In this research group, led by Dr. Joost Beltman, the aim is to employ mathematical and computational dynamical modelling approaches in order to quantitatively and mechanistically understand the dynamical behaviour and regulation of intracellular networks of genes, proteins and metabolites as well as…

Analysis of drug adversity

Microscopic insight on lipid-based nanomedicine in vivo remains limited to the perception of the knowledge that could be obtained: if we interpret only what we see, then we only believe to know. Although believing to know encapsulates an undefined amount of uncertainty in the exploration of lipid-based…

The main aim of this thesis was to unravel the signaling and regulatory networks that drive tumor cell migration during breast cancer metastasis.

Our research in the area of safety sciences aims to increase the mechanistic understanding of cellular toxicity of drugs and, in a broader sense, chemicals.

Sewer pipes are an essential infrastructure in modern society and their proper operation is important for public health. To keep sewer pipes operational as much as possible, periodical inspections for defects are performed.

The Chemical Biology & Immunology (CBI) group is headed by Prof. Sander van Kasteren and Prof. Kim Bonger.

From Incident to Precedent

PhD defence

On 9 November, Jonathan Hak defended the thesis 'Non-textual evidence in international criminal prosecutions: discovering the best practices for audiovisual materials in a digital age'. The doctoral research was supervised by Carsten Stahn and Jens Iverson.

Estudio arqueológico de la primera ciudad española en la Tierra Firme de América: Santa María de la Antigua del Darién

We focus on a better understanding of the mechanisms of cancer drug resistance and metastasis.

In this project, we aim to develop mathematical models to mechanistically and quantitatively predict the dynamics of cellular stress pathway activation and its relation with toxic effects when cells are exposed to various toxicants.

The research within the Division of Cell Systems and Drug Safety, headed by Prof. Bob van de Water, is focused on novel therapeutic modalities and novel concepts in early drug discovery, in order to develop more effective and safer therapeutic strategies. We generate advanced cell and computational…

Research at the SBC group is comprised of the following research themes:

This project addresses the occurrence of political and ideological biased crimes in light of the recent migration influx in European countries.

Although sexual abstinence before marriage is no longer the central message in The Netherlands the affective relationship as a criterion for professionals within criminal justice can be seen as a more contemporary version of marriage.

PhD defence

The research conducted at the Leiden Academic Centre for Drug Research is clustered within the divisions of BioTherapeutics, Cell Systems and Drug Safety, Medicinal Chemistry and Systems Pharmacology and Pharmacy, and the Metabolomics and Analytics Centre.

In this project, we aim to obtain a quantitative understanding of the role of the immune system in tumor regression, of the role of tumor cell heterogeneity in cancer growth and of tumor cell migration properties.

The master's specialisation in Visual Ethnography emphasises a strongly hands-on, empirical approach, which requires students to play an active role in mastering the audiovisual toolbox.

Steering soil microbiomes for better crop quality: the holy grail to improve human health?

The Urban Studies bachelor’s programme is based on two learning trajectories. One trajectory focuses on in-depth knowledge of urban issues; the other develops your methodological, academic and professional skills.

In the Netherlands judges are not the only ones to impose sentences. The Public Prosecution Service and the authorities can also pass sentences. Experts from Leiden research how these sentencing processes work and how they can be improved in order to protect the legal status of the public.

This project aims to improve understanding of, and responses to, the phenomenon of lone actors through analysis of comprehensive data on cases from across Europe.

When do we say violence was used in an incident? The answer may seem obvious at first. But interim results from a study by Jolien van Breen show that Dutch people are labelling events in increasingly broad contexts as violent.

Leiden University mourns the victims of the terrorist attacks in Brussels. These attacks are an assault on our democratic society. We will continue to defend our European values of freedom and tolerance against all attempts to undermine them.

The Role of Law in Libya’s National Reconciliation (RoLLNaR) was a research project that ran from 2017 to 2020. It identified and assessed the role of law – both actual and potential, enabling and constraining – with regard to major challenges of reconciliation in Libya. The project was led by Dr. Suliman…

Subproject of

What is the nature and scope of violence? Who offends, and in what context? Who are the victims? And how can we design suitable intervention and prevention strategies? In this track, you will be familiarised with the many faces of violent offending, to provide the knowledge and tools to understand,…

World War II is never over for those who have lived through it. This is the conclusion of Cleveringa Professor Carol Gluck and her students after reading The Assault (De Aanslag) by Harry Mulisch. The book played a central role in Gluck’s honours course.

The Dutch Public Prosecution Service (OM) will handle more criminal cases without involvement of the courts. The aim: more community service and fewer prison sentences. Jan Crijns, Professor of Criminal and Criminal Procedural Law, commented on the proposal in ‘Trouw’ newspaper.

Crime victims cannot always fully exercise their rights, said Maarten Kunst, Professor of Criminology, in his inaugural lecture on 26 October. His mission is to find out why exactly this is and to see whether change can be brought about.

A research into homicide.

Young people are more likely to find long texts unappealing to read, particularly with all the digital distractions. To improve young people’s reading skills, Elise Swart and Hannah De Mulder are starting an innovative study to make reading fun again.

On Friday, April 5, the Ecuadorian police stormed the Mexican Embassy in Quito to arrest former Ecuadorian vice president Jorge Glas Espinel.

Natalia Sobrino-Saeb has attended the Nobel Peace Prize award ceremony in Oslo. She was awarded this honour after winning the essay competition of the Nobel Ignitor Fellowship, a programme that seeks to inspire young changemakers around the world – for change can be made by all of us: “You never know…

Should we be deeply concerned about the America of Donald Trump? Or will he bring about positive change? This was the main topic of discussion between researchers and students at the Big Leiden Presidential Breakfast on 9 November.

Violence such as assault or head-butting causes pain, shock and distress. It is often seen as savage or senseless. But for those who commit it, violence has meaning, argues violence researcher Don Weenink in his inaugural lecture.

Lecture

In this blog post, Linda Slapakova discusses the various roles that AI plays in counter-disinformation efforts, the prevailing shortfalls of AI-based counter-disinformation tools and the technical, governance and regulatory barriers to their uptake, and how these could be addressed to foster the uptake…

Lecture