Source: International Journal of Cosmetic Science, Volume 37, Number 1, pp. 148-148 (2015) ISBN: 0142-5463

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The barrier function of the skin is primarily provided by the stratum corneum (SC), the outermost layer of the skin. Skin barrier impairment is thought to be a primary factor in the pathogenesis of atopic eczema (AE).

Atopic eczema is a skin disease with increasing incidence currently affecting 25% of the paediatric population. In atopic eczema the skin barrier function is reduced. This barrier is formed by the outermost layer of the skin called the stratum corneum (SC). The SC consists of terminally differentiated…

OBJECTIVES: To determine whether the lipid/protein ratio and the total dry SC mass per surface area are related with the skin barrier function of controls and AE patients.

Pharmacologist Walter Boiten developed a new method to determine the amount of lipids in a person's skin. With this method he tested the effects of a new cream he developed for eczema patients. The first results are promising. Boiten defends his dissertation on 15 January.

An important feature of atopic eczema (AE) is a decreased skin barrier function. The stratum corneum (SC) lipids - comprised of ceramides (CERs), free fatty acids (FFAs) and cholesterol - fulfill a predominant role in the skin barrier function.

Source: Journal of Investigative Dermatology, Volume 135, pp. S59-S59 (2015)

How are the epidermal lipid pathways involved in health and disease.

Promotor: J. A. Bouwstra

This dissertation provides a thorough review of the words belonging to the oldest layer of Germanic loanwords in Proto-Slavic and answers the question of how these words were adapted to the Proto-Slavic accentual system.

Tineke Berkers has won an award for outstanding contribution for her poster at the Gordon Research Conference at Waterville Valley, USA.

Below we present our past and future events of the Multigreen project

Media all around the world reported about it: the most detailed images yet seen of galaxies, shot by radio telescope LOFAR. The international team behind these amazing results were led by Leah Morabito at Durham University and included three talented Leiden astronomers.

‘The Netherlands’ response to coronavirus is inconsistent.’ These are the words of Leiden political scientist Arjen Boin, an expert in crisis management. Vulnerable groups such as the elderly need more personalised advice. ‘It would be better to cancel bridge tournaments than football games.’

Pharmacist-clinical pharmacologist Robert Rissmann has been appointed Professor of Translational Dermatology. This extraordinary professorship has been created jointly by the Leiden Academic Centre for Drug Research (LACDR) and the Centre for Human Drug Research (CHDR) to strengthen their partnership…

People with relatively high levels of lipids in their blood are less likely to develop allergic conditions such as eczema and asthma. These lipids cause genes that play a key role in allergic reactions to be less active. Researchers from the Leiden University Medical Center (LUMC) have published an…

In dermatology, there should be a high level of multidisciplinary collaboration among institutes and specialists, Professor of Translational Dermatology, Robert Rissmann, will say in his inaugural lecture on 8 July. He is building an infrastructure that will put pre-clinical and clinical skin research…

This research project is an integral part of its mother-programme NEXUS1492 ERC Synergy Project directed by Prof. Corinne Hofman. Overarchingly, it aims at understanding and bridging from the archaeological perspective the late pre-colonial and early colonial history of the Southeastern Caribbean macroregion…