Promotores: Prof.dr. C.A.J. Knibbe, Prof.dr. D. Tibboel (EMC, R’dam)

Having a chronic somatic condition can result in a variety of impairments in patients’ daily lives, including not only physical complaints such as pain, itch, and fatigue, but also problems of negative mood and impairments in social relationships. Next to disease characteristics, individual difference…

Promotor: J. van der Greef; Co-promotor: E. van Wijk, M. Wang

Imagine that you have a chronic skin condition, characterized by red patches of itchy, scaly skin. You regularly notice people staring at your skin and sense their reluctance to shake your hand. Or imagine that you have Parkinson's Disease, causing your hands to tremble and making it difficult for you…

What are the most important perpetuating factors of chronic fatigue and chronic fatigue syndrome, and which interventions are effective in influencing these factors?

Promotor: J. van der Greef, T. Hankemeier; Co-promotor: H.A. van Wietmarschen

Public sector decision-makers operate amidst an abundance of information and unclear political objectives. Attention is the sine qua non of policy-making: What is attended to can be addressed in policy responses; what is overlooked or goes unnoticed cannot. Despite its importance, public administration…

In this thesis, two potential therapeutic targets for diabetic nephropathy were dentified and investigated. First, we show that glomerular clusterin is upregulated in diabetic nephropathy and demonstrated that recombinant clusterin protein can protect the podocytes against oxidative stress in vitro.…

The major aim is to develop, evaluate, and implement disease-generic cognitive-behavioral interventions through the internet in order to optimize tailored health care for patients with chronic somatic conditions.

On 1 July 2020, Niek Strohmaier defended his thesis 'Making Sense of Business Failure'. The doctoral research was supervised by Prof. J.A.A. Adriaanse en dr. H. Pluut.

Dr. Nikki Ikani challenges binary views of intelligence warnings, proposing a multidimensional typology to evaluate warning effectiveness.

Chronic inflammatory skin diseases such as psoriasis and atopic dermatitis affect both the physical and psychological well-being of millions of patients, leading to persistent symptoms like itchiness and sleeplessness. These conditions often result in decreased productivity and quality of life overall,…

There are about 35,000 students with chronic illnesses in the Netherlands. If they cannot receive education in the classroom, they may be able to do so from home or a hospital with hybrid education. The question in this study is: how can interaction with the teacher and fellow students be promoted?

Persistent somatic symptoms are long term symptoms that lack a clear medical explanation. These symptoms have a high prevalence where most people know someone who experiences such symptoms or they experience such symptoms themselves. Symptoms can vary greatly in and between people. While one person…

The €6.24 million EU-funded research project QSPainRelief has kicked off. The project aims to help patients suffering from chronic pain with novel, personalised combinational treatments and is coordinated by Elizabeth de Lange from the Leiden Academic Center for Drug Research.

I want to understand the overlap between physical health, mental health, and healthy aging and whether/how stress (behaviorally and biologically) may tie these concepts together.

There is currently a disruption that prevents network access.

There is currently a disruption of several network services.

M. Danhof, Co-promotor: O.E. Della Pasqua

The Dutch Health and Youth Care Inspectorate (IGJ) has found that foster care at stitching Enver is not up to scratch. Mariëlle Bruning, Professor of Children and the Law, spoke to public broadcaster NOS about these new findings.

Student cooperativeness underlies high quality teacher-student relationships, and has been positively associated with students’ school engagement. Fostering cooperative rather than oppositional student behavior might be especially helpful for protecting at-risk students against academic failure.

The precise psychobiological mechanisms leading to chronic physiological stress responses have not been sufficiently explained, although stress is a major risk factor for disease and early death. A problem for conventional stress theory is that most of these responses seem to occur in situations without…

Kidney failure is a serious issue because kidneys cannot regenerate themselves after injury. A possible solution consists of artificially growing healthy kidney tissue. To achieve that, scientists first need to understand kidney development during the earliest stages, in the fetus. Leiden researchers…

Promotor: Prof.dr. M. Danhof

The Astronomy & Society group of Leiden Observatory takes a new turn in science: they have decided to share their rejected research proposals with the scientific community. ‘We put a lot of effort into them, and now hopefully others can benefit from our work. Maybe it even results in new collaborations,’…

Children are not always immediately helped due to staff shortages. For years, youth protection agencies have used an emergency protocol. Mariëlle Bruning, Professor of Children and the Law in ‘Trouw’: ‘It’s shocking that an emergency protocol has been used for three years.’

The Leiden University Medical Center (LUMC) is committed to improving healthcare and the health of individuals. The LUMC staff put this mission into practice on a daily basis with their leading research, cutting-edge teaching and optimal, innovative healthcare.

Dying from viral infection due to organ failure and blood loss: we still know little about how it can happen. Among other things, Huaqi Tang developed an organ-on-a-chip to figure it out. 'These technologies can offer unprecedented opportunities to fight the viruses that threaten our society.' Tang…

The aims of the project are to: further clarify 'inhibition by safety'; explore and describe all possible sagety factors, with a special focus on the primary human safety source: social connectedness; reviewing prolonged stress responses without stressors.

Promotor: S.M. Verduyn Lunel

The Second Chance project aims to promote recovery and re-integration of entrepreneurs who have recently undergone bankruptcy.

PhD defence

LUMC researchers are looking for factors that point to illness at an early stage.

LUMC researchers are looking for factors that point to illness at an early stage.