19 search results for “hubrecht” in the Public website
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Advisory Board
The Advisory Board of the IBL consists of five eminent scientists with specialist expertise in complementary disciplines. They all have prominent positions for the field of Biology in the Netherlands outside our own institute.
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Collaborations
Find out more about our national and international research collaborations.
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Prediction of human gut (colon cancer) target site concentrations and PKPD relationships
The advanced insights obtained for the CNS PBPK model development are currently used to develop advanced mathematical models for drug distribution prediction in other body tissues protected by barriers, such as the gut. The gut PBPK model will be linked to drug effects for treatment of colon cancer.
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Witnessing the Process of Bacterial Cell Death: Novel Antimicrobials and Their Mechanisms of Action
This thesis describes the antimicrobial discovery strategy developed in our group, the den Hertog Group at the Hubrecht Institute. It includes a cultivation-based screening approach for novel antimicrobial agents from the source of fungi, and a bacterial time-lapse imaging approach for antimicrobial…
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Pursuing new anti-cancer therapy as a team
Cancer is the leading cause of death in the Netherlands, and, with over 100 different types of cancer, it’s not a simple disease. Today, skin, breast, lung, prostate and colon cancer are the most diagnosed forms. Therefore, the discovery and development of new drugs has the ability to significantly…
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Leiden: The scene of the Zebrafish Disease Models conference 2018
In July, 2018, the Institute of Biology Leiden hosted the 11th conference of the Zebrafish Disease Models Society (ZDMS), an international association dedicated to the advancement of basic and clinical research using zebrafish disease models. More than 350 researchers from all over the world gathered…
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Snake venom glands grown in lab
For the first time, researchers were able to grow organoids from snake venom glands. The lab-grown 3-D structures can produce snake venom molecules. This is a major step in finding treatments to tackle snakebite, which causes over 100,000 deaths each year. Publication in top journal Cell.
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Annual IBL symposium about Biological Networks
On Friday the 6th of December, the annual symposium of the IBL was organized at the Buruma theatre (LUMC), Leiden. This year’s theme was “Biological Networks from Molecules to Society”.
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Research
The current projects of the Molecular Physiology group focus on proteins of the endocannabinoid system, kinases and antibacterial targets. MSc- and BSc-students can contact Jessica van Krimpen-Kraaijenoord to apply for research internships.
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The Netherlands becomes global player organ-on-chip technology
Organ-on-chip technology is used in drug research and customized treatments for patients. Research Institutes and industry join forces within the Institute for human Organ and Disease Model Technologies (hDMT) that was officially launched on May 18. Combining facilities, people and expertise will allow…
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Almost 19 million euros for development and study of organs-on-chips
It sounds futuristic, but it is possible: the creation of miniature organs of patients in order to study them and see how diseases develop and can be treated. This is what researchers from the LUMC, Twente University (UT), UMCG, TU Delft and the Hubrecht Institute hope to achieve in the next ten years…
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Proteins and DNA loops: Science-Groot grant for Remus Dame
How do our cells keep DNA stored away? To find out, biochemist Remus Dame received a 3 million euro Science-Groot grant. Leiden University will share the grant with TU Delft, VU Amsterdam and the Hubrecht Institute.
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Leiden biology appreciated with large NWO grants
A Vici grant and a Science-GROOT: scientists from the Institute of Biology Leiden have been awarded prestigious grants from the Dutch Research Council (NWO). From investigating bacteria without cell walls to harnessing plants with the help of microorganisms.
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Leiden breakthrough in research on nanotherapy
Nanoparticles that transport medicines to a specific part of the human body are usually broken down in the liver prematurely. Jeroen Bussmann from Leiden University has discovered a new method to prevent this from happening. Publication in ACS Nano.
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Seventeen million for Dutch X-omics Initiative
The Dutch X-omics Initiative has received seventeen million euros from NWO as part of the National Roadmap for Large-Scale Infrastructure. Leiden University’s metabolomics research led by Thomas Hankemeier is one of the participators.
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Research projects
An overview of research projects at the Predictive Pharmacology group.
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Gravitation grants for three major research programmes
Three major research projects involving Leiden scientists have been awarded a grant from NWO’s Gravitation Programme. The projects are on innovation processes, organs-on-chips and quantum software.
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Two research schools partnered with Leiden University participate in Graduate Programme
The Casimir Research School and the Graduate School Experimental Plant Sciences will be participating in the first Graduate Programme. This was announced on Wednesday 12 August by Minister Plasterk (Ministry of Education, Culture and Science). Leiden University is a partner in both schools. Nine Dutch…
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Hall of Fame 2020
In 2020, many of our staff and students have again won prestigious prizes and been awarded important research subsidies.