & Stress (KAS) are developing and researching preventive training.

Stressful events and a lack of support from the environment are both consequences and causes of mood swings in people with a bipolar disorder. This is the finding of PhD research by Leiden clinical psychologist Manja Koenders. PhD defence 7 April.

Do general practitioners recognize children with or at risk of problematic anxiety and is there a pattern that might help differentiate those with and without anxiety disorders in general practice?