Atherosclerosis is the most important underlying process that drives cardiovascular disease, and is characterized by an accumulation of cholesterol which triggers an inflammatory response in the vessel wall.

PhD defence

Promotor: A.H. Meijer, Co-promotor: B.E. Snaar-Jagalska

This dissertation combines the use of defined microenvironments, high-resolution fluorescence microscopy, and time-resolved analysis, to study intracellular and cellular motility.

How do macrophages and neutrophils contribute to metastatic onset?

What are the biological and biophysical mechanisms that control chemokine gradient sensing and migration of immune, endothelial, and tumour cells in tumour development?

Promotor: T. Schmidt, Co-Promotor: B.E. Snaar-Jagalska

This thesis tackles the difficulty of predicting the liver’s clinical response to novel therapies, a challenge arising from interspecies differences and limitations of existing in vitro models.

Bispecific antibodies with one Fab arm binding to effector cells, such as T-cells and NK-cells, while the other Fab arm recognizing a tumor associated antigen (TAA) can be used to redirect these effector cells for tumor specific killing. Using bispecific antibodies to treat hematological cancers is…

PhD defence

Prostate cancer (PCa) is one of the most prevalent cancer in males.

Promotor: J.A. Bouwstra Co-promotor: A. El Ghalbzouri

Enabling volume-restricted metabolomics using next-generation microscale analytical tools.

Microbial rhodopsins are photosensitive pigments implemented in the growth and adaptation of a large population of microorganisms.

G protein-coupled receptors (GPCRs), one of the largest families of membrane proteins, are responsive to a diverse set of physiological endogenous ligands including hormones and neurotransmitters.

In this research project, we aimed to obtain more insight in the role of mast cells in the immune driven disorders rheumatoid arthritis and atherosclerosis.

Can Cyanobacteria be engineered to convert the greenhouse gas carbon dioxide into the valuable chemical isoprene?

PhD defence

PhD defence

Systems are called real-time systems, if the correctness of the system does not only depend on the correctness of the system output but also on whether the output is delivered on time.

Plants, algae and cyanobacteria have the amazing capacity to perform delicate photophysical and photochemical processes of light capture, excitation transfer, charge separation and catalysis in fluctuating living environments. As a consequence, photosynthetic proteins and membranes form dynamic architectures.…

Research question

Lecture

Lecture

The opening times of the Humanities buildings vary. The Lipsius building is opened during evenings as well, the other faculty buildings retain office hours.

Contemporary Maya Calendars

This thesis explored the molecular pharmacological mechanisms of targeting CB2R via investigation of novel drug discovery concepts such as target binding kinetics, allosteric modulation and biased signaling.

Time schedule

Discover the power of interdisciplinary AI research at Leiden University's SAILS Initiative through this bi-weekly seminar. The SAILS network of AI experts spans all seven faculties: Law, Science, Archaeology, Social Sciences, Humanities, Governance and Global Affairs, and the Leiden University Medical…

A study concerning the collective memory in the region of the Bene lo Ya/ Ene lo I'ya, Sierra Norte, Oaxaca.

With tomography it is possible to reconstruct the interior of an object without destroying.

Predictive maintenance (PdM) is a maintenance policy that uses the past, current, and prognosticated health condition of an asset to predict when timely maintenance should occur.

Understanding the temporal modes of digital mapping.

Mining time series is a machine learning subfield that focuses on a particular data structure, where variables are measured over (short or long) periods of time.

Promotor: Prof.dr. R. Verpoorte, Co-promotores: Dr. Y.H.Choi, N.R. Mustafa

The neolithization of the southern Netherlands in an antropological and geographical perspective

Increased public trust in law, government and democracy.

This research hopes to contribute to social awareness of the consequences of colonialism for Indigenous Peoples, to the deconstruction of still existing colonial and discriminatory notions and to a better appreciation of Indigenous art and thought.

Promotor: H.J. van den Herik, B.R. Katzy, Co-promotor: K. Sailer

The biweekly Lunch Time Seminar is an online only event, but it is not publicly accessible in real-time. If you would like to attend one of the upcoming sessions, please send an email to sails@liacs.leidenuniv.nl.

PhD defence

Un)timely Crises explores how ‘crisis’—as a narrative, concept, grammar, and experience—structures time and space. This collectively written volume extends Bakhtin’s ‘chronotope’ to challenge mobilizations of crisis within neoliberal governmentality. The book explores how contemporary crises can trigger…

Leiden Embedded & Real-time Computing (LERC) is an expert lab and leader in advanced research on embedded and real-time systems and software. The main mission of LERC is by its research to contribute in a highly innovative way to the system-level design of embedded and cyber-physical systems and software…

This book explores how ‘crisis’ - as a narrative, concept, grammar, and experience - structures time and space.