92 search results for “nucleaire proliferation” in the Public website
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The Proliferation of Dissenting Opinions in International Law
On 8 July 2020, Andres Sarmiento Lamus defended his thesis 'The Proliferation of Dissenting Opinions in International Law'. The doctoral research was supervised by Prof. L.J. van den Herik and Prof. Y.A.A.S. Radi (UCLouvain).
- Managing the nuclear threshold: Non-nuclear allies in NATO decision-making
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Targeted Therapy for Triple-Negative Breast Cancer
The research described in this thesis focused on identifying novel drug targets and synergistic combinations for triple-negative breast cancer (TNBC), a virulent subtype of breast cancer with a dismal prognosis and limited therapeutic options.
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Composition and function of integrin adhesions
Integrins play an essential role in multicellular life by connecting cells to the extracellular matrix.
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Understanding coercive nuclear reversal dynamics: a comparative case study of US coercive diplomacy against the nuclear programs of Iran, Libya
What are the conditions under which coercive diplomacy can compel a State to abandon its nuclear weapons program?
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Off the wall: characterisation and exploitation of a cell wall deficient life style in filamentous actinomycetes
Almost all bacteria are enveloped by a cell wall that provides cellular protection.
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Exploring and exploiting CD8+ T cell proliferation
PhD defence
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Research
An overview of the research at the Cancer Dug Target Discovery group.
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The rise of open-source intelligence
Damien van Puyvelde and Fernando Tabárez Rienzi examine the evolution of Open-Source Intelligence (OSINT).
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RNA splicing in breast cancer progression
In this thesis, we aimed to better understand the underlying mechanisms involved in TNBC progression and metastasis formation and discover new targets to reduce breast cancer related deaths.
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Involvement of host and bacterial factors in Agrobacterium-mediated transformation
Agrobacterium tumefaciens, a gram-negative plant pathogen belonging to the family Rhizobiaceae, is the causative agent of crown gall disease, which can affect many plant species including agronomically important ones.
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Osteosarcoma: searching for new treatment options
Promotores: B. van de Water; P. Hogendoorn; J. Bovée Co-Promotor: E.H.J. Danen
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Regulation of autophagy-related mechanisms during bacterial infection
Autophagy is a fundamental degradative process, maintaining cellular homeostasis and functions in host defense against intracellular pathogens, including mycobacteria and Salmonella.
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Disrupting the transcriptional machinery to combat triple-negative breast cancer
Triple-negative breast cancer (TNBC) is a subtype of breast cancer characterized by limited treatment options and unfavorable clinical outcomes. Therefore, the research described in this thesis focused on the exploration of novel targeted therapies for TNBC.
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Selective autophagy in host defense against mycobacterial infection
The effective treatment of tuberculosis (TB) remains a major challenge to global health.
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Restraint under conditions of uncertainty: Why the United States tolerates cyberattacks
This new article by Monica Kaminska is part of a special issue for Journal of Cybersecurity, based on a selection of contributions from THe Hague Program for Cyber Norms' 2019 Conference.
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Multiscale mathematical biology of cell-extracellular matrix interactions during morphogenesis
During embryonic growth, cells proliferate, differentiate, and collectively migrate to form different tissues at the right position and time in the body.
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Enhancing the societal impact of academic publications (Creatieve Industrie – NWO KIEM)
The central goal of academic publishers is the dissemination of the results of research and scholarship. Their audiences can generally be divided into two categories. Academic publications are firstly made accessible to the scholarly community, so that these texts can form the input for new academic…
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Van der Heijden Chair Social Justice
On the occasion of prof Paul van der Heijden’s stepping down as Rector Magnificus and President of the Executive Board of Leiden University in 2013 the Chair bearing his name on Social Justice was established. It was a “farewell present” of the Leiden University to it’s Rector.
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International Organisation
This research cluster is a part of the Institute of Political Science’s research programme ‘Institutions, Decisions and Collective Behaviour’. Its members examine the sources, design, effects and contestation of norms, rules, institutionalised practices and formal organisations that operate across national…
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Buddhist Astrology and Astral Magic in the Tang Dynasty
Jeffrey Kotyk defended his thesis on 7 September 2017
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Functions of P38 and ERK kinases in zebrafish early development
Promotor: Prof.dr. H.P. Spaink Co-promotor: Dr. B.E. Snaar
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The Role of Modern International Commissions of Inquiry
On 5 September 2017, Alessandro Tonutti defended his PhD dissertation
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Cell-autonomous and host-dependent CXCR4 signaling in cancer metastasis: insights from a zebrafish xenograft model
Promotor: A.H. Meijer, Co-promotor: B.E. Snaar-Jagalska
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Muslim Youth and the 9/11 Generation
On young Muslims seeking to understand their place and make their way in a transformed world.
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Cancer Drug Target Discovery
In this research group, headed by Prof. Erik Danen, the aim is to unravel cellular signaling mechanisms in normal and diseased cells, with a long-standing interest in cell adhesion signaling. In complex multicellular organisms such as ourselves, a division of labor emerges where different tissues and…
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In vivo modelling of Ewing sarcoma in zebrafish
Promotores: Prof.dr. P.C.W. Hogendoorn & Prof.dr. H.P. Spaink, Co-promotor: Dr. B.E. Snaar-Jagalska
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Making migration and migration policy decisions amidst societal transformations (PACES)
PACES is an innovative, inter-disciplinary and multi-level research project that asks, How do changes in society, individual life experiences and migration policy shape decisions to stay or to migrate over time and across countries? And how can this knowledge inform future migration policies and gov…
- Entangled Universals
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Explant cultures of atopic dermatitis biopsies maintain their epidermal characteristics in vitro
Atopic dermatitis (AD) is a common inflammatory skin disorder characterised by various epidermal alterations. Filaggrin (FLG) mutations are a major predisposing factor for AD and much research has been focused on the FLG protein.
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Contagious Territories
In this project we think about the relationship between territory and contagion. Tracing the historical, political, and conceptual linkages between territorial bordering and migration on the one hand and disease related phenomena like contagion, immunity, and inoculation on the other, we ask how the…
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UN Sanctions and International Law
Are UN sanctions regimes in need of further formalization in terms of substantive design, procedural architecture and with a view to regulating and governing the interplay with other regimes?
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[sbb] INSCONS: International Scientific Consortia
Addressing Global Challenges through International Scientific Consortia
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NL ARMS Netherlands Annual Review of Military Studies 2020
This open access volume surveys the state of the field to examine whether a fifth wave of deterrence theory is emerging. Bringing together insights from world-leading experts from three continents, the volume identifies the most pressing strategic challenges, frames theoretical concepts, and describes…
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About the project
This project studies how Islamic charitable networks in seeking to address global needs position themselves as universalist projects, entangled with Western humanitarianism and neoliberal welfare regimes.
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The aging B cell landscape in atherosclerosis
In this thesis, single-cell approaches were applied to characterize the impact of aging on the immunological B cell landscape in different models of atherosclerotic cardiovascular disease, with the goal to identify and study new B cell-associated biomarkers and therapeutic targets to halt atherosclerosis…
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Decent work
Decent work involves opportunities for work that delivers a fair income, care for occupational health and safety, freedom for people to organize and equality of opportunity and treatment for all women and men. The Labour Law department at Leiden University conducts research and provides education on…
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Fighting in God’s Name
This book underscores the interplay between religion and politics (local and global) in the production, escalation, management, mitigation, and resolution of conflict.
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From Clients to Citizens? Emerging Citizenship in Democratizing lndonesia
Democratic citizenship refers to the capacity and willingness of citizens to actively influence the functioning of state institutions. While considered a vital correlate of democratization and the rule of law, its largely western-oriented literature rarely studies the forms of democratic citizenship…
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About CompaRe
Common challenge: unique circumstances
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Microbial enzymes for degradation and upcycling of natural and non-natural polymers
Learning from nature and utilizing microbial biodiversity to identify and characterize enzymes for degradation and upcycling of plastics and other polymeric materials.
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About
Leiden University has long history of research and teaching on Asian traditions, with a focus on language and philology, history, religious studies, philosophy, law and literature. Leiden has in the last thirty years also built up an equally impressive strength in the study of modern and contemporary…
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Plenary speakers
We’re delighted to announce our plenary speakers.
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CARMA
An increasing number of researchers in the social sciences, humanities, and arts (SSH+A) are working with non-traditional research outputs (NTROs), such as films, performances, and sound recordings. However, these forms of research often receive little recognition within the digital scholarly infrastructure,…
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Representation and Political Parties
This research cluster is a part of the Institute of Political Science’s research programme ‘Institutions, Decisions and Collective Behaviour’. Its members focus on the democratic role of citizens and the representative links between voters and politicians.
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Entangled Universals of Transnational Islamic Charity
This project studies how Islamic charitable networks in seeking to address global needs position themselves as universalist projects, entangled with Western humanitarianism and neoliberal welfare regimes. It seeks to understand how and to what extent contemporary transnational Islamic charitable networks…
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CD11b+Gr-1+ myeloid-derived suppressor cells reduce atherosclerotic lesion development in LDLr deficient mi
Publication by: Amanda Foks, Gijs van Puijvelde, Jolien Wolbert, Mara Kröner, Vanessa Frodermann, Thomas van der Heijden, Peter van Santbrink, Louis Boon, Ilze Bot and Johan Kuiper. Cardiovascular Research. 2016;111(3):252-261.
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In the media: Martijn Nouwen's research into EU tax body
In het onderzoek van docent Martijn Nouwen wordt voor het eerst aan het grote publiek blootgelegd hoe de ‘geheime’ Europese Gedragscodegroep er niet in is geslaagd om verschillende vormen van schadelijke belastingconcurrentie uit te bannen.
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Targeting gun violence & trafficking in Europe
To assess the impact of illicit firearms trafficking on gun violence, this research looks at the scope, characteristics and contexts of firearm violence, and also the scope and nature of firearms trafficking in Europe since the new millennium. Nils Duquet, Dennis Vanden Auweele and Marieke Liem created…
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Towards a political ontology of violence: reality, image and perception
The aim of this project is to study what makes an act or form of violence a specifically political reality.