Leiden University, together with Utrecht University, the LUMC and 10 other Dutch universities and institutes, has been awarded a grant of more than €30 million in the NWO call Roadmap Large-scale Scientific Infrastructure (GWI).

‘Microscopy is by far the least understood, most inefficiently operated, and the most abused of all laboratory instruments,’ reads the quote on the office wall of microscopy unit supporters Joost Willemse en Gerda Lamers. It describes exactly why the two developed the microscopy course for starting…

About forty microscopes, various laboratories, and some 15,000 zebrafish: that’s Sylvia le Dévédec's workplace. She is one of the managers of the Leiden Cell Observatory, a unique facility accessible to all researchers.

PhD defence

Lecture, Tuesday Talk

PhD defence

Physicist Sense Jan van der Molen researches materials that do not exist in nature. ‘It’s fascinating to see how the properties of a material change if we manage to make it super thin.’ He will give his inaugural lecture on 21 October.

To understand how the brain works, it is essential to map it out in detail. This appears to be possible with a microscopy technique in which Leiden physicists excel. This breakthrough could significantly advance the human quest to understand brain functions.

Biophysicist Alireza Mashaghi and his collaborators are taking up the fight against muscular dystrophy: genetic disorders that cause muscle weakness. They want to inhibit the clumping of proteins that results in toxic aggregates. For this, the team receives 550,000 euros from Health Holland. The team…

White clouds of ice-cold gas flowing across the floor. Magical, but be careful not to freeze your fingers off. We are of course talking about liquid nitrogen and helium. You may have seen the spectacular Freezing Physics science show by the student organisation Rino. But did you know that this commodity…

Moving an electron microscope of 2000 kg is a delicate challenge. The highly sensitive instrument needed to be moved to a new measurement hall, but even a tiny bump could damage it. After a few nerve-racking weeks of preparing the move and reinstalment, the researchers finally have a verdict: the instrument…

Assistant professor Joost Willemse firmly believes that as a teacher, you’re never done learning. ‘Students ask questions about things you’ve never thought of yourself. Ultimately, that makes you better at your job.’ That’s why he always encourages his students to ask questions. And it’s appreciated:…

It's time for the 2021 Image Award

Understanding the behaviour of tiny droplets in our cells could aid the search for new treatments. A team of Leiden researchers has developed a groundbreaking method to study how these droplets transition from liquid to solid. This change plays a role in various diseases, including neurodegenerative…

The guardian of our genome, the protein MutS, scans the DNA for spelling errors and makes sure they are corrected. An essential process for our health. Researchers at Leiden University Medical Centre (LUMC) have discovered precisely how this protein works by making MutS visible with cryo-electron microscopy.…

Leiden researchers have found clues to why a rare pregnancy disorder is mild in some babies but life-threatening in others. Their discovery opens the door to a test that could identify severe cases during pregnancy. Fortunately, a treatment already exists.

A microscope with incredible sharpness that leaves samples unharmed – Guido Stam helped develop one. During his PhD research, he combined light and electrons to study biological samples. ‘We can now measure things that simply weren’t possible before.’

Working in a laboratory is different from working in an office. Some of the rules that apply when working in or around a laboratory are given below.

A passion for video games, visuals and science: it almost seems impossible to bring all of this together. Yet, scientific animator Vera Williams found that dream combination at NeCEN's microscopy lab. 'An image or animation can help clarify the content of complex research.'

Multidrug-resistant pathogens and worldwide pandemics are increasing, making infectious diseases more prevalent. To develop new treatments, deeper knowledge of the interaction between bacteria and human cells is required. Ariane Briegel recently became a Medical Delta professor and studies such path…

Jasper Knoester is the dean of the Faculty of Science. How is he doing, what exactly does he do and what does his day look like? In each newsletter, Jasper gives an insight into his life.

The Phase 3 clinical trial results of the promising Covid-19 vaccine of Johnson & Johnson are expected this month. The Dutch electron microscopy facility NeCEN helped develop the company’s vaccine, and they have now published their scientific findings in Nature Communications.

Five projects with researchers from Leiden University have received a grant from the Dutch Research Council (NWO) to build or upgrade existing research facilities.

Physicist Milan Allan will build an instrument that will bring superconductivity research further. He has been awarded an ERC Consolidator Grant of 2 million euros over the next five years. With his PairNoise programme he aims to detect paired electrons as they occur just above the temperature at which…

On the 6th and 7th of September 2023, the Leiden Academic Centre for Drug Research (LACDR) organized the Leiden Bio-AFM workshop in cooperation with Bruker Nano GmbH (Germany) and Bruker Nederland BV. The organization of this event was led by the Medical Systems Biophysics and Bioengineering group (Alireza…

Dr. Sylvia Le Dévédec has been awarded an OSCARS grant for the project BIO-CODES. OSCARS, a four-year Horizon Europe initiative, promoting the adoption of Open Science in Europe by building on the successes of world-class European Research Infrastructures (RIs) in the ESFRI roadmap and beyond. Among…

From 22 to 24 October, researchers of the MARBLES-project informed museum visitors about microbes: bacteria and fungi that live all around us. The event was organised around the Micro-day of Leiden, which is this year’s EU City of Science.

What started with an old Soviet camera and a darkroom in London grew into a lifelong passion. Developmental biologist Michael Richardson has been capturing nature - from wild coastal plants to microscopic details in the lab - since his childhood.

Jasper Knoester, decaan van de Faculteit Wiskunde & Natuurwetenschappen, blikt terug op 2025 in "het jaar van Jasper".

Physicists in Leiden have built a microscope that can measure no fewer than four key properties of a material in a single scan, all with nanoscale precision. The instrument can even examine complete quantum chips, accelerating research and innovation in the field of quantum materials.

As of 1 September, Jeroen van Zon started as professor by special appointment in Quantitative Developmental Biology at the Institute of Biology Leiden (IBL). Van Zon is also group leader of Quantitative Developmental Biology at the physics research institute AMOLF. Three questions about his new role…

The Dutch Research Council (NWO) has granted four grants to Leiden humanities scholars. They get to spend this money on research on a topic of their choice, without thematic preconditions.

How can you ensure that more experimental drugs reach the finish line? At the moment, only one in twenty cancer drugs that are tested on humans makes it to the market. This is an enormous loss for patients and society. With a grant from the National Growth Fund, Oncode-PACT aims to efficiently select…

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