Zebrafish is an excellent model organism for studying various human diseases. Due to opaqueness of the adult phase, in vivo studies are restricted to early embryonic stages. This raises the need for rapid sensitive and non-invasive in vivo imaging methods to follow developmental processes, not only…

Facilitating direct citizen participation through online channels is considered as an opportunity for including harder to reach groups in participation.

Promotores: C.A.J. Knibbe; J.N. van den Anker, Co-promotores: H.P.A. van Dongen; B. van Ramshorst

Is the current existing legal framework on compulsory and voluntary care - for vulnerable young adults (between the ages of 18 to 23) - in need of revision? And if so, what kind of amendments would be advisable?

On December 11th, Andreea Geambasu succesfully defended her doctoral thesis and graduated. The Leiden University Centre for Linguistics congratulates Andreea on this great result.

ADHD&me is a new cognitive-behavioural therapeutic intervention for young adults (16–25 years old) with ADHD, specifically aimed at improving self-esteem. In this study, we are conducting a Randomized Controlled Trial (RCT) to examine whether this intervention improves self-esteem and whether related…

The aim of this thesis is to expedite and ensure the systematic accuracy of clearance scaling from adults to paediatric patients, with a special focus on drugs undergoing hepatic metabolism.

The aim of this project is to investigate the (cost)effectiveness of two innovative forms of trauma-focused therapy for patients with childhood abuse related PTSD. The ultimate goal is to improve quality of care and contribute to treatment innovation for this severely ill target population.

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Quantifying physical activity (using accelerometers) and combining the frequency and intensity of activities with health data (brain MRI, traditional clinical parameters and metabolomics) is of utmost importance to monitor mobility and health among older individuals and study health promotion during…

On Monday November 7th the research outcome ‘Involuntary (after) care for vulnerable young adults? A study to the legal possibilities for the provision of (involuntary) care to vulnerable young adults after child protection’ was presented to the members of the Parliament.

On Friday 16 April, the webinar 'Children and young adults in contact with the law: Systemic vulnerabilities and institutional responses' will take place. The webinar is organised by Eva Schmidt LL.M, Dr. Anna Pivaty (Radboud University/Maastricht University) and Dr. Stephanie Rap, with the support…

Edward Elgar has recently published an edited volume entitled “Realising Protection from Age Discrimination: International, Regional, and National Perspectives”. The book has been edited by Helen Meenan (visiting professor at Kingston University, UK) and Christa Tobler (Europa Institutes of the Universities…

Behavioral and neural mechanisms underlying risky decision-making in adolescents

This talk will assess the place of adult language acquisition as an explanatory factor in syntactic change, making the case that certain changes can only be understood fully from this perspective. I will present a theory of syntactic “L2-difficulty” in terms of feature interpretability, and some preliminary…

The prevalence of obesity (BMI >40 kg/m2) has increased rapidly over the recent years, not only in adults, but also in children and adolescents.

How can we improve quality of life and study success in young, high-functioning adults with autism?

Prof. dr. R.R.J.M. Vermeiren dr. W.A. Ester dr. L.A. Nooteboom

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In this thesis, two potential therapeutic targets for diabetic nephropathy were dentified and investigated. First, we show that glomerular clusterin is upregulated in diabetic nephropathy and demonstrated that recombinant clusterin protein can protect the podocytes against oxidative stress in vitro.…

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Education and Organisation Development

During the Leiden Science Family Day, you can take part in various workshops. You can also watch various demonstrations. Where will you go?

Can playing certain games decrease cognitive decline or even enhance cognitive performance in the aging population?

During the Leiden Science Family Day, you will visit places that are normally closed to the public: go backstage at the Faculty of Science!

We aim to conduct as few animal experiments as possible. We are continually exploring methods to Replace, Reduce, and Refine animal experiments, commonly referred to as the three Rs. Additionally, we assess each study to ensure the implementation of the 3Rs has been maximised. The Animal Welfare Body…

This project investigates which aspects of social media content adolescents attend to and how these relate to their credibility judgments, aiming to systematically understand their susceptibility to misinformation and inform effective educational programs that foster youth’s resilience to misinforma…

Childhood obesity is an increasing health issue. In the first part of this thesis comorbidities in children with obesity were studied, concerning the diagnostic process and dosing regimens.

A neurobiological perspective on individual differences in social competence

Childhood sexual abuse is a common problem, with approximately one in five girls and one in 13 boys worldwide experiencing some form of sexual abuse before the age of 18. Despite its high prevalence, many individuals remain silent about these experiences, often delaying disclosure for years, with one…

This project introduces primary school children (8-12 years) to science and archaeology.

Platform Opleiding, Onderwijs en Organisatie Ltd (PLATO). PLATO is committed to learning, learning in schools, learning in work environments, learning in life and life.

Across cultures, parents help their children master the social and linguistic codes needed in adult life. Recent research on language socialization found important cross-cultural differences, pointing out the need for more diversity for a full understanding of this process.

Promotor: C.A.J. Knibbe, Co-promotor: J.J. Boelens, R.G.M. Bredius

The more opportunities a child has to learn and develop, the stronger his or her future position in society. Leiden University investigates how the brain picks up information, and how learning processes can be influenced positively.

A higher education often helps to learn additional languages. Here, I will present a study about why the size of this effect may depend on the similarity of the L1 to the target language, expecting that a higher education facilitates both language-independent literacy skills as well as transfer of L1…

PAIR, Psychoeducational Assessment, Intervention and Rehabilitation, is the online Open Access journal associated with ENPAIR.

Everyone is welcome at the Leiden Science Family Day. We have set up a programme with a variety of activities for children, teenagers and adults.

Clearance is the most important pharmacokinetic parameter for drug dose selection. Pharmacokinetic information is typically first available in the adult population, and in general only limited pharmacokinetic data are available in children when drugs enter into the market. It is therefore of the utmost…

How does economic downturn affect pre-existing democratic values and intergroup attitudes? Does economic downturn lead people to lose support for democracy and does it raise perceptions of intergroup threat? Is the potential effect of economic downturn on these political attitudes conditional upon earlier…

Leiden University has much to offer, so why not come and visit? We’d like to meet you.

Education and Organisation Development

Mensen worden steeds ouder. Soms in goede gezondheid, soms zijn er uitdagingen die de kop op steken. Met onderzoek, innovatief onderwijs en co-creatie met oudere mensen werken studenten van de master Health, Ageing and Society aan oplossingen voor deze uitdagingen.

We investigate the molecular basis underlying health and disease and provide answers to existing and emerging health problems. Within this theme, we study diseases ranging from rare genetic disorders to cancer and infectious diseases. We make use of a wide variety of model systems and pursue diverse…

New and reemerging infectious diseases call for innovative and efficient control strategies of which fast vaccine design and development represent an important element.

How does stress affect different components of behavioral impulsivity and aggression in patients with Borderline Personality Disorder compared to clinical controls (patients with Attention Deficit Hyperactivity Disorder) and healthy controls?