739 search results for “title microenvironment” in the Public website
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mechanistic studies revealing a protective role in the plaque microenvironment
Atherosclerosis is the most important underlying process that drives cardiovascular disease, and is characterized by an accumulation of cholesterol which triggers an inflammatory response in the vessel wall.
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Tailor-Made: Leveraging the Tumor Microenvironment to Boost Treatment for Advanced Liver Cancer
PhD defence
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Cell-autonomous and host-dependent CXCR4 signaling in cancer metastasis: insights from a zebrafish xenograft model
Promotor: A.H. Meijer, Co-promotor: B.E. Snaar-Jagalska
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Role of leukocytes in metastasis formation in a zebrafish
How do macrophages and neutrophils contribute to metastatic onset?
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Role of Chemokine Gradient Sensing in Ewing Sarcoma Progression, Angiogenesis and Immune Targeting
What are the biological and biophysical mechanisms that control chemokine gradient sensing and migration of immune, endothelial, and tumour cells in tumour development?
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Biophysical studies of intracellular and cellular motility
This dissertation combines the use of defined microenvironments, high-resolution fluorescence microscopy, and time-resolved analysis, to study intracellular and cellular motility.
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Outstanding Academic Titles for 2010
Cambridge History of South Africa, volume 1: From early times to 1885 (edited by Carolyn Hamilton, Bernard K. Mbenga, and Robert Ross) made Choice magazine's list of Outstanding Academic Titles for 2010.
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Mechanisms of Ewing sarcoma metastasis: biochemistry and biophysics
Promotor: T. Schmidt, Co-Promotor: B.E. Snaar-Jagalska
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Microphysiological liver systems for in vitro modeling and industry implementation
This thesis tackles the difficulty of predicting the liver’s clinical response to novel therapies, a challenge arising from interspecies differences and limitations of existing in vitro models.
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Leiden University publishes the titles of seven tainted scientific articles
In a supplementary decision on 17 May 2022, the Executive Board of Leiden University has concluded that it will publish the titles of seven articles in which there is evidence of malpractice. This concerns a former staff member of the Institute of Psychology. The Executive Board considers it to be in…
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Dissecting the immune microenvironment of breast cancer
PhD defence
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Zebrafish xenograft model: identification of novel mechanisms driving prostate cancer metastasis
Prostate cancer (PCa) is one of the most prevalent cancer in males.
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3D Image to Characterize and Optimize antibody-mediated antitumor immunity
Bispecific antibodies with one Fab arm binding to effector cells, such as T-cells and NK-cells, while the other Fab arm recognizing a tumor associated antigen (TAA) can be used to redirect these effector cells for tumor specific killing. Using bispecific antibodies to treat hematological cancers is…
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Development of human skin equivalents to unravel the impaired skin barrier in atopic dermatitis skin
Promotor: J.A. Bouwstra Co-promotor: A. El Ghalbzouri
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Improvisations in phototrophy
Microbial rhodopsins are photosensitive pigments implemented in the growth and adaptation of a large population of microorganisms.
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Microscale Analytical Tools
Enabling volume-restricted metabolomics using next-generation microscale analytical tools.
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C5 (Clever Combination of Synthetic Compartmentalization, Carbon Fixation and Compound Biomanufacturing)
Can Cyanobacteria be engineered to convert the greenhouse gas carbon dioxide into the valuable chemical isoprene?
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The good? The bad? The mutant! Characterization of cancer-related somatic mutations and identification of a selectivity hotspot in adenosine
G protein-coupled receptors (GPCRs), one of the largest families of membrane proteins, are responsive to a diverse set of physiological endogenous ligands including hormones and neurotransmitters.
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Mast cell-mediated immune modulation in experimental Rheumatoid Arthritis and Atherosclerosis
In this research project, we aimed to obtain more insight in the role of mast cells in the immune driven disorders rheumatoid arthritis and atherosclerosis.
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TGF-β and extracellular vesicles in the tumor microenvironment
PhD defence
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The Repercussions of Recognition - T cells in the tumor microenvironment
PhD defence
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Structure and regulation in photosynthesis
Plants, algae and cyanobacteria have the amazing capacity to perform delicate photophysical and photochemical processes of light capture, excitation transfer, charge separation and catalysis in fluctuating living environments. As a consequence, photosynthetic proteins and membranes form dynamic architectures.…
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Understanding the tumor microenvironment in glioblastoma for the development of focused therapies
PhD defence
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Programme
The focus will be on recent academic research in Literary Studies at the intersection with Digital Humanities. Lectures and interactive workshops will be given by experts in the field.
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Grants & Awards
Grants awarded to molecular physiology research
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UM Cure 2020: New therapies for uveal melanoma
Can we bring novel treatment options to the clinic for UM patients with liver metastases?
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Supramolecular materials: from biosensors to cell delivery devices
The group of Dr. Roxanne Kieltyka designs and synthesizes molecules that self-assemble into polymeric materials using specific non-covalent interactions. These substrates can be used for numerous applications in medicine ranging from disease detection to cell delivery depending on the (bio)molecular…
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Immune Activation and Tolerance
The Immune Activation and Tolerance group is headed by Dr. Bram Slütter. Vaccination is an experimental, but promising, treatment strategy for atherosclerosis. Previous work has shown that immunization of mice with modified LDL particles can reduce atherosclerotic lesion development, however such vaccines…
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International career
Are you considering a career outside of the Netherlands after following a Dutch bachelor ánd master programme? If so, then before your start your studies, make sure to check if your preferred country has special requirements to work as a psychologist, in addition to the Dutch title Master of Science…
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International career
Are you considering starting a master’s programme in Psychology at Leiden University and are you planning on pursuing a career outside of the Netherlands? If so, then before your start your studies, make sure to check if your preferred country has special requirements to work as a psychologist, in…
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International career
Are you considering starting a master’s programme in Psychology at Leiden University and are you planning on pursuing a career outside of the Netherlands? If so, then before your start your studies, make sure to check if your preferred country has special requirements to work as a psychologist, in…
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International career
Are you considering starting a master’s programme in Psychology at Leiden University and are you planning on pursuing a career outside of the Netherlands? If so, then before your start your studies, make sure to check if your preferred country has special requirements to work as a psychologist, in…
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International career
Are you considering starting a master’s programme in Psychology at Leiden University and are you planning on pursuing a career outside of the Netherlands? If so, then before your start your studies, make sure to check if your preferred country has special requirements to work as a psychologist, in…
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International career
Are you considering starting a master’s programme in Psychology at Leiden University and are you planning on pursuing a career outside of the Netherlands? If so, then before your start your studies, make sure to check if your preferred country has special requirements to work as a psychologist, in…
- Members (listed per university and category)
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LLX roundtable titled “Next Generation EU 2.0 – first steps towards a fiscally more integrated Eurozone?”
On Thursday 21 October 2021, the Europa Institute held a hybrid roundtable on the legal feasibility of financing future EU policies – such as EU Green Deal measures – through debts and of thereby extending the novel funding mechanism introduced by Next Generation EU (NGEU). This roundtable was organised…
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International career
Are you considering starting a master’s programme in Psychology at Leiden University and are you planning on pursuing a career in health care outside of the Netherlands? If so, then before your start your studies, make sure to check if your preferred country has special requirements to work as a psychologist,…
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Ministers of State
On 17 April, Evert-Jan Govaers defended the thesis 'Ministers of State. Unknown and desired; from stage to the wings?'.The doctoral research was supervised by Wim Voermans.
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Book on Immigrant Integration: “The Civic Citizens of Europe” by Moritz Jesse
Moritz Jesse, Associate Professor of EU Law at the Europa Institute, has published his book, “The Civic Citizens of Europe: The Legal Potential for Immigrant Integration in the EU, Belgium, Germany, and the United Kingdom”.
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Continuing your studies
Do you want to follow a full academic programme? If so, after obtaining your bachelor’s degree you can continue with a master’s programme. Once you have successfully completed your master’s you will have earned the title of Master of Arts (MA).
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Submission Guidelines
All manuscripts submitted to Inter-Section need to adhere to these guidelines. Since 01-08-2022 Inter-Section uses APA7 as a reference system. Inter-Section therefore now follows the new Faculty of Archaeology guidelines concerning referencing and bibliography.
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Van der Heijden Chair Social Justice
On the occasion of prof Paul van der Heijden’s stepping down as Rector Magnificus and President of the Executive Board of Leiden University in 2013 the Chair bearing his name on Social Justice was established. It was a “farewell present” of the Leiden University to it’s Rector.
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Summer and Winter Schools: Methodology & Statistics
The Graduate School of Social and Behavioural Sciences in collaboration with the Department of Methodology and Statistics and researchers in the field of Methodology and/or Statistics of the other Institutes provides training courses for PhD candidates and other researchers.
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Video
Watch our video about the activity programme titled Beyond Content: materiality of text and image and the in depth video's with our curators. (with subtitles in English)
- Invitation letters (for visa applications)
- Call for abstracts and papers
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Call for special sessions
We invite proposals for special sessions on interdisciplinary, under-studied, and emerging topics (deadline passed).
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Darién Profundo: A historical ecology approach to human practices in Gran Darién, Panama
How have human-environmental entanglements changed in the Gulf of San Miguel, Darien, Panama, from the first traces human practices through to the present?
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Using zebrafish to target the Achilles’ heel of cancer
Exploiting metabolic vulnerabilities to identify anticancer compounds in zebrafish synthetic lethality screens.
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Images Of The Indonesian War Of Independence, 1945-1949/Beelden Van De Indonesische Onafhankelijkheidsoorlog, 1945-1949/Perang Kemerdekaan Indonesia
Four years of protracted negotiations and bitter warfare passed between the declaration of Indonesian independence on 17 August, 1945, and the official transfer of sovereignty on 27 December, 1949.